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ONTOLOGY REPORT - ANNOTATIONS

Term:sperm-egg recognition
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Accession:GO:0035036 term browser browse the term
Definition:The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization.


show annotations for term's descendants           Sort by:
sperm-egg recognition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd9 CD9 molecule involved_in ISS
ISO		 GO_REF:0000024
(MGI:1351540|PMID:10634790), (MGI:1351541|PMID:10634791), (MGI:5056242|PMID:21690351)		 UniProt
RGD		 PMID:10634790 PMID:10634791 PMID:21690351 GO_REF:0000024 MGI:1351540 MGI:1351541 MGI:5056242 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Dcst1 DC-STAMP domain containing 1 involved_in ISO (MGI:6694748|PMID:33871360) RGD PMID:33871360 MGI:6694748 NCBI chr 2:174,765,203...174,784,023
Ensembl chr 2:174,765,350...174,781,806 		JBrowse link
G Dcst2 DC-STAMP domain containing 2 involved_in ISO (MGI:6694748|PMID:33871360) RGD PMID:33871360 MGI:6694748 NCBI chr 2:174,781,806...174,795,834
Ensembl chr 2:174,781,902...174,795,832 		JBrowse link
G Folr1 folate receptor alpha involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:156,219,460...156,238,436
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Folr2 folate receptor beta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:156,200,044...156,218,380
Ensembl chr 1:156,200,060...156,205,724 		JBrowse link
G Frey1 Frey regulator of sperm-oocyte fusion 1 involved_in ISO (MGI:7332329|PMID:35960805), (MGI:7338896|PMID:36050562) RGD PMID:35960805 PMID:36050562 MGI:7332329 MGI:7338896 NCBI chr 3:78,354,303...78,355,055
Ensembl chr 3:78,354,303...78,355,055 		JBrowse link
G Izumo1 izumo sperm-oocyte fusion 1 involved_in ISS
ISO
IBA		 GO_REF:0000024
(MGI:5568137|PMID:24739963), (MGI:7332329|PMID:35960805)
PMID:21873635		 UniProt
RGD		 PMID:24739963 PMID:35960805 PMID:21873635 GO_REF:0000024 MGI:5568137 MGI:7332329, RGD:13792537 NCBI chr 1:96,090,817...96,096,893 JBrowse link
G Izumo1r IZUMO1 receptor, JUNO involved_in IBA
ISO		 PMID:21873635
(MGI:5568137|PMID:24739963), (MGI:5896483|PMID:27416963)		 RGD PMID:24739963 PMID:27416963 PMID:21873635 MGI:5568137 MGI:5896483, RGD:13792537 NCBI chr 8:11,744,383...11,746,872
Ensembl chr 8:11,725,863...11,748,465 		JBrowse link
G Spaca3 sperm acrosome associated 3 acts_upstream_of_or_within ISO (MGI:3588938|PMID:15982649) RGD PMID:15982649 MGI:3588938 NCBI chr10:65,850,535...65,858,094
Ensembl chr10:65,854,893...65,858,094 		JBrowse link
G Spaca4 sperm acrosome associated 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:96,195,514...96,196,187
Ensembl chr 1:96,195,315...96,196,237 		JBrowse link
G Spesp1 sperm equatorial segment protein 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5643961|PMID:25761597)		 UniProt
RGD		 PMID:25761597 GO_REF:0000024 MGI:5643961 NCBI chr 8:62,751,313...62,766,657
Ensembl chr 8:62,751,297...62,766,718 		JBrowse link
binding of sperm to zona pellucida term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acr acrosin acts_upstream_of_or_within ISO MGI:1888530|MGI:96945|MGI:98785 (MGI:3577815|PMID:15685642) RGD PMID:15685642 MGI:3577815 NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474 		JBrowse link
G Adam1a ADAM metallopeptidase domain 1a involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000107
MGI:3052660 (MGI:3052285|PMID:15194697)		 Ensembl
RGD		 PMID:15194697 PMID:21873635 GO_REF:0000107 MGI:3052285, RGD:13792537 NCBI chr12:35,017,433...35,020,300
Ensembl chr12:35,017,315...35,020,311 		JBrowse link
G Adam1b a disintegrin and metallopeptidase domain 1b involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr12:35,037,488...35,040,185
Ensembl chr12:35,037,343...35,041,082 		JBrowse link
G Adam2 ADAM metallopeptidase domain 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:40,242,783...40,284,025
Ensembl chr15:40,242,783...40,283,952 		JBrowse link
G Adam32 ADAM metallopeptidase domain 32 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,102,384...67,212,163
Ensembl chr16:67,102,320...67,212,161 		JBrowse link
G Adam3a ADAM metallopeptidase domain 3A involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:2156167|MGI:6358812 (MGI:3052285|PMID:15194697), (MGI:3611697|PMID:16330764), (MGI:6452340|PMID:32529245)		 RGD PMID:15194697 PMID:16330764 PMID:32529245 PMID:21873635 MGI:3052285 MGI:3611697 MGI:6452340, RGD:13792537 NCBI chr16:67,299,949...67,349,970
Ensembl chr16:67,299,949...67,349,968 		JBrowse link
G Adam5 ADAM metallopeptidase domain 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:67,223,095...67,298,733
Ensembl chr16:67,223,143...67,298,737 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A involved_in ISO (PMID:23355646) RGD PMID:23355646 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Arsa arylsulfatase A acts_upstream_of_or_within ISO (MGI:2181942|PMID:12080020) RGD PMID:12080020 MGI:2181942 NCBI chr 7:120,542,788...120,547,577
Ensembl chr 7:120,543,362...120,548,783 		JBrowse link
G Atp8b3 ATPase phospholipid transporting 8B3 acts_upstream_of_or_within ISO MGI:3039498 (MGI:3037203|PMID:14975727) RGD PMID:14975727 MGI:3037203 NCBI chr 7:9,175,544...9,195,449
Ensembl chr 7:9,175,391...9,195,442 		JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2178779|PR:P10761 (MGI:1098917|PMID:9374408), (MGI:68417|PMID:8089187)		 Ensembl
RGD		 PMID:8089187 PMID:9374408 GO_REF:0000107 MGI:1098917 MGI:68417 NCBI chr 5:55,935,614...55,982,461
Ensembl chr 5:55,935,615...55,982,461 		JBrowse link
G C4bpa complement component 4 binding protein, alpha acts_upstream_of_or_within
involved_in		 ISO (MGI:5295912|PMID:21880732), (MGI:74309|PMID:7604284)
(MGI:4942258|PMID:11417900)		 RGD PMID:7604284 PMID:11417900 PMID:21880732 MGI:4942258 MGI:5295912 MGI:74309 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205 		JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 acts_upstream_of_or_within ISO (MGI:5295912|PMID:21880732) RGD PMID:21880732 MGI:5295912 NCBI chr 7:52,692,725...52,705,478
Ensembl chr 7:52,692,725...52,706,944 		JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 acts_upstream_of_or_within ISO (MGI:5295912|PMID:21880732) RGD PMID:21880732 MGI:5295912 NCBI chr 2:173,765,792...173,790,353
Ensembl chr 2:173,765,698...173,790,757 		JBrowse link
G Cct4 chaperonin containing TCP1 subunit 4 acts_upstream_of_or_within ISO (MGI:5295912|PMID:21880732) RGD PMID:21880732 MGI:5295912 NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 acts_upstream_of_or_within ISO (MGI:5295912|PMID:21880732) RGD PMID:21880732 MGI:5295912 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930 		JBrowse link
G Cct6a chaperonin containing TCP1 subunit 6A acts_upstream_of_or_within ISO (MGI:5295912|PMID:21880732) RGD PMID:21880732 MGI:5295912 NCBI chr12:26,872,736...26,883,125
Ensembl chr12:26,872,574...26,883,337 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 acts_upstream_of_or_within ISO (MGI:5295912|PMID:21880732) RGD PMID:21880732 MGI:5295912 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 acts_upstream_of_or_within ISO (MGI:5295912|PMID:21880732) RGD PMID:21880732 MGI:5295912 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079 		JBrowse link
G Clgn calmegin acts_upstream_of_or_within ISO MGI:2156041 (MGI:2154902|PMID:11784061), (MGI:892217|PMID:9177349) RGD PMID:9177349 PMID:11784061 MGI:2154902 MGI:892217 NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758 		JBrowse link
G Crisp1 cysteine-rich secretory protein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:5431546 (MGI:5429850|PMID:21865554)		 RGD PMID:21865554 PMID:21873635 MGI:5429850, RGD:13792537 NCBI chr 9:20,741,775...20,768,796
Ensembl chr 9:20,741,777...20,768,796 		JBrowse link
G Fetub fetuin B involved_in IBA
ISO
ISS		 PMID:21873635
(MGI:5488517|PMID:23562279)
GO_REF:0000024		 RGD
UniProt		 PMID:23562279 PMID:21873635 GO_REF:0000024 MGI:5488517, RGD:13792537 NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135 		JBrowse link
G Glipr1l1 GLIPR1 like 1 acts_upstream_of_or_within ISO (MGI:64089|PMID:8260598) RGD PMID:8260598 MGI:64089 NCBI chr 7:47,550,637...47,577,611
Ensembl chr 7:47,550,631...47,577,617 		JBrowse link
G Gml glycosylphosphatidylinositol anchored molecule like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:106,683,749...106,712,802
Ensembl chr 7:106,683,753...106,686,372 		JBrowse link
G H1f6 H1.6 linker histone, cluster member acts_upstream_of_or_within ISO MGI:87884|MGI:96945|MGI:98785 (MGI:3577815|PMID:15685642) RGD PMID:15685642 MGI:3577815 NCBI chr17:41,427,365...41,428,109
Ensembl chr17:41,427,323...41,428,119 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A acts_upstream_of_or_within ISO (MGI:5295912|PMID:21880732) RGD PMID:21880732 MGI:5295912 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like acts_upstream_of_or_within ISO (MGI:5295912|PMID:21880732) RGD PMID:21880732 MGI:5295912 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571 		JBrowse link
G Ly6k lymphocyte antigen 6 family member K acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:5618096 (MGI:5570511|PMID:24501175)
PMID:21873635		 RGD PMID:24501175 PMID:21873635 MGI:5570511, RGD:13792537
G Pcsk4 proprotein convertase subtilisin/kexin type 4 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
MGI:2665512 (MGI:3619873|PMID:16371590)		 UniProt
Ensembl
RGD		 PMID:16371590 GO_REF:0000024 GO_REF:0000107 MGI:3619873 NCBI chr 7:9,381,366...9,389,589
Ensembl chr 7:9,381,361...9,389,585 		JBrowse link
G Prss37 serine protease 37 acts_upstream_of_or_within ISO MGI:5520954 (MGI:5516557|PMID:23553430) RGD PMID:23553430 MGI:5516557 NCBI chr 4:69,322,977...69,334,555
Ensembl chr 4:69,322,977...69,334,555 		JBrowse link
G Prss55 serine protease 55 involved_in ISO (MGI:6323546|PMID:30032357) RGD PMID:30032357 MGI:6323546 NCBI chr15:38,297,674...38,345,059
Ensembl chr15:38,312,982...38,323,103 		JBrowse link
G Smcp sperm mitochondria-associated cysteine-rich protein acts_upstream_of_or_within ISO MGI:1888530|MGI:87884|MGI:98785 (MGI:3577815|PMID:15685642) RGD PMID:15685642 MGI:3577815 NCBI chr 2:178,160,948...178,165,951
Ensembl chr 2:178,160,127...178,166,001 		JBrowse link
G Spa17 sperm autoantigenic protein 17 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 8:37,307,432...37,318,645
Ensembl chr 8:37,307,557...37,318,639 		JBrowse link
G Tcp1 t-complex 1 acts_upstream_of_or_within ISO (MGI:5295912|PMID:21880732) RGD PMID:21880732 MGI:5295912 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839 		JBrowse link
G Tex101 testis expressed 101 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(MGI:5492179|PMID:23633567)
PMID:21873635		 UniProt
Ensembl
RGD		 PMID:23633567 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5492179, RGD:13792537 NCBI chr 1:80,255,076...80,259,442
Ensembl chr 1:80,255,076...80,259,442 		JBrowse link
G Tmprss12 transmembrane serine protease 12 acts_upstream_of_or_within ISO MGI:6455010 (MGI:6452340|PMID:32529245) RGD PMID:32529245 MGI:6452340 NCBI chr 7:131,433,158...131,445,806
Ensembl chr 7:131,433,484...131,445,791 		JBrowse link
G Tnp2 transition protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1888530|MGI:87884|MGI:96945 (MGI:3577815|PMID:15685642)		 Ensembl
RGD		 PMID:15685642 GO_REF:0000107 MGI:3577815 NCBI chr10:4,879,812...4,880,540
Ensembl chr10:4,879,812...4,880,538 		JBrowse link
G Ubap2l ubiquitin associated protein 2-like involved_in ISO (PMID:19945174) RGD PMID:19945174 NCBI chr 2:175,438,703...175,494,085
Ensembl chr 2:175,438,703...175,493,998 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 involved_in ISO (PMID:23355646) RGD PMID:23355646 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553 		JBrowse link
G Zan zonadhesin acts_upstream_of_or_within ISO (PMID:7592795) RGD PMID:7592795 NCBI chr12:19,215,018...19,322,789
Ensembl chr12:19,215,102...19,271,240 		JBrowse link
G Zp1 zona pellucida glycoprotein 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:207,560,881...207,567,261
Ensembl chr 1:207,560,881...207,567,261 		JBrowse link
G Zp2 zona pellucida glycoprotein 2 involved_in
acts_upstream_of_or_within		 ISS
IBA
ISO
IEA		 PMID:22472438
PMID:21873635
(MGI:5427546|PMID:22472438)
(MGI:2154647|PMID:11739644)
GO_REF:0000107		 RGD
Ensembl		 PMID:11739644 PMID:22472438 PMID:22472438 PMID:21873635 GO_REF:0000107 MGI:2154647 MGI:5427546, RGD:8554097, RGD:13792537 NCBI chr 1:174,513,507...174,525,288
Ensembl chr 1:174,513,511...174,525,288 		JBrowse link
G Zp3 zona pellucida glycoprotein 3 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO
ISS		 GO_REF:0000104
PMID:21873635
PR:P15535 (MGI:1098917|PMID:9374408), (MGI:2154647|PMID:11739644)
UniProtKB:P21754 (MGI:2181829|PMID:9609824), (MGI:4942258|PMID:11417900)
GO_REF:0000024
(PMID:12052239)
UniProtKB:P10761 (PMID:19004505), (PMID:19246320), (PMID:19700799), (PMID:9609824)		 UniProt
RGD		 PMID:9374408 PMID:9609824 PMID:11417900 PMID:11739644 PMID:12052239 More... GO_REF:0000024 GO_REF:0000104 MGI:1098917 MGI:2154647 MGI:2181829 MGI:4942258, RGD:13792537 NCBI chr12:20,690,547...20,697,513
Ensembl chr12:20,690,547...20,697,513 		JBrowse link
G Zp3r zona pellucida 3 receptor IMP RGD PMID:12737520 RGD:1299568 NCBI chr13:42,019,998...42,064,836
Ensembl chr13:42,020,018...42,064,812 		JBrowse link
G Zp4 zona pellucida glycoprotein 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:59,005,649...59,012,202
Ensembl chr17:59,005,649...59,012,202 		JBrowse link
G Zpbp zona pellucida binding protein acts_upstream_of_or_within
involved_in		 ISO
IBA		 (MGI:5295912|PMID:21880732)
PMID:21873635		 RGD PMID:21880732 PMID:21873635 MGI:5295912, RGD:13792537 NCBI chr14:85,830,971...86,030,778
Ensembl chr14:85,833,548...86,033,095 		JBrowse link
G Zpbp2 zona pellucida binding protein 2 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 PMID:21873635
GO_REF:0000002
(MGI:5295912|PMID:21880732)		 InterPro
RGD		 PMID:21880732 PMID:21873635 GO_REF:0000002 MGI:5295912, RGD:13792537 NCBI chr10:83,558,772...83,567,511
Ensembl chr10:83,559,016...83,567,508 		JBrowse link
negative regulation of binding of sperm to zona pellucida term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Astl astacin like metalloendopeptidase involved_in ISO (MGI:5427546|PMID:22472438) RGD PMID:22472438 MGI:5427546 NCBI chr 3:114,563,135...114,580,295
Ensembl chr 3:114,563,135...114,578,868 		JBrowse link
G Zp3 zona pellucida glycoprotein 3 involved_in ISO
ISS		 (PMID:18667750)
GO_REF:0000024		 RGD
UniProt		 PMID:18667750 GO_REF:0000024 NCBI chr12:20,690,547...20,697,513
Ensembl chr12:20,690,547...20,697,513 		JBrowse link
G Zp4 zona pellucida glycoprotein 4 involved_in ISO
IEA		 (PMID:18667750)
GO_REF:0000107		 RGD
Ensembl		 PMID:18667750 GO_REF:0000107 NCBI chr17:59,005,649...59,012,202
Ensembl chr17:59,005,649...59,012,202 		JBrowse link
regulation of binding of sperm to zona pellucida term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Paep progestagen associated endometrial protein involved_in ISO (PMID:17192260) RGD PMID:17192260 NCBI chr 3:8,531,136...8,534,430
Ensembl chr 3:8,531,138...8,534,430 		JBrowse link
G Zan zonadhesin acts_upstream_of_or_within ISO (MGI:4838734|PMID:20529856) RGD PMID:20529856 MGI:4838734 NCBI chr12:19,215,018...19,322,789
Ensembl chr12:19,215,102...19,271,240 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    reproductive process 1779
      sperm-egg recognition 60
        binding of sperm to zona pellucida + 49
Path 2
Term Annotations click to browse term
  biological_process 19748
    reproduction 1789
      sexual reproduction 1109
        fertilization 211
          single fertilization 162
            sperm-egg recognition 60
              binding of sperm to zona pellucida + 49
paths to the root