LYZL4 (lysozyme like 4) - Rat Genome Database

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Gene: LYZL4 (lysozyme like 4) Pan paniscus
Analyze
Symbol: LYZL4
Name: lysozyme like 4
RGD ID: 11806210
Description: ENCODES a protein that exhibits lysozyme activity (ortholog); INVOLVED IN defense response to bacterium (ortholog); defense response to Gram-negative bacterium (ortholog); ASSOCIATED WITH congenital muscular dystrophy-dystroglycanopathy type A8 (ortholog); genetic disease (ortholog); FOUND IN acrosomal vesicle (inferred); extracellular space (inferred); sperm flagellum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lysozyme-like protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2242,321,193 - 42,435,726 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1342,325,955 - 42,440,488 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0342,302,237 - 42,378,700 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1342,565,535 - 42,579,033 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl342,565,535 - 42,579,033 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
lysozyme activity  (IEA,ISO)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LYZL4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2242,321,193 - 42,435,726 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1342,325,955 - 42,440,488 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0342,302,237 - 42,378,700 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1342,565,535 - 42,579,033 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl342,565,535 - 42,579,033 (-)Ensemblpanpan1.1panPan2
LYZL4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38342,360,764 - 42,410,610 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl342,397,083 - 42,410,610 (-)EnsemblGRCh38hg38GRCh38
GRCh37342,438,575 - 42,452,102 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36342,413,579 - 42,427,069 (-)NCBINCBI36Build 36hg18NCBI36
Build 34342,413,578 - 42,427,069NCBI
Celera342,378,992 - 42,392,482 (-)NCBICelera
Cytogenetic Map3p22.1NCBI
HuRef342,482,777 - 42,496,267 (-)NCBIHuRef
CHM1_1342,389,883 - 42,403,363 (-)NCBICHM1_1
T2T-CHM13v2.0342,378,784 - 42,445,904 (-)NCBIT2T-CHM13v2.0
Lyzl4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399121,406,907 - 121,471,187 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9121,406,909 - 121,471,162 (-)EnsemblGRCm39 Ensembl
GRCm389121,577,841 - 121,642,121 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9121,577,843 - 121,642,096 (-)EnsemblGRCm38mm10GRCm38
MGSCv379121,486,961 - 121,550,684 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369121,426,541 - 121,490,264 (-)NCBIMGSCv36mm8
Celera9122,047,977 - 122,114,890 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map972.45NCBI
Lyzl4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88130,125,641 - 130,132,872 (-)NCBIGRCr8
mRatBN7.28121,248,129 - 121,255,366 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8121,248,168 - 121,255,353 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8126,846,758 - 126,854,016 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08125,045,821 - 125,053,079 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08122,875,529 - 122,882,782 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08130,219,984 - 130,228,066 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8130,220,018 - 130,224,444 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08129,406,646 - 129,414,058 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48126,588,240 - 126,592,666 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18126,607,941 - 126,621,696 (-)NCBI
Celera8120,383,010 - 120,387,460 (-)NCBICelera
Cytogenetic Map8q32NCBI
Lyzl4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542028,336,162 - 28,344,635 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542028,333,984 - 28,344,180 (+)NCBIChiLan1.0ChiLan1.0
LYZL4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12311,526,560 - 11,540,724 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2311,526,697 - 11,540,554 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2311,564,493 - 11,582,132 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02311,814,715 - 11,832,371 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2311,814,840 - 11,832,366 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12311,616,455 - 11,634,094 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02311,758,878 - 11,776,523 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02311,763,105 - 11,780,752 (-)NCBIUU_Cfam_GSD_1.0
Lyzl4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118200,312,428 - 200,322,446 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366952,668,444 - 2,674,605 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366952,668,444 - 2,674,605 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LYZL4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1325,987,314 - 25,995,089 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11325,987,662 - 25,992,607 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21328,656,765 - 28,664,020 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LYZL4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1223,803,258 - 3,855,368 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041163,347,442 - 163,356,876 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lyzl4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473077,220,928 - 77,224,946 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000059938   ⟹   ENSPPAP00000037042
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl342,565,535 - 42,579,033 (-)Ensembl
RefSeq Acc Id: XM_055109734   ⟹   XP_054965709
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2242,359,289 - 42,373,166 (-)NCBI
NHGRI_mPanPan1342,364,051 - 42,377,928 (-)NCBI
RefSeq Acc Id: XM_055109735   ⟹   XP_054965710
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2242,359,289 - 42,373,184 (-)NCBI
NHGRI_mPanPan1342,364,051 - 42,377,946 (-)NCBI
RefSeq Acc Id: XM_055109736   ⟹   XP_054965711
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2242,359,289 - 42,373,182 (-)NCBI
NHGRI_mPanPan1342,364,051 - 42,377,944 (-)NCBI
RefSeq Acc Id: XM_055109737   ⟹   XP_054965712
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2242,321,193 - 42,373,144 (-)NCBI
NHGRI_mPanPan1342,325,955 - 42,377,906 (-)NCBI
RefSeq Acc Id: XM_063602280   ⟹   XP_063458350
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2242,359,283 - 42,435,726 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054965709 (Get FASTA)   NCBI Sequence Viewer  
  XP_054965710 (Get FASTA)   NCBI Sequence Viewer  
  XP_054965711 (Get FASTA)   NCBI Sequence Viewer  
  XP_054965712 (Get FASTA)   NCBI Sequence Viewer  
  XP_063458350 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000037042.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000037042   ⟸   ENSPPAT00000059938
RefSeq Acc Id: XP_054965712   ⟸   XM_055109737
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054965710   ⟸   XM_055109735
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CFM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054965711   ⟸   XM_055109736
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CFM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054965709   ⟸   XM_055109734
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CFM4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063458350   ⟸   XM_063602280
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CFM4 (UniProtKB/TrEMBL)
Protein Domains
Glycosyl hydrolases family 22 (GH22)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041271 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000059938.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.530.10 UniProtKB/TrEMBL
InterPro Glyco_hydro_22 UniProtKB/TrEMBL
  Glyco_hydro_22_CS UniProtKB/TrEMBL
  Glyco_hydro_22_lys UniProtKB/TrEMBL
  Lysozyme-like_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100979654 UniProtKB/TrEMBL
NCBI Gene LYZL4 ENTREZGENE
PANTHER PTHR11407 UniProtKB/TrEMBL
  PTHR11407:SF21 UniProtKB/TrEMBL
Pfam Lys UniProtKB/TrEMBL
PRINTS LYSOZYME UniProtKB/TrEMBL
  LYZLACT UniProtKB/TrEMBL
PROSITE GLYCOSYL_HYDROL_F22_1 UniProtKB/TrEMBL
  GLYCOSYL_HYDROL_F22_2 UniProtKB/TrEMBL
SMART LYZ1 UniProtKB/TrEMBL
Superfamily-SCOP SSF53955 UniProtKB/TrEMBL
UniProt A0A2R9CFM4 ENTREZGENE, UniProtKB/TrEMBL