ONTOLOGY REPORT - ANNOTATIONS
Term: fusion of sperm to egg plasma membrane involved in single fertilization
Accession: GO:0007342
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Definition: The binding and fusion of a sperm, with the plasma membrane of the oocyte as part of the process of single fertilization. In sperm with flagella, binding occurs at the posterior (post-acrosomal) region of the sperm head.
Synonyms: narrow_synonym: sperm-oocyte fusion
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C1h16orf92
similar to human chromosome 16 open reading frame 92
involved_in
ISO
(PMID:32295885)
RGD
PMID:32295885
NCBI chr 1:181,434,524...181,441,000
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Catsper1
cation channel, sperm associated 1
acts_upstream_of_or_within
ISO
MGI:2387461 (PMID:11595941)
RGD
PMID:11595941
NCBI chr 1:202,643,009...202,652,059
Ensembl chr 1:202,643,038...202,651,824
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Cd9
CD9 molecule
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:10634790), (PMID:10634791), (PMID:10700183), (PMID:21690351) GO_REF:0000107 (PMID:14575715)
UniProt RGD Ensembl
PMID:10634790 PMID:10634791 PMID:10700183 PMID:14575715 PMID:21690351
GO_REF:0000024 GO_REF:0000107
NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
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Dcst1
DC-STAMP domain containing 1
involved_in acts_upstream_of_or_within
ISO
(PMID:33871360) (PMID:35393517)
RGD
PMID:33871360 PMID:35393517
NCBI chr 2:174,765,203...174,784,023
Ensembl chr 2:174,765,350...174,781,806
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Dcst2
DC-STAMP domain containing 2
acts_upstream_of_or_within involved_in
ISO
(PMID:35393517) (PMID:33871360)
RGD
PMID:33871360 PMID:35393517
NCBI chr 2:174,781,806...174,795,834
Ensembl chr 2:174,781,902...174,795,832
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Eqtn
equatorin
involved_in acts_upstream_of_or_within
IEA ISO IBA
GO_REF:0000002 (PMID:9674989) GO_REF:0000033
InterPro RGD GO_Central
PMID:9674989
GO_REF:0000002 GO_REF:0000033
NCBI chr 5:109,734,495...109,762,048
Ensembl chr 5:109,728,999...109,761,840
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Folr1
folate receptor alpha
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667
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Folr2
folate receptor beta
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724
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Frey1
Frey regulator of sperm-oocyte fusion 1
involved_in acts_upstream_of_or_within
IBA ISO
GO_REF:0000033 (PMID:36787362) (PMID:35960805), (PMID:36050562)
GO_Central RGD
PMID:35960805 PMID:36050562 PMID:36787362
GO_REF:0000033
NCBI chr 3:78,354,303...78,355,055
Ensembl chr 3:78,354,303...78,355,055
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Glipr1l1
GLIPR1 like 1
involved_in
ISO
(PMID:31672133)
RGD
PMID:31672133
NCBI chr 7:47,550,637...47,577,611
Ensembl chr 7:47,550,631...47,577,617
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Hyal5
hyaluronoglucosaminidase 5
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 4:53,341,105...53,412,280
Ensembl chr 4:53,343,475...53,370,785
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Itga3
integrin subunit alpha 3
NOT|acts_upstream_of_or_within
ISO
MGI:1857792 (PMID:12591243)
RGD
PMID:12591243
NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
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Izumo1
izumo sperm-oocyte fusion 1
involved_in
ISO IBA ISS
(PMID:15759005) (PMID:15759005), (PMID:24739963), (PMID:31672133), (PMID:35960805) GO_REF:0000033 GO_REF:0000024
RGD GO_Central UniProt
PMID:15759005 PMID:24739963 PMID:31672133 PMID:35960805
GO_REF:0000024 GO_REF:0000033
NCBI chr 1:96,090,817...96,096,893
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Izumo1r
IZUMO1 receptor, JUNO
involved_in
IBA ISS ISO
GO_REF:0000033 GO_REF:0000024 (PMID:30517645) (PMID:24739963), (PMID:27416963)
GO_Central UniProt RGD
PMID:24739963 PMID:27416963 PMID:30517645
GO_REF:0000024 GO_REF:0000033
NCBI chr 8:11,744,384...11,748,131
Ensembl chr 8:11,725,863...11,748,465
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Llcfc1
LLLL and CFNLAS motif containing 1
involved_in
IBA ISO
GO_REF:0000033 (PMID:32393636)
GO_Central RGD
PMID:32393636
GO_REF:0000033
NCBI chr 4:70,566,206...70,567,592
Ensembl chr 4:70,566,295...70,567,586
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Lyzl4
lysozyme-like 4
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 8:121,248,129...121,255,366
Ensembl chr 8:121,248,168...121,255,353
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Lyzl6
lysozyme-like 6
involved_in
ISO IBA
(PMID:24013621) GO_REF:0000033
RGD GO_Central
PMID:24013621
GO_REF:0000033
NCBI chr10:88,544,342...88,549,177
Ensembl chr10:88,544,342...88,549,177
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Spaca3
sperm acrosome associated 3
involved_in
ISO IBA
(PMID:15982649) GO_REF:0000033
RGD GO_Central
PMID:15982649
GO_REF:0000033
NCBI chr10:65,850,618...65,858,090
Ensembl chr10:65,854,893...65,858,094
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Spaca5
sperm acrosome associated 5
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr X:918,817...922,000
Ensembl chr X:918,817...922,049
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Spaca6
sperm acrosome associated 6
involved_in acts_upstream_of_or_within
IBA ISO
GO_REF:0000033 (PMID:32210282), (PMID:32393636) MGI:5514186 (PMID:24275887)
GO_Central RGD
PMID:24275887 PMID:32210282 PMID:32393636
GO_REF:0000033
NCBI chr 1:58,672,128...58,689,309
Ensembl chr 1:58,677,797...58,688,562
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Spam1
sperm adhesion molecule 1
TAS
RGD
PMID:8914077
RGD:634179
NCBI chr 4:53,302,745...53,312,913
Ensembl chr 4:53,302,745...53,312,908
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Spata46
spermatogenesis associated 46
involved_in
ISO
(PMID:27488028)
RGD
PMID:27488028
NCBI chr13:82,541,183...82,544,808
Ensembl chr13:82,541,183...82,544,808
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Spesp1
sperm equatorial segment protein 1
involved_in acts_upstream_of_or_within
IEA ISO IBA
GO_REF:0000002 MGI:4838302 (PMID:20375058) GO_REF:0000033
InterPro RGD GO_Central
PMID:20375058
GO_REF:0000002 GO_REF:0000033
NCBI chr 8:62,751,313...62,766,657
Ensembl chr 8:62,751,297...62,766,718
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Sppl2c
signal peptide peptidase like 2C
involved_in
ISO
(PMID:35960805)
RGD
PMID:35960805
NCBI chr10:89,095,279...89,097,487
Ensembl chr10:89,095,261...89,098,580
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Tmem95
transmembrane protein 95
involved_in
IBA ISO
GO_REF:0000033 (PMID:32393636), (PMID:32484434), (PMID:34982145) (PMID:36161911)
GO_Central RGD
PMID:32393636 PMID:32484434 PMID:34982145 PMID:36161911
GO_REF:0000033
NCBI chr10:54,599,799...54,601,746
Ensembl chr10:54,599,800...54,601,790
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Tpst2
tyrosylprotein sulfotransferase 2
acts_upstream_of_or_within
ISO
MGI:3512111 (PMID:21339297)
RGD
PMID:21339297
NCBI chr12:44,321,875...44,363,892
Ensembl chr12:44,321,875...44,362,329
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Wdr54
WD repeat domain 54
involved_in
IMP
PMID:37951137
UniProt
PMID:37951137
RGD:408345208
NCBI chr 4:115,654,968...115,677,979
Ensembl chr 4:115,654,968...115,661,562
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