Plcz1 (phospholipase C, zeta 1) - Rat Genome Database

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Gene: Plcz1 (phospholipase C, zeta 1) Rattus norvegicus
Analyze
Symbol: Plcz1
Name: phospholipase C, zeta 1
RGD ID: 1359567
Description: Predicted to enable phosphatidylinositol phosphate binding activity and phosphatidylinositol phospholipase C activity. Involved in positive regulation of cytosolic calcium ion concentration involved in egg activation. Located in cytoplasm. Human ortholog(s) of this gene implicated in spermatogenic failure 17. Orthologous to human PLCZ1 (phospholipase C zeta 1); PARTICIPATES IN calcium/calcium-mediated signaling pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1; phosphoinositide phospholipase C-zeta-1; phospholipase C-zeta-1; PLC-zeta-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84174,604,281 - 174,660,368 (-)NCBIGRCr8
mRatBN7.24172,873,110 - 172,929,191 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4172,873,112 - 172,928,358 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4179,168,219 - 179,223,363 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04174,952,394 - 175,007,537 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04173,572,940 - 173,628,084 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04174,125,072 - 174,181,524 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4174,125,178 - 174,180,729 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04238,378,233 - 238,434,471 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44177,096,157 - 177,162,109 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14177,341,281 - 177,407,233 (-)NCBI
Celera4161,424,191 - 161,480,156 (-)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Difference in Ca2+ oscillation-inducing activity and nuclear translocation ability of PLCZ1, an egg-activating sperm factor candidate, between mouse, rat, human, and medaka fish. Ito M, etal., Biol Reprod. 2008 Jun;78(6):1081-90. doi: 10.1095/biolreprod.108.067801. Epub 2008 Mar 5.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12117804   PMID:14701816   PMID:26116451   PMID:26721930   PMID:28270562  


Genomics

Comparative Map Data
Plcz1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84174,604,281 - 174,660,368 (-)NCBIGRCr8
mRatBN7.24172,873,110 - 172,929,191 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4172,873,112 - 172,928,358 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4179,168,219 - 179,223,363 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04174,952,394 - 175,007,537 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04173,572,940 - 173,628,084 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04174,125,072 - 174,181,524 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4174,125,178 - 174,180,729 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04238,378,233 - 238,434,471 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44177,096,157 - 177,162,109 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14177,341,281 - 177,407,233 (-)NCBI
Celera4161,424,191 - 161,480,156 (-)NCBICelera
Cytogenetic Map4q44NCBI
PLCZ1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381218,645,609 - 18,738,012 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1218,683,169 - 18,738,100 (-)EnsemblGRCh38hg38GRCh38
GRCh371218,836,114 - 18,890,946 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361218,727,383 - 18,782,185 (-)NCBINCBI36Build 36hg18NCBI36
Build 341218,727,382 - 18,782,185NCBI
Celera1223,981,631 - 24,036,436 (-)NCBICelera
Cytogenetic Map12p12.3NCBI
HuRef1218,604,503 - 18,659,985 (-)NCBIHuRef
CHM1_11218,801,167 - 18,856,044 (-)NCBICHM1_1
T2T-CHM13v2.01218,521,542 - 18,613,927 (-)NCBIT2T-CHM13v2.0
Plcz1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396139,933,118 - 139,987,188 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6139,935,399 - 139,987,183 (-)EnsemblGRCm39 Ensembl
GRCm386139,987,396 - 140,041,488 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6139,989,673 - 140,041,457 (-)EnsemblGRCm38mm10GRCm38
MGSCv376139,938,243 - 139,989,938 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366139,952,128 - 140,003,823 (-)NCBIMGSCv36mm8
Celera6143,053,490 - 143,105,163 (-)NCBICelera
Cytogenetic Map6G2NCBI
cM Map669.77NCBI
Plcz1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541314,791,703 - 14,845,792 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541314,791,750 - 14,846,327 (-)NCBIChiLan1.0ChiLan1.0
PLCZ1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21024,085,594 - 24,175,573 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11224,082,355 - 24,172,334 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01218,678,349 - 18,733,048 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11219,064,945 - 19,119,559 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1219,028,011 - 19,119,559 (-)Ensemblpanpan1.1panPan2
PLCZ1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12728,363,207 - 28,446,377 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2728,362,999 - 28,419,270 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2718,005,284 - 18,088,033 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02728,694,850 - 28,777,322 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2728,695,423 - 28,750,192 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12728,541,596 - 28,624,378 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02728,534,157 - 28,616,711 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02717,713,109 - 17,795,922 (-)NCBIUU_Cfam_GSD_1.0
Plcz1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494589,598,377 - 89,650,717 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365487,522,926 - 7,573,540 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365487,522,902 - 7,573,540 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCZ1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl554,408,296 - 54,452,417 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1554,257,709 - 54,452,557 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2557,680,677 - 57,724,905 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCZ1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11118,534,672 - 18,587,756 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1118,534,734 - 18,586,041 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606916,626,501 - 16,679,788 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcz1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475219,803,995 - 19,879,605 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475219,726,686 - 19,883,279 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plcz1
457 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:12
Count of miRNA genes:12
Interacting mature miRNAs:12
Transcripts:ENSRNOT00000011376
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4157710145182687754Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7
Low 1 1 1 1 1
Below cutoff 1 6 1 6 1 3 3 27 2 16 5 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039108052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010065686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC096930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY885259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000011376   ⟹   ENSRNOP00000011376
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4172,873,112 - 172,928,358 (-)Ensembl
Rnor_6.0 Ensembl4174,125,178 - 174,180,729 (-)Ensembl
RefSeq Acc Id: NM_001012234   ⟹   NP_001012234
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,290 (-)NCBI
mRatBN7.24172,873,114 - 172,929,117 (-)NCBI
Rnor_6.04174,125,178 - 174,180,729 (-)NCBI
Rnor_5.04238,378,233 - 238,434,471 (-)NCBI
RGSC_v3.44177,096,157 - 177,162,109 (-)RGD
Celera4161,424,191 - 161,480,156 (-)RGD
Sequence:
RefSeq Acc Id: XM_006237600   ⟹   XP_006237662
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,327 (-)NCBI
mRatBN7.24172,873,110 - 172,929,145 (-)NCBI
Rnor_6.04174,125,072 - 174,181,519 (-)NCBI
Rnor_5.04238,378,233 - 238,434,471 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592771   ⟹   XP_017448260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,658,695 (-)NCBI
mRatBN7.24172,873,110 - 172,927,522 (-)NCBI
Rnor_6.04174,125,072 - 174,179,856 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039108046   ⟹   XP_038963974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,658,695 (-)NCBI
mRatBN7.24172,873,110 - 172,927,524 (-)NCBI
RefSeq Acc Id: XM_039108047   ⟹   XP_038963975
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,327 (-)NCBI
mRatBN7.24172,873,110 - 172,929,145 (-)NCBI
RefSeq Acc Id: XM_039108048   ⟹   XP_038963976
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,350 (-)NCBI
mRatBN7.24172,873,110 - 172,929,162 (-)NCBI
RefSeq Acc Id: XM_039108050   ⟹   XP_038963978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,345 (-)NCBI
mRatBN7.24172,873,110 - 172,929,164 (-)NCBI
RefSeq Acc Id: XM_039108051   ⟹   XP_038963979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,658,695 (-)NCBI
mRatBN7.24172,873,110 - 172,927,524 (-)NCBI
RefSeq Acc Id: XM_039108052   ⟹   XP_038963980
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,631,850 (-)NCBI
mRatBN7.24172,873,110 - 172,900,685 (-)NCBI
RefSeq Acc Id: XM_063286453   ⟹   XP_063142523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,367 (-)NCBI
RefSeq Acc Id: XM_063286454   ⟹   XP_063142524
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,353 (-)NCBI
RefSeq Acc Id: XM_063286455   ⟹   XP_063142525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,306 (-)NCBI
RefSeq Acc Id: XM_063286456   ⟹   XP_063142526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,604,281 - 174,660,351 (-)NCBI
RefSeq Acc Id: XR_010065686
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84174,607,533 - 174,660,368 (-)NCBI
RefSeq Acc Id: NP_001012234   ⟸   NM_001012234
- UniProtKB: Q5FX52 (UniProtKB/Swiss-Prot),   A6IMM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237662   ⟸   XM_006237600
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_017448260   ⟸   XM_017592771
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000011376   ⟸   ENSRNOT00000011376
RefSeq Acc Id: XP_038963978   ⟸   XM_039108050
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963976   ⟸   XM_039108048
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963975   ⟸   XM_039108047
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963979   ⟸   XM_039108051
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038963974   ⟸   XM_039108046
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963980   ⟸   XM_039108052
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063142523   ⟸   XM_063286453
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063142524   ⟸   XM_063286454
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063142526   ⟸   XM_063286456
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063142525   ⟸   XM_063286455
- Peptide Label: isoform X3
Protein Domains
C2   EF-hand   PI-PLC X-box   PI-PLC Y-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5FX52-F1-model_v2 AlphaFold Q5FX52 1-645 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359567 AgrOrtholog
BioCyc Gene G2FUF-42543 BioCyc
BioCyc Pathway PWY-6351 [D-myo-inositol (1,4,5)-trisphosphate biosynthesis] BioCyc
  PWY-6367 [D-myo-inositol-5-phosphate metabolism] BioCyc
  PWY-8052 [2-arachidonoylglycerol biosynthesis] BioCyc
BioCyc Pathway Image PWY-6351 BioCyc
  PWY-6367 BioCyc
  PWY-8052 BioCyc
Ensembl Genes ENSRNOG00000008514 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055009010 UniProtKB/Swiss-Prot
  ENSRNOG00060008098 UniProtKB/Swiss-Prot
  ENSRNOG00065012010 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011376 ENTREZGENE
  ENSRNOT00000011376.5 UniProtKB/Swiss-Prot
  ENSRNOT00055015234 UniProtKB/Swiss-Prot
  ENSRNOT00060013405 UniProtKB/Swiss-Prot
  ENSRNOT00065019531 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.150 UniProtKB/Swiss-Prot
  3.20.20.190 UniProtKB/Swiss-Prot
  C2 domain UniProtKB/TrEMBL
  EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Phosphatidylinositol (PI) phosphodiesterase UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI-PLC_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC_EF-hand-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_C_Pinositol-sp_Y UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:497197 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 497197 ENTREZGENE
PANTHER 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE ZETA-1 UniProtKB/TrEMBL
  PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
  PTHR10336:SF29 UniProtKB/Swiss-Prot
Pfam EF-hand_like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF00168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Plcz1 PhenoGen
PRINTS PHPHLIPASEC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PIPLC_X_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PIPLC_Y_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008514 RatGTEx
  ENSRNOG00055009010 RatGTEx
  ENSRNOG00060008098 RatGTEx
  ENSRNOG00065012010 RatGTEx
SMART PLCXc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLCYc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP C2 domain (Calcium/lipid-binding domain, CaLB) UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
  PLC-like phosphodiesterases UniProtKB/TrEMBL
  SSF47473 UniProtKB/Swiss-Prot
  SSF49562 UniProtKB/Swiss-Prot
  SSF51695 UniProtKB/Swiss-Prot
UniProt A6IMM6 ENTREZGENE, UniProtKB/TrEMBL
  PLCZ1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-07-29 Plcz1  phospholipase C, zeta 1      Symbol and Name status set to provisional 70820 PROVISIONAL