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ONTOLOGY REPORT - ANNOTATIONS

Term:prevention of polyspermy
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Accession:GO:0060468 term browser browse the term
Definition:The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.
Synonyms:exact_synonym: negative regulation of fertilization involved in egg activation;   polyspermy block


show annotations for term's descendants           Sort by:
prevention of polyspermy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam24 ADAM metallopeptidase domain 24 acts_upstream_of_or_within ISO MGI:4437125 (PMID:19670298) RGD PMID:19670298 NCBI chr16:51,578,278...51,584,265
Ensembl chr16:51,578,277...51,584,312 		JBrowse link
G Astl astacin like metalloendopeptidase involved_in ISO
IEA 		(PMID:22472438)
GO_REF:0000107 		RGD
Ensembl		 PMID:22472438 GO_REF:0000107 NCBI chr 3:114,563,135...114,580,295
Ensembl chr 3:114,563,135...114,578,868 		JBrowse link
G Plat plasminogen activator, tissue type involved_in IDA PMID:1515147 UniProt PMID:1515147 RGD:42721992 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Tpst2 tyrosylprotein sulfotransferase 2 acts_upstream_of_or_within ISO MGI:3512111 (PMID:21339297) RGD PMID:21339297 NCBI chr12:44,321,875...44,363,892
Ensembl chr12:44,321,875...44,362,329 		JBrowse link
G Zp1 zona pellucida glycoprotein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:207,560,881...207,567,261
Ensembl chr 1:207,560,881...207,567,261 		JBrowse link
G Zp2 zona pellucida glycoprotein 2 involved_in ISS
ISO
IBA 		PMID:22472438
(PMID:22472438)
GO_REF:0000033 		RGD
GO_Central		 PMID:22472438 PMID:22472438 GO_REF:0000033, RGD:8554097 NCBI chr 1:174,513,507...174,525,288
Ensembl chr 1:174,513,511...174,525,288 		JBrowse link
G Zp4 zona pellucida glycoprotein 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr17:59,005,649...59,012,202
Ensembl chr17:59,005,649...59,012,202 		JBrowse link
cortical granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myh9 myosin, heavy chain 9 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:31118423) 		UniProt
Ensembl
RGD		 PMID:31118423 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Nlrp5 NLR family, pyrin domain containing 5 involved_in ISO (PMID:31118423) RGD PMID:31118423 NCBI chr 1:67,778,037...67,810,941
Ensembl chr 1:67,777,948...68,023,736 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    negative regulation of biological process 5844
      negative regulation of reproductive process 98
        negative regulation of fertilization 9
          prevention of polyspermy 9
            cortical granule exocytosis + 2
Path 2
Term Annotations click to browse term
  biological_process 20543
    reproductive process 1978
      sexual reproduction 1256
        fertilization 249
          single fertilization 199
            egg activation 14
              prevention of polyspermy 9
                cortical granule exocytosis + 2
paths to the root