ZP2 (zona pellucida glycoprotein 2) - Rat Genome Database

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Gene: ZP2 (zona pellucida glycoprotein 2) Pan paniscus
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Symbol: ZP2
Name: zona pellucida glycoprotein 2
RGD ID: 11809452
Description: ENCODES a protein that exhibits acrosin binding (inferred); identical protein binding (inferred); structural constituent of egg coat (inferred); INVOLVED IN binding of sperm to zona pellucida (ortholog); humoral immune response mediated by circulating immunoglobulin (ortholog); regulation of acrosome reaction (ortholog); ASSOCIATED WITH genetic disease (ortholog); Oocyte/Zygote/Embryo Maturation Arrest 6 (ortholog); FOUND IN inclusion body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zona pellucida sperm-binding protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21822,365,697 - 22,380,566 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11626,886,199 - 26,901,082 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01617,193,632 - 17,210,667 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11621,227,285 - 21,244,316 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1621,227,285 - 21,244,316 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ZP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21822,365,697 - 22,380,566 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11626,886,199 - 26,901,082 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01617,193,632 - 17,210,667 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11621,227,285 - 21,244,316 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1621,227,285 - 21,244,316 (-)Ensemblpanpan1.1panPan2
ZP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381621,197,450 - 21,214,510 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1621,197,450 - 21,214,510 (-)EnsemblGRCh38hg38GRCh38
GRCh371621,208,771 - 21,225,831 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361621,116,274 - 21,130,369 (-)NCBINCBI36Build 36hg18NCBI36
Build 341621,116,273 - 21,130,369NCBI
Celera1620,518,619 - 20,532,706 (-)NCBICelera
Cytogenetic Map16p12.3-p12.2NCBI
HuRef1619,743,981 - 19,758,073 (-)NCBIHuRef
CHM1_11621,296,024 - 21,310,120 (-)NCBICHM1_1
T2T-CHM13v2.01621,128,399 - 21,145,450 (-)NCBIT2T-CHM13v2.0
Zp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397119,725,985 - 119,744,514 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7119,725,995 - 119,744,514 (-)EnsemblGRCm39 Ensembl
GRCm387120,126,762 - 120,145,291 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7120,126,772 - 120,145,291 (-)EnsemblGRCm38mm10GRCm38
MGSCv377127,275,875 - 127,288,804 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367119,923,510 - 119,936,439 (-)NCBIMGSCv36mm8
Celera7120,041,987 - 120,054,607 (-)NCBICelera
Cytogenetic Map7F2NCBI
cM Map764.38NCBI
Zp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81183,944,840 - 183,956,619 (-)NCBIGRCr8
mRatBN7.21174,513,507 - 174,525,288 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1174,513,511 - 174,525,288 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1182,831,061 - 182,842,857 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01190,017,103 - 190,028,901 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,751,032 - 182,762,847 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01189,899,906 - 189,911,650 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1189,899,892 - 189,911,650 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01196,829,189 - 196,840,820 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1172,263,179 - 172,274,910 (-)NCBICelera
Cytogenetic Map1q36NCBI
Zp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955493400,868 - 412,596 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955493400,868 - 412,660 (-)NCBIChiLan1.0ChiLan1.0
ZP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1624,230,202 - 24,242,441 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl624,230,201 - 24,242,451 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha625,667,939 - 25,680,181 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0624,381,539 - 24,393,787 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl624,381,539 - 24,393,797 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1624,184,937 - 24,197,176 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0624,078,588 - 24,090,826 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0624,463,951 - 24,476,253 (+)NCBIUU_Cfam_GSD_1.0
Zp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344118,296,926 - 118,311,637 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365016,394,838 - 6,407,442 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365016,394,838 - 6,407,512 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl324,863,730 - 24,877,522 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1324,863,730 - 24,877,522 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2325,665,412 - 25,679,349 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1519,318,026 - 19,338,966 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl519,319,034 - 19,338,495 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606810,543,555 - 10,560,816 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247827,275,207 - 7,287,114 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247827,275,156 - 7,287,480 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000051632   ⟹   ENSPPAP00000028784
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1621,227,285 - 21,244,316 (-)Ensembl
RefSeq Acc Id: XM_034939551   ⟹   XP_034795442
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21822,365,697 - 22,380,566 (-)NCBI
NHGRI_mPanPan11626,886,199 - 26,901,082 (-)NCBI
Mhudiblu_PPA_v01617,196,122 - 17,210,667 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034795442 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028784.1
RefSeq Acc Id: XP_034795442   ⟸   XM_034939551
- UniProtKB: A0A2R9BGN4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000028784   ⟸   ENSPPAT00000051632
Protein Domains
ZP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037420 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000051632.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.4100 UniProtKB/TrEMBL
  Zona pellucida, ZP-N domain UniProtKB/TrEMBL
InterPro ZP-C UniProtKB/TrEMBL
  ZP_chr UniProtKB/TrEMBL
  ZP_dom UniProtKB/TrEMBL
  ZP_dom_CS UniProtKB/TrEMBL
NCBI Gene ZP2 ENTREZGENE
PANTHER ZONA PELLUCIDA SPERM-BINDING PROTEIN UniProtKB/TrEMBL
  ZONA PELLUCIDA SPERM-BINDING PROTEIN 2 UniProtKB/TrEMBL
Pfam Zona_pellucida UniProtKB/TrEMBL
PRINTS ZPELLUCIDA UniProtKB/TrEMBL
PROSITE ZP_1 UniProtKB/TrEMBL
  ZP_2 UniProtKB/TrEMBL
SMART SM00241 UniProtKB/TrEMBL
UniProt A0A2R9BGN4 ENTREZGENE, UniProtKB/TrEMBL