UNC13B (unc-13 homolog B) - Rat Genome Database

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Gene: UNC13B (unc-13 homolog B) Pan paniscus
Analyze
Symbol: UNC13B
Name: unc-13 homolog B
RGD ID: 11739172
Description: ENCODES a protein that exhibits GTP-dependent protein binding (ortholog); syntaxin binding (ortholog); INVOLVED IN acrosomal vesicle exocytosis (ortholog); cellular response to glucose stimulus (ortholog); chemical synaptic transmission (ortholog); ASSOCIATED WITH acromesomelic dysplasia, Maroteaux type (ortholog); anauxetic dysplasia (ortholog); autosomal recessive distal hereditary motor neuronopathy 2 (ortholog); FOUND IN calyx of Held (ortholog); cytosol (ortholog); early phagosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21189,184,307 - 89,431,211 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1989,190,246 - 89,437,207 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0935,011,350 - 35,255,148 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1935,817,353 - 36,059,895 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl935,817,353 - 36,059,894 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
UNC13B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21189,184,307 - 89,431,211 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1989,190,246 - 89,437,207 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0935,011,350 - 35,255,148 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1935,817,353 - 36,059,895 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl935,817,353 - 36,059,894 (+)Ensemblpanpan1.1panPan2
UNC13B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38935,162,009 - 35,405,335 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl935,161,992 - 35,405,338 (+)EnsemblGRCh38hg38GRCh38
GRCh37935,162,006 - 35,405,332 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,151,989 - 35,395,332 (+)NCBINCBI36Build 36hg18NCBI36
Build 34935,152,058 - 35,395,331NCBI
Celera935,093,995 - 35,337,320 (+)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef935,117,517 - 35,359,509 (+)NCBIHuRef
CHM1_1935,161,866 - 35,405,103 (+)NCBICHM1_1
T2T-CHM13v2.0935,181,209 - 35,424,479 (+)NCBIT2T-CHM13v2.0
Unc13b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39443,046,193 - 43,264,873 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl443,058,953 - 43,264,871 (+)EnsemblGRCm39 Ensembl
GRCm38443,046,193 - 43,264,873 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl443,058,953 - 43,264,871 (+)EnsemblGRCm38mm10GRCm38
MGSCv37443,071,856 - 43,277,759 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36443,080,053 - 43,285,973 (+)NCBIMGSCv36mm8
Celera443,089,000 - 43,293,387 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map423.0NCBI
Unc13b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8562,084,809 - 62,299,884 (+)NCBIGRCr8
mRatBN7.2557,288,999 - 57,504,110 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl557,289,227 - 57,502,926 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx559,262,249 - 59,477,176 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0561,081,066 - 61,295,990 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0561,066,236 - 61,280,959 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0558,505,449 - 58,714,396 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl558,505,500 - 58,715,576 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0563,030,715 - 63,240,229 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4559,551,928 - 59,768,901 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1559,716,002 - 59,769,080 (+)NCBI
Celera555,876,984 - 56,089,901 (+)NCBICelera
Cytogenetic Map5q22NCBI
UNC13B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11151,707,968 - 51,941,148 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1151,708,302 - 51,940,955 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1150,276,777 - 50,508,946 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01152,773,675 - 53,006,449 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1152,773,727 - 53,006,464 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11151,388,636 - 51,551,200 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01151,302,640 - 51,534,710 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01152,004,520 - 52,236,429 (+)NCBIUU_Cfam_GSD_1.0
Unc13b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947166,680,023 - 166,822,285 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365243,320,859 - 3,369,865 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UNC13B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1235,918,747 - 236,158,098 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11235,918,751 - 236,158,098 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21263,840,380 - 263,877,078 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103219228
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11245,230,661 - 45,461,934 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1245,230,659 - 45,461,339 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603842,341,062 - 42,574,219 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Unc13b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624915327,401 - 531,886 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624915327,633 - 530,522 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Ensembl Acc Id: ENSPPAT00000050413   ⟹   ENSPPAP00000027571
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl935,817,353 - 36,059,894 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050423   ⟹   ENSPPAP00000027581
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl935,817,668 - 36,058,588 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050432   ⟹   ENSPPAP00000027590
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl935,884,736 - 36,058,588 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050436   ⟹   ENSPPAP00000027594
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl935,884,736 - 36,058,588 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050439   ⟹   ENSPPAP00000027598
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl936,008,216 - 36,058,588 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050447   ⟹   ENSPPAP00000027605
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl936,008,216 - 36,058,588 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000050452   ⟹   ENSPPAP00000027610
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl936,026,988 - 36,058,588 (+)Ensembl
RefSeq Acc Id: XM_003829825   ⟹   XP_003829873
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21189,184,307 - 89,429,959 (-)NCBI
NHGRI_mPanPan1989,190,246 - 89,434,221 (-)NCBI
Mhudiblu_PPA_v0935,011,362 - 35,255,145 (+)NCBI
PanPan1.1935,817,376 - 36,059,892 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003829826   ⟹   XP_003829874
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21189,184,307 - 89,429,958 (-)NCBI
NHGRI_mPanPan1989,190,246 - 89,434,221 (-)NCBI
Mhudiblu_PPA_v0935,011,362 - 35,255,148 (+)NCBI
PanPan1.1935,817,353 - 36,059,895 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008955225   ⟹   XP_008953473
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21189,184,307 - 89,429,961 (-)NCBI
NHGRI_mPanPan1989,190,246 - 89,434,221 (-)NCBI
Mhudiblu_PPA_v0935,011,362 - 35,255,148 (+)NCBI
PanPan1.1935,817,353 - 36,059,894 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034967385   ⟹   XP_034823276
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21189,184,307 - 89,245,881 (-)NCBI
NHGRI_mPanPan1989,190,246 - 89,251,820 (-)NCBI
Mhudiblu_PPA_v0935,193,771 - 35,255,148 (+)NCBI
RefSeq Acc Id: XM_034967386   ⟹   XP_034823277
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21189,184,307 - 89,245,882 (-)NCBI
NHGRI_mPanPan1989,190,246 - 89,251,821 (-)NCBI
Mhudiblu_PPA_v0935,193,563 - 35,255,148 (+)NCBI
RefSeq Acc Id: XM_055092057   ⟹   XP_054948032
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21189,184,307 - 89,429,960 (-)NCBI
NHGRI_mPanPan1989,190,246 - 89,434,221 (-)NCBI
RefSeq Acc Id: XM_055092058   ⟹   XP_054948033
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21189,184,307 - 89,431,211 (-)NCBI
NHGRI_mPanPan1989,190,246 - 89,437,207 (-)NCBI
RefSeq Acc Id: XM_057298717   ⟹   XP_057154700
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21189,184,307 - 89,245,882 (-)NCBI
NHGRI_mPanPan1989,190,246 - 89,251,821 (-)NCBI
RefSeq Acc Id: XP_003829874   ⟸   XM_003829826
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BH08 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008953473   ⟸   XM_008955225
- Peptide Label: isoform X7
- UniProtKB: A0A2R9BH08 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003829873   ⟸   XM_003829825
- Peptide Label: isoform X6
- UniProtKB: A0A2R9BH08 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034823277   ⟸   XM_034967386
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BD80 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034823276   ⟸   XM_034967385
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BD80 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000027571   ⟸   ENSPPAT00000050413
Ensembl Acc Id: ENSPPAP00000027581   ⟸   ENSPPAT00000050423
Ensembl Acc Id: ENSPPAP00000027594   ⟸   ENSPPAT00000050436
Ensembl Acc Id: ENSPPAP00000027590   ⟸   ENSPPAT00000050432
Ensembl Acc Id: ENSPPAP00000027605   ⟸   ENSPPAT00000050447
Ensembl Acc Id: ENSPPAP00000027598   ⟸   ENSPPAT00000050439
Ensembl Acc Id: ENSPPAP00000027610   ⟸   ENSPPAT00000050452
RefSeq Acc Id: XP_054948033   ⟸   XM_055092058
- Peptide Label: isoform X8
- UniProtKB: A0A2R9BLQ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054948032   ⟸   XM_055092057
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BH08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_057154700   ⟸   XM_057298717
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BD80 (UniProtKB/TrEMBL)
Protein Domains
C2   MHD1   MHD2   Phorbol-ester/DAG-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036786 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050413.1 UniProtKB/TrEMBL
  ENSPPAT00000050423.1 UniProtKB/TrEMBL
  ENSPPAT00000050432.1 UniProtKB/TrEMBL
  ENSPPAT00000050436.1 UniProtKB/TrEMBL
  ENSPPAT00000050439.1 UniProtKB/TrEMBL
  ENSPPAT00000050447.1 UniProtKB/TrEMBL
  ENSPPAT00000050452.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.357.50 UniProtKB/TrEMBL
  1.20.58.1100 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  MUN_dom UniProtKB/TrEMBL
  Munc13_1 UniProtKB/TrEMBL
  Munc13_dom-2 UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  Unc-13 UniProtKB/TrEMBL
  Unc-13_C2B UniProtKB/TrEMBL
NCBI Gene UNC13B ENTREZGENE
PANTHER PROTEIN UNC-13 HOMOLOG B UniProtKB/TrEMBL
  PTHR10480 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  DUF1041 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
PRINTS C2DOMAIN UniProtKB/TrEMBL
PROSITE MHD1 UniProtKB/TrEMBL
  MHD2 UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART DUF1041 UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A2R9BD80 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BDA6_PANPA UniProtKB/TrEMBL
  A0A2R9BH08 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BH13_PANPA UniProtKB/TrEMBL
  A0A2R9BLQ9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BLS9_PANPA UniProtKB/TrEMBL
  A0A2R9BLT7_PANPA UniProtKB/TrEMBL