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ONTOLOGY REPORT - ANNOTATIONS

Term:fusion of sperm to egg plasma membrane involved in single fertilization
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Accession:GO:0007342 term browser browse the term
Definition:The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.
Synonyms:narrow_synonym: sperm-oocyte fusion


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fusion of sperm to egg plasma membrane involved in single fertilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1h16orf92 similar to human chromosome 16 open reading frame 92 involved_in ISO (PMID:32295885) RGD PMID:32295885 NCBI chr 1:181,434,524...181,441,000 JBrowse link
G Catsper1 cation channel, sperm associated 1 acts_upstream_of_or_within ISO MGI:2387461 (PMID:11595941) RGD PMID:11595941 NCBI chr 1:202,643,009...202,652,059
Ensembl chr 1:202,643,038...202,651,824 		JBrowse link
G Cd9 CD9 molecule involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:10634790), (PMID:10634791), (PMID:10700183), (PMID:21690351)
GO_REF:0000107
(PMID:14575715)		 UniProt
RGD
Ensembl		 PMID:10634790 PMID:10634791 PMID:10700183 PMID:14575715 PMID:21690351 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Dcst1 DC-STAMP domain containing 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:33871360)
(PMID:35393517)		 RGD PMID:33871360 PMID:35393517 NCBI chr 2:174,765,203...174,784,023
Ensembl chr 2:174,765,350...174,781,806 		JBrowse link
G Dcst2 DC-STAMP domain containing 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:35393517)
(PMID:33871360)		 RGD PMID:33871360 PMID:35393517 NCBI chr 2:174,781,806...174,795,834
Ensembl chr 2:174,781,902...174,795,832 		JBrowse link
G Eqtn equatorin involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000002
(PMID:9674989)
GO_REF:0000033		 InterPro
RGD
GO_Central		 PMID:9674989 GO_REF:0000002 GO_REF:0000033 NCBI chr 5:109,734,495...109,762,048
Ensembl chr 5:109,728,999...109,761,840 		JBrowse link
G Folr1 folate receptor alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Folr2 folate receptor beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724 		JBrowse link
G Frey1 Frey regulator of sperm-oocyte fusion 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:36787362)
(PMID:35960805), (PMID:36050562)		 GO_Central
RGD		 PMID:35960805 PMID:36050562 PMID:36787362 GO_REF:0000033 NCBI chr 3:78,354,303...78,355,055
Ensembl chr 3:78,354,303...78,355,055 		JBrowse link
G Glipr1l1 GLIPR1 like 1 involved_in ISO (PMID:31672133) RGD PMID:31672133 NCBI chr 7:47,550,637...47,577,611
Ensembl chr 7:47,550,631...47,577,617 		JBrowse link
G Hyal5 hyaluronoglucosaminidase 5 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:53,341,105...53,412,280
Ensembl chr 4:53,343,475...53,370,785 		JBrowse link
G Itga3 integrin subunit alpha 3 NOT|acts_upstream_of_or_within ISO MGI:1857792 (PMID:12591243) RGD PMID:12591243 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118 		JBrowse link
G Izumo1 izumo sperm-oocyte fusion 1 involved_in ISO
IBA
ISS		 (PMID:15759005)
(PMID:15759005), (PMID:24739963), (PMID:31672133), (PMID:35960805)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:15759005 PMID:24739963 PMID:31672133 PMID:35960805 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:96,090,817...96,096,893 JBrowse link
G Izumo1r IZUMO1 receptor, JUNO involved_in IBA
ISS
ISO		 GO_REF:0000033
GO_REF:0000024
(PMID:30517645)
(PMID:24739963), (PMID:27416963)		 GO_Central
UniProt
RGD		 PMID:24739963 PMID:27416963 PMID:30517645 GO_REF:0000024 GO_REF:0000033 NCBI chr 8:11,744,384...11,748,131
Ensembl chr 8:11,725,863...11,748,465 		JBrowse link
G Llcfc1 LLLL and CFNLAS motif containing 1 involved_in IBA
ISO		 GO_REF:0000033
(PMID:32393636)		 GO_Central
RGD		 PMID:32393636 GO_REF:0000033 NCBI chr 4:70,566,206...70,567,592
Ensembl chr 4:70,566,295...70,567,586 		JBrowse link
G Lyzl4 lysozyme-like 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:121,248,129...121,255,366
Ensembl chr 8:121,248,168...121,255,353 		JBrowse link
G Lyzl6 lysozyme-like 6 involved_in ISO
IBA		 (PMID:24013621)
GO_REF:0000033		 RGD
GO_Central		 PMID:24013621 GO_REF:0000033 NCBI chr10:88,544,342...88,549,177
Ensembl chr10:88,544,342...88,549,177 		JBrowse link
G Spaca3 sperm acrosome associated 3 involved_in ISO
IBA		 (PMID:15982649)
GO_REF:0000033		 RGD
GO_Central		 PMID:15982649 GO_REF:0000033 NCBI chr10:65,850,618...65,858,090
Ensembl chr10:65,854,893...65,858,094 		JBrowse link
G Spaca5 sperm acrosome associated 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:918,817...922,000
Ensembl chr  X:918,817...922,049 		JBrowse link
G Spaca6 sperm acrosome associated 6 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:32210282), (PMID:32393636)
MGI:5514186 (PMID:24275887)		 GO_Central
RGD		 PMID:24275887 PMID:32210282 PMID:32393636 GO_REF:0000033 NCBI chr 1:58,672,128...58,689,309
Ensembl chr 1:58,677,797...58,688,562 		JBrowse link
G Spam1 sperm adhesion molecule 1 TAS RGD PMID:8914077 RGD:634179 NCBI chr 4:53,302,745...53,312,913
Ensembl chr 4:53,302,745...53,312,908 		JBrowse link
G Spata46 spermatogenesis associated 46 involved_in ISO (PMID:27488028) RGD PMID:27488028 NCBI chr13:82,541,183...82,544,808
Ensembl chr13:82,541,183...82,544,808 		JBrowse link
G Spesp1 sperm equatorial segment protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000002
MGI:4838302 (PMID:20375058)
GO_REF:0000033		 InterPro
RGD
GO_Central		 PMID:20375058 GO_REF:0000002 GO_REF:0000033 NCBI chr 8:62,751,313...62,766,657
Ensembl chr 8:62,751,297...62,766,718 		JBrowse link
G Sppl2c signal peptide peptidase like 2C involved_in ISO (PMID:35960805) RGD PMID:35960805 NCBI chr10:89,095,279...89,097,487
Ensembl chr10:89,095,261...89,098,580 		JBrowse link
G Tmem95 transmembrane protein 95 involved_in IBA
ISO		 GO_REF:0000033
(PMID:32393636), (PMID:32484434), (PMID:34982145)
(PMID:36161911)		 GO_Central
RGD		 PMID:32393636 PMID:32484434 PMID:34982145 PMID:36161911 GO_REF:0000033 NCBI chr10:54,599,799...54,601,746
Ensembl chr10:54,599,800...54,601,790 		JBrowse link
G Tpst2 tyrosylprotein sulfotransferase 2 acts_upstream_of_or_within ISO MGI:3512111 (PMID:21339297) RGD PMID:21339297 NCBI chr12:44,321,875...44,363,892
Ensembl chr12:44,321,875...44,362,329 		JBrowse link
G Wdr54 WD repeat domain 54 involved_in IMP PMID:37951137 UniProt PMID:37951137 RGD:408345208 NCBI chr 4:115,654,968...115,677,979
Ensembl chr 4:115,654,968...115,661,562 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      cellular process involved in reproduction in multicellular organism 510
        fusion of sperm to egg plasma membrane involved in single fertilization 27
          negative regulation of fusion of sperm to egg plasma membrane 0
          regulation of fusion of sperm to egg plasma membrane + 0
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      cellular component organization or biogenesis 7178
        cellular component organization 6923
          endomembrane system organization 578
            plasma membrane organization 174
              plasma membrane fusion 30
                fusion of sperm to egg plasma membrane involved in single fertilization 27
                  negative regulation of fusion of sperm to egg plasma membrane 0
                  regulation of fusion of sperm to egg plasma membrane + 0
paths to the root