CACNA1H (calcium voltage-gated channel subunit alpha1 H) - Rat Genome Database

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Gene: CACNA1H (calcium voltage-gated channel subunit alpha1 H) Pan paniscus
Analyze
Symbol: CACNA1H
Name: calcium voltage-gated channel subunit alpha1 H
RGD ID: 12034848
Description: ENCODES a protein that exhibits low voltage-gated calcium channel activity (ortholog); scaffold protein binding (ortholog); voltage-gated ion channel activity (ortholog); INVOLVED IN aldosterone biosynthetic process (ortholog); calcium ion import (ortholog); calcium ion transport (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH arteriovenous malformations of the brain (ortholog); autistic disorder (ortholog); beta thalassemia (ortholog); FOUND IN caveola (ortholog); cytoplasm (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: voltage-dependent T-type calcium channel subunit alpha-1H
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1161,195,991 - 1,222,917 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl161,195,364 - 1,222,917 (+)Ensemblpanpan1.1panPan2


Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway  (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
calcium transport pathway  (ISO)
calcium/calcium-mediated signaling pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

Genomics

Comparative Map Data
CACNA1H
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1161,195,991 - 1,222,917 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl161,195,364 - 1,222,917 (+)Ensemblpanpan1.1panPan2
CACNA1H
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl161,153,106 - 1,221,771 (+)EnsemblGRCh38hg38GRCh38
GRCh38161,153,106 - 1,221,769 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37161,203,106 - 1,271,768 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,143,242 - 1,211,773 (+)NCBINCBI36hg18NCBI36
Build 34161,143,241 - 1,211,772NCBI
Celera161,418,957 - 1,487,666 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef161,111,743 - 1,204,831 (+)NCBIHuRef
CHM1_1161,179,129 - 1,271,446 (+)NCBICHM1_1
Cacna1h
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391725,593,259 - 25,655,308 (-)NCBIGRCm39mm39
GRCm39 Ensembl1725,593,259 - 25,652,757 (-)Ensembl
GRCm381725,374,285 - 25,436,334 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1725,374,285 - 25,433,783 (-)EnsemblGRCm38mm10GRCm38
MGSCv371725,511,232 - 25,570,728 (-)NCBIGRCm37mm9NCBIm37
MGSCv361725,101,887 - 25,161,368 (-)NCBImm8
Celera1725,902,087 - 25,961,468 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.53NCBI
Cacna1h
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21014,390,104 - 14,448,204 (-)NCBI
Rnor_6.0 Ensembl1014,730,941 - 14,788,617 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01014,730,932 - 14,789,201 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01014,547,456 - 14,605,627 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41014,621,372 - 14,679,051 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11014,621,371 - 14,679,051 (-)NCBI
Celera1014,061,778 - 14,119,454 (-)NCBICelera
Cytogenetic Map10q12NCBI
Cacna1h
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,045,895 - 16,108,862 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,047,965 - 16,108,862 (-)NCBIChiLan1.0ChiLan1.0
CACNA1H
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1639,510,129 - 39,533,129 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl639,510,121 - 39,533,753 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,776,915 - 40,826,321 (-)NCBI
ROS_Cfam_1.0639,855,337 - 39,904,743 (-)NCBI
UMICH_Zoey_3.1639,531,855 - 39,581,243 (-)NCBI
UNSW_CanFamBas_1.0639,504,487 - 39,553,874 (-)NCBI
UU_Cfam_GSD_1.0639,983,132 - 40,032,548 (-)NCBI
Cacna1h
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344103,984,951 - 104,007,239 (+)NCBI
SpeTri2.0NW_0049366942,702,224 - 2,724,574 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CACNA1H
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl340,637,436 - 40,694,818 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1340,637,420 - 40,694,616 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CACNA1H
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,039,709 - 1,106,212 (+)NCBI
ChlSab1.1 Ensembl51,078,973 - 1,106,507 (+)Ensembl
Cacna1h
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249131,926,405 - 1,952,426 (+)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003808844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008960944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008960945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008960947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008960948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008960949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008960950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008960951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014341618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034951641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034951642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034951643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034951644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034951645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034951646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034951647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034951648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000045233   ⟹   ENSPPAP00000022423
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl161,195,364 - 1,222,139 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045243   ⟹   ENSPPAP00000022433
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl161,195,991 - 1,222,917 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045248   ⟹   ENSPPAP00000022438
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl161,195,995 - 1,222,139 (+)Ensembl
RefSeq Acc Id: XM_003808844   ⟹   XP_003808892
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1161,195,991 - 1,222,917 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960944   ⟹   XP_008959192
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1161,195,991 - 1,222,917 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960945   ⟹   XP_008959193
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1161,195,991 - 1,222,917 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960947   ⟹   XP_008959195
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1161,195,991 - 1,222,917 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960948   ⟹   XP_008959196
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1161,197,144 - 1,222,917 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960949   ⟹   XP_008959197
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1161,200,347 - 1,222,917 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960950   ⟹   XP_008959198
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1161,197,514 - 1,222,917 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960951   ⟹   XP_008959199
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1161,197,514 - 1,222,917 (+)NCBI
Sequence:
RefSeq Acc Id: XM_014341618   ⟹   XP_014197104
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1161,195,991 - 1,222,917 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_008959192   ⟸   XM_008960944
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008959193   ⟸   XM_008960945
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_014197104   ⟸   XM_014341618
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003808892   ⟸   XM_003808844
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008959195   ⟸   XM_008960947
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008959196   ⟸   XM_008960948
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008959198   ⟸   XM_008960950
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_008959199   ⟸   XM_008960951
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_008959197   ⟸   XM_008960949
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: ENSPPAP00000022423   ⟸   ENSPPAT00000045233
RefSeq Acc Id: ENSPPAP00000022438   ⟸   ENSPPAT00000045248
RefSeq Acc Id: ENSPPAP00000022433   ⟸   ENSPPAT00000045243
Protein Domains
Ion_trans


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034389 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000022423 UniProtKB/TrEMBL
  ENSPPAP00000022433 UniProtKB/TrEMBL
  ENSPPAP00000022438 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045233 UniProtKB/TrEMBL
  ENSPPAT00000045243 UniProtKB/TrEMBL
  ENSPPAT00000045248 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.350 UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  VDCC_T_a1 UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
NCBI Gene CACNA1H ENTREZGENE
Pfam Ion_trans UniProtKB/TrEMBL
PRINTS TVDCCALPHA1 UniProtKB/TrEMBL
UniProt A0A2R9AZF6_PANPA UniProtKB/TrEMBL
  A0A2R9AZG8_PANPA UniProtKB/TrEMBL
  A0A2R9AZH3_PANPA UniProtKB/TrEMBL