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ONTOLOGY REPORT - ANNOTATIONS

Term:penetration of zona pellucida
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Accession:GO:0007341 term browser browse the term
Definition:The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.


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penetration of zona pellucida term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acr acrosin acts_upstream_of_or_within TAS
ISO
IMP		 MGI:2180087|MGI:2429958|MGI:96945 (MGI:3042304|PMID:15051954), (MGI:69844|PMID:7989357), (MGI:86042|PMID:9041140) RGD PMID:7989357 PMID:9041140 PMID:15051954 PMID:8037773 PMID:28859281 MGI:3042304 MGI:69844 MGI:86042, RGD:1299864, RGD:13464336 NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474 		JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2178779 (MGI:1098917|PMID:9374408)		 Ensembl
RGD		 PMID:9374408 GO_REF:0000107 MGI:1098917 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461 		JBrowse link
G Dkkl1 dickkopf like acrosomal protein 1 involved_in ISO (MGI:4438468|PMID:19596312) RGD PMID:19596312 MGI:4438468 NCBI chr 1:95,694,010...95,699,259
Ensembl chr 1:95,694,010...95,699,259 		JBrowse link
G Hexb hexosaminidase subunit beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3582046|PMID:8269854)		 Ensembl
RGD		 PMID:8269854 GO_REF:0000107 MGI:3582046 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223 		JBrowse link
G Hyal3 hyaluronidase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4834982|PMID:20586096)		 UniProt
RGD		 PMID:20586096 GO_REF:0000024 MGI:4834982 NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647 		JBrowse link
G Hyal5 hyaluronoglucosaminidase 5 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 4:53,341,105...53,412,280
Ensembl chr 4:53,343,475...53,370,785 		JBrowse link
G Pithd1 PITH domain containing 1 acts_upstream_of_or_within ISO MGI:6416147 (MGI:6392185|PMID:31915251) RGD PMID:31915251 MGI:6392185 NCBI chr 5:148,205,995...148,216,490
Ensembl chr 5:148,205,998...148,217,080 		JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma acts_upstream_of_or_within ISO MGI:5788175 (MGI:5697739|PMID:26429887) RGD PMID:26429887 MGI:5697739 NCBI chr15:45,289,917...45,362,012
Ensembl chr15:45,290,373...45,361,832 		JBrowse link
G Ppp3r2 protein phosphatase 3, regulatory subunit B, beta acts_upstream_of_or_within ISO MGI:5788176 (MGI:5697739|PMID:26429887) RGD PMID:26429887 MGI:5697739 NCBI chr 5:64,026,903...64,027,898
Ensembl chr 5:64,026,903...64,032,548 		JBrowse link
G Smcp sperm mitochondria-associated cysteine-rich protein acts_upstream_of_or_within ISO MGI:2387973|MGI:87884 (MGI:2386493|PMID:11940662), (MGI:3042304|PMID:15051954) RGD PMID:11940662 PMID:15051954 MGI:2386493 MGI:3042304 NCBI chr 2:178,160,948...178,165,951
Ensembl chr 2:178,160,127...178,166,001 		JBrowse link
G Tbxt T-box transcription factor T acts_upstream_of_or_within ISO MGI:1856570|MGI:1856722 (MGI:71219|PMID:7883069) RGD PMID:7883069 MGI:71219 NCBI chr 1:52,298,104...52,309,813
Ensembl chr 1:52,298,099...52,305,864 		JBrowse link
G Tnp2 transition protein 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2180779 (MGI:2180725|PMID:11385107)		 RGD PMID:11385107 PMID:21873635 MGI:2180725, RGD:13792537 NCBI chr10:4,879,812...4,880,540
Ensembl chr10:4,879,812...4,880,538 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    multicellular organismal process 9171
      multi-multicellular organism process 344
        penetration of zona pellucida 12
Path 2
Term Annotations click to browse term
  biological_process 19574
    reproduction 1826
      reproductive process 1816
        fertilization 210
          single fertilization 161
            penetration of zona pellucida 12
paths to the root