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Gene: Plcz1 (phospholipase C, zeta 1) Rattus norvegicus
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Symbol: Plcz1
Name: phospholipase C, zeta 1
Description: Predicted to have phosphatidylinositol phosphate binding activity and phosphatidylinositol phospholipase C activity. Involved in positive regulation of cytosolic calcium ion concentration involved in egg activation. Localizes to the cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 17. Orthologous to human PLCZ1 (phospholipase C zeta 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH bisphenol A; silicon dioxide (ortholog); simazine (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1; phosphoinositide phospholipase C-zeta-1; phospholipase C-zeta-1; PLC-zeta-1
Orthologs:
Homo sapiens (human) : PLCZ1 (phospholipase C zeta 1)  HGNC  Alliance
Mus musculus (house mouse) : Plcz1 (phospholipase C, zeta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plcz1 (phospholipase C zeta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLCZ1 (phospholipase C zeta 1)
Canis lupus familiaris (dog) : PLCZ1 (phospholipase C zeta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plcz1 (phospholipase C zeta 1)
Sus scrofa (pig) : PLCZ1 (phospholipase C zeta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04174,125,072 - 174,181,524 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04238,378,233 - 238,434,471 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44177,096,157 - 177,162,109 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14177,341,281 - 177,407,233 (-)NCBI
Celera4161,424,191 - 161,480,156 (-)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Plcz1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359567
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.