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ONTOLOGY REPORT - ANNOTATIONS

Term:cortical granule exocytosis
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Accession:GO:0060471 term browser browse the term
Definition:The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.
Synonyms:related_synonym: cortical granule release;   cortical reaction


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cortical granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYH9 myosin heavy chain 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618 		JBrowse link
G NLRP5 NLR family pyrin domain containing 5 involved_in ISO (PMID:31118423) UniProt PMID:31118423 NCBI chr19:53,021,034...53,083,590
Ensembl chr19:61,818,345...61,879,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16644
    negative regulation of biological process 5571
      negative regulation of reproductive process 90
        negative regulation of fertilization 8
          prevention of polyspermy 8
            cortical granule exocytosis 2
              positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration 0
Path 2
Term Annotations click to browse term
  biological_process 16644
    localization 5259
      establishment of localization 4572
        transport 4273
          export from cell 1029
            secretion by cell 960
              exocytosis 367
                regulated exocytosis 258
                  calcium-ion regulated exocytosis 73
                    cortical granule exocytosis 2
                      positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration 0
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