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mesodermal cell fate commitment - Ontology Report - Rat Genome Database

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ONTOLOGY REPORT - ANNOTATIONS

Term:mesodermal cell fate commitment
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Accession:GO:0001710 term browser browse the term
Definition:The cell differentiation process that results in commitment of a cell to become part of the mesoderm.
Synonyms:exact_synonym: mesoderm cell fate commitment

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mesodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nanog Nanog homeobox acts_upstream_of_or_within ISO
IEA 		MGI:109452 (PMID:16801560)
GO_REF:0000107 		RGD
Ensembl		 PMID:16801560 GO_REF:0000107 NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO
IEA 		(PMID:10742100)
GO_REF:0000107 		RGD
Ensembl		 PMID:10742100 GO_REF:0000107 NCBI chr20:3,227,836...3,232,598
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Smad1 SMAD family member 1 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1919200 (PMID:16801560) 		Ensembl
RGD		 PMID:16801560 GO_REF:0000107 NCBI chr19:45,417,430...45,477,962
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO
IEA 		(PMID:14511481)
GO_REF:0000107 		RGD
Ensembl		 PMID:14511481 GO_REF:0000107 NCBI chr20:29,911,258...29,919,659
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
mesodermal cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO
IEA 		MGI:1857137 (PMID:7657163)
GO_REF:0000107 		RGD
Ensembl		 PMID:7657163 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etv2 ETS variant transcription factor 2 acts_upstream_of_or_within ISO (PMID:18462699) RGD PMID:18462699 NCBI chr 1:95,017,980...95,021,582
Ensembl chr 1:85,890,559...85,893,431 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in ISO (PMID:17785448) RGD PMID:17785448 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Hoxa11 homeobox A11 involved_in ISO
IEA 		(PMID:17785448)
GO_REF:0000107 		RGD
Ensembl		 PMID:17785448 GO_REF:0000107 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232 		JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO 		GO_REF:0000024
(PMID:17785448) 		UniProt
RGD		 PMID:17785448 GO_REF:0000024 NCBI chr 1:253,555,447...253,646,623
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of ISO
IEA 		MGI:98956 (PMID:17462603)
GO_REF:0000107 		RGD
Ensembl		 PMID:17462603 GO_REF:0000107 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Six2 SIX homeobox 2 involved_in IEA
ISO 		GO_REF:0000107
(PMID:17785448) 		Ensembl
RGD		 PMID:17785448 GO_REF:0000107 NCBI chr 6:14,727,756...14,734,219
Ensembl chr 6:8,967,157...8,981,193 		JBrowse link
G Tbx6 T-box transcription factor 6 acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:2447721 (PMID:9490412) 		Ensembl
RGD		 PMID:9490412 GO_REF:0000107 NCBI chr 1:181,387,851...181,392,762
Ensembl chr 1:181,388,684...181,392,593 		JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO
IEA 		(PMID:18593560)
GO_REF:0000107 		RGD
Ensembl		 PMID:18593560 GO_REF:0000107 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO
IEA 		MGI:98956 (PMID:17462603)
GO_REF:0000107 		RGD
Ensembl		 PMID:17462603 GO_REF:0000107 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
paraxial mesodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO MGI:1857865 (PMID:9106663) RGD PMID:9106663 NCBI chr19:66,094,718...66,097,420
Ensembl chr19:49,185,662...49,188,737 		JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:1857489 (PMID:9126297) 		Ensembl
RGD		 PMID:9126297 GO_REF:0000107 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO
IEA 		(PMID:20559569)
GO_REF:0000107 		RGD
Ensembl		 PMID:20559569 GO_REF:0000107 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within IEA
ISO 		GO_REF:0000107
MGI:95522 (PMID:16943278) 		Ensembl
RGD		 PMID:16943278 GO_REF:0000107 NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO
IEA 		MGI:1338938 (PMID:16943278)
GO_REF:0000107 		RGD
Ensembl		 PMID:16943278 GO_REF:0000107 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      cellular developmental process 4838
        cell differentiation 4837
          mesodermal cell differentiation 37
            mesodermal cell fate commitment 18
              axial mesodermal cell fate commitment + 1
              intermediate mesodermal cell fate commitment + 0
              lateral mesodermal cell fate commitment + 2
              mesodermal cell fate determination + 1
              mesodermal cell fate specification + 13
              paraxial mesodermal cell fate commitment + 2
Path 2
Term Annotations click to browse term
  biological_process 20567
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          embryo development 1381
            embryonic morphogenesis 708
              gastrulation 216
                formation of primary germ layer 142
                  mesoderm formation 83
                    mesodermal cell differentiation 37
                      mesodermal cell fate commitment 18
                        axial mesodermal cell fate commitment + 1
                        intermediate mesodermal cell fate commitment + 0
                        lateral mesodermal cell fate commitment + 2
                        mesodermal cell fate determination + 1
                        mesodermal cell fate specification + 13
                        paraxial mesodermal cell fate commitment + 2
paths to the root