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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:substance-related disorder
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Accession:DOID:303 term browser browse the term
Definition:A disease of mental health involving the abuse or dependence on a substance that is ingested in order to produce a high, alter one's senses, or otherwise affect functioning. (DO)
Synonyms:exact_synonym: PSAB;   organic mental disorders, substance induced;   polysubstance abuse, susceptibility to;   substance addiction;   substance use disorder;   substance use disorders;   substance-related disorders
 broad_synonym: psychiatric toxicity
 related_synonym: Dopamine receptor d2, reduced brain density of
 primary_id: MESH:D019966
 alt_id: OMIM:606581
 xref: EFO:0011059;   MONDO:0002494;   NCI:C92203
For additional species annotation, visit the Alliance of Genome Resources.



show annotations for term's descendants           Sort by:
substance-related disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Ablim1 actin-binding LIM protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:256,083,747...256,372,075
Ensembl chr 1:256,084,297...256,371,969
JBrowse link
G Adarb2 adenosine deaminase RNA specific B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831
JBrowse link
G Aff3 ALF transcription elongation factor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 9:40,399,099...40,856,716
Ensembl chr 9:40,404,375...40,857,247
JBrowse link
G Agbl4 AGBL carboxypeptidase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:125,254,963...126,534,367
Ensembl chr 5:125,254,956...126,534,367
JBrowse link
G Akap7 A-kinase anchoring protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:20,087,190...20,217,799
Ensembl chr 1:20,087,373...20,217,797
JBrowse link
G Ano4 anoctamin 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 7:23,329,015...23,738,423
Ensembl chr 7:23,329,070...23,738,434
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798
JBrowse link
G Bpifa2 BPI fold containing family A, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:142,493,379...142,501,343
Ensembl chr 3:142,493,379...142,501,337
JBrowse link
G C18h5orf63 similar to human chromosome 5 open reading frame 63 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr18:50,424,079...50,442,172
Ensembl chr18:50,424,079...50,441,973
JBrowse link
G C1h19orf18 similar to human chromosome 19 open reading frame 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:73,022,324...73,049,934
Ensembl chr 1:73,025,988...73,049,736
JBrowse link
G Cadps2 calcium dependent secretion activator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829
JBrowse link
G Ccdc91 coiled-coil domain containing 91 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:180,402,327...180,574,364
Ensembl chr 4:180,402,376...180,574,364
JBrowse link
G Cd274 CD274 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cdcp1 CUB domain containing protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 8:122,828,685...122,865,345
Ensembl chr 8:122,828,685...122,865,388
JBrowse link
G Cdh13 cadherin 13 ISO
IMP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20098672 PMID:28387990 RGD:13503340 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
JBrowse link
G Cdh13em1Mcwi cadherin 13; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP knock-out compared to wild-type rats RGD PMID:28387990 RGD:13503340
G Cers6 ceramide synthase 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:53,630,637...53,879,692
Ensembl chr 3:53,630,959...53,876,848
JBrowse link
G Cftr CF transmembrane conductance regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Chchd3 coiled-coil-helix-coiled-coil-helix domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:61,360,352...61,616,850
Ensembl chr 4:61,360,353...61,616,847
JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 2:185,138,526...185,217,498
Ensembl chr 2:185,139,308...185,217,595
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20393457 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:20438829 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9888857 PMID:18690112 PMID:21513772 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Colec12 collectin sub-family member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618
JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
JBrowse link
G Csmd3 CUB and Sushi multiple domains 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 7:78,747,322...80,066,466
Ensembl chr 7:78,748,480...80,066,369
JBrowse link
G Csrnp3 cysteine and serine rich nuclear protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:50,498,379...50,695,598
Ensembl chr 3:50,498,633...50,685,950
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Ctnna3 catenin alpha 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr20:23,614,469...25,200,026
Ensembl chr20:23,623,560...25,199,978
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17089107 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Ddx1 DEAD-box helicase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
JBrowse link
G Disc1 DISC1 scaffold protein severity ISO protein:altered expression:orbitofrontal cortex RGD PMID:15657124 RGD:5509834 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778
JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr20:8,692,939...8,946,780
Ensembl chr20:8,692,963...8,946,772
JBrowse link
G Dock1 dedicator of cyto-kinesis 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:189,467,143...189,983,777
Ensembl chr 1:189,467,143...189,983,768
JBrowse link
G Drd2 dopamine receptor D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16901644 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Dscam DS cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr11:35,921,924...36,507,100
Ensembl chr11:35,926,896...36,507,415
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Eipr1 EARP complex and GARP complex interacting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:45,388,451...45,502,089
Ensembl chr 6:45,388,376...45,502,083
JBrowse link
G Etv6 ETS variant transcription factor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992
JBrowse link
G Faah fatty acid amide hydrolase susceptibility ISO ClinVar Annotator: match by term: Polysubstance abuse, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:missense mutation:cds:p.P129T (human)
ClinVar
OMIM
CTD
RGD
PMID:12060782 PMID:15254019 PMID:16972078 PMID:19103437 PMID:23556448 More... RGD:1625741, RGD:1300311 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
JBrowse link
G Fam184a family with sequence similarity 184, member A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr20:32,934,424...33,056,626
Ensembl chr20:32,934,636...33,056,652
JBrowse link
G Fam184b family with sequence similarity 184, member B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr14:65,475,489...65,591,388
Ensembl chr14:65,475,489...65,591,388
JBrowse link
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299
JBrowse link
G Faslg Fas ligand IDA RGD PMID:15644446 RGD:1358616 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Fhod3 formin homology 2 domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr18:15,993,079...16,425,796
Ensembl chr18:15,993,324...16,425,796
JBrowse link
G Fkbp15 FKBP prolyl isomerase family member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:75,750,786...75,815,038
Ensembl chr 5:75,750,787...75,814,990
JBrowse link
G Frmd4a FERM domain containing 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr17:73,667,787...74,258,487
Ensembl chr17:73,667,789...74,258,687
JBrowse link
G Gba3 glucosylceramidase beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr14:60,574,974...60,721,411
Ensembl chr14:60,574,976...60,721,653
JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Grm5 glutamate metabotropic receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
JBrowse link
G Grm7 glutamate metabotropic receptor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IMP RGD PMID:30188517 RGD:13792724 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Hspa12a heat shock protein family A (Hsp70) member 12A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:257,935,642...258,096,602
Ensembl chr 1:257,935,644...258,096,846
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:16474401 RGD:2292548 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Hycc1 hyccin PI4KA lipid kinase complex subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:11,132,224...11,239,120
Ensembl chr 4:11,132,385...11,239,113
JBrowse link
G Insr insulin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
JBrowse link
G Klf12 KLF transcription factor 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056
JBrowse link
G Ldlrad3 low density lipoprotein receptor class A domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:88,239,529...88,481,340
Ensembl chr 3:88,239,622...88,481,267
JBrowse link
G Limch1 LIM and calponin homology domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr14:41,112,579...41,425,001
Ensembl chr14:41,114,803...41,425,191
JBrowse link
G Lrmda leucine rich melanocyte differentiation associated ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:1,223,098...2,284,764
Ensembl chr15:1,225,710...2,284,749
JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:127,720,066...129,737,511
Ensembl chr 3:127,720,181...129,734,492
JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639
JBrowse link
G Mpc1 mitochondrial pyruvate carrier 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:52,437,745...52,449,399
Ensembl chr 1:52,437,741...52,449,400
JBrowse link
G Mpp7 MAGUK p55 scaffold protein 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr17:55,439,939...55,706,810
Ensembl chr17:55,442,696...55,706,748
JBrowse link
G Msra methionine sulfoxide reductase A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:38,363,459...38,677,406
Ensembl chr15:38,351,445...38,676,585
JBrowse link
G Myo5c myosin VC ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 8:75,989,497...76,066,485
Ensembl chr 8:75,989,528...76,066,483
JBrowse link
G Myo6 myosin VI ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 8:81,087,157...81,242,022
Ensembl chr 8:81,087,139...81,239,292
JBrowse link
G Nme7 NME/NM23 family member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr13:76,657,303...76,786,768
Ensembl chr13:76,657,367...76,786,765
JBrowse link
G Npy neuropeptide Y ISO CTD Direct Evidence: marker/mechanism CTD PMID:19063928 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nrcam neuronal cell adhesion molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16123759 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992
JBrowse link
G Nrxn3 neurexin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:107,641,760...109,272,849
Ensembl chr 6:107,641,780...109,272,044
JBrowse link
G Oprd1 opioid receptor, delta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17622222 PMID:20098672 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
JBrowse link
G Oprm1 opioid receptor, mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27192616 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Or51e1 olfactory receptor family 51 subfamily E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:157,142,232...157,151,114
Ensembl chr 1:157,142,352...157,149,671
JBrowse link
G Pacs1 phosphofurin acidic cluster sorting protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:202,437,503...202,569,473
Ensembl chr 1:202,437,505...202,569,473
JBrowse link
G Parva parvin, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:166,547,142...166,704,958
Ensembl chr 1:166,547,132...166,704,950
JBrowse link
G Patj PATJ, crumbs cell polarity complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:113,061,985...113,364,807
Ensembl chr 5:113,062,118...113,364,807
JBrowse link
G Pbx1 PBX homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
JBrowse link
G Pcdh15 protocadherin related 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719
JBrowse link
G Pde1c phosphodiesterase 1C ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 4:85,300,858...85,777,948
Ensembl chr 4:85,300,858...85,863,219
JBrowse link
G Piwil1 piwi-like RNA-mediated gene silencing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr12:27,949,743...27,970,645
Ensembl chr12:27,949,744...27,970,580
JBrowse link
G Pla2r1 phospholipase A2 receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429
JBrowse link
G Polr1d RNA polymerase I and III subunit D ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr12:7,970,592...8,004,157
Ensembl chr12:7,970,595...8,005,624
JBrowse link
G Prkce protein kinase C, epsilon ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkch protein kinase C, eta ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654
JBrowse link
G Prpf4 pre-mRNA splicing tri-snRNP complex factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:75,859,934...75,873,924
Ensembl chr 5:75,859,924...75,873,919
JBrowse link
G Pten phosphatase and tensin homolog IMP RGD PMID:16474401 RGD:2292548 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Qsox1 quiescin sulfhydryl oxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459
JBrowse link
G Rad51b RAD51 paralog B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979
JBrowse link
G Rhbdd3 rhomboid domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr14:79,994,111...80,000,294
Ensembl chr14:79,994,158...80,000,175
JBrowse link
G Rtl6 retrotransposon Gag like 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 7:115,684,812...115,689,897
Ensembl chr 7:115,684,739...115,690,052
JBrowse link
G Samd4a sterile alpha motif domain containing 4A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:20,135,994...20,352,131
Ensembl chr15:20,134,377...20,348,380
JBrowse link
G Sema6d semaphorin 6D ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:111,883,415...111,941,100
Ensembl chr 3:111,883,872...111,941,094
JBrowse link
G Slc10a2 solute carrier family 10 member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475
JBrowse link
G Slc18a2 solute carrier family 18 member A2 IEP protein:increased cysteine nitrosylation:striatum, vesicle (rat) RGD PMID:17683483 RGD:5131179 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc22a3 solute carrier family 22 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17010131 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612
JBrowse link
G Slc2a13 solute carrier family 2 member 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 7:122,399,329...122,726,605
Ensembl chr 7:122,399,330...122,726,605
JBrowse link
G Slc45a2 solute carrier family 45, member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 2:59,963,599...59,996,408
Ensembl chr 2:59,963,706...59,996,317
JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19272758 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Slk STE20-like kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530
JBrowse link
G Spmip5 sperm microtubule inner protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:257,926,555...257,934,873
Ensembl chr 1:257,926,388...257,934,399
JBrowse link
G Syne1 spectrin repeat containing nuclear envelope protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:41,512,146...41,983,382
Ensembl chr 1:41,512,030...41,983,322
JBrowse link
G Tenm2 teneurin transmembrane protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr10:20,480,662...21,706,415
Ensembl chr10:20,481,854...21,705,597
JBrowse link
G Thsd4 thrombospondin type 1 domain containing 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 8:60,384,636...60,984,419
Ensembl chr 8:60,386,875...61,024,995
JBrowse link
G Tiam2 TIAM Rac1 associated GEF 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:43,918,179...44,119,499
Ensembl chr 1:43,918,174...44,119,493
JBrowse link
G Tmprss7 transmembrane serine protease 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr11:55,127,992...55,166,597
Ensembl chr11:55,128,998...55,164,882
JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:50,861,367...50,935,880
Ensembl chr 3:50,861,367...50,935,903
JBrowse link
G Wdr11 WD repeat domain 11 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:184,165,260...184,210,834
Ensembl chr 1:184,165,571...184,210,846
JBrowse link
G Xkr4 XK related 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 5:15,896,818...16,297,733
Ensembl chr 5:15,895,863...16,282,962
JBrowse link
G Xpo6 exportin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:180,672,114...180,761,543
Ensembl chr 1:180,672,119...180,761,543
JBrowse link
G Xylt1 xylosyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:171,643,925...171,929,774
Ensembl chr 1:171,643,925...171,926,783
JBrowse link
G Zfp366 zinc finger protein 366 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 2:30,578,552...30,640,546
Ensembl chr 2:30,578,715...30,642,182
JBrowse link
G Zfp385d zinc finger protein 385D ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr15:5,040,182...5,849,975
Ensembl chr15:5,042,572...5,423,367
JBrowse link
G Zfp606 zinc finger protein 606 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 1:72,981,920...73,022,423
Ensembl chr 1:72,981,989...73,008,072
JBrowse link
G Zfp804a zinc finger protein 804A ISO CTD Direct Evidence: marker/mechanism CTD PMID:20098672 NCBI chr 3:67,033,481...67,267,769
Ensembl chr 3:67,034,170...67,263,607
JBrowse link
Acute Alcohol Sensitivity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Alcohol sensitivity, acute | ClinVar Annotator: match by term: Susceptibility to hangover
CTD
ClinVar
PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 More... NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
alcohol dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide ISO ClinVar Annotator: match by term: Alcohol dependence ClinVar
OMIM
PMID:3397059 PMID:3758060 PMID:10090900 PMID:15863807 PMID:17718394 More... NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide ISO RGD PMID:20077761 RGD:401827938 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Ago1 argonaute RISC component 1 susceptibility ISO DNA:SNP:intron:A>G(rs595961)(human) RGD PMID:25495208 RGD:401900681 NCBI chr 5:138,722,111...138,757,118
Ensembl chr 5:138,722,111...138,773,546
JBrowse link
G Ago2 argonaute RISC catalytic component 2 susceptibility ISO DNA:SNP:promoter:A>C(rs4961280)(human) RGD PMID:25495208 RGD:401900681 NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO ClinVar Annotator: match by term: Alcohol dependence
DNA:SNP: :1510G>A (human)
ClinVar
RGD
PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 More... RGD:401827938, RGD:401827936 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 susceptibility ISO DNA:polymorphism:exon:
DNA:SNP,haplotype:exon:rs1800497(human)
RGD PMID:28574012 PMID:23443985 RGD:401959222, RGD:401959307 NCBI chr 8:49,779,862...49,788,024
Ensembl chr 8:49,779,862...49,788,024
JBrowse link
G Arrb2 arrestin, beta 2 IEP mRNA:decreased expression:nucleus accumbens RGD PMID:34919270 RGD:401938593 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Avpr1b arginine vasopressin receptor 1B IEP RGD PMID:21309953 RGD:14700679 NCBI chr13:43,046,531...43,059,046
Ensembl chr13:43,046,267...43,057,792
JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IDA
IEP
RGD PMID:34453945 PMID:32579730 RGD:401959604, RGD:401959610 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C IEP mRNA, protein:increased expression:amygdala, hippocampus (rat)
protein:increased expression:inferior colliculus (human)
RGD PMID:27905406 PMID:25556199 RGD:152985537, RGD:152985539 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cdk20 cyclin-dependent kinase 20 susceptibility ISO DNA:SNP:: (rs560019) (human) RGD PMID:18438686 RGD:401851917 NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826
JBrowse link
G Chat choline O-acetyltransferase ISO protein:decreased expression:hippocampus,septum,striatum RGD PMID:8436061 RGD:401976285 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Comt catechol-O-methyltransferase susceptibility
sexual_dimorphism
onset
disease_progression
ISO associated with Alzheimer's disease; DNA:SNP:cd: P.V158M G>A (rs4680) (human)
DNA:SNPs,haplotypes:: (rs165774,rs4680) (human)
DNA:SNPs,haplotype:exon 4: p.V158M (rs4680) (human)
DNA:SNP:cd: p.V158M (rs4680) (human)
DNA:SNP:cd: p.V158M (human)
associated with major depressive disorder; DNA:SNP:cd: p.V158M (human)
DNA:polymorphism:exon 4: p.V158M (rs4680)(human)
associated with schizophrenia; DNA:promoter:Hypermethylation
associated with Trauma and Stressor Related Disorders ; DNA:polymorphism:exon: p.V158M (human)
RGD PMID:25491588 PMID:22208661 PMID:16499480 PMID:24390676 PMID:16648777 More... RGD:11073926, RGD:401959747, RGD:401959300, RGD:401940156, RGD:401940155, RGD:401940149, RGD:401940148, RGD:401940146, RGD:401940133, RGD:401940131, RGD:401940120, RGD:401940118 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment ISO
IDA
IEP
DNA:SNP:exon:rs35349697
mRNA,protein:decreased expression:hippocampus
RGD PMID:24704376 PMID:21951632 PMID:32579730 PMID:34453945 PMID:37031608 RGD:401938627, RGD:401959743, RGD:401959610, RGD:401959604, RGD:401959603 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO protein:increased expression:brain RGD PMID:12354285 RGD:401901262 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Dgcr8 DGCR8 microprocessor complex subunit susceptibility ISO DNA:SNP:3���-UTR:G>T(rs1640299)(human) RGD PMID:25495208 RGD:401900681 NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242
JBrowse link
G Drd2 dopamine receptor D2 onset
susceptibility
ISO DNA:insertion, deletion:promoter:
DNA:SNP: :rs1800498(human)
RGD PMID:23238469 PMID:36825486 RGD:401959213, RGD:401959301 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd4 dopamine receptor D4 no_association ISO DNA:repeats:exon: RGD PMID:9342196 RGD:401959738 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit treatment IEP RGD PMID:20626732 RGD:401851075 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 susceptibility
treatment
ISO
IMP
HEP
DNA:SNP, haplotype:intron: C>G (rs29220) (human)
DNA:SNP:Exon 11: T1974C (Human)
mRNA:decreased expression:hippocampus (rat)
DNA:SNP:intron: (rs29220) (human)
DNA:SNP:intron: (rs29253) (human)
RGD PMID:26727527 PMID:36095322 PMID:36095322 PMID:10412185 PMID:22253714 More... RGD:11552767, RGD:401976442, RGD:401976442, RGD:401959601, RGD:401900163, RGD:401940102, RGD:401940100 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 HEP mRNA:decreased expression:hippocampus (rat) RGD PMID:22253714 RGD:401900163 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 susceptibility ISO ClinVar Annotator: match by term: Alcohol dependence ClinVar
OMIM
PMID:25741868 NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944
JBrowse link
G Gad1 glutamate decarboxylase 1 susceptibility
onset
ISO DNA:SNPs, haplotype:5'UTR,IVS:Rs3749034,Rs2270335,Rs10439259(human)
DNA:SNPs: haplotype:multiple:rs1978340(human)
RGD PMID:17067345 PMID:19111404 RGD:401900127, RGD:401900129 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gad2 glutamate decarboxylase 2 susceptibility ISO DNA:SNP::-243A>G (rs2236418) RGD PMID:17034009 RGD:401900120 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
JBrowse link
G Gemin4 gem (nuclear organelle) associated protein 4 susceptibility ISO DNA:SNP:Promoter:C>T(rs910924)(human) RGD PMID:25495208 RGD:401900681 NCBI chr10:61,062,420...61,073,529
Ensembl chr10:61,066,425...61,073,431
Ensembl chr10:61,066,425...61,073,431
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 IEP protein:increased activity:plasma,liver,intestine: RGD PMID:6113606 RGD:14701046 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A susceptibility
ameliorates
ISO DNA:repeats:promoter:(GT)n
DNA:mutation:cds:A825W(mouse)
RGD PMID:21507155 PMID:33052417 PMID:29953905 RGD:401938633, RGD:401938638, RGD:401938635 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO RGD PMID:29582627 RGD:14700988 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO mRNA:increased expression:Brodmann (1909) area 9
DNA:SNP: :140G>C
RGD PMID:22176604 PMID:19060480 RGD:401900608, RGD:401900293 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A disease_progression
treatment
susceptibility
no_association
ISO
IMP
IEP
DNA:SNP: :102T>C (rs6313)
protein:decreased expression:agranular insular cortex, cingulate cortex, frontal cortex
DNA:SNP:promoter:-1438G>A (rs6311)
OMIM
RGD
PMID:23321485 PMID:8822536 PMID:15080502 PMID:19328219 PMID:19060480 More... RGD:401900291, RGD:401900739, RGD:401900737, RGD:401900304, RGD:401900293, RGD:401900297 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Lep leptin IDA
IEP
DNA:hypermethylation:promoter
protein:decreased expression:serum
RGD PMID:29912265 PMID:29912265 RGD:21201248, RGD:21201248 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment IDA RGD PMID:34453945 RGD:401959604 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment IDA RGD PMID:34453945 RGD:401959604 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Ngf nerve growth factor ISO protein:increased expression:serum
protein:decreased expression:plasma
RGD PMID:17434673 PMID:16737466 RGD:401965399, RGD:401965409 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 IEP mRNA:altered expression:central amygdaloid nucleus (rat) RGD PMID:28461696 RGD:401960064 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
JBrowse link
G Nucb2 nucleobindin 2 IEP mRNA,protein:decreased expression:hippocampus RGD PMID:37031608 RGD:401959603 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
JBrowse link
G Oprk1 opioid receptor, kappa 1 no_association ISO DNA:SNPs:intron:multiple
mRNA:increased expression:orbitofrontal cortex
DNA:SNP: :rs6473797 (human)
RGD PMID:16924269 PMID:21955155 PMID:24035285 RGD:401850571, RGD:401850584, RGD:401850579 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G Oprm1 opioid receptor, mu 1 no_association
treatment
sexual_dimorphism
ISO DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human)
DNA:SNP: :rs1799971 (human)
RGD PMID:16679777 PMID:24035285 PMID:30748046 PMID:11424981 PMID:35992511 More... RGD:401827936, RGD:401850579, RGD:401831038, RGD:401827953, RGD:401827952, RGD:401827944, RGD:11097488, RGD:401827938, RGD:401827938 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Pde4b phosphodiesterase 4B susceptibility ISO DNA:SNP:: (rs1937443) (human) RGD PMID:18438686 RGD:401851917 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdyn prodynorphin no_association
disease_progression
ISO DNA:SNP, hypermethylation:promoter:rs2235751 (human)
mRNA, protein:increased expression:dorsolateral prefrontal cortex, orbitofrontal cortex
DNA:SNP: :rs1997794 (human)
DNA:SNP, hypermethylation:dorsolateral prefrontal cortex:rs2281285 (human)
DNA:SNP: :rs2281285 (human)
DNA:SNPs: :multiple
DNA:SNPs, haplotypes:multiple
RGD PMID:28336495 PMID:21955155 PMID:24035285 PMID:21521424 PMID:26502829 More... RGD:401850551, RGD:401850584, RGD:401850579, RGD:401850575, RGD:11535796, RGD:401850571, RGD:401850565, RGD:401850560 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Pomc proopiomelanocortin no_association ISO DNA:SNP: :rs934778 (human) RGD PMID:24035285 RGD:401850579 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Prl prolactin treatment ISO RGD PMID:11418230 RGD:401959332 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Slc29a1 solute carrier family 29 member 1 ISS OMIM:103780 MouseDO NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
JBrowse link
G Slc6a1 solute carrier family 6 member 1 susceptibility ISO DNA:insertion:promoter:: (human) RGD PMID:26727527 RGD:11552767 NCBI chr 4:147,448,961...147,482,295
Ensembl chr 4:147,466,965...147,482,293
JBrowse link
G Slc6a4 solute carrier family 6 member 4 disease_progression ISO DNA:VNTR RGD PMID:18552399 RGD:401900298 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Tas2r118 taste receptor, type 2, member 118 ISO OMIM NCBI chr 4:52,449,208...52,450,107
Ensembl chr 4:52,449,208...52,450,107
JBrowse link
G Tbx19 T-box transcription factor 19 susceptibility ISO DNA:SNP:: (rs1003502) (human) RGD PMID:18438686 RGD:401851917 NCBI chr13:77,450,848...77,484,475
Ensembl chr13:77,450,849...77,504,163
JBrowse link
Alcohol Myopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 IEP RGD PMID:14506614 RGD:1581765 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
alcohol use disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1c alcohol dehydrogenase 1C (class I), gamma polypeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:16404797 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide IMP RGD PMID:8462548 RGD:5129091 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:16404797 PMID:17590986 PMID:10780266 RGD:734551 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 severity ISO DNA:polymorphism: :rs1800497(human)
DNA:SNP,haplotype: :rs11604671, rs4938015 (human)
RGD PMID:32889058 PMID:21936764 RGD:401940151, RGD:401959296 NCBI chr 8:49,779,862...49,788,024
Ensembl chr 8:49,779,862...49,788,024
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein ISO associated with Prenatal Exposure Delayed Effects and anxiety disorder:DNA:Hypermthylation:promoter RGD PMID:30016666 RGD:401959614 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Bdnf brain-derived neurotrophic factor IEP
ISO
protein:decreased expression:plasma
protein:altered expression:brain
mRNA:decreased expression:hippocampus
mRNA,protein:decreased expression:hippocampus, plasma (rat)
protein:decreased expression:plasma (human)
RGD PMID:32135570 PMID:15307153 PMID:32497709 PMID:30277635 PMID:30277635 RGD:35673317, RGD:401965482, RGD:401950485, RGD:401938665, RGD:401938665 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Calb1 calbindin 1 IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:30277635 RGD:401938665 NCBI chr 5:29,375,624...29,402,532
Ensembl chr 5:29,375,642...29,402,431
JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 ISO mRNA:increased expression:prefrontal cortex RGD PMID:28714806 RGD:18337277 NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV IEP protein:decreased expression:brain, cingulate gyrus RGD PMID:11181917 RGD:401959326 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Cckar cholecystokinin A receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9922984 NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
JBrowse link
G Cdk20 cyclin-dependent kinase 20 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr17:701,122...707,869
Ensembl chr17:701,124...707,826
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18414406 NCBI chr 8:55,401,668...55,415,165
Ensembl chr 8:55,401,702...55,415,165
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:18414406 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146
JBrowse link
G Cnr1 cannabinoid receptor 1 sexual_dimorphism IEP associated with chronic stress in female rats RGD PMID:27894930 RGD:401959751 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Comt catechol-O-methyltransferase disease_progression ISO CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :rs4680(human)
DNA:polymorphism::
CTD
RGD
PMID:10395222 PMID:32889058 PMID:10395222 RGD:401940151, RGD:401940114 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Creb1 cAMP responsive element binding protein 1 sexual_dimorphism IEP
IDA
mRNA, protein:decreased expression:amygdala
protein:increased phosphorylation:liver
protein:altered expression, altered phosphorylation:liver, nucleus
RGD PMID:29991681 PMID:31262967 PMID:22269225 RGD:401938626, RGD:401959334, RGD:401959317 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crebbp CREB binding protein IEP mRNA, protein:decreased expression:amygdala RGD PMID:29991681 RGD:401938626 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
JBrowse link
G Crh corticotropin releasing hormone IEP mRNA:increased expression:central amygdaloid nucleus (rat) RGD PMID:20060104 RGD:5508173 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO RGD PMID:11988580 RGD:734822 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma, extracellular exosome
CTD
RGD
PMID:20843640 PMID:23819932 PMID:29404485 PMID:29404485 RGD:14700915, RGD:14700911, RGD:14700911 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Dbh dopamine beta-hydroxylase no_association ISO DNA:polymorphism:5' utr:g.-1021C>T (human)
DNA:polymorphism:cds:g.444G>A (human)
RGD PMID:16133787 PMID:16252068 RGD:1625572, RGD:1625571 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dcx doublecortin IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:30277635 RGD:401938665 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 ISO associated with Prenatal Exposure Delayed Effects and anxiety disorder:mRNA,protein:decreased expression:brain (mouse) RGD PMID:30016666 RGD:401959614 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Drd2 dopamine receptor D2 IEA GAD PMID:15118671 RGD:1331525 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd4 dopamine receptor D4 treatment
susceptibility
ISO DNA:repeats:exon:
associated with peer pressure;DNA:repeats:exon:
RGD PMID:25640830 PMID:26307243 RGD:11064848, RGD:401959598 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Ep300 E1A binding protein p300 IEP mRNA, protein:decreased expression:amygdala RGD PMID:29991681 RGD:401938626 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit IEP RGD PMID:23095216 RGD:10045658 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IEP mRNA:increased expression:cerebellum RGD PMID:34453331 RGD:401938639 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit treatment IEP
ISO
protein:increased expression:dorsal striatum (mouse)
protein:increased expression:brain (mouse)
RGD PMID:22792289 PMID:27380261 PMID:9835277 RGD:401851082, RGD:401901287, RGD:401901184 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Fshb follicle stimulating hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:8590623 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 susceptibility ISO DNA:SNP:intron: (rs2900512) (human) RGD PMID:28118741 RGD:401940105 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 susceptibility ISO DNA:SNPs:multiple:
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:22253714 PMID:15024690 RGD:6480257 NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gata4 GATA binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20585342 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO protein:increased expression:serum RGD PMID:25623403 RGD:401965480 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12747453 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Ghsr growth hormone secretagogue receptor ISO CTD Direct Evidence: therapeutic CTD PMID:23977009 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
JBrowse link
G Gphn gephyrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:14573320 RGD:1642372 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:14573320 PMID:16911840 RGD:1642372, RGD:1642200 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
JBrowse link
G Hdac2 histone deacetylase 2 IMP RGD PMID:23485013 RGD:9590265 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A treatment IMP RGD PMID:9631953 RGD:401900760 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A treatment ISO
IMP
IEP
CTD Direct Evidence: marker/mechanism
protein:increased expression:dorsal raphe, nucleus accumbens
mRNA, protein:decreased expression:cerebral cortex, liver
CTD
RGD
PMID:9631953 PMID:9347073 PMID:9347075 PMID:20501057 RGD:401900760, RGD:401900742, RGD:401900740, RGD:401900301 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C treatment IDA RGD PMID:24041931 RGD:401900761 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Htr3b 5-hydroxytryptamine receptor 3B susceptibility ISO DNA:SNP:cds:rs1176744(human) RGD PMID:20838391 RGD:6480660 NCBI chr 8:49,279,291...49,308,444
Ensembl chr 8:49,279,173...49,308,444
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 ISO DNA:SNP:intron: (rs7916403) (human) RGD PMID:21184583 RGD:150429835 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626
JBrowse link
G Igf2 insulin-like growth factor 2 ISO protein:decreased expression:plasma (human) RGD PMID:30277635 RGD:401938665 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Il10 interleukin 10 IEP mRNA:increased expression:liver RGD PMID:22269225 RGD:401959317 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 ISO DNA:SNP:promoter:rs2836016 (human) RGD PMID:21307845 RGD:6483053 NCBI chr11:34,061,702...34,308,758
Ensembl chr11:34,061,708...34,308,758
JBrowse link
G Lhb luteinizing hormone subunit beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:8590623 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Maoa monoamine oxidase A susceptibility ISO RGD PMID:15900229 RGD:1600720 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IEP protein:increased expression:liver RGD PMID:31262967 RGD:401959334 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO protein:increased expression, increased phosphorylation:liver RGD PMID:31262967 RGD:401959334 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IEP protein:increased expression:liver RGD PMID:31262967 RGD:401959334 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IDA RGD PMID:31262967 RGD:401959334 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 IEP RGD PMID:23095216 RGD:10045658 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Mir191 microRNA 191 onset IEP RGD PMID:32135570 RGD:35673317 NCBI chr 8:109,264,098...109,264,188 JBrowse link
G Mir195 microRNA 195 onset IEP RGD PMID:32135570 RGD:35673317 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924
JBrowse link
G Mir206 microRNA 206 onset IEP RGD PMID:32135570 RGD:35673317 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332
JBrowse link
G Mir30a microRNA 30a onset IEP RGD PMID:32135570 RGD:35673317 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mki67 marker of proliferation Ki-67 IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:30277635 RGD:401938665 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp2 matrix metallopeptidase 2 IEP RGD PMID:24966898 RGD:13207311 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP RGD PMID:24966898 RGD:13207311 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Ncam1 neural cell adhesion molecule 1 sexual_dimorphism
treatment
IEP mRNA:decreased expression:hippocampus (rat)
associated with chronic stress in female rats
RGD PMID:30277635 PMID:27894930 PMID:16207289 RGD:401938665, RGD:401959751, RGD:401959613 NCBI chr 8:49,865,629...50,165,687
Ensembl chr 8:49,865,633...50,166,014
JBrowse link
G Ngf nerve growth factor ISO
IEP
protein:increased expression:serum
protein:decreased expression:brain
RGD PMID:25623403 PMID:15307153 RGD:401965480, RGD:401965482 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Npy neuropeptide Y IAGP
ISO
DNA:deletion:intron:g.4666_4674del (rat)
CTD Direct Evidence: marker/mechanism
DNA:missense mutation: :p.L7P (human)
CTD
RGD
PMID:17572454 PMID:15749341 PMID:12215082 RGD:1357412, RGD:10430830 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Npy2r neuropeptide Y receptor Y2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18828811 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 treatment
sexual_dimorphism
IMP RGD PMID:29437012 PMID:30171933 PMID:33007359 RGD:401965466, RGD:401976281, RGD:401966865 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885
JBrowse link
G Ntf3 neurotrophin 3 ISO
IEP
protein:decreased expression:plasma (human)
protein:increased expression:brain
mRNA,protein:decreased expression:hippocampus, plasma (rat)
RGD PMID:30277635 PMID:15307153 PMID:30277635 RGD:401938665, RGD:401965482, RGD:401938665 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 ISO
IEP
associated with Prenatal Exposure Delayed Effects and anxiety disorder:protein:decreased acetylation:brain RGD PMID:30016666 PMID:8840027 RGD:401959614, RGD:401965407 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Oprd1 opioid receptor, delta 1 IEP
IMP
associated with stress-related disorder; mRNA:decreased expression:dorsal striatum (rat) RGD PMID:28511993 PMID:7501658 RGD:401976432, RGD:401976439 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960
JBrowse link
G Oprk1 opioid receptor, kappa 1 severity
susceptibility
no_association
ISO
IEP
DNA:SNP, haplotype: :rs6473797 (human)
associated with stress-related disorder; mRNA:decreased expression:dorsal striatum (rat)
DNA:SNP: :rs6473797 (human)
DNA:SNP: :rs997917 (human)
RGD PMID:31004399 PMID:28511993 PMID:37177778 PMID:37177778 RGD:401831037, RGD:401976432, RGD:401850581, RGD:401850581 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IMP RGD PMID:11814626 RGD:9835016 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Oprm1 opioid receptor, mu 1 treatment
no_association
ISO CTD Direct Evidence: marker/mechanism
DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human)
DNA:missense mutations, SNP:exon, intron:p.A6V, p.S147C, p.N40D (118A>G) (rs 1799971), IVS2+691G>C (human)
DNA:SNP: :rs510769
CTD
RGD
PMID:12815747 PMID:32772383 PMID:9399694 PMID:26042510 RGD:401827947, RGD:401827934, RGD:401827930 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdyn prodynorphin no_association
susceptibility
ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:hippocampus, granule cell
DNA:SNPs: :rs2281285, rs2225749, rs910080 (human)
DNA:SNP: :rs2281285 (human)
DNA, mRNA:SNP, decreased expression:promoter, dorsolateral prefrontal cortex:rs1997794 (human)
associated with cocaine dependence;DNA, mRNA:SNPs, haplotype:3' utr:rs910080, rs910079, rs2235749 (human)
CTD
RGD
PMID:17559549 PMID:18923396 PMID:1589146 PMID:37177778 PMID:36099111 More... RGD:401851059, RGD:401850581, RGD:401850566, RGD:401850559, RGD:401850550 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Penk proenkephalin IEP mRNA:increased expression:frontal lobe: RGD PMID:22703995 RGD:10003152 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Pomc proopiomelanocortin IEP protein:decreased expression:brain (rat) RGD PMID:18162070 RGD:401976284 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Rpl18a ribosomal protein L18A IEP mRNA:decreased expression:parietal cortex RGD PMID:11244494 RGD:11038708 NCBI chr16:18,542,555...18,544,578
Ensembl chr16:18,542,566...18,545,546
JBrowse link
G Shbg sex hormone binding globulin ISO CTD Direct Evidence: marker/mechanism CTD PMID:8590623 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27219321 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slc6a4 solute carrier family 6 member 4 susceptibility ISO protein:decreased activity: :
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:15520362 PMID:17000009 PMID:20838391 RGD:6480660 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Snca synuclein alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18055133 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Sox2 SRY-box transcription factor 2 IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:30277635 RGD:401938665 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338
JBrowse link
G Spi1 Spi-1 proto-oncogene treatment IEP
IDA
protein:decreased expression:alveolar macrophage RGD PMID:16272341 PMID:21447000 RGD:9586723, RGD:9586725 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
G Spn sialophorin ISO associated with Prenatal Exposure Delayed Effects and anxiety disorder:DNA:Hypermthylation:promoter RGD PMID:30016666 RGD:401959614 NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 severity ISO mRNA,protein:decreased expression:liver: RGD PMID:17697868 RGD:10043133 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
JBrowse link
G Syp synaptophysin sexual_dimorphism IEP associated with chronic stress in female rats RGD PMID:27894930 RGD:401959751 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745
JBrowse link
G Tacr1 tachykinin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19204064 NCBI chr 4:114,920,844...115,089,733
Ensembl chr 4:114,920,844...115,089,733
JBrowse link
G Tacr3 tachykinin receptor 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18422838 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791
JBrowse link
G Tas2r118 taste receptor, type 2, member 118 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16385453 PMID:17250611 NCBI chr 4:52,449,208...52,450,107
Ensembl chr 4:52,449,208...52,450,107
JBrowse link
G Tas2r138 taste receptor, type 2, member 138 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17250611 NCBI chr 4:69,428,344...69,429,339
Ensembl chr 4:69,428,344...69,429,339
JBrowse link
G Tbx19 T-box transcription factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr13:77,450,848...77,484,475
Ensembl chr13:77,450,849...77,504,163
JBrowse link
G Tf transferrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:11000917 PMID:21792595 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tph1 tryptophan hydroxylase 1 ISO RGD PMID:15654285 RGD:1580464 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344
JBrowse link
Alcohol Withdrawal Delirium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 ISO RGD PMID:11841893 RGD:1626329 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Ngf nerve growth factor ISO protein:increased expression:serum RGD PMID:17434673 RGD:401965399 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:16318954 RGD:5688289 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27219321 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
Alcohol Withdrawal Seizures term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1d calcium voltage-gated channel subunit alpha1 D susceptibility IEP mRNA, protein:increased expression:inferior colliculus (rat) RGD PMID:25556199 RGD:152985539 NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215
JBrowse link
G Drd2 dopamine receptor D2 susceptibility ISO DNA:SNP:exon:A>G(human) RGD PMID:23238469 RGD:401959213 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Pdyn prodynorphin ISO mRNA:increased expression:brain RGD PMID:15869750 RGD:401850576 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Slc29a1 solute carrier family 29 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21283641 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27219321 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
alcohol withdrawal syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 no_association
treatment
ISO DNA:SNPs::CYP2C19*2 (681G>A,rs4244285), CYP2C19*3 (636G>A, rs4986893),CYP2C19*17 (-806C>T, rs12248560) (human)
DNA:SNP:promoter:CYP2C19*17 (-806C>T,rs12248560)(human)
DNA:SNP:cds:CYP2C19*2 (681G>A,rs4244285)(human)
RGD PMID:27099220 PMID:30325732 PMID:31957548 RGD:401960863, RGD:401960882, RGD:401960880 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Drd4 dopamine receptor D4 severity ISO DNA:repeats:exon: RGD PMID:20359751 RGD:401959612 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
Alcohol-Induced Disorders, Nervous System term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aif1 allograft inflammatory factor 1 IEP protein:increased expression:cortex, hippocampus (rat) RGD PMID:18585922 RGD:2313030 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Cirbp cold inducible RNA binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:24223948 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818
JBrowse link
alcohol-induced mental disorder term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member ISO CTD Direct Evidence: marker/mechanism CTD PMID:26711020 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Ankk1 ankyrin repeat and kinase domain containing 1 ISO DNA:SNP:exon:rs1800497(human) RGD PMID:18669994 RGD:401959336 NCBI chr 8:49,779,862...49,788,024
Ensembl chr 8:49,779,862...49,788,024
JBrowse link
G Drd2 dopamine receptor D2 ISO DNA:SNP:cds:957C>T(human) RGD PMID:18669994 RGD:401959336 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Foxo4 forkhead box O4 IEP protein:increased phosphorylation:small intestine: RGD PMID:23292333 RGD:10402360 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115
JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:24972622 RGD:10401897 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35713687 NCBI chr12:35,182,165...35,330,935
Ensembl chr12:35,182,154...35,330,987
JBrowse link
Alcohol-Induced Sudden Cardiac Failure term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppa2 inorganic pyrophosphatase 2 ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Sudden cardiac failure, alcohol-induced
OMIM
CTD
ClinVar
PMID:24033266 PMID:25741868 PMID:27523597 PMID:27523598 PMID:28492532 More... NCBI chr 2:221,800,791...221,878,079
Ensembl chr 2:221,800,842...221,878,081
JBrowse link
Alcohol-Related Disorders term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor IEP protein:altered expression:brain RGD PMID:10837897 RGD:401965408 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Cartpt CART prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:22823101 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
JBrowse link
G Casp8 caspase 8 treatment IEP RGD PMID:30118883 RGD:13782287 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Ngf nerve growth factor IEP protein:altered expression:brain RGD PMID:10837897 RGD:401965408 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Oprk1 opioid receptor, kappa 1 treatment IDA RGD PMID:20962231 RGD:401850591 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
alcoholic cardiomyopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO GAD PMID:15118671 RGD:1331525 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:22497828 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Nos1 nitric oxide synthase 1 IEP protein:decreased expression:skeletal muscle, membrane RGD PMID:17607508 RGD:1642138 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP protein:increased expression:heart myocardium RGD PMID:18783396 RGD:2301868 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rxra retinoid X receptor alpha IEP RGD PMID:19791468 RGD:2317465 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Slc25a4 solute carrier family 25 member 4 IEP mRNA, protein:decreased expression:myocardium RGD PMID:21169901 RGD:9681464 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
Alcoholic Fatty Liver term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:plasma RGD PMID:16115302 RGD:5686674 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adipor2 adiponectin receptor 2 treatment IEP
ISO
RGD PMID:26115886 PMID:18755807 PMID:27220557 PMID:22013387 RGD:25330099, RGD:25824943, RGD:25824939, RGD:25440493 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member severity
treatment
susceptibility
IDA
ISO
human transgene in mouse model
protein:altered processing:liver (mouse)
DNA:missense mutation:cds:p.E504K (human)
RGD PMID:17058263 PMID:25457208 PMID:29156373 PMID:29063269 RGD:1599041, RGD:15036811, RGD:15036805, RGD:14696776 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Arrb2 arrestin, beta 2 ameliorates ISO protein:increased expression:hepatocyte RGD PMID:33871024 PMID:33871024 RGD:401938594, RGD:401938594 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 ISO protein:increased expression:liver (human) RGD PMID:29307797 RGD:153297819 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G C1qc complement C1q C chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:35789393 NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment ISO RGD PMID:25557254 RGD:14995489 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 treatment ISO RGD PMID:25557254 RGD:14995489 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 disease_progression ISO RGD PMID:27859576 RGD:14401742 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:24280415 RGD:11041117 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Crp C-reactive protein IEP protein:increased expression:serum: RGD PMID:21806828 RGD:9491781 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Ctsb cathepsin B IEP protein:increased activity:liver, cytosol (rat) RGD PMID:17850215 RGD:2315516 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:26428356 PMID:25583360 PMID:24064383 RGD:14700884, RGD:14700870 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO RGD PMID:22905112 RGD:9588654 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Hamp hepcidin antimicrobial peptide IEP mRNA:decreased expression:liver RGD PMID:19253830 RGD:11041633 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Ldlr low density lipoprotein receptor IEP protein:decreased expression: liver (rat) RGD PMID:20028367 RGD:21410185 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:26867493 RGD:25671474 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Nlrc5 NLR family, CARD domain containing 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36708882 NCBI chr19:10,477,638...10,581,023
Ensembl chr19:10,477,628...10,562,121
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 treatment IMP RGD PMID:26256083 RGD:11522097 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Pemt phosphatidylethanolamine N-methyltransferase IEP RGD PMID:17156888 RGD:1642369 NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:18703563 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Serpine1 serpin family E member 1 IEP mRNA:increased expression:liver (rat) RGD PMID:25561792 RGD:11075083 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinf1 serpin family F member 1 IEP protein:decreased expression:liver RGD PMID:18996124 RGD:2312349 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19951287 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 IEP RGD PMID:11477087 RGD:1625694 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Stat4 signal transducer and activator of transcription 4 IEP RGD PMID:18296740 RGD:7207884 NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Tlr4 toll-like receptor 4 severity ISO RGD PMID:29884546 PMID:21463341 RGD:14697697, RGD:14700554 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor susceptibility
treatment
ISO
IEP
DNA:SNP:promoter:-238G>A (human) RGD PMID:9214463 PMID:20143470 RGD:14995434, RGD:38508901 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
alcoholic hepatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Agt angiotensinogen ISO mRNA:decreased expression:liver RGD PMID:17258719 RGD:1601135 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Alb albumin severity ISO protein:increased expression, modification:urine RGD PMID:29369844 RGD:14694842 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 severity ISO RNA:increased expression:liver: RGD PMID:24429361 PMID:21826694 PMID:10446112 RGD:14975280, RGD:14995491, RGD:14995467 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 severity ISO RGD PMID:10446112 RGD:14995467 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12586603 PMID:31258651 RGD:14995304 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO RGD PMID:1670041 RGD:5688335 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 disease_progression
severity
ISO mRNA:increased expression:liver (mouse)
mRNA:increased expression:liver (human)
RGD PMID:33173221 PMID:33173221 RGD:151347691, RGD:151347691 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Fas Fas cell surface death receptor treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fgf19 fibroblast growth factor 19 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287
JBrowse link
G Icam1 intercellular adhesion molecule 1 severity ISO protein:increased expression:hepatocyte RGD PMID:1347281 RGD:14402038 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il13 interleukin 13 IEP mRNA:increased expression:liver RGD PMID:16698589 RGD:1581860 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il18 interleukin 18 severity ISO associated alcoholic liver cirrhosis; protein:increased expression:plasma: RGD PMID:15566508 RGD:14696666 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Mir155 microRNA 155 IEP RNA:increased expression:liver RGD PMID:32317960 RGD:151347420 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Slc10a1 solute carrier family 10 member 1 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Socs1 suppressor of cytokine signaling 1 IEP mRNA:decreased expression:liver RGD PMID:32317960 RGD:151347420 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 treatment IEP RGD PMID:27939985 RGD:15036816 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Sts steroid sulfatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:26220752 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26220752 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Tnf tumor necrosis factor treatment ISO
IEP
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:12586603 PMID:27939985 RGD:15036816 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
Alcoholic Intoxication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arc activity-regulated cytoskeleton-associated protein disease_progression ISO mRNA:altered expression:brain (mouse) RGD PMID:26708208 RGD:401853772 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO mRNA,protein:decreased expression:cerebellum RGD PMID:19861148 RGD:401965398 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Drd2 dopamine receptor D2 treatment IDA RGD PMID:28300818 RGD:13506954 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Ifng interferon gamma treatment ISO RGD PMID:9514301 RGD:10755766 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Ngf nerve growth factor ISO mRNA,protein:increased expression:cerebellum
protein:increased expression:plasma
RGD PMID:19861148 PMID:18639986 RGD:401965398, RGD:401965411 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Nps neuropeptide S IDA RGD PMID:19860802 RGD:9831199 NCBI chr 1:190,077,040...190,080,821
Ensembl chr 1:190,077,040...190,080,821
JBrowse link
G Npsr1 neuropeptide S receptor 1 IEP mRNA:increased expression:brain RGD PMID:19860802 RGD:9831199 NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 ISO mRNA,protein:increased expression:cerebellum RGD PMID:19861148 RGD:401965398 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Per2 period circadian regulator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15608650 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
alcoholic liver cirrhosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility ISO DNA:missense mutation:cds:p.E504K (human)
DNA:missense mutation:cds: (rs671) (human)
associated with alcohol dependence;DNA:missense mutation:exon 12:p.E487K (human)
RGD PMID:29779728 PMID:23550892 PMID:11051375 RGD:14696777, RGD:15042864, RGD:15042858 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase ISO protein:decreased expression:brain RGD PMID:16205370 RGD:6483345 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Crp C-reactive protein severity ISO RGD PMID:22441510 RGD:6482305 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:20843640 PMID:29404441 RGD:14700873 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 severity ISO mRNA:increased expression:liver (human) RGD PMID:33173221 RGD:151347691 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 disease_progression
ameliorates
IEP
IMP
RGD PMID:21199726 PMID:23409069 RGD:150429766, RGD:150517731 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Fabp2 fatty acid binding protein 2 onset ISO DNA:polymorphism:CDS:amino acid A54T, homozygosity of the T allele associated with later onset RGD PMID:16289894 PMID:16289894 RGD:1578455, RGD:1578455 NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
JBrowse link
G Il18bp interleukin 18 binding protein ISO protein:increased expression:plasma: RGD PMID:15566508 RGD:14696666 NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963
JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jak2 Janus kinase 2 ISO mRNA, protein:increased expression, increased tyrosine phosphorylation:liver RGD PMID:24619965 RGD:10403061 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Lep leptin IDA DNA:hypomethylation:promoter (human) RGD PMID:29912265 RGD:21201248 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Mboat7 membrane bound O-acyltransferase domain containing 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26482880 NCBI chr 1:65,525,206...65,539,538
Ensembl chr 1:65,525,213...65,539,538
JBrowse link
G Mir122 microRNA 122 ISO miRNA:decreased expression:liver RGD PMID:28987423 RGD:14401600 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir141 microRNA 141 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
JBrowse link
G Mir17 microRNA 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir193b microRNA 193b ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:1,317,742...1,317,824
Ensembl chr10:1,317,742...1,317,824
JBrowse link
G Mir423 microRNA 423 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mir484 microRNA 484 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr10:887,684...887,760
Ensembl chr10:887,684...887,760
JBrowse link
G Mir532 microRNA 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr  X:15,247,315...15,247,393
Ensembl chr  X:15,247,315...15,247,393
JBrowse link
G Mir93 microRNA 93 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28545106 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
JBrowse link
G Mmp13 matrix metallopeptidase 13 IEP RGD PMID:16286264 RGD:10043176 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19731237 PMID:23274713 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility ISO DNA:SNP: :677C>T(human) RGD PMID:25987440 RGD:14696749 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 ISO RGD PMID:24497272 RGD:10448995 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Plau plasminogen activator, urokinase IDA RGD PMID:19615318 RGD:7241800 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19946271 PMID:26482880 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Serpine1 serpin family E member 1 susceptibility ISO DNA:polymorphism:promoter: RGD PMID:25987440 RGD:14696749 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinf1 serpin family F member 1 ISO protein:increased expression:serum (human) RGD PMID:27748324 RGD:27226704 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link
G Smad3 SMAD family member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Sod2 superoxide dismutase 2 susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP: : 47T>C(human)
CTD
RGD
PMID:19731237 PMID:26873981 RGD:11060603 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tlr9 toll-like receptor 9 ISO protein:increased expression:blood, neutrophil (human) RGD PMID:18433921 RGD:5130706 NCBI chr 8:106,864,680...106,868,796
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tm6sf2 transmembrane 6 superfamily member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26482880 NCBI chr16:19,344,218...19,351,431
Ensembl chr16:19,344,222...19,351,431
JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:23274713 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
Alcoholic Liver Diseases term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme severity
treatment
ISO protein:increased activity:serum (human) RGD PMID:3028446 PMID:28691216 RGD:19165343, RGD:40400719 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Adipor2 adiponectin receptor 2 treatment IEP RGD PMID:24797033 RGD:25824940 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member susceptibility
severity
ISO DNA:missense mutation:cds, exon 12:p.E487K (human)
DNA:polymorphism:exon 12: (human)
DNA:deletion:cds: (mouse)
RGD PMID:1916152 PMID:12198368 PMID:26173414 PMID:3189338 RGD:14696699, RGD:14981580, RGD:11076022, RGD:14696790 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Angpt2 angiopoietin 2 severity ISO RGD PMID:24959006 RGD:15014784 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
JBrowse link
G C6 complement C6 resistance IAGP RGD PMID:15351314 RGD:1600673 NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275
JBrowse link
G Cav1 caveolin 1 treatment IEP RGD PMID:23764359 RGD:8662277 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cd27 CD27 molecule IEP RGD PMID:16698589 RGD:1581860 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
JBrowse link
G Cd59b CD59b molecule IEP protein:decreased expression:liver RGD PMID:12483994 RGD:1600486 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 susceptibility ISO DNA:SNP::-318 T>C(rs5742909)(human) RGD PMID:15208156 RGD:14398728 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP mRNA:increased expression:liver RGD PMID:10498645 RGD:5135271 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP mRNA:increased expression:liver RGD PMID:10498645 RGD:5135271 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IEP mRNA:increased expression:liver RGD PMID:10498645 RGD:5135271 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 treatment ISO
IEP
RGD PMID:29401608 PMID:30192013 PMID:25592162 PMID:29902864 RGD:14700887, RGD:14700906, RGD:14700894, RGD:14700893 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Egfr epidermal growth factor receptor ISO RGD PMID:30502657 RGD:38599215 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA RGD PMID:21059295 RGD:10395351 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Fas Fas cell surface death receptor ISO protein:increased expression:lymphocyte: RGD PMID:26429926 RGD:14700711 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO RGD PMID:15932176 PMID:26937962 RGD:14700973, RGD:11060494 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO RGD PMID:15932176 PMID:26937962 RGD:14700973, RGD:11060494 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Hfe homeostatic iron regulator IEP mRNA:increased expression:liver, Kupffer cell (rat) RGD PMID:18599584 RGD:8694397 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP mRNA:increased expression:liver (rat) RGD PMID:17085342 RGD:9068897 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Igf2 insulin-like growth factor 2 IEP mRNA:increased expression:liver RGD PMID:18505416 RGD:5510002 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
G Il1b interleukin 1 beta IEP protein:increased expression:serum (rat) RGD PMID:23009062 RGD:7204488 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO mRNA:decreased expression:liver (human) RGD PMID:22459801 RGD:6892954 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Lpl lipoprotein lipase treatment IEP RGD PMID:28442378 RGD:13794376 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mif macrophage migration inhibitory factor IEP protein:increased expression:liver RGD PMID:11798463 RGD:1642007 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mir122 microRNA 122 ISO miRNA:decreased expression:hepatocyte RGD PMID:28987423 RGD:14401600 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:28492308 RGD:25314298 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
JBrowse link
G Mir223 microRNA 223 severity ISO RGD PMID:27679493 RGD:21408575 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP protein:increased expression:liver RGD PMID:17374579 RGD:1642042 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor disease_progression
severity
ISO mRNA:increased expression:liver RGD PMID:26576483 PMID:26576483 RGD:14695016, RGD:14695016 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Nedd8 NEDD8 ubiquitin like modifier ISO RGD PMID:12533840 RGD:1549458 NCBI chr15:29,153,556...29,165,575
Ensembl chr15:29,153,556...29,166,160
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment
severity
ISO DNA:SNP:promoter:rs35652124(human) RGD PMID:31906014 PMID:31340446 RGD:21201307, RGD:21201311 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Otc ornithine transcarbamylase IEP protein:increased expression:serum (rat) RGD PMID:19101528 RGD:4144059 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918
JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO protein:increased expression:serum RGD PMID:22098627 RGD:6484116 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19946271 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha severity ISO DNA:knockout::increased severity in knockouts (mouse) RGD PMID:15382117 RGD:5683636 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27765815 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 IEP protein:decreased expression:liver, cytosolic proteasome complex (rat) RGD PMID:19609968 RGD:9480236 NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076
JBrowse link
G Rbp4 retinol binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16762690 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Slc39a13 solute carrier family 39 member 13 IEP protein:increased expression:liver, endoplasmic reticulum (rat) RGD PMID:25767260 RGD:11553884 NCBI chr 3:77,039,411...77,047,528
Ensembl chr 3:77,037,565...77,049,226
JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO human gene in a rat model RGD PMID:11266387 RGD:9587792 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 treatment ISO RGD PMID:32236798 RGD:27095880 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18703563 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Tbxas1 thromboxane A synthase 1 IEP mRNA,protein:increased expression:liver, Kupffer cell: RGD PMID:9262373 RGD:11059607 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
JBrowse link
G Tert telomerase reverse transcriptase ISO mRNA,protein,activity:increased expression, increased activity:kupffer cell: RGD PMID:26725521 RGD:11574970 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tlr3 toll-like receptor 3 treatment ISO RGD PMID:23023014 PMID:30870678 RGD:21079426, RGD:21079436 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tnf tumor necrosis factor treatment IMP
IEP
mRNA:increased expression:liver (rat) RGD PMID:9397994 PMID:7556590 PMID:15670576 RGD:14398736, RGD:14995472, RGD:14995456 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 IEP protein:decreased expression:liver, cytosolic proteasome complex RGD PMID:19609968 RGD:9480236 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502
JBrowse link
G Vegfa vascular endothelial growth factor A ISO protein:increased expression:plasma RGD PMID:24959006 RGD:15014784 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
alcoholic neuropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf1 insulin-like growth factor 1 IEP RGD PMID:23016131 RGD:10402569 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP RGD PMID:23016131 RGD:10402569 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igf2 insulin-like growth factor 2 IEP RGD PMID:23016131 RGD:10402569 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018
JBrowse link
alcoholic pancreatitis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr CF transmembrane conductance regulator ISO DNA:missense mutations: :p.L1156F, Q1352H (human) RGD PMID:26089335 RGD:11566036 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Pthlh parathyroid hormone-like hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:22280800 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C ISO DNA:polymorphisms: :p.N129K, p.R131K, p.W208R (human) RGD PMID:12806614 RGD:2317503 NCBI chr 9:88,739,577...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
alcoholic psychosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2a 5-hydroxytryptamine receptor 2A ISO DNA:SNP:promoter:-1438G>A RGD PMID:11842624 RGD:401900738 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
amphetamine abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16470869 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
JBrowse link
G Adora2a adenosine A2a receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:20799992 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Ak5 adenylate kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 2:241,397,297...241,581,483
Ensembl chr 2:241,397,297...241,581,458
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15982448 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Aoah acyloxyacyl hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr17:43,808,110...44,049,458
Ensembl chr17:43,809,638...44,049,148
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein disease_progression ISO mRNA:increased expression:brain (mouse) RGD PMID:25959066 RGD:401938592 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Arrb2 arrestin, beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17233643 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850
JBrowse link
G Astn2 astrotactin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:78,758,142...79,744,021
Ensembl chr 5:78,758,142...79,748,273
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO
IEP
CTD Direct Evidence: marker/mechanism
protein:decreased expression:hippocampus
CTD
RGD
PMID:20736000 PMID:24407463 RGD:401976437 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Cchcr1 coiled-coil alpha-helical rod protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr20:3,205,675...3,218,437
Ensembl chr20:3,205,676...3,218,308
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831
JBrowse link
G Cdh13 cadherin 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
JBrowse link
G Cdk5 cyclin-dependent kinase 5 ISO protein:increased expression:ventral tegmental area, nucleus accumbens (mouse) RGD PMID:28782589 RGD:401900303 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cfh complement factor H ISO
IEP
protein:increased expression:serum:
protein:increased expression:serum, hippocampus:
RGD PMID:22871478 PMID:22871478 RGD:7364944, RGD:7364944 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Col28a1 collagen type XXVIII alpha 1 chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 4:36,069,980...36,223,128
Ensembl chr 4:36,069,970...36,223,220
JBrowse link
G Comt catechol-O-methyltransferase susceptibility ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:cd: p.V158M (human)
DNA:SNPs,haplotypes:exon,3'utr: (rs4680, rs165599) (human)
ClinVar Annotator: match by term: methamphetamine use disorder
CTD
ClinVar
RGD
PMID:15274053 PMID:25741868 PMID:33544778 PMID:21934638 PMID:17187009 More... RGD:401959602, RGD:401940147, RGD:401940150, RGD:401940124 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment ISO
IEP
protein:increases activity:ventral tegmental area, nucleus accumbens (mouse)
protein:increased expression, increased phosphorylation:nucleus accumbens, ventral tegmental area
RGD PMID:28782589 PMID:31900897 RGD:401900303, RGD:401938636 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Csmd1 CUB and Sushi multiple domains 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr16:72,218,189...73,818,380
Ensembl chr16:72,218,503...73,817,614
JBrowse link
G Cubn cubilin ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18280655 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078
JBrowse link
G Drd1 dopamine receptor D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18363855 PMID:19444617 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18363855 PMID:18555060 PMID:19940168 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19940168 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15274053 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Ephx1 epoxide hydrolase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19598248 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
JBrowse link
G Fkbp15 FKBP prolyl isomerase family member 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:75,750,786...75,815,038
Ensembl chr 5:75,750,787...75,814,990
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19689456 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO
IEP
protein:increased expression:ventral tegmental area, nucleus accumbens (mouse)
associated with stress related disorder;protein:increased expression:brain (rat)
RGD PMID:28782589 PMID:27672362 PMID:31373119 RGD:401900303, RGD:401901183, RGD:401900735 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 susceptibility ISO DNA:SNPs, halotypes:intron (rs2076483,rs29221,rs715044) (human) RGD PMID:30143926 RGD:401940101 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15772696 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gad1 glutamate decarboxylase 1 susceptibility ISO DNA:haplotype: :rs769404���rs701492(human) RGD PMID:27967329 RGD:401900122 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gad2 glutamate decarboxylase 2 susceptibility ISO DNA:SNP: :rs2236418(human) RGD PMID:27967329 RGD:401900122 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17356005 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Grm2 glutamate metabotropic receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20211215 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
JBrowse link
G Gstm1 glutathione S-transferase mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19254865 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15729709 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18186040 PMID:19254865 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Hdac8 histone deacetylase 8 IEP mRNA:decreased expression:striatum (rat) RGD PMID:25452209 RGD:9681719 NCBI chr  X:67,385,288...67,593,014
Ensembl chr  X:67,385,289...67,592,923
JBrowse link
G Hs3st4 heparan sulfate-glucosamine 3-sulfotransferase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 1:178,539,078...178,944,850
Ensembl chr 1:178,539,093...178,944,107
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B ISO CTD Direct Evidence: therapeutic CTD PMID:10780831 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19689456 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20705401 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912
JBrowse link
G Large1 LARGE xylosyl- and glucuronyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr19:11,603,129...12,048,930
Ensembl chr19:11,603,129...12,048,930
JBrowse link
G Lingo2 leucine rich repeat and Ig domain containing 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:50,370,744...51,687,252
Ensembl chr 5:50,367,101...50,516,956
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983
JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796
JBrowse link
G Mtarc2 mitochondrial amidoxime reducing component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr13:96,362,810...96,397,284 JBrowse link
G Myo5b myosin Vb ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr18:68,038,759...68,341,568
Ensembl chr18:68,038,759...68,338,745
JBrowse link
G Nos1 nitric oxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15542708 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Npy1r neuropeptide Y receptor Y1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19566775 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
JBrowse link
G Nrg1 neuregulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Oprm1 opioid receptor, mu 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16402083 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G PCOLCE2 procollagen C-endopeptidase enhancer 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 8:96,193,461...96,251,116
Ensembl chr 8:96,193,461...96,251,114
JBrowse link
G Pde4b phosphodiesterase 4B ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pde4d phosphodiesterase 4D ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
G Pde6c phosphodiesterase 6C ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315
JBrowse link
G Pdyn prodynorphin ISO
IEP
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:nucleus acccumbens
mRNA:increased expression:nucleus accumbens
mRNA:increased expression:central amygdaloid nucleus
mRNA:altered expression:brain
DNA:repeat:promoter:rs35286251 (human)
CTD
RGD
PMID:16529859 PMID:27989838 PMID:22390687 PMID:12523490 PMID:16289352 More... RGD:401851910, RGD:401851043, RGD:401850585, RGD:401850564, RGD:401850552 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Pick1 protein interacting with PRKCA 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17606663 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848
JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:15659235 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Pou5f1 POU class 5 homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Prdm2 PR/SET domain 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha treatment IEP protein:increased expression, increased phosphorylation:nucleus accumbens, ventral tegmental area RGD PMID:31900897 RGD:401938636 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Prokr2 prokineticin receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20576534 NCBI chr 3:119,624,738...119,639,442
Ensembl chr 3:119,627,601...119,635,718
JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr16:21,465,643...22,035,846
Ensembl chr16:21,465,639...22,034,547
JBrowse link
G Raly RALY heterogeneous nuclear ribonucleoprotein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 3:143,306,039...143,370,542
Ensembl chr 3:143,306,300...143,370,539
JBrowse link
G Rapgef5 Rap guanine nucleotide exchange factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 6:138,445,184...138,679,943
Ensembl chr 6:138,437,991...138,679,936
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:19689456 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rgs17 regulator of G-protein signaling 17 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 1:42,222,248...42,324,625
Ensembl chr 1:42,227,070...42,324,609
JBrowse link
G Serpina5 serpin family A member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 6:123,009,224...123,028,412
Ensembl chr 6:123,023,306...123,028,407
JBrowse link
G Sgcz sarcoglycan zeta ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr16:53,660,283...54,740,811
Ensembl chr16:53,660,502...54,735,193
JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr20:26,765,278...27,099,261
Ensembl chr20:26,765,015...27,099,257
JBrowse link
G Slc6a3 solute carrier family 6 member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12931138 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slc6a4 solute carrier family 6 member 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19689456 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
JBrowse link
G Slc6a9 solute carrier family 6 member 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17582620 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Smyd3 SET and MYND domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr13:90,709,263...91,266,209
Ensembl chr13:90,709,270...91,266,253
JBrowse link
G Snca synuclein alpha treatment IMP
ISO
CTD Direct Evidence: marker/mechanism CTD
RGD
PMID:15542733 PMID:32278788 PMID:20551914 RGD:13506280 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Trpm3 transient receptor potential cation channel, subfamily M, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 1:219,673,200...220,557,610
Ensembl chr 1:219,672,892...220,560,717
JBrowse link
G Usp48 ubiquitin specific peptidase 48 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr 5:149,800,189...149,867,838
Ensembl chr 5:149,800,179...149,867,719
JBrowse link
G Zfp385d zinc finger protein 385D ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr15:5,040,182...5,849,975
Ensembl chr15:5,042,572...5,423,367
JBrowse link
G Zfp423 zinc finger protein 423 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18316681 NCBI chr19:19,111,213...19,407,373
Ensembl chr19:19,110,238...19,407,373
JBrowse link
Binge Drinking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 ISO
IEP
protein:increased expression, increased nitration RGD PMID:25236742 PMID:29404485 PMID:25236742 RGD:14700891, RGD:14700911, RGD:14700891 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO protein:increased expression:nucleus accumbens: RGD PMID:23423140 RGD:9588287 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Drd4 dopamine receptor D4 susceptibility ISO DNA:repeats:exon: RGD PMID:19393859 RGD:401960068 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Efhd2 EF-hand domain family, member D2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28397836 NCBI chr 5:154,160,945...154,176,980
Ensembl chr 5:154,160,946...154,176,980
JBrowse link
G Gpx1 glutathione peroxidase 1 IEP protein:decreased expression:liver RGD PMID:25864381 RGD:401827870 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx3 glutathione peroxidase 3 IEP protein:decreased expression:serum RGD PMID:25864381 RGD:401827870 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gpx4 glutathione peroxidase 4 IEP protein:decreased expression:liver RGD PMID:25864381 RGD:401827870 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Mir125a microRNA 125a IEP RNA:decreased expression:neuron RGD PMID:27085842 RGD:26884454 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
G Mir223 microRNA 223 ISO RNA:increased expression:serum
RNA:increased expression:serum, neutrophil,liver
RGD PMID:27679493 PMID:27679493 RGD:21408575, RGD:21408575 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 ISO RGD PMID:29197086 RGD:14348965 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
G Sirt1 sirtuin 1 IEP RGD PMID:24416161 RGD:9495933 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc23a2 solute carrier family 23 member 2 IEP RGD PMID:27085842 RGD:26884454 NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
JBrowse link
cannabis abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19625010 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21041608 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Apol2 apolipoprotein L, 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558
JBrowse link
G Bche butyrylcholinesterase ISO protein:increased activity:blood plasma (human) RGD PMID:30707402 RGD:401960085 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Calm1 calmodulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19016476 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Comt catechol-O-methyltransferase susceptibility
onset
ISO DNA:SNP:cd: p.V158M (human)
associated with alcohol use disorder; DNA:hypermethylation:promoter
RGD PMID:19259017 PMID:33781176 PMID:30790675 RGD:401959590, RGD:401959741, RGD:401959592 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Drd4 dopamine receptor D4 susceptibility ISO DNA:duplication:promoter: 120bp repeat RGD PMID:33544778 RGD:401959602 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 4:57,030,817...57,042,682
Ensembl chr 4:57,032,314...57,042,663
JBrowse link
G Ngf nerve growth factor ISO protein:decreased expression:serum RGD PMID:18774699 RGD:401965396 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Scarb1 scavenger receptor class B, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
cannabis dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A susceptibility ISO DNA:SNP: :3435C>T (rs1045642) (human) RGD PMID:19625010 RGD:401901192 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Comt catechol-O-methyltransferase ISO DNA:hypermethylation:promoter RGD PMID:24902721 RGD:401940112 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Hcrt hypocretin neuropeptide precursor ISO mRNA:increased expression:blood (human) RGD PMID:22846875 RGD:401960066 NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210
JBrowse link
cocaine abuse term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase severity ISO RGD PMID:21540357 RGD:401960084 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 severity ISO RGD PMID:21806491 RGD:401794583 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Cd40lg CD40 ligand severity ISO RGD PMID:21806491 RGD:401794583 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit onset ISO DNA:SNP:exon:rs16969968(human) RGD PMID:32841724 RGD:150530292 NCBI chr 8:55,369,794...55,398,526
Ensembl chr 8:55,369,794...55,398,146
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit onset ISO DNA:SNP::rs950776(human) RGD PMID:32841724 RGD:150530292 NCBI chr 8:55,417,583...55,437,027
Ensembl chr 8:55,418,313...55,437,027
JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO
IDA
protein:increased expression, increased phosphorylation:prefrontal cortex RGD PMID:24205196 PMID:18001273 RGD:401940185, RGD:401959587 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit IEP associated with alcohol dependence;protein:increased expression: caudate-putamen (rat) RGD PMID:17572394 RGD:401900302 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Hcrt hypocretin neuropeptide precursor treatment ISO RGD PMID:29454841 RGD:401960065 NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A IEP protein:decreased expression:dentate gyrus, hypothalamus RGD PMID:9723786 RGD:401900605 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A treatment IEP
IMP
mRNA:increased expression:orbitofrontal cortex RGD PMID:27733540 PMID:20814782 PMID:11259563 RGD:401900753, RGD:401901179, RGD:401900755 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C treatment IMP RGD PMID:20814782 RGD:401901179 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA protein:increased phosphorylation:nucleus accumbens RGD PMID:25522720 RGD:401851063 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IDA protein:increased phosphorylation:nucleus accumbens RGD PMID:25522720 RGD:401851063 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 treatment IMP RGD PMID:12805318 PMID:9765324 RGD:401976288, RGD:401976376 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Pdyn prodynorphin IEP mRNA:increased expression:caudate putamen
mRNA:increased expression:central amygdaloid nucleus, dentate gyrus of hippocampal formation
RGD PMID:7694032 PMID:12523490 RGD:401850578, RGD:401850585 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
cocaine dependence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankk1 ankyrin repeat and kinase domain containing 1 treatment ISO DNA:SNP: :rs1800497(human) RGD PMID:23635803 RGD:401959203 NCBI chr 8:49,779,862...49,788,024
Ensembl chr 8:49,779,862...49,788,024
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein ISO protein:increased expression:dorsal striatum, shell of nucleus accumbens (mouse) RGD PMID:27567310 RGD:401901591 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Bdnf brain-derived neurotrophic factor ISO RGD PMID:14973246 RGD:401965389 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV no_association ISO DNA:SNP: :rs919334
DNA:SNPs: :rs1457115, rs9285875
RGD PMID:19001277 PMID:19001277 RGD:401938643, RGD:401938643 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Ccser1 coiled-coil serine-rich protein 1 susceptibility ISO DNA:SNP:: (rs1381355) (human) RGD PMID:18438686 RGD:401851917 NCBI chr 4:90,153,873...91,391,441
Ensembl chr 4:90,292,780...91,388,786
JBrowse link
G Comt catechol-O-methyltransferase susceptibility ISO DNA:SNPs,haplotypes:exon: p.V158M (rs4680, rs737865, rs165688) (human) RGD PMID:18704099 RGD:401959302 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment
sexual_dimorphism
no_association
IEP
IDA
ISO
protein:increased phosphorylation:nucleus accumbens
protein:increased phosphorylation:nucleus accumbens, prefrontal cortex
DNA:SNPs: :rs10876469, rs2177000
RGD PMID:27664298 PMID:25522720 PMID:23665060 PMID:19001277 RGD:401900166, RGD:401851063, RGD:401851078, RGD:401938643 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Drd2 dopamine receptor D2 sexual_dimorphism
treatment
IMP
ISO
female only;DNA:SNP: :rs2283265(human) RGD PMID:29454035 PMID:30367264 PMID:23635803 RGD:13506950, RGD:401959597, RGD:401959203 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit treatment
ameliorates
IEP
ISO
protein:increased expression:Nucleus Accumbens, Caudate Putamen (rat)
protein:increased expression:dorsal striatum, nucelus accumbens (mouse)
mRNA,protein:increased expression:Nucleus Accumbens, Caudate Putamen (rat)
protein:increased expression:Brain (rat)
RGD PMID:25522720 PMID:27380261 PMID:20633205 PMID:27664298 PMID:22403532 More... RGD:401851063, RGD:401901287, RGD:401900126, RGD:401900166, RGD:401851084, RGD:401851078 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 susceptibility ISO DNA:SNP:intron: C>G (rs29220) (human)
mRNA:decreased expression:hippocampus (human)
RGD PMID:22253714 PMID:26727527 RGD:401900163, RGD:11552767 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gad1 glutamate decarboxylase 1 ISO mRNA:decreased expression:hippocampus RGD PMID:22253714 RGD:401900163 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gad2 glutamate decarboxylase 2 ISO mRNA:decreased expression:hippocampus RGD PMID:22253714 RGD:401900163 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A treatment ISO
IMP
DNA:SNP: :rs6561333 RGD PMID:23241418 PMID:15849375 PMID:23336050 RGD:401900299, RGD:401900756, RGD:401900743 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C treatment IMP RGD PMID:23336050 RGD:401900743 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287
JBrowse link
G Klhl5 kelch-like family member 5 susceptibility ISO DNA:SNP:: (rs1046655) (human) RGD PMID:18438686 RGD:401851917 NCBI chr14:43,144,254...43,206,192
Ensembl chr14:43,144,257...43,184,238
JBrowse link
G Lrrc7 leucine rich repeat containing 7 susceptibility ISO DNA:SNP: (rs1938584) (human) RGD PMID:18438686 RGD:401851917 NCBI chr 2:247,146,616...247,634,945
Ensembl chr 2:247,147,752...247,634,547
JBrowse link
G Manea mannosidase, endo-alpha susceptibility ISO DNA:SNPs:multiple RGD PMID:19255376 RGD:401851915 NCBI chr 5:40,196,373...40,218,540
Ensembl chr 5:40,196,396...40,218,459
JBrowse link
G Mapk1 mitogen activated protein kinase 1 IDA protein:increased phosphorylation:brain RGD PMID:23665060 RGD:401851078 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 IDA protein:increased phosphorylation:brain RGD PMID:23665060 RGD:401851078 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Ngf nerve growth factor ISO protein:decreased expression:serum RGD PMID:17715210 RGD:401976440 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
JBrowse link
G Oprk1 opioid receptor, kappa 1 ISO DNA:SNPs:intron:rs6473797, rs10111937 RGD PMID:34843875 RGD:401851040 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823
JBrowse link
G Oprm1 opioid receptor, mu 1 ISO mRNA:increased expression:nucleus accumbens RGD PMID:29992335 RGD:401831041 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409
JBrowse link
G Pdyn prodynorphin susceptibility ISO DNA, mRNA:SNPs, haplotype:3' utr:rs910080, rs910079, rs2235749 (human)
mRNA:increased expression:nucleus accumbens
mRNA:increased expression:caudate-putamen
DNA:VNTR:Promoter
RGD PMID:18923396 PMID:22390687 PMID:23164614 PMID:16184603 RGD:401850550, RGD:401851043, RGD:401850589, RGD:401850583 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Ppbp pro-platelet basic protein ISO protein:increased expression:plasma RGD PMID:21806491 RGD:401794583 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Prl prolactin severity ISO protein:decreased expression:blood serum (human)
protein:increased expression:blood plasma (human)
protein:increased expression:blood serum (human)
RGD PMID:16915581 PMID:2243892 PMID:15064918 RGD:401959377, RGD:401960099, RGD:401959381 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Sirt1 sirtuin 1 IEP protein:increased expression:brain, nucleus accumbens (rat) RGD PMID:27664298 RGD:401900166 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sirt2 sirtuin 2 treatment IEP RGD PMID:27664298 RGD:401900166 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975
JBrowse link
G Tenm3 teneurin transmembrane protein 3 susceptibility ISO DNA:SNP:: (rs1514483) (human) RGD PMID:18438686 RGD:401851917 NCBI chr16:41,251,909...43,978,594
Ensembl chr16:41,252,182...43,978,594
JBrowse link
Cocaine-Related Disorders term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase treatment IMP RGD PMID:22128851 RGD:9588542 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Ago2 argonaute RISC catalytic component 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20643829 NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974
JBrowse link
G Apol2 apolipoprotein L, 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18311559 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Atp9b ATPase phospholipid transporting 9B (putative) ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr18:74,176,863...74,368,993
Ensembl chr18:74,176,863...74,368,953
JBrowse link
G Bche butyrylcholinesterase ISO CTD Direct Evidence: therapeutic CTD PMID:18292872 PMID:18514640 PMID:20060817 PMID:20971807 PMID:22935511 More... NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bdnf brain-derived neurotrophic factor severity
susceptibility
ISO
IMP
CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:14973246 PMID:17618281 PMID:17651427 PMID:18311559 PMID:19321768 More... RGD:38501054, RGD:38501054 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bdnfem1Sage brain-derived neurotrophic factor; ZFN induced mutant 1, Sage severity IMP RGD PMID:23583595 RGD:38501054
G Calm1 calmodulin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
JBrowse link
G Calm2 calmodulin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:14725635 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV ISO CTD Direct Evidence: marker/mechanism CTD PMID:19001277 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487
JBrowse link
G Cartpt CART prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:20886038 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
JBrowse link
G Cckbr cholecystokinin B receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9922984 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
JBrowse link
G Ccser1 coiled-coil serine-rich protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr 4:90,153,873...91,391,441
Ensembl chr 4:90,292,780...91,388,786
JBrowse link
G Cdk5 cyclin-dependent kinase 5 ISO RGD PMID:11268215 RGD:734739 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Ces1d carboxylesterase 1D ISO CTD Direct Evidence: therapeutic CTD PMID:12679808 PMID:12773168 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Ces2h carboxylesterase 2H ISO CTD Direct Evidence: therapeutic CTD PMID:19710369 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cfl1 cofilin 1 IEP protein:altered expression:striatum (rat) RGD PMID:27018876 RGD:11568696 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:13130510 NCBI chr 3:99,284,846...99,337,252
Ensembl chr 3:99,284,846...99,337,252
JBrowse link
G Cnr1 cannabinoid receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16314880 PMID:17596442 PMID:19052543 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Comt catechol-O-methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:18704099 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11717377 PMID:16359811 PMID:18596687 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Crh corticotropin releasing hormone IEP
ISO
mRNA:decreased expression:hypothalamus (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:7796157 PMID:10516337 PMID:11797056 PMID:18596687 PMID:19349312 More... RGD:5508177 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
JBrowse link
G Crhbp corticotropin releasing hormone binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:17437087 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IEP
ISO
mRNA:increased expression:anterior pituitary (rat)
CTD Direct Evidence: marker/mechanism
CTD
RGD
PMID:19339610 PMID:12576179 RGD:5508175 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481
JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17437087 NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18438686 NCBI chr20:8,692,939...8,946,780
Ensembl chr20:8,692,963...8,946,772
JBrowse link
G Drd1 dopamine receptor D1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15295029 PMID:16014726 PMID:16541082 PMID:20456009 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Drd2 dopamine receptor D2 IDA
ISO
protein:increased activity:caudate putamen (rat)
CTD Direct Evidence: marker/mechanism|therapeutic
CTD
RGD
PMID:10900248 PMID:11751029 PMID:11923462 PMID:15010698 PMID:15042275 More... RGD:2311586 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:10523822 PMID:15100700 PMID:17332411 PMID:18566292 PMID:20494958 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Egr1 early growth response 1 treatment IEP
ISO
CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD
PMID:16157275 PMID:16738229 PMID:18311559 PMID:25309368 PMID:21309948 RGD:10395309, RGD:10400880 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:20056891 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Esr2 estrogen receptor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17133264 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19014962 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:17276011 PMID:18311559 PMID:19533625 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:12657709 PMID:17898221 PMID:18539927 PMID:19331462 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994
JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19833324 PMID:20133874 NCBI chr14:37,097,251...37,230,030
Ensembl chr14:37,097,279...37,228,944
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gad1 glutamate decarboxylase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
JBrowse link
G Gad2 glutamate decarboxylase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155
JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17205118 NCBI chr 4:57,030,817...57,042,682
Ensembl chr 4:57,032,314...57,042,663
JBrowse link
G Gdnf glial cell derived neurotrophic factor ISO CTD Direct Evidence: therapeutic CTD PMID:14622243 PMID:15899247 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: marker/mechanism CTD PMID:17407494 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
JBrowse link
G Gphn gephyrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22253714 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
JBrowse link
G Gpsm1 G-protein signaling modulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15091342 NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:14684464 PMID:15764012 PMID:16495937 PMID:18430032 PMID:18486119 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18945913 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16014726 PMID:20149346 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO protein:decreased expression:prefrontal cortex (human) RGD PMID:23727505 RGD:13792719 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 ISO protein:decreased expression:prefrontal cortex (human) RGD PMID:23727505 RGD:13792719 NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 ISO protein:decreased expression:prefrontal cortex (human) RGD PMID:23727505 RGD:13792719 NCBI chr 1:260,028,269...260,223,699
Ensembl chr 1:260,028,242...260,218,701
JBrowse link
G Grm2 glutamate metabotropic receptor 2 IMP knockout compared to wild type RGD PMID:28700935 RGD:38501064 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
JBrowse link
G Grm2em1 glutamate metabotropic receptor 2; endonuclease induced mutant 1 IMP KO compared to wild-type rats RGD PMID:28700935 RGD:38501064
G Grm5 glutamate metabotropic receptor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20826661 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
JBrowse link
G Hcrt hypocretin neuropeptide precursor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16357203 NCBI chr10:85,689,979...85,691,214
Ensembl chr10:85,689,465...85,691,210
JBrowse link
G Hcrtr1 hypocretin receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16357203 PMID:19591850 PMID:19741128 NCBI chr 5:142,477,214...142,486,674
Ensembl chr 5:142,477,214...142,486,674
JBrowse link
G Hdac4 histone deacetylase 4 ISO CTD Direct Evidence: therapeutic CTD PMID:17988634 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hdac5 histone deacetylase 5 ISO CTD Direct Evidence: therapeutic CTD PMID:17988634 NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
JBrowse link
G Homer1 homer scaffold protein 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:16160706 PMID:16314758 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Homer2 homer scaffold protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15545022 NCBI chr 1:135,558,977...135,659,780
Ensembl chr 1:135,567,414...135,659,772
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:11853856 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9603521 PMID:17509084 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Cocaine-Related Disorders
CTD
ClinVar
PMID:9635956 PMID:11259563 PMID:12476319 PMID:15364038 PMID:16300424 More... NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Htr3b 5-hydroxytryptamine receptor 3B susceptibility ISO DNA:SNP:cds:rs1176744(human) RGD PMID:20838391 RGD:6480660 NCBI chr 8:49,279,291...49,308,444
Ensembl chr 8:49,279,173...49,308,444
JBrowse link
G