TPST2 (tyrosylprotein sulfotransferase 2) - Rat Genome Database

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Gene: TPST2 (tyrosylprotein sulfotransferase 2) Pan paniscus
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Symbol: TPST2
Name: tyrosylprotein sulfotransferase 2
RGD ID: 11697230
Description: ENCODES a protein that exhibits protein homodimerization activity (inferred); protein-tyrosine sulfotransferase activity (inferred); transferase activity (inferred); INVOLVED IN fusion of sperm to egg plasma membrane involved in single fertilization (ortholog); prevention of polyspermy (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); cataract 23 (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (inferred); Golgi apparatus (inferred); Golgi membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein-tyrosine sulfotransferase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22336,531,196 - 36,595,395 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12239,229,633 - 39,293,863 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0227,587,446 - 7,651,645 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12225,309,254 - 25,334,638 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2225,309,254 - 25,334,638 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TPST2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22336,531,196 - 36,595,395 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12239,229,633 - 39,293,863 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0227,587,446 - 7,651,645 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12225,309,254 - 25,334,638 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2225,309,254 - 25,334,638 (-)Ensemblpanpan1.1panPan2
TPST2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382226,521,996 - 26,590,132 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2226,521,996 - 26,596,717 (-)EnsemblGRCh38hg38GRCh38
GRCh372226,917,962 - 26,986,096 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362225,251,714 - 25,316,089 (-)NCBINCBI36Build 36hg18NCBI36
Build 342225,246,269 - 25,310,643NCBI
Celera2210,725,568 - 10,789,890 (-)NCBICelera
Cytogenetic Map22q12.1NCBI
HuRef229,869,106 - 9,933,721 (-)NCBIHuRef
CHM1_12226,880,965 - 26,945,609 (-)NCBICHM1_1
T2T-CHM13v2.02226,984,404 - 27,052,464 (-)NCBIT2T-CHM13v2.0
Tpst2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395112,424,548 - 112,463,222 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5112,424,557 - 112,463,227 (+)EnsemblGRCm39 Ensembl
GRCm385112,276,682 - 112,315,356 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5112,276,691 - 112,315,361 (+)EnsemblGRCm38mm10GRCm38
MGSCv375112,705,727 - 112,744,376 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365112,517,029 - 112,555,659 (+)NCBIMGSCv36mm8
Celera5109,396,281 - 109,435,190 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map554.65NCBI
Tpst2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81249,982,281 - 50,024,489 (-)NCBIGRCr8
mRatBN7.21244,321,875 - 44,363,892 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1244,321,875 - 44,362,329 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1245,490,785 - 45,531,171 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01246,101,129 - 46,141,600 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01245,161,667 - 45,202,131 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01250,343,076 - 50,383,534 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1250,343,086 - 50,383,496 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01252,099,677 - 52,141,423 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41914,283,684 - 14,297,517 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11914,290,594 - 14,302,342 (+)NCBI
Celera1245,904,930 - 45,945,380 (-)NCBICelera
Cytogenetic Map12q16NCBI
Tpst2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554551,106,294 - 1,129,196 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554551,106,403 - 1,128,455 (-)NCBIChiLan1.0ChiLan1.0
TPST2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12620,199,731 - 20,240,084 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2620,199,754 - 20,212,869 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2620,063,735 - 20,115,947 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02620,563,110 - 20,615,356 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2620,563,112 - 20,615,982 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12620,296,215 - 20,336,928 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02620,535,592 - 20,587,560 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02620,605,612 - 20,657,891 (-)NCBIUU_Cfam_GSD_1.0
Tpst2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118114,713,206 - 114,726,168 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366571,144,292 - 1,157,507 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366571,144,526 - 1,157,501 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TPST2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1444,122,159 - 44,145,822 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11444,122,156 - 44,140,654 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21447,001,956 - 47,066,378 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TPST2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1199,427,529 - 9,490,992 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl199,426,162 - 9,446,863 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045116,611,623 - 116,675,737 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tpst2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247473,065,098 - 3,083,279 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247473,065,217 - 3,118,526 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000060450   ⟹   ENSPPAP00000037550
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2225,309,254 - 25,334,638 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000060453   ⟹   ENSPPAP00000037553
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2225,315,689 - 25,325,157 (-)Ensembl
RefSeq Acc Id: XM_034949272   ⟹   XP_034805163
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22336,531,196 - 36,595,395 (-)NCBI
NHGRI_mPanPan12239,229,633 - 39,293,863 (-)NCBI
Mhudiblu_PPA_v0227,587,446 - 7,651,645 (-)NCBI
RefSeq Acc Id: XM_034949273   ⟹   XP_034805164
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22336,531,196 - 36,570,719 (-)NCBI
NHGRI_mPanPan12239,229,633 - 39,269,156 (-)NCBI
Mhudiblu_PPA_v0227,587,446 - 7,626,995 (-)NCBI
RefSeq Acc Id: XM_034949274   ⟹   XP_034805165
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22336,531,196 - 36,580,836 (-)NCBI
NHGRI_mPanPan12239,229,633 - 39,279,287 (-)NCBI
Mhudiblu_PPA_v0227,587,446 - 7,637,067 (-)NCBI
RefSeq Acc Id: XR_010111743
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22336,531,196 - 36,595,395 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034805163 (Get FASTA)   NCBI Sequence Viewer  
  XP_034805164 (Get FASTA)   NCBI Sequence Viewer  
  XP_034805165 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000037550.1
  ENSPPAP00000037553.1
RefSeq Acc Id: XP_034805163   ⟸   XM_034949272
- UniProtKB: A0A2R9C6J6 (UniProtKB/TrEMBL),   A0A2R9C9D4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034805165   ⟸   XM_034949274
- UniProtKB: A0A2R9C6J6 (UniProtKB/TrEMBL),   A0A2R9C9D4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034805164   ⟸   XM_034949273
- UniProtKB: A0A2R9C6J6 (UniProtKB/TrEMBL),   A0A2R9C9D4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000037550   ⟸   ENSPPAT00000060450
RefSeq Acc Id: ENSPPAP00000037553   ⟸   ENSPPAT00000060453


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041524 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060450.1 UniProtKB/TrEMBL
  ENSPPAT00000060453.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  TPST UniProtKB/TrEMBL
NCBI Gene TPST2 ENTREZGENE
PANTHER PROTEIN-TYROSINE SULFOTRANSFERASE 2 UniProtKB/TrEMBL
  PTHR12788 UniProtKB/TrEMBL
Pfam Sulfotransfer_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9C6J6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C9D4 ENTREZGENE, UniProtKB/TrEMBL