DCST1 (DC-STAMP domain containing 1) - Rat Genome Database

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Gene: DCST1 (DC-STAMP domain containing 1) Pan paniscus
Analyze
Symbol: DCST1
Name: DC-STAMP domain containing 1
RGD ID: 11692826
Description: ENCODES a protein that exhibits ubiquitin protein ligase activity (inferred); zinc ion binding (inferred); INVOLVED IN fusion of sperm to egg plasma membrane involved in single fertilization (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease type 2 (ortholog); gastrointestinal stromal tumor (ortholog); immunodeficiency 42 (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DC-STAMP domain-containing protein 1; E3 ubiquitin-protein ligase DCST1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2194,790,000 - 94,807,221 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,522,036 - 94,539,274 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01130,381,851 - 130,398,975 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,991,485 - 134,008,614 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1133,991,485 - 134,008,614 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
DCST1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2194,790,000 - 94,807,221 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,522,036 - 94,539,274 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01130,381,851 - 130,398,975 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,991,485 - 134,008,614 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1133,991,485 - 134,008,614 (+)Ensemblpanpan1.1panPan2
DCST1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381155,033,806 - 155,050,930 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1155,033,824 - 155,050,930 (+)EnsemblGRCh38hg38GRCh38
GRCh371155,006,282 - 155,023,406 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361153,272,924 - 153,290,030 (+)NCBINCBI36Build 36hg18NCBI36
Celera1128,077,323 - 128,094,429 (+)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1126,368,275 - 126,385,407 (+)NCBIHuRef
CHM1_11156,402,087 - 156,419,230 (+)NCBICHM1_1
T2T-CHM13v2.01154,173,182 - 154,190,315 (+)NCBIT2T-CHM13v2.0
Dcst1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39389,257,526 - 89,272,560 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl389,257,526 - 89,272,560 (-)EnsemblGRCm39 Ensembl
GRCm38389,350,219 - 89,365,253 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl389,350,219 - 89,365,253 (-)EnsemblGRCm38mm10GRCm38
MGSCv37389,154,157 - 89,169,161 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36389,436,018 - 89,451,180 (-)NCBIMGSCv36mm8
Celera389,385,278 - 89,400,282 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.08NCBI
Dcst1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,063,083 - 177,079,914 (-)NCBIGRCr8
mRatBN7.22174,765,203 - 174,784,023 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2174,765,350 - 174,781,806 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.02188,672,549 - 188,690,004 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2188,672,405 - 188,689,392 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02208,082,762 - 208,105,311 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,537,936 - 181,560,124 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12181,488,041 - 181,510,230 (-)NCBI
Celera2168,706,913 - 168,724,388 (-)NCBICelera
Cytogenetic Map2q34NCBI
Dcst1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555451,530,062 - 1,545,139 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555451,529,926 - 1,545,459 (+)NCBIChiLan1.0ChiLan1.0
DCST1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1742,443,787 - 42,457,361 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl742,428,113 - 42,457,062 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha741,933,862 - 41,947,618 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0742,312,690 - 42,326,476 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl742,312,821 - 42,325,942 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1742,092,400 - 42,106,183 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0742,146,233 - 42,160,016 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0742,429,578 - 42,443,361 (-)NCBIUU_Cfam_GSD_1.0
Dcst1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505825,540,880 - 25,556,071 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365804,571,319 - 4,586,394 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365804,571,349 - 4,586,459 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCST1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl494,748,429 - 94,768,452 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1494,748,430 - 94,768,322 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24103,530,040 - 103,536,291 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCST1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1208,779,692 - 8,797,327 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl208,779,754 - 8,797,306 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660388,114,042 - 8,131,674 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dcst1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248852,451,404 - 2,465,397 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248852,451,247 - 2,465,459 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000039981   ⟹   ENSPPAP00000017279
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1133,991,485 - 134,006,949 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000039983   ⟹   ENSPPAP00000017281
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1133,991,499 - 134,008,614 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000039988   ⟹   ENSPPAP00000017286
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1133,991,552 - 134,008,552 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000039991   ⟹   ENSPPAP00000017289
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1134,003,907 - 134,008,552 (+)Ensembl
RefSeq Acc Id: XM_055101024   ⟹   XP_054956999
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2194,790,013 - 94,807,217 (-)NCBI
NHGRI_mPanPan1194,522,049 - 94,539,270 (-)NCBI
RefSeq Acc Id: XM_055101027   ⟹   XP_054957002
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2194,790,000 - 94,807,221 (-)NCBI
NHGRI_mPanPan1194,522,036 - 94,539,274 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054956999 (Get FASTA)   NCBI Sequence Viewer  
  XP_054957002 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000017279.1
  ENSPPAP00000017281.1
  ENSPPAP00000017286.1
  ENSPPAP00000017289.1
Ensembl Acc Id: ENSPPAP00000017289   ⟸   ENSPPAT00000039991
Ensembl Acc Id: ENSPPAP00000017286   ⟸   ENSPPAT00000039988
Ensembl Acc Id: ENSPPAP00000017281   ⟸   ENSPPAT00000039983
Ensembl Acc Id: ENSPPAP00000017279   ⟸   ENSPPAT00000039981
RefSeq Acc Id: XP_054957002   ⟸   XM_055101027
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AIT4 (UniProtKB/TrEMBL),   A0A2R9AIT8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054956999   ⟸   XM_055101024
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AIT8 (UniProtKB/TrEMBL)
Protein Domains
Dendritic cell-specific transmembrane protein-like   RING-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031720 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000039981.1 UniProtKB/TrEMBL
  ENSPPAT00000039983.1 UniProtKB/TrEMBL
  ENSPPAT00000039988.1 UniProtKB/TrEMBL
  ENSPPAT00000039991.1 UniProtKB/TrEMBL
InterPro CSR-E3_Ligase_Protein UniProtKB/TrEMBL
  DC_STAMP-like UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
NCBI Gene DCST1 ENTREZGENE
PANTHER DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN UniProtKB/TrEMBL
  E3 UBIQUITIN-PROTEIN LIGASE DCST1 UniProtKB/TrEMBL
Pfam DC_STAMP UniProtKB/TrEMBL
PROSITE ZF_RING_2 UniProtKB/TrEMBL
UniProt A0A2R9AIT4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AIT8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AQW9_PANPA UniProtKB/TrEMBL
  A0A2R9AQX8_PANPA UniProtKB/TrEMBL