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ONTOLOGY REPORT - ANNOTATIONS

Term:single fertilization
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Accession:GO:0007338 term browser browse the term
Definition:The union of male and female gametes to form a zygote.
Synonyms:related_synonym: zygote biosynthesis;   zygote formation
 only_in_taxon: NCBITaxon:2759 ! Eukaryota
 never_in_taxon: NCBITaxon:58024 ! Spermatophyta


show annotations for term's descendants           Sort by:
single fertilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACR acrosin involved_in ISO (MGI:3577815|PMID:15685642) UniProt PMID:15685642 MGI:3577815 NCBI chr22:30,978,598...30,985,739
Ensembl chr22:50,085,719...50,092,869 		JBrowse link
G ACTL7A actin like 7A involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:80,014,898...80,016,379
Ensembl chr 9:108,188,166...108,189,473 		JBrowse link
G ADCY3 adenylate cyclase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:24,812,729...24,913,539
Ensembl chr2A:24,908,108...25,009,163 		JBrowse link
G ANTXR2 ANTXR cell adhesion molecule 2 acts_upstream_of_or_within ISO (PMID:28604699) MGI PMID:28604699 NCBI chr 4:44,124,282...44,284,949
Ensembl chr 4:49,972,472...50,132,738 		JBrowse link
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30786955) Ensembl
MGI		 PMID:30786955 GO_REF:0000107 NCBI chr 5:37,015,518...37,305,769
Ensembl chr 5:37,503,162...37,840,205 		JBrowse link
G AR androgen receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21084446) Ensembl
MGI		 PMID:21084446 GO_REF:0000107 NCBI chr  X:56,722,828...56,909,004
Ensembl chr  X:66,791,081...66,969,357 		JBrowse link
G ASH1L ASH1 like histone lysine methyltransferase acts_upstream_of_or_within ISO (PMID:26333994) MGI PMID:26333994 NCBI chr 1:130,679,868...130,906,918
Ensembl chr 1:134,286,761...134,468,722 		JBrowse link
G CCDC136 coiled-coil domain containing 136 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:120,743,177...120,774,401
Ensembl chr 7:133,267,217...133,298,936 		JBrowse link
G CCDC146 coiled-coil domain containing 146 acts_upstream_of_or_within ISO (PMID:38038747) MGI PMID:38038747 NCBI chr 7:68,965,404...69,215,833
Ensembl chr 7:82,900,402...83,027,578 		JBrowse link
G CD46 CD46 molecule involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:183,330,423...183,373,916
Ensembl chr 1:188,031,758...188,182,046 		JBrowse link
G CD9 CD9 molecule involved_in IEA UniProt
Ensembl		 GO_REF:0000043 GO_REF:0000107 NCBI chr12:6,327,783...6,366,083
Ensembl chr12:6,245,348...6,283,385 		JBrowse link
G CFAP57 cilia and flagella associated protein 57 acts_upstream_of_or_within ISO (PMID:36752199) MGI PMID:36752199 NCBI chr 1:42,470,987...42,556,101
Ensembl chr 1:43,848,369...43,933,279 		JBrowse link
G CFAP70 cilia and flagella associated protein 70 acts_upstream_of_or_within ISO (PMID:37352829) MGI PMID:37352829 NCBI chr10:69,801,407...69,906,688
Ensembl chr10:72,260,229...72,360,714 		JBrowse link
G CLGN calmegin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22621904) Ensembl
MGI		 PMID:22621904 GO_REF:0000107 NCBI chr 4:132,756,193...132,794,805
Ensembl chr 4:144,060,656...144,099,419 		JBrowse link
G COL6A1 collagen type VI alpha 1 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28604699) Ensembl
MGI		 PMID:28604699 GO_REF:0000107 NCBI chr21:32,322,185...32,346,850
Ensembl chr21:45,584,096...45,607,240 		JBrowse link
G CR1L complement C3b/C4b receptor 1 like involved_in IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr 1:183,224,415...183,303,268
Ensembl chr 1:188,031,758...188,182,046 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28439006) Ensembl
MGI		 PMID:28439006 GO_REF:0000107 NCBI chr22:3,141,147...3,177,448
Ensembl chr22:19,632,359...19,668,858 		JBrowse link
G DRC1 dynein regulatory complex subunit 1 acts_upstream_of_or_within ISO (PMID:34169321) MGI PMID:34169321 NCBI chr2A:26,399,275...26,453,518
Ensembl chr2A:26,491,900...26,545,640 		JBrowse link
G FETUB fetuin B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:183,675,258...183,687,754
Ensembl chr 3:192,142,702...192,154,920 		JBrowse link
G FOXL2 forkhead box L2 acts_upstream_of_or_within ISO (PMID:24739304) MGI PMID:24739304 NCBI chr 3:135,968,040...135,980,063 JBrowse link
G HEXB hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12756243) Ensembl
MGI		 PMID:12756243 GO_REF:0000107 NCBI chr 5:40,589,448...40,625,176
Ensembl chr 5:41,199,681...41,232,693 		JBrowse link
G HOXA10 homeobox A10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23760953) Ensembl
MGI		 PMID:23760953 GO_REF:0000107 NCBI chr 7:27,815,112...27,818,829
Ensembl chr 7:27,415,833...27,423,580 		JBrowse link
G HOXA11 homeobox A11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23760953)
(PMID:7789268)		 Ensembl
MGI		 PMID:7789268 PMID:23760953 GO_REF:0000107 NCBI chr 7:27,826,003...27,829,757
Ensembl chr 7:27,424,759...27,429,103 		JBrowse link
G HOXA9 homeobox A9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23760953) Ensembl
MGI		 PMID:23760953 GO_REF:0000107 NCBI chr 7:27,806,942...27,810,304
Ensembl chr 7:27,405,931...27,409,984 		JBrowse link
G HOXD10 homeobox D10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23760953) Ensembl
MGI		 PMID:23760953 GO_REF:0000107 NCBI chr2B:63,395,636...63,399,704
Ensembl chr2B:181,104,876...181,110,963 		JBrowse link
G HOXD11 homeobox D11 acts_upstream_of_or_within ISO (PMID:23760953) MGI PMID:23760953 NCBI chr2B:63,386,806...63,398,777 JBrowse link
G HOXD9 homeobox D9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23760953) Ensembl
MGI		 PMID:23760953 GO_REF:0000107 NCBI chr2B:63,401,813...63,404,731
Ensembl chr2B:181,112,002...181,113,415 		JBrowse link
G HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO (PMID:30786955) MGI PMID:30786955 NCBI chr10:95,030,626...95,061,415
Ensembl chr10:98,526,113...98,552,922 		JBrowse link
G HYAL3 hyaluronidase 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:50,221,428...50,228,062
Ensembl chr 3:51,456,173...51,462,815 		JBrowse link
G IZUMO1 izumo sperm-oocyte fusion 1 involved_in ISO (MGI:5568137|PMID:24739963) UniProt PMID:24739963 MGI:5568137 NCBI chr19:45,740,372...45,747,177
Ensembl chr19:54,330,545...54,337,533 		JBrowse link
G IZUMO1R IZUMO1 receptor, JUNO involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:89,318,370...89,322,004
Ensembl chr11:92,805,614...92,807,669 		JBrowse link
G KDM5B lysine demethylase 5B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24802759) Ensembl
MGI		 PMID:24802759 GO_REF:0000107 NCBI chr 1:178,323,073...178,406,608
Ensembl chr 1:182,622,425...182,702,994 		JBrowse link
G KMT2C lysine methyltransferase 2C acts_upstream_of_or_within ISO (PMID:17021013) MGI PMID:17021013 NCBI chr 7:143,714,716...144,016,188
Ensembl chr 7:155,862,610...156,081,043 		JBrowse link
G LOC100970414 histone H3.3A acts_upstream_of_or_within ISO (PMID:25675407) MGI PMID:25675407 NCBI chr 1:201,523,670...201,533,005
Ensembl chr 1:206,520,109...206,529,447 		JBrowse link
G LOC100984709 C4b-binding protein alpha chain acts_upstream_of_or_within ISO (PMID:9890753) MGI PMID:9890753 NCBI chr 1:182,707,221...182,747,878
Ensembl chr 1:186,985,264...187,025,898 		JBrowse link
G LOC100988671 histone H3.3A acts_upstream_of_or_within ISO (PMID:25675407) MGI PMID:25675407 NCBI chr17:69,728,165...69,730,519
Ensembl chr17:75,277,614...75,281,106 		JBrowse link
G LOC100991444 chromatin remodeling regulator CECR2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22154806) Ensembl
MGI
TreeGrafter		 PMID:22154806 GO_REF:0000107 GO_REF:0000118 NCBI chr22:795,525...987,645
Ensembl chr22:16,335,754...16,412,640 		JBrowse link
G NPM2 nucleophosmin/nucleoplasmin 2 involved_in IEA Ensembl
UniProt		 GO_REF:0000043 GO_REF:0000107 NCBI chr 8:21,268,873...21,281,684
Ensembl chr 8:18,208,934...18,221,577 		JBrowse link
G NPR2 natriuretic peptide receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:35,642,534...35,660,210
Ensembl chr 9:36,445,576...36,462,637 		JBrowse link
G OVGP1 oviductal glycoprotein 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:114,075,675...114,094,893
Ensembl chr 1:126,257,983...126,271,204 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G PLCZ1 phospholipase C zeta 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr12:18,678,349...18,733,048
Ensembl chr12:19,028,011...19,119,559 		JBrowse link
G PRND prion like protein doppel involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:4,749,111...4,755,647
Ensembl chr20:4,548,403...4,548,933 		JBrowse link
G RABL2B RAB, member of RAS oncogene family like 2B acts_upstream_of_or_within ISO (PMID:23055941) MGI PMID:23055941 NCBI chr22:31,007,409...31,023,281 JBrowse link
G RNASE10 ribonuclease A family member 10 (inactive) acts_upstream_of_or_within ISO (PMID:21084446) MGI PMID:21084446 NCBI chr14:1,378,780...1,385,894 JBrowse link
G SEC23IP SEC23 interacting protein acts_upstream_of_or_within ISO (PMID:21640725) MGI PMID:21640725 NCBI chr10:116,460,187...116,510,830
Ensembl chr10:119,876,408...119,928,064 		JBrowse link
G SLC22A16 solute carrier family 22 member 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:108,232,950...108,332,469
Ensembl chr 6:112,302,265...112,354,829 		JBrowse link
G SLIRP SRA stem-loop interacting RNA binding protein acts_upstream_of_or_within ISO (PMID:23976951) MGI PMID:23976951 NCBI chr14:58,262,126...58,271,829
Ensembl chr14:77,462,875...77,516,882 		JBrowse link
G SLMAP sarcolemma associated protein involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:57,688,669...57,864,355
Ensembl chr 3:59,108,247...59,280,713 		JBrowse link
G SMAD4 SMAD family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24739304) Ensembl
MGI		 PMID:24739304 GO_REF:0000107 NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359 		JBrowse link
G SNU13 small nuclear ribonucleoprotein 13 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9114055) Ensembl
MGI		 PMID:9114055 GO_REF:0000107 NCBI chr22:22,567,285...22,582,257
Ensembl chr22:40,653,338...40,669,706 		JBrowse link
G SPACA7 sperm acrosome associated 7 acts_upstream_of_or_within ISO (PMID:24307706) MGI PMID:24307706 NCBI chr13:93,505,639...93,564,287 JBrowse link
G SPAM1 sperm adhesion molecule 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12065596) UniProt
MGI		 PMID:12065596 GO_REF:0000117 NCBI chr 7:115,916,304...115,951,103
Ensembl chr 7:128,623,193...128,643,550 		JBrowse link
G TARBP2 TARBP2 subunit of RISC loading complex acts_upstream_of_or_within ISO (PMID:10369260) MGI PMID:10369260 NCBI chr12:35,246,937...35,253,378
Ensembl chr12:36,031,818...36,038,008 		JBrowse link
G TRPC3 transient receptor potential cation channel subfamily C member 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:114,079,395...114,153,014
Ensembl chr 4:125,217,086...125,289,014 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:96,414,498...96,551,670
Ensembl chr11:99,919,410...100,050,685 		JBrowse link
G TRPC7 transient receptor potential cation channel subfamily C member 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:131,604,175...131,756,944
Ensembl chr 5:137,743,638...137,896,107 		JBrowse link
G UMODL1 uromodulin like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23190605) Ensembl
MGI		 PMID:23190605 GO_REF:0000107 NCBI chr21:28,394,457...28,462,082
Ensembl chr21:41,717,761...41,783,172 		JBrowse link
G WDR48 WD repeat domain 48 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24001775) Ensembl
MGI		 PMID:24001775 GO_REF:0000107 NCBI chr 3:38,948,440...38,992,872
Ensembl chr 3:39,228,920...39,273,300 		JBrowse link
G WT1 WT1 transcription factor acts_upstream_of_or_within ISO (PMID:16418481) MGI PMID:16418481 NCBI chr11:32,349,807...32,398,494
Ensembl chr11:32,238,720...32,287,249 		JBrowse link
G ZP1 zona pellucida glycoprotein 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr11:56,129,347...56,142,385
Ensembl chr11:59,571,453...59,579,640 		JBrowse link
G ZP2 zona pellucida glycoprotein 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr16:17,193,632...17,210,667
Ensembl chr16:21,227,285...21,244,316 		JBrowse link
G ZP4 zona pellucida glycoprotein 4 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:213,435,888...213,444,439
Ensembl chr 1:218,428,967...218,442,383 		JBrowse link
acrosomal vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EQTN equatorin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19285662) InterPro
MGI
TreeGrafter		 PMID:19285662 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:27,109,424...27,144,789
Ensembl chr 9:27,737,861...27,750,736 		JBrowse link
G RAB3A RAB3A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768 		JBrowse link
G RIMS1 regulating synaptic membrane exocytosis 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422 		JBrowse link
G SYT6 synaptotagmin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:88,397,809...88,467,493
Ensembl chr 1:123,452,889...123,514,795 		JBrowse link
G UNC13B unc-13 homolog B involved_in ISO (PMID:22248876) UniProt PMID:22248876 NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894 		JBrowse link
G ZP4 zona pellucida glycoprotein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:213,435,888...213,444,439
Ensembl chr 1:218,428,967...218,442,383 		JBrowse link
acrosome matrix dispersal term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACR acrosin ISO RGD PMID:28859281 RGD:13464336 NCBI chr22:30,978,598...30,985,739
Ensembl chr22:50,085,719...50,092,869 		JBrowse link
acrosome reaction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD2 abhydrolase domain containing 2, acylglycerol lipase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:67,780,453...67,891,454
Ensembl chr15:86,987,070...87,095,818 		JBrowse link
G ACR acrosin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr22:30,978,598...30,985,739
Ensembl chr22:50,085,719...50,092,869 		JBrowse link
G ADCY3 adenylate cyclase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:24,812,729...24,913,539
Ensembl chr2A:24,908,108...25,009,163 		JBrowse link
G GARIN1B golgi associated RAB2 interactor 1B involved_in ISO (MGI:6814641|PMID:34714330) UniProt PMID:34714330 MGI:6814641 NCBI chr 7:120,649,308...120,684,035 JBrowse link
G GLRA1 glycine receptor alpha 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11076688) Ensembl
MGI		 PMID:11076688 GO_REF:0000107 NCBI chr 5:147,245,741...147,348,555
Ensembl chr 5:153,248,488...153,350,567 		JBrowse link
G GLRB glycine receptor beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11076688) Ensembl
MGI		 PMID:11076688 GO_REF:0000107 NCBI chr 4:149,422,654...149,518,669
Ensembl chr 4:161,236,610...161,333,035 		JBrowse link
G IFTAP intraflagellar transport associated protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30521625) Ensembl
MGI
TreeGrafter		 PMID:30521625 GO_REF:0000107 GO_REF:0000118 NCBI chr11:36,560,918...36,623,870
Ensembl chr11:36,433,630...36,496,483 		JBrowse link
G OVCH1 ovochymase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:56,807,004...56,868,758
Ensembl chr12:59,433,377...59,507,000 		JBrowse link
G PCSK4 proprotein convertase subtilisin/kexin type 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16371590) Ensembl
MGI		 PMID:16371590 GO_REF:0000107 Ensembl chr19:1,452,924...1,466,438 JBrowse link
G PLCD4 phospholipase C delta 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11340203) Ensembl
MGI		 PMID:11340203 GO_REF:0000107 NCBI chr2B:105,864,706...105,895,114
Ensembl chr2B:224,461,261...224,490,345 		JBrowse link
G PRND prion like protein doppel involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:4,749,111...4,755,647
Ensembl chr20:4,548,403...4,548,933 		JBrowse link
G PRSS21 serine protease 21 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:1,721,788...1,726,871 JBrowse link
G SPESP1 sperm equatorial segment protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20375058) InterPro
MGI
TreeGrafter		 PMID:20375058 GO_REF:0000002 GO_REF:0000118 NCBI chr15:47,775,405...47,902,786
Ensembl chr15:66,651,277...66,667,511 		JBrowse link
G ST14 ST14 transmembrane serine protease matriptase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:125,001,771...125,021,371
Ensembl chr11:128,888,124...128,913,559 		JBrowse link
G STX2 syntaxin 2 involved_in ISO (MGI:3584221|PMID:15774481) HGNC-UCL PMID:15774481 MGI:3584221 NCBI chr12:128,416,793...128,464,452
Ensembl chr12:132,614,793...132,650,559 		JBrowse link
G SYT6 synaptotagmin 6 involved_in ISO (MGI:3584221|PMID:15774481) HGNC-UCL PMID:15774481 MGI:3584221 NCBI chr 1:88,397,809...88,467,493
Ensembl chr 1:123,452,889...123,514,795 		JBrowse link
G SYT8 synaptotagmin 8 involved_in ISO (MGI:3584221|PMID:15774481) HGNC-UCL PMID:15774481 MGI:3584221 NCBI chr11:1,867,572...1,874,115
Ensembl chr11:1,902,554...1,910,084 		JBrowse link
G TMPRSS11E transmembrane serine protease 11E involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:55,559,762...55,609,900
Ensembl chr 4:61,953,256...62,015,111 		JBrowse link
G TMPRSS4 transmembrane serine protease 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:112,910,223...112,953,677
Ensembl chr11:116,843,287...116,884,767 		JBrowse link
G TNP2 transition protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11385107) TreeGrafter
MGI		 PMID:11385107 GO_REF:0000118 NCBI chr16:10,209,801...10,211,466
Ensembl chr16:11,431,822...11,433,087 		JBrowse link
G TRIM36 tripartite motif containing 36 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12917430) Ensembl
MGI
TreeGrafter		 PMID:12917430 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:110,481,462...110,540,949
Ensembl chr 5:116,279,587...116,335,848 		JBrowse link
activation of meiosis involved in egg activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAMK2B calcium/calmodulin dependent protein kinase II beta acts_upstream_of_or_within ISO (PMID:9882483) MGI PMID:9882483 NCBI chr 7:44,930,859...45,040,078
Ensembl chr 7:45,001,267...45,110,342 		JBrowse link
G NPR2 natriuretic peptide receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:35,642,534...35,660,210
Ensembl chr 9:36,445,576...36,462,637 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019 		JBrowse link
binding of sperm to zona pellucida term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACR acrosin acts_upstream_of_or_within ISO (PMID:15685642) MGI PMID:15685642 NCBI chr22:30,978,598...30,985,739
Ensembl chr22:50,085,719...50,092,869 		JBrowse link
G ADAM18 ADAM metallopeptidase domain 18 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr 8:36,283,808...36,435,537 JBrowse link
G ADAM2 ADAM metallopeptidase domain 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:38,939,413...39,034,142
Ensembl chr 8:36,448,201...36,542,784 		JBrowse link
G ADAM32 ADAM metallopeptidase domain 32 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:38,408,648...38,592,282
Ensembl chr 8:35,583,724...35,766,318 		JBrowse link
G ALDOA aldolase, fructose-bisphosphate A involved_in ISO (PMID:23355646) CAFA PMID:23355646
G ARSA arylsulfatase A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12080020) Ensembl
MGI		 PMID:12080020 GO_REF:0000107 NCBI chr22:30,868,812...30,871,970
Ensembl chr22:49,978,955...49,982,099 		JBrowse link
G ATP8B3 ATPase phospholipid transporting 8B3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14975727) Ensembl
MGI		 PMID:14975727 GO_REF:0000107 NCBI chr19:779,958...810,455
Ensembl chr19:1,761,992...1,791,878 		JBrowse link
G B4GALT1 beta-1,4-galactosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8089187), (PMID:9374408)
(PMID:9374408)		 Ensembl
MGI		 PMID:8089187 PMID:9374408 GO_REF:0000107 NCBI chr 9:32,889,124...32,945,759
Ensembl chr 9:33,691,733...33,754,192 		JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr12:67,113,221...67,128,159
Ensembl chr12:69,883,710...69,898,671 		JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr 1:131,652,058...131,679,802
Ensembl chr 1:135,481,427...135,508,983 		JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr2A:61,950,477...61,970,783
Ensembl chr2A:63,084,090...63,105,216 		JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 acts_upstream_of_or_within ISO (PMID:21880732) MGI PMID:21880732 NCBI chr 5:10,565,911...10,580,808
Ensembl chr 5:10,424,157...10,440,613 		JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A acts_upstream_of_or_within ISO (PMID:21880732) MGI PMID:21880732 NCBI chr 7:56,664,757...56,677,000
Ensembl chr 7:57,087,072...57,098,613 		JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr2A:73,287,026...73,305,792
Ensembl chr2A:74,775,781...74,794,515 		JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr21:15,489,698...15,507,292
Ensembl chr21:28,878,113...28,895,912 		JBrowse link
G CLGN calmegin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11784061), (PMID:9177349) Ensembl
MGI		 PMID:9177349 PMID:11784061 GO_REF:0000107 NCBI chr 4:132,756,193...132,794,805
Ensembl chr 4:144,060,656...144,099,419 		JBrowse link
G CRISP1 cysteine rich secretory protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21865554) TreeGrafter
MGI		 PMID:21865554 GO_REF:0000118 NCBI chr 6:49,404,220...49,452,287
Ensembl chr 6:50,665,204...50,712,092 		JBrowse link
G FETUB fetuin B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:183,675,258...183,687,754
Ensembl chr 3:192,142,702...192,154,920 		JBrowse link
G GLIPR1L1 GLIPR1 like 1 acts_upstream_of_or_within ISO (PMID:8260598) MGI PMID:8260598 NCBI chr12:72,861,071...72,896,693
Ensembl chr12:75,713,020...75,748,658 		JBrowse link
G H1-6 H1.6 linker histone, cluster member acts_upstream_of_or_within ISO (PMID:15685642) MGI PMID:15685642 NCBI chr 6:25,941,055...25,943,565
Ensembl chr 6:26,600,454...26,601,083 		JBrowse link
G HSPA1B heat shock protein family A (Hsp70) member 1B acts_upstream_of_or_within ISO (PMID:21880732) MGI PMID:21880732 NCBI chr 6:31,488,882...31,491,412 JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI		 PMID:21880732 GO_REF:0000107 NCBI chr 6:31,470,745...31,483,615
Ensembl chr 6:32,358,054...32,359,979 		JBrowse link
G LOC100968595 disintegrin and metalloproteinase domain-containing protein 1-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:109,473,137...109,476,766 JBrowse link
G LOC100984709 C4b-binding protein alpha chain involved_in
acts_upstream_of_or_within		 ISO (MGI:4942258|PMID:11417900)
(PMID:21880732), (PMID:7604284)		 UniProt
MGI		 PMID:7604284 PMID:11417900 PMID:21880732 MGI:4942258 NCBI chr 1:182,707,221...182,747,878
Ensembl chr 1:186,985,264...187,025,898 		JBrowse link
G LY6K lymphocyte antigen 6 family member K involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24501175) TreeGrafter
MGI		 PMID:24501175 GO_REF:0000118 NCBI chr 8:139,410,297...139,415,018
Ensembl chr 8:142,455,216...142,459,487 		JBrowse link
G PCSK4 proprotein convertase subtilisin/kexin type 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16371590) Ensembl
MGI		 PMID:16371590 GO_REF:0000107 Ensembl chr19:1,452,924...1,466,438 JBrowse link
G PRSS37 serine protease 37 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23553430) Ensembl
MGI		 PMID:23553430 GO_REF:0000107 NCBI chr 7:133,767,802...133,773,321
Ensembl chr 7:146,236,906...146,242,157 		JBrowse link
G PRSS55 serine protease 55 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:8,656,519...8,685,039 JBrowse link
G SMCP sperm mitochondria associated cysteine rich protein acts_upstream_of_or_within ISO (PMID:15685642) MGI PMID:15685642 NCBI chr 1:128,222,932...128,229,417
Ensembl chr 1:131,859,238...131,859,588 		JBrowse link
G SPA17 sperm autoantigenic protein 17 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:119,501,604...119,526,103
Ensembl chr11:123,416,725...123,437,818 		JBrowse link
G TCP1 t-complex 1 acts_upstream_of_or_within ISO (PMID:21880732) MGI PMID:21880732 NCBI chr 6:157,661,409...157,672,581
Ensembl chr 6:162,673,596...162,683,985 		JBrowse link
G TEX101 testis expressed 101 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:40,356,333...40,359,285
Ensembl chr19:48,947,871...48,969,317 		JBrowse link
G TMPRSS12 transmembrane serine protease 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:32529245) Ensembl
MGI		 PMID:32529245 GO_REF:0000107 NCBI chr12:37,865,660...37,908,657
Ensembl chr12:38,768,072...38,810,372 		JBrowse link
G TNP2 transition protein 2 acts_upstream_of_or_within ISO (PMID:15685642) MGI PMID:15685642 NCBI chr16:10,209,801...10,211,466
Ensembl chr16:11,431,822...11,433,087 		JBrowse link
G UBAP2L ubiquitin associated protein 2 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:129,575,115...129,626,565
Ensembl chr 1:133,189,194...133,240,090 		JBrowse link
G VDAC2 voltage dependent anion channel 2 involved_in ISO (PMID:23355646) CAFA PMID:23355646 NCBI chr10:71,739,395...71,763,835 JBrowse link
G VDAC2 voltage dependent anion channel 2 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr10:74,403,611...74,426,423 JBrowse link
G ZAN zonadhesin acts_upstream_of_or_within ISO (PMID:7592795) MGI PMID:7592795 NCBI chr 7:92,763,696...92,819,419 JBrowse link
G ZP1 zona pellucida glycoprotein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:56,129,347...56,142,385
Ensembl chr11:59,571,453...59,579,640 		JBrowse link
G ZP2 zona pellucida glycoprotein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11739644) Ensembl
MGI
TreeGrafter		 PMID:11739644 GO_REF:0000107 GO_REF:0000118 NCBI chr16:17,193,632...17,210,667
Ensembl chr16:21,227,285...21,244,316 		JBrowse link
G ZP3 zona pellucida glycoprotein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11739644)
(PMID:9374408)		 UniProt
MGI
Ensembl		 PMID:9374408 PMID:11739644 GO_REF:0000104 GO_REF:0000107 NCBI chr 7:67,574,932...67,592,757
Ensembl chr 7:82,844,162...82,891,655 		JBrowse link
G ZP4 zona pellucida glycoprotein 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:213,435,888...213,444,439
Ensembl chr 1:218,428,967...218,442,383 		JBrowse link
G ZPBP zona pellucida binding protein involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) InterPro
MGI
TreeGrafter		 PMID:21880732 GO_REF:0000002 GO_REF:0000118 NCBI chr 7:50,576,485...50,735,411
Ensembl chr 7:50,826,058...50,981,644 		JBrowse link
G ZPBP2 zona pellucida binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21880732) Ensembl
MGI
TreeGrafter
InterPro		 PMID:21880732 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr17:17,410,278...17,420,458
Ensembl chr17:17,630,126...17,639,771 		JBrowse link
cortical granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYH9 myosin heavy chain 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618 		JBrowse link
G NLRP5 NLR family pyrin domain containing 5 involved_in ISO (MGI:6323780|PMID:31118423) UniProt PMID:31118423 MGI:6323780 NCBI chr19:53,021,034...53,083,590
Ensembl chr19:61,818,345...61,879,538 		JBrowse link
egg activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAST calpastatin ISO RGD PMID:16388007 RGD:5683870 NCBI chr 5:91,972,572...92,084,657
Ensembl chr 5:97,527,071...97,636,650 		JBrowse link
G PLCZ1 phospholipase C zeta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12117804) Ensembl
MGI		 PMID:12117804 GO_REF:0000107 NCBI chr12:18,678,349...18,733,048
Ensembl chr12:19,028,011...19,119,559 		JBrowse link
female pronucleus assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G WEE2 WEE2 oocyte meiosis inhibiting kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:133,635,359...133,663,153
Ensembl chr 7:146,110,121...146,132,872 		JBrowse link
fusion of sperm to egg plasma membrane involved in single fertilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C18H16orf92 chromosome 18 C16orf92 homolog involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 Ensembl chr16:30,398,743...30,399,615 JBrowse link
G CATSPER1 cation channel sperm associated 1 acts_upstream_of_or_within ISO (PMID:11595941) MGI PMID:11595941 NCBI chr11:61,381,175...61,391,455
Ensembl chr11:64,707,912...64,717,689 		JBrowse link
G CD9 CD9 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,327,783...6,366,083
Ensembl chr12:6,245,348...6,283,385 		JBrowse link
G DCST1 DC-STAMP domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,381,851...130,398,975
Ensembl chr 1:133,991,485...134,008,614 		JBrowse link
G DCST2 DC-STAMP domain containing 2 involved_in ISO (MGI:6694748|PMID:33871360) UniProt PMID:33871360 MGI:6694748 NCBI chr 1:130,366,692...130,382,001 JBrowse link
G EQTN equatorin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9674989) InterPro
MGI
TreeGrafter		 PMID:9674989 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:27,109,424...27,144,789
Ensembl chr 9:27,737,861...27,750,736 		JBrowse link
G FOLR2 folate receptor beta involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:67,295,305...67,300,463
Ensembl chr11:70,518,931...70,524,088 		JBrowse link
G FOLR3 folate receptor gamma involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:67,215,877...67,220,088
Ensembl chr11:70,439,298...70,443,479 		JBrowse link
G FREY1 Frey regulator of sperm-oocyte fusion 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:45,860,688...45,863,703
Ensembl chr11:46,352,806...46,353,867 		JBrowse link
G GLIPR1L1 GLIPR1 like 1 involved_in ISO (MGI:6436237|PMID:31672133), (PMID:31672133) UniProt PMID:31672133 MGI:6436237 NCBI chr12:72,861,071...72,896,693
Ensembl chr12:75,713,020...75,748,658 		JBrowse link
G ITGA3 integrin subunit alpha 3 NOT|acts_upstream_of_or_within ISO (PMID:12591243) MGI PMID:12591243 NCBI chr17:44,145,974...44,181,343
Ensembl chr17:49,019,892...49,055,245 		JBrowse link
G IZUMO1 izumo sperm-oocyte fusion 1 involved_in IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr19:45,740,372...45,747,177
Ensembl chr19:54,330,545...54,337,533 		JBrowse link
G IZUMO1R IZUMO1 receptor, JUNO involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:89,318,370...89,322,004
Ensembl chr11:92,805,614...92,807,669 		JBrowse link
G LLCFC1 LLLL and CFNLAS motif containing 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 7:134,928,345...134,940,750
Ensembl chr 7:147,421,354...147,422,719 		JBrowse link
G LOC100976701 lysozyme-like protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:29,442,419...29,464,512
Ensembl chr10:29,797,709...29,820,438 		JBrowse link
G LOC100979617 lysozyme-like protein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:30,756,509...30,774,594
Ensembl chr10:31,109,496...31,127,131 		JBrowse link
G LOC100994139 folate receptor alpha involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:67,268,721...67,275,498
Ensembl chr11:70,492,039...70,498,665 		JBrowse link
G LYZL4 lysozyme like 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 3:42,302,237...42,378,700
Ensembl chr 3:42,565,535...42,579,033 		JBrowse link
G LYZL6 lysozyme like 6 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:20,852,333...20,861,505
Ensembl chr17:21,147,928...21,157,112 		JBrowse link
G SPACA3 sperm acrosome associated 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:23,789,295...23,810,711
Ensembl chr17:24,081,007...24,086,998 		JBrowse link
G SPACA5 sperm acrosome associated 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:40,435,554...40,441,190 JBrowse link
G SPACA6 sperm acrosome associated 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24275887) InterPro
MGI
TreeGrafter		 PMID:24275887 GO_REF:0000002 GO_REF:0000118 NCBI chr19:48,632,681...48,656,124
Ensembl chr19:57,517,865...57,529,817 		JBrowse link
G SPAM1 sperm adhesion molecule 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:115,916,304...115,951,103
Ensembl chr 7:128,623,193...128,643,550 		JBrowse link
G SPATA46 spermatogenesis associated 46 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:137,785,032...137,790,863
Ensembl chr 1:141,585,288...141,588,306 		JBrowse link
G SPESP1 sperm equatorial segment protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20375058) InterPro
MGI
TreeGrafter		 PMID:20375058 GO_REF:0000002 GO_REF:0000118 NCBI chr15:47,775,405...47,902,786
Ensembl chr15:66,651,277...66,667,511 		JBrowse link
G SPPL2C signal peptide peptidase like 2C involved_in ISO (PMID:35960805) UniProt PMID:35960805 NCBI chr17:11,323,494...11,325,924
Ensembl chr17:11,637,880...11,639,934 		JBrowse link
G TMEM95 transmembrane protein 95 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr17:7,389,244...7,391,773
Ensembl chr17:7,375,571...7,377,086 		JBrowse link
G TPST2 tyrosylprotein sulfotransferase 2 acts_upstream_of_or_within ISO (PMID:21339297) MGI PMID:21339297 NCBI chr22:7,587,446...7,651,645
Ensembl chr22:25,309,254...25,334,638 		JBrowse link
negative regulation of acrosome reaction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPINK13 serine peptidase inhibitor Kazal type 13 involved_in ISO PMID:23430248 UniProt PMID:23430248 RGD:8553255 NCBI chr 5:143,692,686...143,713,035
Ensembl chr 5:149,702,870...149,721,406 		JBrowse link
negative regulation of binding of sperm to zona pellucida term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASTL astacin like metalloendopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:103,176,662...103,192,542
Ensembl chr2A:97,049,184...97,063,747 		JBrowse link
G OVGP1 oviductal glycoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19808884) Ensembl
MGI		 PMID:19808884 GO_REF:0000107 NCBI chr 1:114,075,675...114,094,893
Ensembl chr 1:126,257,983...126,271,204 		JBrowse link
G ZP3 zona pellucida glycoprotein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:67,574,932...67,592,757
Ensembl chr 7:82,844,162...82,891,655 		JBrowse link
G ZP4 zona pellucida glycoprotein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:213,435,888...213,444,439
Ensembl chr 1:218,428,967...218,442,383 		JBrowse link
penetration of cumulus oophorus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PITHD1 PITH domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31915251) Ensembl
MGI		 PMID:31915251 GO_REF:0000107 NCBI chr 1:22,970,081...22,979,841
Ensembl chr 1:23,954,980...23,964,085 		JBrowse link
penetration of zona pellucida term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACR acrosin acts_upstream_of_or_within ISO (PMID:15051954)
(PMID:9041140)
(PMID:7989357)		 RGD
MGI		 PMID:7989357 PMID:9041140 PMID:15051954 PMID:28859281 RGD:13464336 NCBI chr22:30,978,598...30,985,739
Ensembl chr22:50,085,719...50,092,869 		JBrowse link
G B4GALT1 beta-1,4-galactosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9374408) Ensembl
MGI		 PMID:9374408 GO_REF:0000107 NCBI chr 9:32,889,124...32,945,759
Ensembl chr 9:33,691,733...33,754,192 		JBrowse link
G DKKL1 dickkopf like acrosomal protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,375,301...46,389,822
Ensembl chr19:55,301,955...55,313,690 		JBrowse link
G HEXB hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8269854) Ensembl
MGI		 PMID:8269854 GO_REF:0000107 NCBI chr 5:40,589,448...40,625,176
Ensembl chr 5:41,199,681...41,232,693 		JBrowse link
G HYAL3 hyaluronidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:50,221,428...50,228,062
Ensembl chr 3:51,456,173...51,462,815 		JBrowse link
G PITHD1 PITH domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:31915251) Ensembl
MGI		 PMID:31915251 GO_REF:0000107 NCBI chr 1:22,970,081...22,979,841
Ensembl chr 1:23,954,980...23,964,085 		JBrowse link
G PPP3CC protein phosphatase 3 catalytic subunit gamma acts_upstream_of_or_within ISO (PMID:26429887) MGI PMID:26429887 NCBI chr 8:21,690,598...21,791,335
Ensembl chr 8:18,629,261...18,729,995 		JBrowse link
G PPP3R2 protein phosphatase 3 regulatory subunit B, beta acts_upstream_of_or_within ISO (PMID:26429887) MGI PMID:26429887 NCBI chr 9:72,796,099...72,799,499 JBrowse link
G SMCP sperm mitochondria associated cysteine rich protein acts_upstream_of_or_within ISO (PMID:15051954)
(PMID:11940662)		 MGI PMID:11940662 PMID:15051954 NCBI chr 1:128,222,932...128,229,417
Ensembl chr 1:131,859,238...131,859,588 		JBrowse link
G TBXT T-box transcription factor T involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:7883069) Ensembl
MGI		 PMID:7883069 GO_REF:0000107 NCBI chr 6:164,112,117...164,122,253
Ensembl chr 6:169,095,723...169,106,595 		JBrowse link
G TNP2 transition protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11385107) TreeGrafter
MGI		 PMID:11385107 GO_REF:0000118 NCBI chr16:10,209,801...10,211,466
Ensembl chr16:11,431,822...11,433,087 		JBrowse link
positive regulation of acrosomal vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HYAL3 hyaluronidase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:50,221,428...50,228,062
Ensembl chr 3:51,456,173...51,462,815 		JBrowse link
G ZP3 zona pellucida glycoprotein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:67,574,932...67,592,757
Ensembl chr 7:82,844,162...82,891,655 		JBrowse link
positive regulation of acrosome reaction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:1,195,364...1,222,917 JBrowse link
G CCDC87 coiled-coil domain containing 87 involved_in ISO (MGI:6201938|PMID:29733332) UniProt PMID:29733332 MGI:6201938 NCBI chr11:61,946,954...61,949,840 JBrowse link
G FAM170B family with sequence similarity 170 member B involved_in ISO (MGI:5705205|PMID:26179146) UniProt PMID:26179146 MGI:5705205 NCBI chr10:45,110,158...45,113,019 JBrowse link
G GLRA1 glycine receptor alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:147,245,741...147,348,555
Ensembl chr 5:153,248,488...153,350,567 		JBrowse link
G IQCF1 IQ motif containing F1 involved_in ISO (MGI:5708001|PMID:25380116) UniProt PMID:25380116 MGI:5708001 NCBI chr 3:51,836,683...51,847,503
Ensembl chr 3:53,068,302...53,076,490 		JBrowse link
G LOC100990946 group 10 secretory phospholipase A2 involved_in ISO (MGI:4459353|PMID:20424324) UniProt PMID:20424324 MGI:4459353 NCBI chr16:13,600,152...13,622,629 JBrowse link
G PLB1 phospholipase B1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23943622) Ensembl
MGI		 PMID:23943622 GO_REF:0000107 NCBI chr2A:28,502,449...28,650,348
Ensembl chr2A:28,584,636...28,730,640 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019 		JBrowse link
G PRSS37 serine protease 37 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:133,767,802...133,773,321
Ensembl chr 7:146,236,906...146,242,157 		JBrowse link
G RLN2 relaxin 2 involved_in ISO (PMID:16926527) CACAO PMID:16926527 NCBI chr 9:5,138,882...5,167,037
Ensembl chr 9:5,324,368...5,329,081 		JBrowse link
G ZP3 zona pellucida glycoprotein 3 involved_in IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr 7:67,574,932...67,592,757
Ensembl chr 7:82,844,162...82,891,655 		JBrowse link
G ZP4 zona pellucida glycoprotein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:213,435,888...213,444,439
Ensembl chr 1:218,428,967...218,442,383 		JBrowse link
positive regulation of cytosolic calcium ion concentration involved in egg activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLCZ1 phospholipase C zeta 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:18,678,349...18,733,048
Ensembl chr12:19,028,011...19,119,559 		JBrowse link
prevention of polyspermy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASTL astacin like metalloendopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:103,176,662...103,192,542
Ensembl chr2A:97,049,184...97,063,747 		JBrowse link
G PLAT plasminogen activator, tissue type involved_in ISO PMID:1515147 UniProt PMID:1515147 RGD:42721992 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G TPST2 tyrosylprotein sulfotransferase 2 acts_upstream_of_or_within ISO (PMID:21339297) MGI PMID:21339297 NCBI chr22:7,587,446...7,651,645
Ensembl chr22:25,309,254...25,334,638 		JBrowse link
G ZP1 zona pellucida glycoprotein 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:56,129,347...56,142,385
Ensembl chr11:59,571,453...59,579,640 		JBrowse link
G ZP2 zona pellucida glycoprotein 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:17,193,632...17,210,667
Ensembl chr16:21,227,285...21,244,316 		JBrowse link
G ZP4 zona pellucida glycoprotein 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:213,435,888...213,444,439
Ensembl chr 1:218,428,967...218,442,383 		JBrowse link
protein localization involved in acrosome reaction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLIPR1L1 GLIPR1 like 1 involved_in ISO (PMID:31672133) UniProt PMID:31672133 NCBI chr12:72,861,071...72,896,693
Ensembl chr12:75,713,020...75,748,658 		JBrowse link
regulation of acrosomal vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STXBP1 syntaxin binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152 		JBrowse link
regulation of acrosome reaction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B4GALT1 beta-1,4-galactosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9374408) Ensembl
MGI		 PMID:9374408 GO_REF:0000107 NCBI chr 9:32,889,124...32,945,759
Ensembl chr 9:33,691,733...33,754,192 		JBrowse link
G CRISP1 cysteine rich secretory protein 1 acts_upstream_of_or_within ISO (PMID:21482758) MGI PMID:21482758 NCBI chr 6:49,404,220...49,452,287
Ensembl chr 6:50,665,204...50,712,092 		JBrowse link
G HVCN1 hydrogen voltage gated channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:108,217,516...108,258,210
Ensembl chr12:111,591,050...111,645,632 		JBrowse link
G PKDREJ polycystin family receptor for egg jelly acts_upstream_of_or_within ISO (PMID:18562295) MGI PMID:18562295 Ensembl chr22:45,321,867...45,333,429 JBrowse link
G SERPINA10 serpin family A member 10 NOT|involved_in ISO (PMID:11751269) UniProt PMID:11751269 NCBI chr14:74,914,680...74,927,325
Ensembl chr14:94,248,362...94,257,835 		JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 acts_upstream_of_or_within ISO (PMID:22228629) MGI PMID:22228629 NCBI chr 5:143,273,137...143,287,745 JBrowse link
G ZP2 zona pellucida glycoprotein 2 NOT|involved_in ISO (PMID:11751269), (PMID:20394732) UniProt PMID:11751269 PMID:20394732 NCBI chr16:17,193,632...17,210,667
Ensembl chr16:21,227,285...21,244,316 		JBrowse link
regulation of binding of sperm to zona pellucida term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAEP progestagen associated endometrial protein involved_in ISO (PMID:17192260) UniProt PMID:17192260 NCBI chr 9:106,669,550...106,681,918 JBrowse link
G ZAN zonadhesin acts_upstream_of_or_within ISO (PMID:20529856) MGI PMID:20529856 NCBI chr 7:92,763,696...92,819,419 JBrowse link
sperm entry term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UBE3A ubiquitin protein ligase E3A acts_upstream_of_or_within ISO (PMID:11756548) MGI PMID:11756548 NCBI chr15:4,494,029...4,595,415
Ensembl chr15:22,747,075...22,825,459 		JBrowse link
sperm-egg recognition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD9 CD9 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,327,783...6,366,083
Ensembl chr12:6,245,348...6,283,385 		JBrowse link
G DCST1 DC-STAMP domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,381,851...130,398,975
Ensembl chr 1:133,991,485...134,008,614 		JBrowse link
G DCST2 DC-STAMP domain containing 2 involved_in ISO (MGI:6694748|PMID:33871360) UniProt PMID:33871360 MGI:6694748 NCBI chr 1:130,366,692...130,382,001 JBrowse link
G FOLR2 folate receptor beta involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:67,295,305...67,300,463
Ensembl chr11:70,518,931...70,524,088 		JBrowse link
G FOLR3 folate receptor gamma involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:67,215,877...67,220,088
Ensembl chr11:70,439,298...70,443,479 		JBrowse link
G FREY1 Frey regulator of sperm-oocyte fusion 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:45,860,688...45,863,703
Ensembl chr11:46,352,806...46,353,867 		JBrowse link
G IZUMO1 izumo sperm-oocyte fusion 1 involved_in IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr19:45,740,372...45,747,177
Ensembl chr19:54,330,545...54,337,533 		JBrowse link
G IZUMO1R IZUMO1 receptor, JUNO involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:89,318,370...89,322,004
Ensembl chr11:92,805,614...92,807,669 		JBrowse link
G LOC100994139 folate receptor alpha involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:67,268,721...67,275,498
Ensembl chr11:70,492,039...70,498,665 		JBrowse link
G SPACA3 sperm acrosome associated 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15982649) Ensembl
MGI		 PMID:15982649 GO_REF:0000107 NCBI chr17:23,789,295...23,810,711
Ensembl chr17:24,081,007...24,086,998 		JBrowse link
G SPACA4 sperm acrosome associated 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:45,607,816...45,609,081
Ensembl chr19:54,199,847...54,200,221 		JBrowse link
G SPESP1 sperm equatorial segment protein 1 involved_in ISO (MGI:5643961|PMID:25761597) UniProt PMID:25761597 MGI:5643961 NCBI chr15:47,775,405...47,902,786
Ensembl chr15:66,651,277...66,667,511 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16447
    reproductive process 1692
      fertilization 220
        single fertilization 170
          acrosome reaction + 47
          centrosomal and pronuclear rotation 0
          egg activation + 13
          female pronucleus assembly 1
          fusion of sperm to egg plasma membrane involved in single fertilization + 28
          male pronucleus assembly + 0
          penetration of cumulus oophorus 1
          penetration of zona pellucida 11
          pronuclear envelope synthesis + 0
          pronuclear fusion 0
          pronuclear migration 0
          respiratory burst at fertilization 0
          sperm aster formation 0
          sperm entry 1
          sperm plasma membrane disassembly 0
          sperm-egg recognition + 59
Path 2
Term Annotations click to browse term
  biological_process 16447
    reproductive process 1692
      sexual reproduction 1088
        fertilization 220
          single fertilization 170
            acrosome reaction + 47
            centrosomal and pronuclear rotation 0
            egg activation + 13
            female pronucleus assembly 1
            fusion of sperm to egg plasma membrane involved in single fertilization + 28
            male pronucleus assembly + 0
            penetration of cumulus oophorus 1
            penetration of zona pellucida 11
            pronuclear envelope synthesis + 0
            pronuclear fusion 0
            pronuclear migration 0
            respiratory burst at fertilization 0
            sperm aster formation 0
            sperm entry 1
            sperm plasma membrane disassembly 0
            sperm-egg recognition + 59
paths to the root