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ONTOLOGY REPORT - ANNOTATIONS


Term:response to pH
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Accession:GO:0009268 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.


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response to pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 IDA RGD PMID:15613469 RGD:1598638 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510
JBrowse link
G Arsa arylsulfatase A IDA RGD PMID:6137211 RGD:1599227 NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783
JBrowse link
G Arsb arylsulfatase B IDA RGD PMID:6137211 RGD:1599227 NCBI chr 2:25,002,210...25,162,675
Ensembl chr 2:25,002,346...25,162,671
JBrowse link
G Car2 carbonic anhydrase 2 IEP RGD PMID:8141264 RGD:1600724 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Clcn7 chloride voltage-gated channel 7 IDA RGD PMID:11846422 RGD:1600865 NCBI chr10:14,151,758...14,177,130
Ensembl chr10:14,151,758...14,177,130
JBrowse link
G Clcnka chloride voltage-gated channel Ka IEP RGD PMID:7814604 RGD:2313585 NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
JBrowse link
G Gba glucosylceramidase beta IDA RGD PMID:15191554 RGD:5508436 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Gja1 gap junction protein, alpha 1 IDA RGD PMID:14699011 RGD:1582694 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gja3 gap junction protein, alpha 3 IDA RGD PMID:11889584 RGD:1599826 NCBI chr15:31,181,360...31,206,808
Ensembl chr15:31,181,369...31,206,810
JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 involved_in ISO (MGI:3623706|PMID:16556803) RGD PMID:16556803 MGI:3623706 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 IDA RGD PMID:12719228 RGD:1581586 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198
JBrowse link
G P2rx5 purinergic receptor P2X 5 IDA RGD PMID:12237343 RGD:727431 NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423
JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase IDA RGD PMID:11395514 RGD:2302422 NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965
JBrowse link
G Sts steroid sulfatase IDA RGD PMID:6586719 RGD:1601410 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402
JBrowse link
G Tg thyroglobulin IDA RGD PMID:12809172 RGD:1600143 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 acts_upstream_of_or_within IEP
IDA
ISO
PMID:10201375
MGI:1934023 (MGI:1355140|PMID:10764638)
RGD PMID:10764638 PMID:16191202 PMID:10201375 MGI:1355140, RGD:2317113, RGD:70055 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
G Ttpa alpha tocopherol transfer protein IDA RGD PMID:14531858 RGD:1600431 NCBI chr 5:33,497,537...33,518,936
Ensembl chr 5:33,497,137...33,518,073
JBrowse link
cellular response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asic2 acid sensing ion channel subunit 2 IDA RGD PMID:12736332 RGD:1298620 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 IEP RGD PMID:26033523 RGD:13204712 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Impact impact RWD domain protein involved_in ISS
ISO
GO_REF:0000024
(MGI:5576818|PMID:24333428)
UniProt
RGD
PMID:24333428 GO_REF:0000024 MGI:5576818 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:8458414 RGD:7243874 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G LOC686596 similar to aquaporin 10 involved_in ISO (PMID:30420639) RGD PMID:30420639 NCBI chr 2:175,402,609...175,407,677
Ensembl chr 2:175,403,263...175,406,815
JBrowse link
G Pkd1l3 polycystin 1 like 3, transient receptor potential channel interacting involved_in
NOT|involved_in
ISO (MGI:5315344|PMID:16891422)
(MGI:4888566|PMID:20605874)
RGD PMID:16891422 PMID:20605874 MGI:4888566 MGI:5315344 NCBI chr19:37,585,564...37,650,083
Ensembl chr19:37,585,725...37,650,155
JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel involved_in ISO (MGI:5315344|PMID:16891422), (MGI:6149416|PMID:29567962) RGD PMID:16891422 PMID:29567962 MGI:5315344 MGI:6149416 NCBI chr 1:243,032,853...243,070,031
Ensembl chr 1:243,032,913...243,070,031
JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISO
ISS
(PMID:20717956)
GO_REF:0000024
RGD
UniProt
PMID:20717956 GO_REF:0000024 NCBI chr 7:14,521,448...14,534,589
Ensembl chr 7:14,521,368...14,534,593
JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 involved_in ISO (PMID:20717956) RGD PMID:20717956 NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741
JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISS
ISO
GO_REF:0000024
(PMID:24840010)
UniProt
RGD
PMID:24840010 GO_REF:0000024 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 involved_in ISO
IDA
(PMID:11226139) RGD PMID:11226139 PMID:11226139 RGD:11535102 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
JBrowse link
cellular response to alkaline pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gh1 growth hormone 1 IEP RGD PMID:23639351 RGD:10003149 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Insrr insulin receptor-related receptor involved_in ISO (PMID:21641549)
(MGI:5288297|PMID:21641549)
RGD PMID:21641549 MGI:5288297 NCBI chr 2:173,255,335...173,274,800
Ensembl chr 2:173,255,414...173,274,800
JBrowse link
G Kcnk4 potassium two pore domain channel subfamily K member 4 involved_in IDA PMID:15677687 UniProt PMID:15677687 RGD:10047327 NCBI chr 1:204,117,941...204,129,494
Ensembl chr 1:204,114,572...204,125,925
JBrowse link
cellular response to pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asic1 acid sensing ion channel subunit 1 involved_in ISO
ISS
(PMID:22760635)
GO_REF:0000024
RGD
UniProt
PMID:22760635 GO_REF:0000024 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
JBrowse link
G Gja1 gap junction protein, alpha 1 involved_in ISO (MGI:5882903|PMID:14699011) RGD PMID:14699011 MGI:5882903 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gna11 G protein subunit alpha 11 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5444590|PMID:22733973)
Ensembl
RGD
PMID:22733973 GO_REF:0000107 MGI:5444590 NCBI chr 7:8,163,752...8,177,636
Ensembl chr 7:8,162,750...8,179,812
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO
IEA
ISS
(PMID:17761367)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17761367 GO_REF:0000024 GO_REF:0000107 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Gpr68 G protein-coupled receptor 68 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:5445001 (MGI:5444590|PMID:22733973)
RGD PMID:22733973 PMID:21873635 MGI:5444590, RGD:13792537 NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089
JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 involved_in ISO (PMID:22020278) RGD PMID:22020278 NCBI chr12:34,341,673...34,370,010
Ensembl chr12:34,335,190...34,370,141
JBrowse link
G Hyal1 hyaluronidase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19478093)
UniProt
Ensembl
RGD
PMID:19478093 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:108,250,654...108,254,526
Ensembl chr 8:108,250,667...108,260,210
JBrowse link
G Kcnk18 potassium two pore domain channel subfamily K member 18 involved_in ISO (PMID:12754259) RGD PMID:12754259 NCBI chr 1:258,374,671...258,388,945
Ensembl chr 1:258,374,671...258,388,945
JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in ISO (MGI:6103412|PMID:29019981) RGD PMID:29019981 MGI:6103412 NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252
JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel involved_in ISO (MGI:6245961|PMID:28904867) RGD PMID:28904867 MGI:6245961 NCBI chr 1:243,032,853...243,070,031
Ensembl chr 1:243,032,913...243,070,031
JBrowse link
cellular stress response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:10615049)
Ensembl
RGD
PMID:10615049 GO_REF:0000107 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236
JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pck1 phosphoenolpyruvate carboxykinase 1 acts_upstream_of_or_within ISO (MGI:3851650|PMID:19458124) RGD PMID:19458124 MGI:3851650 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G Slc38a3 solute carrier family 38, member 3 acts_upstream_of_or_within ISO (MGI:3851650|PMID:19458124) RGD PMID:19458124 MGI:3851650 NCBI chr 8:108,323,889...108,339,959
Ensembl chr 8:108,323,894...108,339,988
JBrowse link
response to acidic pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan IEP RGD PMID:19133233 RGD:2315756 NCBI chr 1:132,981,034...133,044,416
Ensembl chr 1:132,981,582...133,043,627
JBrowse link
G Asic1 acid sensing ion channel subunit 1 acts_upstream_of_or_within ISO MGI:2179834 (MGI:2158965|PMID:11854527), (MGI:2179183|PMID:11988176) RGD PMID:11854527 PMID:11988176 MGI:2158965 MGI:2179183 NCBI chr 7:130,798,317...130,828,535
Ensembl chr 7:130,799,917...130,828,541
JBrowse link
G Asic2 acid sensing ion channel subunit 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180111 (MGI:1933515|PMID:11306621), (MGI:2158965|PMID:11854527)
Ensembl
RGD
PMID:11306621 PMID:11854527 GO_REF:0000107 MGI:1933515 MGI:2158965 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424
JBrowse link
G Asic3 acid sensing ion channel subunit 3 acts_upstream_of_or_within ISO
IDA
MGI:2429689|MGI:2451051 (MGI:2155574|PMID:11754838), (MGI:2158965|PMID:11854527), (MGI:2450005|PMID:12060708)
PMID:9261094
RGD PMID:11754838 PMID:11854527 PMID:12060708 PMID:9261094 MGI:2155574 MGI:2158965 MGI:2450005, RGD:1299543 NCBI chr 4:10,760,509...10,764,987
Ensembl chr 4:10,760,597...10,764,643
JBrowse link
G Ctss cathepsin S involved_in ISO
IEA
(PMID:22864553)
GO_REF:0000107
RGD
Ensembl
PMID:22864553 GO_REF:0000107 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Gip gastric inhibitory polypeptide IMP HCl RGD PMID:34554 RGD:2312536 NCBI chr10:80,968,410...80,976,506
Ensembl chr10:80,968,352...80,976,503
JBrowse link
G Gpr151 G protein-coupled receptor 151 involved_in ISO (PMID:31119277) RGD PMID:31119277 NCBI chr18:34,568,907...34,570,301
Ensembl chr18:34,568,907...34,570,301
JBrowse link
G Gpr31 G protein-coupled receptor 31 involved_in ISO (PMID:31119277) RGD PMID:31119277 NCBI chr 1:52,926,953...52,927,912 JBrowse link
G Gpr4 G protein-coupled receptor 4 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:12955148), (PMID:17462861), (PMID:22110680)
MGI:3700206 (MGI:3699048|PMID:17145776)
GO_REF:0000024
RGD
UniProt
PMID:12955148 PMID:17145776 PMID:17462861 PMID:22110680 GO_REF:0000024 MGI:3699048 NCBI chr 1:78,865,376...78,877,126
Ensembl chr 1:78,865,409...78,876,599
JBrowse link
G Gpr65 G-protein coupled receptor 65 involved_in ISO (PMID:15618224) RGD PMID:15618224 NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512
JBrowse link
G Lgmn legumain involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:18374643)
GO_REF:0000107
MGI:2676125 (MGI:3796729|PMID:18374643)
(MGI:5702834|PMID:25326800)
(PMID:9065484)
RGD
Ensembl
PMID:9065484 PMID:18374643 PMID:25326800 GO_REF:0000107 MGI:3796729 MGI:5702834 NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase IEP HCl RGD PMID:7729276 RGD:2317551 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
JBrowse link
G Serpinf1 serpin family F member 1 IEP RGD PMID:19575033 RGD:8554877 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) IEP RGD PMID:10600930 RGD:13208945 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in
acts_upstream_of_or_within
IDA
ISO
ISS
PMID:18321853
MGI:2429323 (MGI:1353365|PMID:10673550)
(PMID:8901634)
GO_REF:0000024
RGD
UniProt
PMID:8901634 PMID:10673550 PMID:18321853 GO_REF:0000024 MGI:1353365, RGD:8554433 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:12081562 RGD:634206 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476
JBrowse link
G Sst somatostatin IEP HCl RGD PMID:18992283 RGD:2303157 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173
JBrowse link
G Stxbp2 syntaxin binding protein 2 IEP RGD PMID:15240346 RGD:2312428 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
JBrowse link
response to alkaline pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acer1 alkaline ceramidase 1 involved_in ISO (PMID:17713573) RGD PMID:17713573 NCBI chr 9:1,792,790...1,824,434
Ensembl chr 9:1,793,139...1,824,434
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) IEP RGD PMID:10600930 RGD:13208945 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    response to stimulus 10358
      response to abiotic stimulus 1530
        response to pH 57
          cellular response to pH + 27
          filamentous growth of a population of unicellular organisms in response to pH + 0
          modulation by symbiont of host response to pH 0
          response to acidic pH + 31
          response to alkaline pH + 5
          response to neutral pH + 0
paths to the root