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ONTOLOGY REPORT - ANNOTATIONS


Term:mesodermal cell differentiation
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Accession:GO:0048333 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.
Synonyms:exact_synonym: mesoderm cell differentiation


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mesodermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO (MGI:70235|PMID:7799920) RGD PMID:7799920 MGI:70235 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 IEP RGD PMID:7803853 RGD:632663 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Hmga2 high mobility group AT-hook 2 involved_in ISO
ISS
(PMID:17624332)
GO_REF:0000024
RGD
UniProt
PMID:17624332 GO_REF:0000024 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784
JBrowse link
G Inhba inhibin subunit beta A acts_upstream_of_or_within ISO (MGI:70235|PMID:7799920) RGD PMID:7799920 MGI:70235 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Itga2 integrin subunit alpha 2 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481
JBrowse link
G Itga3 integrin subunit alpha 3 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itga8 integrin subunit alpha 8 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510
JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISO
IEA
(PMID:23154389)
GO_REF:0000107
RGD
Ensembl
PMID:23154389 GO_REF:0000107 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb3 integrin subunit beta 3 involved_in ISO (PMID:23154389) RGD PMID:23154389 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Itgb4 integrin subunit beta 4 involved_in ISO
IEA
(PMID:23154389)
GO_REF:0000107
RGD
Ensembl
PMID:23154389 GO_REF:0000107 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
JBrowse link
G Kdm6a lysine demethylase 6A acts_upstream_of_or_within ISO MGI:5448754|MGI:5448825 (MGI:5448135|PMID:22949634) RGD PMID:22949634 MGI:5448135 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062
JBrowse link
G Kdm6b lysine demethylase 6B involved_in ISO (MGI:5574281|PMID:23856522) RGD PMID:23856522 MGI:5574281 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794
JBrowse link
axial mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nodal nodal growth differentiation factor acts_upstream_of_or_within ISO (MGI:2677178|PMID:14511481) RGD PMID:14511481 MGI:2677178 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837
JBrowse link
BMP signaling pathway involved in mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etv2 ETS variant transcription factor 2 acts_upstream_of_or_within ISO (MGI:4415813|PMID:18462699) RGD PMID:18462699 MGI:4415813 NCBI chr 1:85,890,562...85,894,025
Ensembl chr 1:85,890,559...85,893,431
JBrowse link
hemangioblast cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tal1 TAL bHLH transcription factor 1, erythroid differentiation factor acts_upstream_of_or_within ISO MGI:1857254 (MGI:3580923|PMID:15677567), (MGI:3807430|PMID:18550854), (MGI:3838687|PMID:19182774) RGD PMID:15677567 PMID:18550854 PMID:19182774 MGI:3580923 MGI:3807430 MGI:3838687 NCBI chr 5:128,586,776...128,600,976
Ensembl chr 5:128,587,701...128,600,976
JBrowse link
intermediate mesodermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO
ISS
IEA
(PMID:10021330)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:10021330 GO_REF:0000024 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
lateral mesodermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxf1 forkhead box F1 acts_upstream_of_or_within ISO MGI:1929432 (MGI:1928688|PMID:11124112) RGD PMID:11124112 MGI:1928688 NCBI chr19:49,153,729...49,157,741
Ensembl chr19:49,153,699...49,157,738
JBrowse link
mesodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nanog Nanog homeobox acts_upstream_of_or_within ISO MGI:109452 (MGI:3654744|PMID:16801560) RGD PMID:16801560 MGI:3654744 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116
JBrowse link
G Pou5f1 POU class 5 homeobox 1 acts_upstream_of_or_within ISO (MGI:1355046|PMID:10742100) RGD PMID:10742100 MGI:1355046 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Smad1 SMAD family member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1919200 (MGI:3654744|PMID:16801560)
Ensembl
RGD
PMID:16801560 GO_REF:0000107 MGI:3654744 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
JBrowse link
mesodermal cell fate determination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857137 (MGI:76261|PMID:7657163)
Ensembl
RGD
PMID:7657163 GO_REF:0000107 MGI:76261 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483
JBrowse link
G Hoxa11 homeobox A11 involved_in ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232
JBrowse link
G Pax2 paired box 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3768605|PMID:17785448)
UniProt
RGD
PMID:17785448 GO_REF:0000024 MGI:3768605 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321
JBrowse link
G Six2 SIX homeobox 2 involved_in ISO (MGI:3768605|PMID:17785448) RGD PMID:17785448 MGI:3768605 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
JBrowse link
negative regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Mesp1 mesoderm posterior bHLH transcription factor 1 involved_in ISO (MGI:4441249|PMID:18593560) RGD PMID:18593560 MGI:4441249 NCBI chr 1:133,738,357...133,739,875
Ensembl chr 1:133,738,357...133,739,875
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 acts_upstream_of_or_within ISO MGI:98956 (MGI:3711603|PMID:17462603) RGD PMID:17462603 MGI:3711603 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
JBrowse link
paraxial mesodermal cell fate commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxc2 forkhead box C2 acts_upstream_of_or_within ISO MGI:1857865 (MGI:86990|PMID:9106663) RGD PMID:9106663 MGI:86990 NCBI chr19:49,186,034...49,188,736
Ensembl chr19:49,185,662...49,188,737
JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO MGI:1857489 (MGI:86727|PMID:9126297) RGD PMID:9126297 MGI:86727 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
positive regulation of mesodermal cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja1 gap junction protein, alpha 1 involved_in ISO (PMID:30599359) RGD PMID:30599359 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
positive regulation of mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A involved_in ISO (PMID:20559569) RGD PMID:20559569 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
regulation of lateral mesodermal cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO MGI:95522 (MGI:3702797|PMID:16943278) RGD PMID:16943278 MGI:3702797 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:1338938 (MGI:3702797|PMID:16943278) RGD PMID:16943278 MGI:3702797 NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cellular developmental process 4477
        cell differentiation 4382
          mesodermal cell differentiation 31
            axial mesodermal cell differentiation + 1
            hemangioblast cell differentiation 1
            intermediate mesodermal cell differentiation + 1
            lateral mesodermal cell differentiation + 3
            mesodermal cell fate commitment + 17
            negative regulation of mesodermal cell differentiation + 3
            paraxial mesodermal cell differentiation + 2
            positive regulation of mesodermal cell differentiation + 2
            regulation of mesodermal cell differentiation + 7
Path 2
Term Annotations click to browse term
  biological_process 19492
    developmental process 6769
      anatomical structure development 6195
        multicellular organism development 5632
          embryo development 1315
            embryonic morphogenesis 689
              gastrulation 206
                formation of primary germ layer 128
                  mesoderm formation 75
                    mesodermal cell differentiation 31
                      axial mesodermal cell differentiation + 1
                      hemangioblast cell differentiation 1
                      intermediate mesodermal cell differentiation + 1
                      lateral mesodermal cell differentiation + 3
                      mesodermal cell fate commitment + 17
                      negative regulation of mesodermal cell differentiation + 3
                      paraxial mesodermal cell differentiation + 2
                      positive regulation of mesodermal cell differentiation + 2
                      regulation of mesodermal cell differentiation + 7
paths to the root