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substance-induced psychosis - Ontology Report - Rat Genome Database

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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:substance-induced psychosis
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Accession:DOID:8646 term browser browse the term
Definition:Psychotic organic mental disorders resulting from the toxic effect of drugs and chemicals or other harmful substance.
Synonyms:exact_synonym: Drug Psychoses;   Toxic Psychoses;   substance-induced psychoses
 primary_id: MESH:D011605;   RDO:0006434
 xref: ICD9CM:293.89
For additional species annotation, visit the Alliance of Genome Resources.

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substance-induced psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism CTD PMID:17196621 NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853 		JBrowse link
G ADORA2A adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20799992 NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21041608 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G CAMK2B calcium/calmodulin dependent protein kinase II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17603807 NCBI chr 7:44,930,859...45,040,078
Ensembl chr 7:45,001,267...45,110,342 		JBrowse link
G ESR1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19386276 NCBI chr 6:149,507,599...149,918,523
Ensembl chr 6:154,317,002...154,631,551 		JBrowse link
G GRM2 glutamate metabotropic receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20211215 NCBI chr 3:51,639,792...51,652,779
Ensembl chr 3:52,873,144...52,884,395 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15729709 NCBI chr11:62,942,756...62,945,701
Ensembl chr11:66,253,421...66,256,472 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19747927 NCBI chr 5:50,045,266...50,049,636
Ensembl chr 5:51,692,416...51,693,684 		JBrowse link
G HTR6 5-hydroxytryptamine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20705401 NCBI chr 1:18,619,683...18,635,822
Ensembl chr 1:19,662,978...19,678,680 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19566775 NCBI chr 4:155,583,870...155,604,336
Ensembl chr 4:167,372,310...167,381,597 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16402083 NCBI chr 6:151,827,323...151,937,658
Ensembl chr 6:156,517,661...157,088,251 		JBrowse link
G PHB1 prohibitin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18504422 NCBI chr17:8,189,555...8,200,491
Ensembl chr17:8,175,968...8,186,790 		JBrowse link
G PICK1 protein interacting with PRKCA 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17606663 Ensembl chr22:36,796,015...36,814,469 JBrowse link
G RGS9 regulator of G protein signaling 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17318883 NCBI chr17:59,085,707...59,176,368
Ensembl chr17:64,262,585...64,389,559 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12931138 Ensembl chr 5:1,437,567...1,488,829 JBrowse link
G SNCA synuclein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:15542733 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600 		JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16807759 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960 		JBrowse link
alcohol-induced mental disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:26711020 NCBI chr12:109,343,020...109,385,060
Ensembl chr12:112,734,243...112,776,471 		JBrowse link
G ANKK1 ankyrin repeat and kinase domain containing 1 ISO DNA:SNP:exon:rs1800497(human) RGD PMID:18669994 RGD:401959336 NCBI chr11:108,267,717...108,280,635
Ensembl chr11:112,111,003...112,123,382 		JBrowse link
G DRD2 dopamine receptor D2 ISO DNA:SNP:cds:957C>T(human) RGD PMID:18669994 RGD:401959336 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G FOXO4 forkhead box O4 ISO protein:increased phosphorylation:small intestine: RGD PMID:23292333 RGD:10402360 NCBI chr  X:60,364,466...60,372,147
Ensembl chr  X:70,422,504...70,429,971 		JBrowse link
G GSR glutathione-disulfide reductase treatment ISO RGD PMID:24972622 RGD:10401897 NCBI chr 8:29,990,543...30,040,157
Ensembl chr 8:27,180,300...27,229,557 		JBrowse link
G HECTD4 HECT domain E3 ubiquitin protein ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35713687 NCBI chr12:109,756,303...109,978,510
Ensembl chr12:113,151,017...113,311,809 		JBrowse link
alcohol-related birth defects term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK3 ankyrin 3 ISO DNA:SNP:CDS:rs7917190 RGD PMID:29109170 RGD:597830079 NCBI chr10:56,560,589...57,269,952
Ensembl chr10:58,790,696...59,602,954 		JBrowse link
G ARHGEF10 Rho guanine nucleotide exchange factor 10 ISO associated with cleft lip; DNA:SNP: :rs2294035, rs4876274 RGD PMID:31372216 RGD:597830081 NCBI chr 8:5,381,357...5,541,094
Ensembl chr 8:1,724,413...1,862,917 		JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 ISO DNA:SNP:CDS:rs4659444 RGD PMID:29109170 RGD:597830079 NCBI chr 1:25,792,428...25,837,950
Ensembl chr 1:26,856,057...26,900,532 		JBrowse link
alcoholic psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTR2A 5-hydroxytryptamine receptor 2A ISO DNA:SNP:promoter:-1438G>A RGD PMID:11842624 RGD:401900738 NCBI chr13:27,976,415...28,042,941
Ensembl chr13:46,694,273...46,759,826 		JBrowse link
drug psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB2 arrestin beta 2 ISO protein:increased expression:striatum RGD PMID:26174132 RGD:11534754 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:26174132 RGD:11534754 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G GAD1 glutamate decarboxylase 1 susceptibility ISO protein:decreased expression:prefrontal cortex
associated with amphetamine abuse; DNA:haplotype: :rs769404���rs701492(human)		 RGD PMID:24200867 PMID:27967329 RGD:401900122 RGD:401900162 NCBI chr2B:58,100,623...58,145,045
Ensembl chr2B:175,558,538...175,602,944 		JBrowse link
G GAD2 glutamate decarboxylase 2 susceptibility ISO associated with amphetamine abuse; DNA:SNP: :rs2236418(human) RGD PMID:27967329 RGD:401900122 NCBI chr10:26,392,877...26,481,859
Ensembl chr10:26,759,243...26,843,197 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO associated with amphetamine abuse;DNA:SNP:intron:IVS2+691G>C (human) RGD PMID:16402083 RGD:401827939 NCBI chr 6:151,827,323...151,937,658
Ensembl chr 6:156,517,661...157,088,251 		JBrowse link
fetal alcohol spectrum disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK3 ankyrin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29109170 NCBI chr10:56,560,589...57,269,952
Ensembl chr10:58,790,696...59,602,954 		JBrowse link
G APOE apolipoprotein E ISO RGD PMID:15007105 RGD:12904641 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G AVP arginine vasopressin ISO mRNA:decreased expression:hypothalamic nucleus RGD PMID:15142835 RGD:596933086 NCBI chr20:3,169,094...3,172,900 JBrowse link
G BPIFA1 BPI fold containing family A member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15513904 NCBI chr20:29,524,619...29,532,996
Ensembl chr20:30,642,191...30,649,515 		JBrowse link
G C3 complement C3 ISO protein:increased activity:blood RGD PMID:30657461 RGD:408418720 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699 		JBrowse link
G C5 complement C5 ISO protein:increased activity:blood RGD PMID:30657461 RGD:408418720 NCBI chr 9:92,069,574...92,202,513
Ensembl chr 9:120,426,354...120,523,856 		JBrowse link
G CAT catalase ISO CTD Direct Evidence: therapeutic CTD PMID:26074427 NCBI chr11:34,413,253...34,446,831
Ensembl chr11:34,289,603...34,323,160 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 sexual_dimorphism ISO associated with chronic mild stress, age effect; mRNA:altered expression:hippocampus (rat) RGD PMID:29251811 RGD:401965484 NCBI chr17:11,261,435...11,313,630
Ensembl chr17:11,650,057...11,701,208 		JBrowse link
G DIO3 iodothyronine deiodinase 3 treatment ISO RGD PMID:23763370 RGD:13432044 NCBI chr14:82,188,126...82,190,220 JBrowse link
G DNMT1 DNA methyltransferase 1 ISO mRNA,protein:increased expression:Pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr19:9,681,847...9,745,334
Ensembl chr19:10,342,478...10,406,972 		JBrowse link
G DNMT3B DNA methyltransferase 3 beta ISO mRNA:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr20:29,049,993...29,096,957
Ensembl chr20:30,186,069...30,215,487 		JBrowse link
G DRD2 dopamine receptor D2 ISO mRNA:decreased expression: pituitary gland (rat)
DNA:Hypermethylation:promoter		 RGD PMID:26509893 PMID:28710248 RGD:11344152 RGD:401960105 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G EHMT2 euchromatic histone lysine methyltransferase 2 ISO mRNA:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr 6:31,542,946...31,560,894
Ensembl chr 6:32,429,271...32,451,844 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 sexual_dimorphism
treatment		 ISO in male mice only; mRNA:increased expression:frontal cortex: RGD PMID:23763370 PMID:30312858 RGD:13432044 RGD:405866345 NCBI chr15:3,129,481...3,357,495
Ensembl chr15:23,981,359...24,058,357 		JBrowse link
G GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2 ISO mRNA:increased expression:posterior hypothalamic region (rat) RGD PMID:18514412 RGD:402528884 NCBI chr 5:157,436,113...157,529,586
Ensembl chr 5:164,068,122...164,222,179 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B treatment ISO RGD PMID:22037411 PMID:23763370 RGD:13210751 RGD:13432044 NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799 		JBrowse link
G HDAC2 histone deacetylase 2 ISO mRNA,protein:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr 6:111,731,139...111,761,826
Ensembl chr 6:115,802,367...115,833,004 		JBrowse link
G HDAC4 histone deacetylase 4 ISO mRNA,protein:increased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr2B:126,287,745...126,649,815
Ensembl chr2B:245,123,061...245,427,054 		JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 ISO protein:increased expression:placenta (rat) RGD PMID:26342748 RGD:401965481 NCBI chr16:47,776,118...47,782,861
Ensembl chr16:67,165,215...67,171,417 		JBrowse link
G IGF1 insulin like growth factor 1 ISO mRNA:decreased expression:cerebellum (rat) RGD PMID:16909201 RGD:12904886 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO protein:decreased activity:cerebellum (rat) RGD PMID:16909201 RGD:12904886 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974 		JBrowse link
G MAT2A methionine adenosyltransferase 2A ISO mRNA:decreased expression:brain (rat) RGD PMID:26180184 RGD:11074449 NCBI chr2A:85,589,301...85,595,437
Ensembl chr2A:87,141,857...87,148,322 		JBrowse link
G MECP2 methyl-CpG binding protein 2 treatment ISO mRNA:increased expression:pituitary gland (rat) RGD PMID:23763370 PMID:26509893 RGD:11344152 RGD:13432044 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase ISO mRNA:decreased expression:brain (rat) RGD PMID:26180184 RGD:11074449 NCBI chr 1:212,353,195...212,463,304
Ensembl chr 1:217,358,050...217,460,946 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25511929 NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 sexual_dimorphism ISO associated with chronic mild stress, age effect; mRNA:altered expression:hippocampus (rat) RGD PMID:29251811 RGD:401965484 NCBI chr 4:140,418,624...140,785,180
Ensembl chr 4:152,108,508...152,430,298 		JBrowse link
G OPRK1 opioid receptor kappa 1 ISO DNA, mRNA:hypomethylation, increased expression:ventral tegmental area, prefrontal cortex RGD PMID:29678771 RGD:401851055 NCBI chr 8:49,650,844...49,677,494
Ensembl chr 8:47,029,313...47,056,577 		JBrowse link
G OPRL1 opioid related nociceptin receptor 1 ISO mRNA:decreased expression:ventral tegmental area RGD PMID:29678771 RGD:401851055 Ensembl chr20:62,004,176...62,017,866 JBrowse link
G PDYN prodynorphin ISO DNA, mRNA:hypomethylation, altered expression:ventral tegmental area, nucleus accumbens RGD PMID:29678771 RGD:401851055 NCBI chr20:2,092,171...2,108,141
Ensembl chr20:1,856,850...1,872,452 		JBrowse link
G PER2 period circadian regulator 2 treatment ISO RGD PMID:31329297 RGD:405878078 NCBI chr2B:125,477,021...125,521,577
Ensembl chr2B:244,328,122...244,371,040 		JBrowse link
G PNOC prepronociceptin ISO mRNA:increased expression:nucleus accumbens RGD PMID:29678771 RGD:401851055 NCBI chr 8:27,596,413...27,622,844
Ensembl chr 8:24,796,638...24,822,758 		JBrowse link
G POMC proopiomelanocortin treatment ISO RGD PMID:31329297 RGD:405878078 NCBI chr2A:25,161,668...25,165,600
Ensembl chr2A:25,258,768...25,262,706 		JBrowse link
G PRL prolactin ISO mRNA,protein:increased expression:pituitary gland, blood plasma (rat)
mRNA, protein:increased expression:pituitary gland, blood plasma (rat)		 RGD PMID:26509893 PMID:28710248 RGD:11344152 RGD:401960105 NCBI chr 6:22,109,974...22,125,433
Ensembl chr 6:22,450,132...22,459,829 		JBrowse link
G PTEN phosphatase and tensin homolog ISO Protein:increased expression, increased activity:cerebellum (rat) RGD PMID:12700235 RGD:12801493 NCBI chr10:84,587,841...84,689,043
Ensembl chr10:88,093,539...88,194,605 		JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 treatment ISO RGD PMID:23763370 RGD:13432044 NCBI chr15:57,933,152...58,063,824
Ensembl chr15:76,891,556...77,022,534 		JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29109170 NCBI chr 1:25,792,428...25,837,950
Ensembl chr 1:26,856,057...26,900,532 		JBrowse link
G SETD7 SET domain containing 7, histone lysine methyltransferase ISO mRNA:decreased expression:pituitary gland (rat) RGD PMID:26509893 RGD:11344152 NCBI chr 4:131,869,999...131,921,342
Ensembl chr 4:143,167,190...143,227,732 		JBrowse link
G SLC25A12 solute carrier family 25 member 12 treatment ISO RGD PMID:23763370 RGD:13432044 NCBI chr2B:59,071,123...59,297,327
Ensembl chr2B:176,532,940...176,641,894 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO mRNA:decreased expression:brain (rat) RGD PMID:26180184 RGD:11074449 NCBI chr17:26,546,177...26,572,301
Ensembl chr17:27,050,900...27,092,882 		JBrowse link
G TLR4 toll like receptor 4 ameliorates ISO RGD PMID:30312858 RGD:405866345 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G UBE3A ubiquitin protein ligase E3A treatment ISO RGD PMID:23763370 RGD:13432044 NCBI chr15:4,494,029...4,595,415
Ensembl chr15:22,747,075...22,825,459 		JBrowse link
fetal alcohol syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RHOA ras homolog family member A ISO protein:increased activation:neuron, cerebellum RGD PMID:17109064 RGD:2298867 NCBI chr 3:49,282,009...49,339,887 JBrowse link
Postoperative Cognitive Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor ISO mRNA, protein:increased expression:hippocampus RGD PMID:23078219 RGD:597805826 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:24814703 RGD:10047100 NCBI chr 3:145,722,475...145,767,550
Ensembl chr 3:153,341,947...153,345,380 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 treatment ISO RGD PMID:30221701 RGD:597931096 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G APP amyloid beta precursor protein treatment ISO protein:increased expression:plasma
protein:increased expression:hippocampus		 RGD PMID:30221701 PMID:33574912 PMID:35317728 RGD:597830151 RGD:597830178 RGD:597931096 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G BACE1 beta-secretase 1 treatment ISO RGD PMID:30221701 PMID:33574912 RGD:597830178 RGD:597931096 NCBI chr11:112,120,950...112,151,505
Ensembl chr11:116,054,303...116,084,812 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:33574912 RGD:597830178 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468 		JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO RGD PMID:33574912 RGD:597830178 NCBI chr18:56,481,212...56,679,012
Ensembl chr18:59,802,443...59,992,100 		JBrowse link
G BDNF brain derived neurotrophic factor treatment ISO associated with brain ischemia RGD PMID:29065194 PMID:29571823 PMID:29599834 PMID:30232930 PMID:32564283 More... RGD:401959211 RGD:401965400 RGD:401976548 RGD:405850212 RGD:596933096 RGD:596936243 RGD:596936414 NCBI chr11:27,618,322...27,687,661
Ensembl chr11:27,520,312...27,589,239 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:30221701 PMID:33574912 RGD:597830178 RGD:597931096 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 treatment ISO protein:decreased phosphorylation:hippocampus RGD PMID:29571823 PMID:36688960 PMID:37736695 RGD:401959211 RGD:401959611 RGD:401960090 NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130 		JBrowse link
G GDNF glial cell derived neurotrophic factor treatment ISO protein:decreased expression:hippocampus,urine
protein:altered expression:hippocampus, urine
associated with rheumatic heart disease;protein:increased expression:serum		 RGD PMID:25251457 PMID:28918204 PMID:29512789 PMID:33324197 PMID:34728231 More... RGD:401959611 RGD:405849389 RGD:405850212 RGD:405850250 RGD:405850251 RGD:405866364 NCBI chr 5:72,539,374...72,566,918
Ensembl chr 5:77,577,313...77,601,362 		JBrowse link
G HMGB1 high mobility group box 1 ISO mRNA, protein:increased expression:hippocampus RGD PMID:23078219 RGD:597805826 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527 		JBrowse link
G IGF1 insulin like growth factor 1 treatment ISO mRNA:decreased expression:plasma
mRNA:decreased expression:hippocampus		 RGD PMID:33574912 PMID:35317728 RGD:597830151 RGD:597830178 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IGFBP7 insulin like growth factor binding protein 7 ISO protein:increased expression:plasma (human) RGD PMID:25543030 RGD:401960875 NCBI chr 4:66,808,845...66,888,301
Ensembl chr 4:73,382,745...73,462,087 		JBrowse link
G IL1B interleukin 1 beta treatment ISO mRNA, protein:increased expression:hippocampus
protein:increased expression:hippocampus (rat)		 RGD PMID:22959208 PMID:23078219 PMID:29571823 PMID:30221701 PMID:33390808 RGD:401959211 RGD:401965467 RGD:597805826 RGD:597931096 RGD:7204702 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G IL1RN interleukin 1 receptor antagonist treatment ISO human protein in a rat model RGD PMID:23077050 RGD:8551854 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839 		JBrowse link
G IL6 interleukin 6 treatment ISO protein:increased expression:hippocampus (rat) RGD PMID:28684969 PMID:30221701 PMID:33390808 RGD:401965467 RGD:597538492 RGD:597931096 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G IREB2 iron responsive element binding protein 2 ISO protein:increased expression:hippocampus (rat) RGD PMID:23229539 RGD:12904023 NCBI chr15:57,367,314...57,430,322
Ensembl chr15:76,331,610...76,394,476 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment ISO protein:decreased phosphorylation:hippocampus RGD PMID:36688960 PMID:37736695 RGD:401959611 RGD:401960090 NCBI chr22:3,883,119...3,990,368
Ensembl chr22:20,365,487...20,450,335 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment ISO protein:decreased phosphorylation:hippocampus RGD PMID:36688960 PMID:37736695 RGD:401959611 RGD:401960090 Ensembl chr16:30,489,362...30,498,017 JBrowse link
G NGF nerve growth factor treatment ISO associated with brain ischemia RGD PMID:29599834 PMID:30481505 PMID:34964700 RGD:401965395 RGD:401965400 RGD:401976548 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 treatment ISO associated with Traumatic Brain Injuries;mRNA:decreased expression:hippocampus, hypothalamus RGD PMID:28086911 PMID:36637480 RGD:408345237 RGD:408364984 NCBI chr 5:138,634,278...139,089,171
Ensembl chr 5:144,741,452...144,865,269 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 ISO protein:increased expression:hippocampus (rat) RGD PMID:33390808 RGD:401965467 NCBI chr 4:140,418,624...140,785,180
Ensembl chr 4:152,108,508...152,430,298 		JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 treatment ISO RGD PMID:29065194 PMID:30232930 PMID:32564283 RGD:596933096 RGD:596936243 RGD:596936414 NCBI chr 9:39,663,986...40,208,770
Ensembl chr 9:84,021,837...84,372,678 		JBrowse link
G PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta treatment ISO RGD PMID:30221701 RGD:597931096 NCBI chr 3:135,685,120...135,867,096
Ensembl chr 3:143,288,563...143,431,314 		JBrowse link
G TLR2 toll like receptor 2 treatment ISO RGD PMID:28684969 PMID:32300366 RGD:597538486 RGD:597538492 NCBI chr 4:146,024,653...146,091,388
Ensembl chr 4:157,866,977...157,869,331 		JBrowse link
G TLR4 toll like receptor 4 treatment ISO RGD PMID:28684969 PMID:32300366 RGD:597538486 RGD:597538492 NCBI chr 9:88,827,495...88,840,458
Ensembl chr 9:117,180,550...117,190,711 		JBrowse link
G TNF tumor necrosis factor treatment ISO mRNA, protein:increased expression:hippocampus
protein:increased expression:hippocampus (rat)		 RGD PMID:23078219 PMID:29571823 PMID:33390808 RGD:401959211 RGD:401965467 RGD:597805826 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
subacute delirium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Yt blood group) disease_progression ISO RGD PMID:8043620 RGD:405855847 NCBI chr 7:92,915,065...92,922,079
Ensembl chr 7:106,311,944...106,318,184 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO mRNA, protein:increased expression:hippocampal formation, amygdala RGD PMID:27760517 RGD:405850209 NCBI chr 5:50,045,266...50,049,636
Ensembl chr 5:51,692,416...51,693,684 		JBrowse link
G TPH2 tryptophan hydroxylase 2 ISO mRNA:increased expression:hippocampus, prefrontal cortex RGD PMID:36750928 RGD:597805905 NCBI chr12:69,460,883...69,557,329
Ensembl chr12:72,318,908...72,412,557 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15835
    Chemically-Induced Disorders 1254
      substance-related disorder 674
        substance-induced psychosis 95
          alcohol-induced mental disorder + 49
          drug-induced mental disorder + 5
          subacute delirium + 31
Path 2
Term Annotations click to browse term
  disease 15835
    disease of anatomical entity 15491
      nervous system disease 13589
        central nervous system disease 12155
          brain disease 11419
            disease of mental health 8264
              cognitive disorder 2167
                psychotic disorder 1189
                  substance-induced psychosis 95
                    alcohol-induced mental disorder + 49
                    drug-induced mental disorder + 5
                    subacute delirium + 31
paths to the root