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ONTOLOGY REPORT - ANNOTATIONS


Term:egg activation
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Accession:GO:0007343 term browser browse the term
Definition:The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.
Synonyms:xref: Wikipedia:Egg_activation



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egg activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cast calpastatin IDA RGD PMID:16388007 RGD:5683870 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Plcz1 phospholipase C, zeta 1 involved_in
acts_upstream_of_or_within
ISO
ISS
(PMID:26721930)
(MGI:2182519|PMID:12117804)
GO_REF:0000024
RGD
UniProt
PMID:12117804 PMID:26721930 GO_REF:0000024 MGI:2182519 NCBI chr 4:172,873,110...172,929,191
Ensembl chr 4:172,873,112...172,928,358
JBrowse link
activation of meiosis involved in egg activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of_or_within ISO (MGI:1327475|PMID:9882483) RGD PMID:9882483 MGI:1327475 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Npr2 natriuretic peptide receptor 2 involved_in ISO MGI:1856702|MGI:4358115|MGI:5911053 (MGI:5442436|PMID:23065701), (MGI:5449332|PMID:22987720), (MGI:5749298|PMID:26522847) RGD PMID:22987720 PMID:23065701 PMID:26522847 MGI:5442436 MGI:5449332 MGI:5749298 NCBI chr 5:57,883,171...57,901,590
Ensembl chr 5:57,883,171...57,901,580
JBrowse link
G Plcb1 phospholipase C beta 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(MGI:4942248|PMID:14499343)
BHF-UCL
Ensembl
RGD
PMID:14499343 GO_REF:0000024 GO_REF:0000107 MGI:4942248 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
cortical granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh9 myosin, heavy chain 9 involved_in ISO
IEA
ISS
(MGI:6323780|PMID:31118423)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:31118423 GO_REF:0000024 GO_REF:0000107 MGI:6323780 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
G Nlrp5 NLR family, pyrin domain containing 5 involved_in ISO (MGI:6323780|PMID:31118423) RGD PMID:31118423 MGI:6323780 NCBI chr 1:67,778,037...67,810,946
Ensembl chr 1:67,777,948...68,023,736
JBrowse link
positive regulation of cytosolic calcium ion concentration involved in egg activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcz1 phospholipase C, zeta 1 involved_in IBA
ISO
IDA
PMID:21873635
(MGI:6120337|PMID:18322275)
(PMID:18322275), (PMID:26116451)
RGD PMID:18322275 PMID:26116451 PMID:21873635 PMID:18322275 MGI:6120337, RGD:13792537, RGD:13507301 NCBI chr 4:172,873,110...172,929,191
Ensembl chr 4:172,873,112...172,928,358
JBrowse link
prevention of polyspermy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam24 ADAM metallopeptidase domain 24 acts_upstream_of_or_within ISO MGI:4437125 (MGI:4429778|PMID:19670298) RGD PMID:19670298 MGI:4429778 NCBI chr16:51,578,278...51,584,342
Ensembl chr16:51,578,277...51,584,312
JBrowse link
G Astl astacin like metalloendopeptidase involved_in ISO (MGI:5427546|PMID:22472438) RGD PMID:22472438 MGI:5427546 NCBI chr 3:114,563,135...114,580,295
Ensembl chr 3:114,563,135...114,578,868
JBrowse link
G Plat plasminogen activator, tissue type involved_in IDA PMID:1515147 UniProt PMID:1515147 RGD:42721992 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Tpst2 tyrosylprotein sulfotransferase 2 acts_upstream_of_or_within ISO MGI:3512111 (MGI:4948779|PMID:21339297) RGD PMID:21339297 MGI:4948779 NCBI chr12:44,321,875...44,363,892
Ensembl chr12:44,321,875...44,362,329
JBrowse link
G Zp1 zona pellucida glycoprotein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:207,560,881...207,567,261
Ensembl chr 1:207,560,881...207,567,261
JBrowse link
G Zp2 zona pellucida glycoprotein 2 involved_in IEA
IBA
ISO
ISS
GO_REF:0000107
PMID:21873635
(MGI:5427546|PMID:22472438)
Ensembl
RGD
PMID:22472438 PMID:21873635 PMID:22472438 GO_REF:0000107 MGI:5427546, RGD:13792537, RGD:8554097 NCBI chr 1:174,513,507...174,525,288
Ensembl chr 1:174,513,511...174,525,288
JBrowse link
G Zp4 zona pellucida glycoprotein 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:59,005,649...59,012,202
Ensembl chr17:59,005,649...59,012,202
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    reproductive process 1779
      egg activation 14
        activation of meiosis involved in egg activation 3
        positive regulation of cytosolic calcium ion concentration involved in egg activation + 1
        prevention of polyspermy + 9
Path 2
Term Annotations click to browse term
  biological_process 19748
    reproduction 1789
      reproductive process 1779
        fertilization 211
          single fertilization 162
            egg activation 14
              activation of meiosis involved in egg activation 3
              positive regulation of cytosolic calcium ion concentration involved in egg activation + 1
              prevention of polyspermy + 9
paths to the root