|
G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr15:101,948,387...102,182,912
|
|
G |
Ablim1 |
actin-binding LIM protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:266,088,868...266,377,169
|
|
G |
Adarb2 |
adenosine deaminase RNA specific B2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr17:61,750,437...62,300,984
|
|
G |
Aff3 |
ALF transcription elongation factor 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 9:40,399,099...40,856,716
|
|
G |
Agbl4 |
AGBL carboxypeptidase 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 5:130,483,551...131,762,906
|
|
G |
Akap7 |
A-kinase anchoring protein 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:21,906,503...22,168,663
|
|
G |
Ano4 |
anoctamin 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 7:23,329,015...23,738,423
|
|
G |
Appl2 |
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 7:20,135,248...20,184,757
|
|
G |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr13:76,786,580...76,807,096
|
|
G |
Bcar3 |
BCAR3 adaptor protein, NSP family member |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 2:210,525,260...210,638,674
|
|
G |
Bpifa2 |
BPI fold containing family A, member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 3:142,493,379...142,501,343
|
|
G |
C18h5orf63 |
similar to human chromosome 5 open reading frame 63 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr18:50,424,079...50,442,172
|
|
G |
C1h19orf18 |
similar to human chromosome 19 open reading frame 18 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:73,022,324...73,049,934
|
|
G |
Cadps2 |
calcium dependent secretion activator 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 4:52,746,054...53,275,252
|
|
G |
Ccdc91 |
coiled-coil domain containing 91 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 4:180,402,327...180,574,364
|
|
G |
Cd274 |
CD274 molecule |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:236,526,215...236,549,956
|
|
G |
Cdcp1 |
CUB domain containing protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 8:122,828,685...122,865,345
|
|
G |
Cdh13 |
cadherin 13 |
|
ISO IMP |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:20098672 PMID:28387990 |
RGD:13503340 |
NCBI chr19:46,349,562...47,387,462
|
|
G |
Cdh13em1Mcwi |
cadherin 13; zinc finger nuclease induced mutant 1, Medical College of Wisconsin |
|
IMP |
knock-out compared to wild-type rats |
RGD |
PMID:28387990 |
RGD:13503340 |
|
|
G |
Cers6 |
ceramide synthase 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 3:53,630,637...53,879,692
|
|
G |
Cftr |
CF transmembrane conductance regulator |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 4:47,422,084...47,694,646
|
|
G |
Chchd3 |
coiled-coil-helix-coiled-coil-helix domain containing 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 4:61,360,352...61,616,850
|
|
G |
Chd1l |
chromodomain helicase DNA binding protein 1-like |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 2:187,819,869...187,906,359
|
|
G |
Chrm2 |
cholinergic receptor, muscarinic 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20393457 |
|
NCBI chr 4:65,981,136...66,116,128
|
|
G |
Chrna5 |
cholinergic receptor nicotinic alpha 5 subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20438829 |
|
NCBI chr 8:55,369,794...55,398,526
|
|
G |
Cnr1 |
cannabinoid receptor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:9888857 PMID:18690112 PMID:21513772 |
|
NCBI chr 5:53,204,867...53,230,396
|
|
G |
Colec12 |
collectin sub-family member 12 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr18:732,950...920,620
|
|
G |
Csmd1 |
CUB and Sushi multiple domains 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr16:72,218,189...73,818,380
|
|
G |
Csmd3 |
CUB and Sushi multiple domains 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 7:78,747,322...80,066,466
|
|
G |
Csrnp3 |
cysteine and serine rich nuclear protein 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 3:70,906,587...71,102,596
|
|
G |
Csrp3 |
cysteine and glycine rich protein 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:98,528,067...98,546,647
|
|
G |
Ctnna3 |
catenin alpha 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr20:23,614,469...25,200,026
|
|
G |
Cxcl14 |
C-X-C motif chemokine ligand 14 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr17:8,323,150...8,331,176
|
|
G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17089107 |
|
NCBI chr 7:115,762,662...115,771,832
|
|
G |
Ddx1 |
DEAD-box helicase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 6:35,996,469...36,027,340
|
|
G |
Disc1 |
DISC1 scaffold protein |
severity |
ISO |
protein:altered expression:orbitofrontal cortex |
RGD |
PMID:15657124 |
RGD:5509834 |
NCBI chr19:53,014,201...53,223,617
|
|
G |
Dnah8 |
dynein, axonemal, heavy chain 8 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr20:8,692,939...8,946,780
|
|
G |
Dock1 |
dedicator of cyto-kinesis 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:189,467,143...189,983,777
|
|
G |
Drd2 |
dopamine receptor D2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16901644 |
|
NCBI chr 8:58,605,403...58,669,339
|
|
G |
Dscam |
DS cell adhesion molecule |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr11:35,921,924...36,507,100
|
|
G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr11:79,241,927...79,275,173
|
|
G |
Eipr1 |
EARP complex and GARP complex interacting protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 6:45,388,451...45,502,089
|
|
G |
Etv6 |
ETS variant transcription factor 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 4:166,849,031...167,085,211
|
|
G |
Faah |
fatty acid amide hydrolase |
susceptibility |
ISO |
ClinVar Annotator: match by term: Polysubstance abuse, susceptibility to CTD Direct Evidence: marker/mechanism DNA:missense mutation:cds:p.P129T (human) |
ClinVar OMIM CTD RGD |
PMID:12060782 PMID:15254019 PMID:16972078 PMID:19103437 PMID:23556448 PMID:25741868 PMID:16972078 PMID:12060782 More...
|
RGD:1625741, RGD:1300311 |
NCBI chr 5:134,716,545...134,735,396
|
|
G |
Fam184a |
family with sequence similarity 184, member A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr20:32,934,424...33,056,626
|
|
G |
Fam184b |
family with sequence similarity 184, member B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr14:65,475,489...65,591,388
|
|
G |
Farp1 |
FERM, ARH/RhoGEF and pleckstrin domain protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr15:98,124,304...98,363,299
|
|
G |
Faslg |
Fas ligand |
|
IDA |
|
RGD |
PMID:15644446 |
RGD:1358616 |
NCBI chr13:76,680,885...76,706,042
|
|
G |
Fhit |
fragile histidine triad diadenosine triphosphatase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr15:16,365,401...17,872,901
|
|
G |
Fhod3 |
formin homology 2 domain containing 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr18:15,993,079...16,425,796
|
|
G |
Fkbp15 |
FKBP prolyl isomerase family member 15 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 5:75,750,786...75,815,038
|
|
G |
Frmd4a |
FERM domain containing 4A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr17:73,667,787...74,258,487
|
|
G |
Gba3 |
glucosylceramidase beta 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr14:60,574,974...60,721,411
|
|
G |
Gria4 |
glutamate ionotropic receptor AMPA type subunit 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 8:1,562,118...2,035,035
|
|
G |
Grik2 |
glutamate ionotropic receptor kainate type subunit 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr20:53,717,564...54,415,283
|
|
G |
Grm5 |
glutamate metabotropic receptor 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:141,310,069...141,884,980
|
|
G |
Grm7 |
glutamate metabotropic receptor 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 4:143,730,862...144,613,230
|
|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
treatment |
IMP |
|
RGD |
PMID:30188517 |
RGD:13792724 |
NCBI chr11:76,004,502...76,154,665
|
|
G |
Hspa12a |
heat shock protein family A (Hsp70) member 12A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:257,935,642...258,096,602
|
|
G |
Htr2c |
5-hydroxytryptamine receptor 2C |
|
IMP |
|
RGD |
PMID:16474401 |
RGD:2292548 |
NCBI chr X:115,453,190...115,682,325
|
|
G |
Hycc1 |
hyccin PI4KA lipid kinase complex subunit 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 4:11,132,224...11,239,120
|
|
G |
Insr |
insulin receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr12:5,991,135...6,129,275
|
|
G |
Klf12 |
KLF transcription factor 12 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr15:83,037,548...83,469,998
|
|
G |
Ldlrad3 |
low density lipoprotein receptor class A domain containing 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 3:88,239,529...88,481,340
|
|
G |
Limch1 |
LIM and calponin homology domains 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr14:41,466,433...41,779,477
|
|
G |
Lrmda |
leucine rich melanocyte differentiation associated |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr15:1,275,139...2,334,153
|
|
G |
Macrod2 |
mono-ADP ribosylhydrolase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 3:127,720,066...129,737,511
|
|
G |
Mknk1 |
MAPK interacting serine/threonine kinase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 5:134,554,881...134,594,392
|
|
G |
Mpc1 |
mitochondrial pyruvate carrier 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:54,985,305...54,996,979
|
|
G |
Mpp7 |
MAGUK p55 scaffold protein 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr17:55,439,939...55,706,810
|
|
G |
Msra |
methionine sulfoxide reductase A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr15:38,363,459...38,677,406
|
|
G |
Myo5c |
myosin VC |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 8:84,870,031...84,946,996
|
|
G |
Myo6 |
myosin VI |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 8:81,087,157...81,242,022
|
|
G |
Nme7 |
NME/NM23 family member 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr13:79,190,462...79,319,890
|
|
G |
Npy |
neuropeptide Y |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19063928 |
|
NCBI chr 4:80,212,111...80,219,310
|
|
G |
Nrcam |
neuronal cell adhesion molecule |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16123759 |
|
NCBI chr 6:61,402,813...61,698,536
|
|
G |
Nrxn3 |
neurexin 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 6:107,641,760...109,272,849
|
|
G |
Oprd1 |
opioid receptor, delta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17622222 PMID:20098672 |
|
NCBI chr 5:149,590,244...149,624,999
|
|
G |
Oprm1 |
opioid receptor, mu 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27192616 |
|
NCBI chr 1:45,565,371...45,818,722
|
|
G |
Or51e1 |
olfactory receptor family 51 subfamily E member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:157,142,232...157,151,114
|
|
G |
Pacs1 |
phosphofurin acidic cluster sorting protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:202,437,503...202,569,473
|
|
G |
Parva |
parvin, alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:166,547,142...166,704,958
|
|
G |
Patj |
PATJ, crumbs cell polarity complex component |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 5:113,061,985...113,364,807
|
|
G |
Pbx1 |
PBX homeobox 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr13:80,278,766...80,588,563
|
|
G |
Pcdh15 |
protocadherin related 15 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr20:13,996,383...15,495,206
|
|
G |
Pde1c |
phosphodiesterase 1C |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 4:85,300,858...85,777,948
|
|
G |
Piwil1 |
piwi-like RNA-mediated gene silencing 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr12:27,949,743...27,970,645
|
|
G |
Pla2r1 |
phospholipase A2 receptor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 3:44,883,943...45,013,793
|
|
G |
Pmaip1 |
phorbol-12-myristate-13-acetate-induced protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr18:62,255,970...62,262,384
|
|
G |
Polr1d |
RNA polymerase I and III subunit D |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr12:7,970,592...8,004,157
|
|
G |
Prkce |
protein kinase C, epsilon |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 6:13,718,050...14,204,931
|
|
G |
Prkch |
protein kinase C, eta |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 6:98,027,830...98,226,486
|
|
G |
Prpf4 |
pre-mRNA splicing tri-snRNP complex factor PRPF4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 5:75,859,934...75,873,924
|
|
G |
Pten |
phosphatase and tensin homolog |
|
IMP |
|
RGD |
PMID:16474401 |
RGD:2292548 |
NCBI chr 1:240,043,707...240,110,330
|
|
G |
Qsox1 |
quiescin sulfhydryl oxidase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr13:67,949,780...67,987,434
|
|
G |
Rad51b |
RAD51 paralog B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 6:98,096,525...98,640,988
|
|
G |
Rhbdd3 |
rhomboid domain containing 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr14:79,994,111...80,000,294
|
|
G |
Rtl6 |
retrotransposon Gag like 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 7:115,684,812...115,689,897
|
|
G |
Samd4a |
sterile alpha motif domain containing 4A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr15:22,616,200...22,831,872
|
|
G |
Sema6d |
semaphorin 6D |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 3:131,801,680...132,394,578
|
|
G |
Slc10a2 |
solute carrier family 10 member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr16:91,088,089...91,111,025
|
|
G |
Slc18a2 |
solute carrier family 18 member A2 |
|
IEP |
protein:increased cysteine nitrosylation:striatum, vesicle (rat) |
RGD |
PMID:17683483 |
RGD:5131179 |
NCBI chr 1:258,413,748...258,449,143
|
|
G |
Slc22a3 |
solute carrier family 22 member 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17010131 |
|
NCBI chr 1:50,783,218...50,872,358
|
|
G |
Slc2a13 |
solute carrier family 2 member 13 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 7:122,399,329...122,726,605
|
|
G |
Slc45a2 |
solute carrier family 45, member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 2:59,963,599...59,996,408
|
|
G |
Slc6a4 |
solute carrier family 6 member 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19272758 |
|
NCBI chr10:62,322,688...62,357,060
|
|
G |
Slk |
STE20-like kinase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:256,415,013...256,470,942
|
|
G |
Spmip5 |
sperm microtubule inner protein 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:257,926,555...257,934,873
|
|
G |
Syne1 |
spectrin repeat containing nuclear envelope protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:41,512,146...41,983,382
|
|
G |
Tenm2 |
teneurin transmembrane protein 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr10:20,984,710...22,121,001
|
|
G |
Thsd4 |
thrombospondin type 1 domain containing 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 8:60,384,636...60,984,419
|
|
G |
Tiam2 |
TIAM Rac1 associated GEF 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:43,918,179...44,119,499
|
|
G |
Tmprss7 |
transmembrane serine protease 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr11:55,127,992...55,166,597
|
|
G |
Ttc21b |
tetratricopeptide repeat domain 21B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 3:71,269,425...71,343,936
|
|
G |
Wdr11 |
WD repeat domain 11 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:184,165,260...184,210,834
|
|
G |
Xkr4 |
XK related 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 5:15,896,818...16,297,733
|
|
G |
Xpo6 |
exportin 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:180,672,114...180,761,543
|
|
G |
Xylt1 |
xylosyltransferase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:171,643,925...171,929,774
|
|
G |
Zfp366 |
zinc finger protein 366 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 2:30,578,552...30,640,546
|
|
G |
Zfp385d |
zinc finger protein 385D |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr15:5,040,182...5,849,975
|
|
G |
Zfp606 |
zinc finger protein 606 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 1:72,981,920...73,022,423
|
|
G |
Zfp804a |
zinc finger protein 804A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20098672 |
|
NCBI chr 3:67,033,481...67,267,769
|
|
|
G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
|
ISO |
ClinVar Annotator: match by term: ALDH2-related condition | ClinVar Annotator: match by term: Alcohol sensitivity, acute | ClinVar Annotator: match by term: Susceptibility to hangover |
ClinVar |
PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 PMID:8903321 PMID:10627091 PMID:10780266 PMID:15654505 PMID:15902904 PMID:16046871 PMID:16440063 PMID:16679777 PMID:17885622 PMID:18056758 PMID:20010786 PMID:22992668 PMID:25741868 PMID:28492532 PMID:33355142 More...
|
|
NCBI chr12:40,610,244...40,643,220
|
|
|
G |
Adcyap1 |
adenylate cyclase activating polypeptide 1 |
susceptibility |
ISO |
DNA:SNP:: (rs2856966) (human) |
RGD |
PMID:20554694 |
RGD:401976551 |
NCBI chr 9:113,102,632...113,122,500
|
|
G |
Adh1c |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
|
ISO |
associated with other drug dependencies; DNA:SNPs:CDS: (rs904096) ClinVar Annotator: match by term: Alcohol dependence |
OMIM ClinVar RGD |
PMID:3397059 PMID:3758060 PMID:10090900 PMID:15863807 PMID:17718394 PMID:17923853 PMID:25741868 PMID:27151647 More...
|
RGD:405650603 |
NCBI chr 2:226,797,303...226,808,892
|
|
G |
Adh4 |
alcohol dehydrogenase 4 (class II), pi polypeptide |
|
ISO |
|
RGD |
PMID:20077761 |
RGD:401827938 |
NCBI chr 2:226,948,717...226,966,747
|
|
G |
Adra2a |
adrenoceptor alpha 2A |
susceptibility |
ISO IEP |
DNA:SNP:promoter: C-1291G (rs1800544) (human) associated with stress-related disorder; mRNA:decreased expression:hypothalamus (rat) |
RGD |
PMID:21070505 PMID:26121187 |
RGD:401976462, RGD:401976544 |
NCBI chr 1:263,066,780...263,069,580
|
|
G |
Ago1 |
argonaute RISC component 1 |
susceptibility |
ISO |
DNA:SNP:intron:A>G(rs595961)(human) |
RGD |
PMID:25495208 |
RGD:401900681 |
NCBI chr 5:138,722,111...138,757,118
|
|
G |
Ago2 |
argonaute RISC catalytic component 2 |
susceptibility |
ISO |
DNA:SNP:promoter:A>C(rs4961280)(human) |
RGD |
PMID:25495208 |
RGD:401900681 |
NCBI chr 7:106,907,209...106,994,124
|
|
G |
Ahr |
aryl hydrocarbon receptor |
|
ISO |
mRNA:decreased expression:duodenum: |
RGD |
PMID:34454169 |
RGD:405866377 |
NCBI chr 6:57,961,423...57,998,901
|
|
G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
|
ISO |
ClinVar Annotator: match by term: Alcohol dependence DNA:SNP: :1510G>A (human) |
ClinVar RGD |
PMID:2987944 PMID:4065146 PMID:6650498 PMID:7180842 PMID:7593603 PMID:8903321 PMID:10627091 PMID:10780266 PMID:15654505 PMID:15902904 PMID:16046871 PMID:16440063 PMID:16679777 PMID:17885622 PMID:18056758 PMID:20010786 PMID:22992668 PMID:33355142 PMID:20077761 PMID:16679777 More...
|
RGD:401827938, RGD:401827936 |
NCBI chr12:40,610,244...40,643,220
|
|
G |
Angpt1 |
angiopoietin 1 |
|
ISO |
associated with other drug dependencies; DNA:SNPs:CDS:intron (rs10090742) |
RGD |
PMID:27151647 |
RGD:405650603 |
NCBI chr 7:75,415,959...75,668,696
|
|
G |
Ankk1 |
ankyrin repeat and kinase domain containing 1 |
susceptibility |
ISO |
DNA:polymorphism:exon: DNA:SNP,haplotype:exon:rs1800497(human) |
RGD |
PMID:28574012 PMID:23443985 |
RGD:401959222, RGD:401959307 |
NCBI chr 8:58,676,327...58,685,012
|
|
G |
Ar |
androgen receptor |
severity |
ISO |
DNA:repeats:N-terminal DNA:repeat, haplotype:exon |
RGD |
PMID:19231085 PMID:24271034 |
RGD:407424612, RGD:407550222 |
NCBI chr X:63,104,771...63,273,934
|
|
G |
Arrb2 |
arrestin, beta 2 |
|
IEP |
mRNA:decreased expression:nucleus accumbens |
RGD |
PMID:34919270 |
RGD:401938593 |
NCBI chr10:55,645,539...55,653,485
|
|
G |
Avp |
arginine vasopressin |
|
ISO IEP |
protein:decreased expression:cerebrospinal fluid protein:decreased expression:blood plasma mRNA:increased expression:paraventricular nucleus of hypothalamus |
RGD |
PMID:7106059 PMID:15608610 PMID:9622448 |
RGD:408426006, RGD:596933105, RGD:529435544 |
NCBI chr 3:138,246,544...138,248,522
|
|
G |
Avpr1b |
arginine vasopressin receptor 1B |
|
IEP |
|
RGD |
PMID:21309953 |
RGD:14700679 |
NCBI chr13:43,046,531...43,059,046
|
|
G |
Bdnf |
brain-derived neurotrophic factor |
treatment sexual_dimorphism |
IDA ISO IEP |
protein:altered expression:hippocampus |
RGD |
PMID:34453945 PMID:37303582 PMID:32579730 |
RGD:401959604, RGD:596936394, RGD:401959610 |
NCBI chr 3:116,619,633...116,670,212
|
|
G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
susceptibility |
ISO |
DNA:SNP::(rs6486120) (human) |
RGD |
PMID:20554694 |
RGD:401976551 |
NCBI chr 1:176,766,222...176,864,741
|
|
G |
Bmal2 |
basic helix-loop-helix ARNT like 2 |
susceptibility |
ISO |
DNA:SNPs, haplotype:: (rs7958822,rs4964057) (human) |
RGD |
PMID:20554694 |
RGD:401976551 |
NCBI chr 4:179,699,432...179,747,710
|
|
G |
Bptf |
bromodomain PHD finger transcription factor |
|
ISO |
associated with other drug dependencies; DNA:SNPs:CDS:intron (rs11870068) |
RGD |
PMID:27151647 |
RGD:405650603 |
NCBI chr10:92,480,007...92,582,485
|
|
G |
Cacna1c |
calcium voltage-gated channel subunit alpha1 C |
|
IEP |
mRNA, protein:increased expression:amygdala, hippocampus (rat) protein:increased expression:inferior colliculus (human) |
RGD |
PMID:27905406 PMID:25556199 |
RGD:152985537, RGD:152985539 |
NCBI chr 4:151,764,138...152,379,454
|
|
G |
Cck |
cholecystokinin |
susceptibility |
ISO |
DNA:SNP:promoter: -45C>T (human) |
RGD |
PMID:9622381 |
RGD:407419865 |
NCBI chr 8:121,153,499...121,160,194
|
|
G |
Cdk20 |
cyclin-dependent kinase 20 |
susceptibility |
ISO |
DNA:SNP:: (rs560019) (human) |
RGD |
PMID:18438686 |
RGD:401851917 |
NCBI chr17:706,863...717,828
|
|
G |
Chat |
choline O-acetyltransferase |
|
ISO |
protein:decreased expression:hippocampus,septum,striatum |
RGD |
PMID:8436061 |
RGD:401976285 |
NCBI chr16:7,657,362...7,717,093
|
|
G |
Chrna3 |
cholinergic receptor nicotinic alpha 3 subunit |
susceptibility |
ISO |
DNA:missense:exons:p.R37H,p.E363D(human) |
RGD |
PMID:24057674 |
RGD:405849397 |
NCBI chr 8:55,401,668...55,415,165
|
|
G |
Chrnb3 |
cholinergic receptor nicotinic beta 3 subunit |
susceptibility |
ISO |
DNA:missense:exons:multiple(human) |
RGD |
PMID:24057674 |
RGD:405849397 |
NCBI chr16:64,713,438...64,751,360
|
|
G |
Clock |
clock circadian regulator |
exacerbates |
ISO |
|
RGD |
PMID:23722243 |
RGD:401976471 |
NCBI chr14:32,262,747...32,346,872
|
|
G |
Comt |
catechol-O-methyltransferase |
susceptibility sexual_dimorphism onset disease_progression |
ISO |
associated with Alzheimer's disease; DNA:SNP:cd: P.V158M G>A (rs4680) (human) DNA:SNPs,haplotypes:: (rs165774,rs4680) (human) DNA:SNPs,haplotype:exon 4: p.V158M (rs4680) (human) DNA:SNP:cd: p.V158M (rs4680) (human) DNA:SNP:cd: p.V158M (human) associated with major depressive disorder; DNA:SNP:cd: p.V158M (human) DNA:polymorphism:exon 4: p.V158M (rs4680)(human) associated with schizophrenia; DNA:promoter:Hypermethylation associated with Trauma and Stressor Related Disorders ; DNA:polymorphism:exon: p.V158M (human) |
RGD |
PMID:25491588 PMID:22208661 PMID:16499480 PMID:24390676 PMID:16648777 PMID:20860878 PMID:25035107 PMID:16984965 PMID:20517217 PMID:11244495 PMID:31150143 PMID:10698363 More...
|
RGD:11073926, RGD:401959747, RGD:401959300, RGD:401940156, RGD:401940155, RGD:401940149, RGD:401940148, RGD:401940146, RGD:401940133, RGD:401940131, RGD:401940120, RGD:401940118 |
NCBI chr11:96,072,371...96,091,956
|
|
G |
Cpe |
carboxypeptidase E |
|
ISO |
associated with other drug dependencies; DNA:SNPs:CDS:intron (rs10517844) DNA:SNP:CDS: (rs13706874) (human) |
RGD |
PMID:27151647 PMID:20201924 |
RGD:405650603, RGD:405650609 |
NCBI chr16:25,030,276...25,142,231
|
|
G |
Creb1 |
cAMP responsive element binding protein 1 |
treatment |
ISO IEP IDA |
DNA:SNP:exon:rs35349697 protein:increased phosphorylation:prefrontal cortex (rat) mRNA,protein:decreased expression:hippocampus |
RGD |
PMID:24704376 PMID:19324071 PMID:21951632 PMID:32579730 PMID:34453945 PMID:37031608 More...
|
RGD:401938627, RGD:401901600, RGD:401959743, RGD:401959610, RGD:401959604, RGD:401959603 |
NCBI chr 9:73,397,333...73,466,339
|
|
G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
|
ISO |
protein:increased expression:brain |
RGD |
PMID:12354285 |
RGD:401901262 |
NCBI chr 7:115,762,662...115,771,832
|
|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
|
IDA |
|
RGD |
PMID:9927612 |
RGD:405650696 |
NCBI chr 1:205,269,967...205,280,365
|
|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
IDA |
|
RGD |
PMID:9927612 |
RGD:405650696 |
NCBI chr12:14,321,771...14,343,886
|
|
G |
Cyp3a23-3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
|
IDA |
|
RGD |
PMID:9927612 |
RGD:405650696 |
NCBI chr12:14,369,950...14,398,803
|
|
G |
Dbi |
diazepam binding inhibitor |
susceptibility no_association |
ISO |
DNA:SNP:: +529A>T (rs8192503) (human) DNA:SNP:: +529A>T (human) DNA:SNP:: (rs2276596) (human) |
RGD |
PMID:18240651 PMID:21226341 PMID:24818357 |
RGD:408346758, RGD:408361841, RGD:408346759 |
NCBI chr13:33,794,231...33,802,632
|
|
G |
Dgcr8 |
DGCR8 microprocessor complex subunit |
susceptibility |
ISO |
DNA:SNP:3���-UTR:G>T(rs1640299)(human) |
RGD |
PMID:25495208 |
RGD:401900681 |
NCBI chr11:96,208,959...96,241,560
|
|
G |
Drd1 |
dopamine receptor D1 |
|
IMP |
|
RGD |
PMID:17360123 |
RGD:405100958 |
NCBI chr17:10,545,488...10,550,029
|
|
G |
Drd2 |
dopamine receptor D2 |
onset susceptibility |
ISO |
DNA:insertion, deletion:promoter: DNA:SNP: :rs1800498(human) |
RGD |
PMID:23238469 PMID:36825486 |
RGD:401959213, RGD:401959301 |
NCBI chr 8:58,605,403...58,669,339
|
|
G |
Drd4 |
dopamine receptor D4 |
no_association |
ISO |
DNA:repeats:exon: |
RGD |
PMID:9342196 |
RGD:401959738 |
NCBI chr 1:205,825,937...205,829,124
|
|
G |
Fkbp5 |
FKBP prolyl isomerase 5 |
susceptibility |
ISO IEP |
associated with stress-related disorder;DNA:SNP:: (rs1360780) (human) associated with stress-related disorder;mRNA:affects expression:ventral tegmental area,cingulate cortex, nucleus accumbens( rat) DNA:SNPs:intron,3'utr: (rs1360780, rs3800373) |
RGD |
PMID:27527158 PMID:27709495 PMID:27709495 PMID:27527158 |
RGD:401976484, RGD:401976487, RGD:401976487, RGD:401976484 |
NCBI chr20:6,458,931...6,577,227
|
|
G |
Fmn1 |
formin 1 |
|
ISO |
associated with other drug dependencies; DNA:SNPs:CDS: (rs3910705) |
RGD |
PMID:27151647 |
RGD:405650603 |
NCBI chr 3:100,101,103...100,485,652
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
treatment |
IDA IEP |
protein:increased expression:granular insular cortex, paraventricular nucleus of thalamus, prefrontal cortex |
RGD |
PMID:29926762 PMID:17723286 PMID:14574439 PMID:17360123 |
RGD:405100722, RGD:405295497, RGD:405101697, RGD:405100958 |
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
treatment |
IEP |
protein:increased expression:nucleus accumbens (rat) associated with Sleep Deprivation;protein:increased expression:brain |
RGD |
PMID:20626732 PMID:19324071 PMID:33662520 |
RGD:401851075, RGD:401901600, RGD:401900733 |
NCBI chr 1:88,082,324...88,089,506
|
|
G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
susceptibility severity |
ISO |
DNA:SNP:5'utr: -93A>G (rs45490695) (human) DNA:SNP:5'utr: T137346C (human) |
RGD |
PMID:18849153 PMID:14675807 |
RGD:408345238, RGD:408345249 |
NCBI chr20:44,322,635...44,514,498
|
|
G |
Gabbr1 |
gamma-aminobutyric acid type B receptor subunit 1 |
susceptibility treatment |
ISO IMP HEP |
DNA:SNP, haplotype:intron: C>G (rs29220) (human) DNA:SNP:Exon 11: T1974C (Human) mRNA:decreased expression:hippocampus (rat) DNA:SNP:intron: (rs29220) (human) DNA:SNP:intron: (rs29253) (human) |
RGD |
PMID:26727527 PMID:36095322 PMID:36095322 PMID:10412185 PMID:22253714 PMID:29968397 PMID:25191505 More...
|
RGD:11552767, RGD:401976442, RGD:401976442, RGD:401959601, RGD:401900163, RGD:401940102, RGD:401940100 |
NCBI chr20:1,469,779...1,499,352
|
|
G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
|
HEP |
mRNA:decreased expression:hippocampus (rat) |
RGD |
PMID:22253714 |
RGD:401900163 |
NCBI chr 5:60,947,517...61,288,104
|
|
G |
Gabra2 |
gamma-aminobutyric acid type A receptor subunit alpha 2 |
|
ISO |
ClinVar Annotator: match by term: Alcohol dependence |
ClinVar OMIM |
PMID:25741868 |
|
NCBI chr14:37,451,218...37,587,458
|
|
G |
Gabrb3 |
gamma-aminobutyric acid type A receptor subunit beta 3 |
susceptibility |
ISO |
DNA:SNPs: : |
RGD |
PMID:14745296 |
RGD:405866351 |
NCBI chr 1:117,602,772...117,838,230
|
|
G |
Gabrg2 |
gamma-aminobutyric acid type A receptor subunit gamma 2 |
|
ISO HEP |
DNA:SNPs, haplotype:introns:IVS9+99C>A, IVS10+3145A>G (rs211014, rs211013) (human) mRNA:decreased expression:hippocampus (human) mRNA:increased expression:hippocampus (rat) |
RGD |
PMID:15630072 PMID:22253714 PMID:22253714 |
RGD:402463959, RGD:401900163, RGD:401900163 |
NCBI chr10:26,876,926...26,965,523
|
|
G |
Gad1 |
glutamate decarboxylase 1 |
susceptibility onset |
ISO |
DNA:SNPs, haplotype:5'UTR,IVS:Rs3749034,Rs2270335,Rs10439259(human) DNA:SNPs: haplotype:multiple:rs1978340(human) |
RGD |
PMID:17067345 PMID:19111404 |
RGD:401900127, RGD:401900129 |
NCBI chr 3:75,777,260...75,818,099
|
|
G |
Gad2 |
glutamate decarboxylase 2 |
susceptibility |
ISO |
DNA:SNP::-243A>G (rs2236418) |
RGD |
PMID:17034009 |
RGD:401900120 |
NCBI chr17:89,671,718...89,734,246
|
|
G |
Gdnf |
glial cell derived neurotrophic factor |
treatment |
IMP IDA ISO |
protein:decreased expression:serum |
RGD |
PMID:15659598 PMID:19232578 PMID:20553781 PMID:24801661 |
RGD:405820207, RGD:405850246, RGD:405849399, RGD:405849388 |
NCBI chr 2:58,621,327...58,647,242
|
|
G |
Gemin4 |
gem (nuclear organelle) associated protein 4 |
susceptibility |
ISO |
DNA:SNP:Promoter:C>T(rs910924)(human) |
RGD |
PMID:25495208 |
RGD:401900681 |
NCBI chr10:61,062,420...61,073,529
|
|
G |
Ggt1 |
gamma-glutamyltransferase 1 |
|
IEP |
protein:increased activity:plasma,liver,intestine: |
RGD |
PMID:6113606 |
RGD:14701046 |
NCBI chr20:13,074,695...13,104,095
|
|
G |
Gria1 |
glutamate ionotropic receptor AMPA type subunit 1 |
ameliorates |
ISO |
|
RGD |
PMID:33955100 |
RGD:405649731 |
NCBI chr10:41,710,540...42,030,105
|
|
G |
Grin2a |
glutamate ionotropic receptor NMDA type subunit 2A |
susceptibility ameliorates |
ISO |
DNA:repeats:promoter:(GT)n DNA:mutation:cds:A825W(mouse) |
RGD |
PMID:21507155 PMID:33052417 PMID:29953905 |
RGD:401938633, RGD:401938638, RGD:401938635 |
NCBI chr10:6,136,458...6,560,003
|
|
G |
Grm8 |
glutamate metabotropic receptor 8 |
susceptibility |
ISO |
DNA:SNPs:intron 1: (rs886003, rs17862325) (human) |
RGD |
PMID:25978827 |
RGD:11070870 |
NCBI chr 4:55,805,762...56,731,690
|
|
G |
Gstt1 |
glutathione S-transferase theta 1 |
|
ISO |
|
RGD |
PMID:29582627 |
RGD:14700988 |
NCBI chr20:12,856,068...12,873,020
|
|
G |
Hmgb1 |
high mobility group box 1 |
|
ISO |
protein:increased expression:orbitofrontal cortex |
RGD |
PMID:23206318 |
RGD:7175526 |
NCBI chr12:11,009,236...11,015,941
|
|
G |
Htr1a |
5-hydroxytryptamine receptor 1A |
|
ISO |
mRNA:increased expression:Brodmann (1909) area 9 associated with nicotine dependence;DNA:SNPs:enhancer:multiple DNA:SNP: :140G>C |
RGD |
PMID:22176604 PMID:23216389 PMID:19060480 |
RGD:401900608, RGD:405849412, RGD:401900293 |
NCBI chr 2:38,427,169...38,431,733
|
|
G |
Htr1b |
5-hydroxytryptamine receptor 1B |
susceptibility onset sexual_dimorphism no_association |
ISO |
DNA:SNP:5'UTR:-161A>T (human) DNA:SNP: :861G>C (human) DNA:SNP: :861G>C(human) DNA:SNP,haplotype:promoter:161A>T (human) DNA:SNP:promoter:rs11568817 (human) |
RGD |
PMID:12022963 PMID:21906503 PMID:11104852 PMID:11827742 PMID:21172311 PMID:22005095 More...
|
RGD:405650693, RGD:405847406, RGD:405847401, RGD:405818273, RGD:405650698, RGD:405650694 |
NCBI chr 8:91,395,405...91,414,815
|
|
G |
Htr2a |
5-hydroxytryptamine receptor 2A |
disease_progression treatment no_association |
ISO IMP IEP |
DNA:SNP: :102T>C (rs6313) protein:decreased expression:agranular insular cortex, cingulate cortex, frontal cortex DNA:SNP:promoter:-1438G>A (rs6311) |
RGD |
PMID:23321485 PMID:8822536 PMID:15080502 PMID:19328219 PMID:19060480 PMID:21930285 More...
|
RGD:401900291, RGD:401900739, RGD:401900737, RGD:401900304, RGD:401900293, RGD:401900297 |
NCBI chr15:56,360,647...56,428,703
|
|
G |
Htr3a |
5-hydroxytryptamine receptor 3A |
exacerbates treatment susceptibility |
ISO IEP |
mRNA:increased expression:peripheral blood mononuclear cell (human) DNA:SNPs:enhancer, exon: (rs1150226, rs1176713) (human) DNA:SNPs, haplotype:multiple (human) mRNA:increased expression:prefrontal cortex (rat) DNA:SNP:exon 1: (rs33940208) (human) |
RGD |
PMID:27144979 PMID:23897038 PMID:24590108 PMID:25722691 PMID:23757001 |
RGD:404976874, RGD:405096433, RGD:404976878, RGD:404976876, RGD:404976875 |
NCBI chr 8:58,138,514...58,150,960
|
|
G |
Il1rn |
interleukin 1 receptor antagonist |
|
ISO |
protein:increased expression:blood |
RGD |
PMID:14634483 |
RGD:405878079 |
NCBI chr 3:27,509,836...27,525,738
|
|
G |
Kcnb2 |
potassium voltage-gated channel subfamily B member 2 |
|
ISO |
associated with other drug dependencies; DNA:SNPs:CDS:intron (rs2251898) |
RGD |
PMID:27151647 |
RGD:405650603 |
NCBI chr 5:3,567,012...4,028,564
|
|
G |
Lep |
leptin |
severity |
IDA ISO IEP |
DNA:hypermethylation:promoter DNA:hypomethylation:promoter protein:decreased expression:serum |
RGD |
PMID:29912265 PMID:30650427 PMID:19884906 PMID:29912265 |
RGD:21201248, RGD:407572512, RGD:407424613, RGD:21201248 |
NCBI chr 4:58,626,529...58,640,663
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
treatment |
IDA |
|
RGD |
PMID:34453945 |
RGD:401959604 |
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
treatment |
IDA |
|
RGD |
PMID:34453945 |
RGD:401959604 |
NCBI chr 1:190,797,189...190,803,411
|
|
G |
Mc4r |
melanocortin 4 receptor |
treatment |
IMP |
|
RGD |
PMID:24635847 |
RGD:407572518 |
NCBI chr18:62,689,798...62,691,685
|
|
G |
Ncam1 |
neural cell adhesion molecule 1 |
susceptibility |
ISO |
DNA:SNPs:exon: |
RGD |
PMID:17761687 |
RGD:405866369 |
NCBI chr 8:58,762,088...59,062,131
|
|
G |
Ngf |
nerve growth factor |
|
ISO IEP |
protein:increased expression:serum protein:decreased expression:sciatic nerve protein:decreased expression:plasma |
RGD |
PMID:17434673 PMID:8733743 PMID:16737466 |
RGD:401965399, RGD:401976493, RGD:401965409 |
NCBI chr 2:192,589,580...192,642,971
|
|
G |
Ngfr |
nerve growth factor receptor |
|
IEP |
protein:altered expression:brain,neuron |
RGD |
PMID:7609866 |
RGD:401976553 |
NCBI chr10:81,012,077...81,030,305
|
|
G |
Nkain2 |
sodium/potassium transporting ATPase interacting 2 |
susceptibility |
ISO |
DNA:SNP: :rs637547 (human) |
RGD |
PMID:21445666 |
RGD:596938167 |
NCBI chr 1:24,668,627...25,877,051
|
|
G |
Npy |
neuropeptide Y |
susceptibility |
ISO |
DNA:SNP:cd: p.L7P (rs16139) (human) |
RGD |
PMID:20554694 |
RGD:401976551 |
NCBI chr 4:80,212,111...80,219,310
|
|
G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
treatment |
IMP ISO |
|
RGD |
PMID:25886852 PMID:26121746 |
RGD:408345235, RGD:408345252 |
NCBI chr18:31,522,783...31,644,508
|
|
G |
Nr3c2 |
nuclear receptor subfamily 3, group C, member 2 |
|
IEP |
mRNA:altered expression:central amygdaloid nucleus (rat) |
RGD |
PMID:28461696 |
RGD:401960064 |
NCBI chr19:47,619,853...47,964,089
|
|
G |
Nrm |
nurim |
|
ISO |
associated with other drug dependencies; DNA:SNPs:CDS:intron (rs2269705) |
RGD |
PMID:27151647 |
RGD:405650603 |
NCBI chr20:2,888,321...2,892,804
|
|
G |
Nrxn3 |
neurexin 3 |
susceptibility |
ISO |
DNA:SNP,haplotype:Chr14:rs8019381, rs760288|rs8019381|2rs2293847 (human) |
RGD |
PMID:17804423 |
RGD:405096431 |
NCBI chr 6:107,641,760...109,272,849
|
|
G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
onset |
ISO |
DNA:SNPs: :rs993315, rs10780691 DNA:SNP: :rs1439047 |
RGD |
PMID:17200667 PMID:28512340 |
RGD:408395149, RGD:596933091 |
NCBI chr17:5,560,558...5,875,899
|
|
G |
Ntsr1 |
neurotensin receptor 1 |
susceptibility |
ISO |
DNA:SNPs,haplotype::rs6011914,rs2427422(human) |
RGD |
PMID:23743782 |
RGD:596948429 |
NCBI chr 3:187,983,778...188,033,934
|
|
G |
Nucb2 |
nucleobindin 2 |
|
IEP |
mRNA,protein:decreased expression:hippocampus |
RGD |
PMID:37031608 |
RGD:401959603 |
NCBI chr 1:170,750,830...170,787,356
|
|
G |
Oprd1 |
opioid receptor, delta 1 |
|
ISO |
DNA:SNP,haplotype:intron 1 (rs2298896|rs421300), multiple GCAAT (human) |
RGD |
PMID:17622222 |
RGD:401976552 |
NCBI chr 5:149,590,244...149,624,999
|
|
G |
Oprk1 |
opioid receptor, kappa 1 |
no_association |
ISO |
DNA:SNPs:intron:multiple DNA:SNP,haplotype:multiple (multiple GGCTTCT) (human) mRNA:increased expression:orbitofrontal cortex DNA:SNP: :rs6473797 (human) |
RGD |
PMID:16924269 PMID:17622222 PMID:21955155 PMID:24035285 |
RGD:401850571, RGD:401976552, RGD:401850584, RGD:401850579 |
NCBI chr 5:18,657,866...18,675,671
|
|
G |
Oprm1 |
opioid receptor, mu 1 |
no_association treatment sexual_dimorphism |
ISO |
DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human) DNA:SNP: :rs1799971 (human) |
RGD |
PMID:16679777 PMID:24035285 PMID:30748046 PMID:11424981 PMID:35992511 PMID:17374034 PMID:18250251 PMID:20077761 PMID:20077761 More...
|
RGD:401827936, RGD:401850579, RGD:401831038, RGD:401827953, RGD:401827952, RGD:401827944, RGD:11097488, RGD:401827938, RGD:401827938 |
NCBI chr 1:45,565,371...45,818,722
|
|
G |
Oxtr |
oxytocin receptor |
treatment susceptibility ameliorates |
ISO IMP |
associated with anxiety disorder; DNA:SNP:intron: (rs2254298) (human) rat gene in mouse model |
RGD |
PMID:28150062 PMID:37520225 PMID:25449413 PMID:27306084 |
RGD:597538533, RGD:597538604, RGD:597538598, RGD:597015745 |
NCBI chr 4:147,154,374...147,171,723
|
|
G |
Pde4b |
phosphodiesterase 4B |
susceptibility |
ISO |
DNA:SNP:: (rs1937443) (human) |
RGD |
PMID:18438686 |
RGD:401851917 |
NCBI chr 5:122,028,956...122,598,267
|
|
G |
Pdyn |
prodynorphin |
no_association disease_progression |
ISO |
DNA:SNP, hypermethylation:promoter:rs2235751 (human) mRNA, protein:increased expression:dorsolateral prefrontal cortex, orbitofrontal cortex DNA:SNP: :rs1997794 (human) DNA:SNP, hypermethylation:dorsolateral prefrontal cortex:rs2281285 (human) DNA:SNP: :rs2281285 (human) DNA:SNPs: :multiple DNA:SNPs, haplotypes:multiple |
RGD |
PMID:28336495 PMID:21955155 PMID:24035285 PMID:21521424 PMID:26502829 PMID:16924269 PMID:24223163 PMID:23101464 More...
|
RGD:401850551, RGD:401850584, RGD:401850579, RGD:401850575, RGD:11535796, RGD:401850571, RGD:401850565, RGD:401850560 |
NCBI chr 3:137,354,161...137,366,503
|
|
G |
Per2 |
period circadian regulator 2 |
|
ISO |
DNA, mRNA:hypermethylation, decreased expression:blood DNA:hypermethylation:blood, promoter |
RGD |
PMID:30597578 PMID:31329297 |
RGD:405878075, RGD:405878078 |
NCBI chr 9:99,454,828...99,497,069
|
|
G |
Pknox2 |
PBX/knotted 1 homeobox 2 |
|
ISO |
associated with other drug dependencies; DNA:SNPs:CDS:intron (rs750338) |
RGD |
PMID:27151647 |
RGD:405650603 |
NCBI chr 8:36,600,633...36,863,131
|
|
G |
Pomc |
proopiomelanocortin |
no_association |
ISO IDA IEP |
DNA:SNP: :rs934778 (human) DNA:hypermethylation:promoter:blood mRNA:decreased expression:hypothalamus mRNA:increased expression:pituitary gland mRNA:increased expression:blood, lymphocyte DNA:hypermethylation:blood, promoter DNA, mRNA:hypermethylation, decreased expression:blood mRNA:increased expression:blood, lymphocytes |
RGD |
PMID:24035285 PMID:24635847 PMID:20191296 PMID:11981131 PMID:7662043 PMID:14634483 PMID:31329297 PMID:30597578 PMID:9426836 More...
|
RGD:401850579, RGD:407572518, RGD:407431644, RGD:407424597, RGD:406179436, RGD:405878079, RGD:405878078, RGD:405878075, RGD:405878074 |
NCBI chr 6:32,659,137...32,665,175
|
|
G |
Prl |
prolactin |
treatment |
ISO |
|
RGD |
PMID:11418230 |
RGD:401959332 |
NCBI chr17:38,287,355...38,298,234
|
|
G |
Rgs6 |
regulator of G-protein signaling 6 |
|
ISO |
associated with other drug dependencies; DNA:SNPs:CDS: (rs11621871) |
RGD |
PMID:27151647 |
RGD:405650603 |
NCBI chr 6:102,264,451...102,796,311
|
|
G |
Slc29a1 |
solute carrier family 29 member 1 |
|
ISS |
OMIM:103780 |
MouseDO |
|
|
NCBI chr 9:22,897,099...22,911,640
|
|
G |
Slc6a1 |
solute carrier family 6 member 1 |
susceptibility |
ISO |
DNA:insertion:promoter:: (human) |
RGD |
PMID:26727527 |
RGD:11552767 |
NCBI chr 4:147,448,961...147,482,295
|
|
G |
Slc6a2 |
solute carrier family 6 member 2 |
susceptibility |
ISO |
DNA:SNPs,haplotypes:intron: (rs36020,rs36029) (human) |
RGD |
PMID:21070505 |
RGD:401976462 |
NCBI chr19:30,183,289...30,228,292
|
|
G |
Slc6a4 |
solute carrier family 6 member 4 |
disease_progression |
ISO |
DNA:VNTR |
RGD |
PMID:18552399 |
RGD:401900298 |
NCBI chr10:62,322,688...62,357,060
|
|
G |
Tas2r118 |
taste receptor, type 2, member 118 |
|
ISO |
|
OMIM |
|
|
NCBI chr 4:52,449,208...52,450,107
|
|
G |
Tbx19 |
T-box transcription factor 19 |
susceptibility |
ISO |
DNA:SNP:: (rs1003502) (human) |
RGD |
PMID:18438686 |
RGD:401851917 |
NCBI chr13:77,450,848...77,484,475
|
|
G |
Tlr2 |
toll-like receptor 2 |
|
ISO |
protein:increased expression:orbitofrontal cortex |
RGD |
PMID:23206318 |
RGD:7175526 |
NCBI chr 2:171,499,189...171,504,831
|
|
G |
Tlr3 |
toll-like receptor 3 |
|
ISO |
protein:increased expression:orbitofrontal cortex |
RGD |
PMID:23206318 |
RGD:7175526 |
NCBI chr16:53,554,916...53,572,321
|
|
G |
Tlr4 |
toll-like receptor 4 |
|
ISO |
protein:increased expression:orbitofrontal cortex |
RGD |
PMID:23206318 |
RGD:7175526 |
NCBI chr 5:85,161,247...85,174,882
|
|
G |
Ttc12 |
tetratricopeptide repeat domain 12 |
susceptibility |
ISO |
DNA:SNPs:introns,exon: |
RGD |
PMID:17761687 |
RGD:405866369 |
NCBI chr 8:58,696,381...58,743,857
|
|
|
G |
Atp2a1 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 |
|
IEP |
|
RGD |
PMID:14506614 |
RGD:1581765 |
NCBI chr 1:181,026,606...181,044,859
|
|
|
G |
Acads |
acyl-CoA dehydrogenase short chain |
susceptibility |
ISO |
DNA:SNP:: (rs1799958) (human) |
RGD |
PMID:20554694 |
RGD:401976551 |
NCBI chr12:41,493,650...41,502,897
|
|
G |
Adh1c |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16404797 |
|
NCBI chr 2:226,797,303...226,808,892
|
|
G |
Adh5 |
alcohol dehydrogenase 5 (class III), chi polypeptide |
|
IMP |
|
RGD |
PMID:8462548 |
RGD:5129091 |
NCBI chr 2:226,975,184...226,987,591
|
|
G |
Ager |
advanced glycosylation end product-specific receptor |
treatment onset |
IEP ISO |
protein:increased expression:frontal cortex neuron protein:increased expression:orbitofrontal cortex mRNA, protein:increased expression:orbitofrontal cortex, neurons |
RGD |
PMID:33716687 PMID:23867237 PMID:23867237 PMID:23867237 |
RGD:597538457, RGD:597538460, RGD:597538460, RGD:597538460 |
NCBI chr20:4,152,758...4,155,956
|
|
G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:16404797 PMID:17590986 PMID:10780266 |
RGD:734551 |
NCBI chr12:40,610,244...40,643,220
|
|
G |
Ankk1 |
ankyrin repeat and kinase domain containing 1 |
severity |
ISO |
DNA:polymorphism: :rs1800497(human) DNA:SNP,haplotype: :rs11604671, rs4938015 (human) |
RGD |
PMID:32889058 PMID:21936764 |
RGD:401940151, RGD:401959296 |
NCBI chr 8:58,676,327...58,685,012
|
|
G |
Apc2 |
APC regulator of WNT signaling pathway 2 |
|
ISO |
DNA, mRNA, protein:hypermethylation, decreased expression:brain |
RGD |
PMID:31239533 |
RGD:407987270 |
NCBI chr 7:10,043,010...10,065,037
|
|
G |
Arc |
activity-regulated cytoskeleton-associated protein |
|
ISO |
associated with Prenatal Exposure Delayed Effects and anxiety disorder:DNA:Hypermthylation:promoter |
RGD |
PMID:30016666 |
RGD:401959614 |
NCBI chr 7:108,444,959...108,448,413
|
|
G |
Avp |
arginine vasopressin |
|
IEP |
mRNA:altered expression:central amygdaloid nucleus, medial amygdaloid nucleus, medial zone of hypothalamus protein:decreased expression:suprachiasmatic nucleus |
RGD |
PMID:21575018 PMID:11709626 |
RGD:408364978, RGD:596933084 |
NCBI chr 3:138,246,544...138,248,522
|
|
G |
Bdnf |
brain-derived neurotrophic factor |
treatment |
IEP ISO |
protein:decreased expression:plasma mRNA, protein:altered expression:brain protein:decreased expression:cerebellum, hippocampus mRNA,protein:decreased expression:hippocampus, plasma (rat) protein:decreased expression:plasma (human) |
RGD |
PMID:32135570 PMID:32330588 PMID:33919862 PMID:19100286 PMID:15307153 PMID:30277635 PMID:30277635 More...
|
RGD:35673317, RGD:596936412, RGD:596933362, RGD:401976492, RGD:401965482, RGD:401938665, RGD:401938665 |
NCBI chr 3:116,619,633...116,670,212
|
|
G |
Calb1 |
calbindin 1 |
|
IEP |
mRNA:decreased expression:hippocampus (rat) |
RGD |
PMID:30277635 |
RGD:401938665 |
NCBI chr 5:29,375,624...29,402,532
|
|
G |
Camk2n1 |
calcium/calmodulin-dependent protein kinase II inhibitor 1 |
|
ISO |
mRNA:increased expression:prefrontal cortex |
RGD |
PMID:28714806 |
RGD:18337277 |
NCBI chr 5:150,674,819...150,676,600
|
|
G |
Camk4 |
calcium/calmodulin-dependent protein kinase IV |
|
IEP |
protein:decreased expression:brain, cingulate gyrus |
RGD |
PMID:11181917 |
RGD:401959326 |
NCBI chr18:24,857,152...25,076,054
|
|
G |
Cast |
calpastatin |
|
IEP |
protein:increased expression:gastrocnemius (rat) |
RGD |
PMID:28800153 |
RGD:405100967 |
NCBI chr 2:5,707,633...5,817,213
|
|
G |
Cat |
catalase |
treatment |
IEP |
associated with diabetes; protein:decreased activity;testis, epididymis (rat) associated with cardiomyopathy associated with cognitive disorder; protein:altered activity:hippocampus (rat) associated with diabetes;protein:decreased activity:liver, kidney (rat) |
RGD |
PMID:22596042 PMID:25541261 PMID:7195942 PMID:27367870 PMID:21713042 |
RGD:405255659, RGD:405255664, RGD:405255663, RGD:405255662, RGD:405255660 |
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Cckar |
cholecystokinin A receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:9922984 |
|
NCBI chr14:57,292,397...57,300,747
|
|
G |
Cdk20 |
cyclin-dependent kinase 20 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18438686 |
|
NCBI chr17:706,863...717,828
|
|
G |
Chrna3 |
cholinergic receptor nicotinic alpha 3 subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18414406 |
|
NCBI chr 8:55,401,668...55,415,165
|
|
G |
Chrna5 |
cholinergic receptor nicotinic alpha 5 subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18414406 |
|
NCBI chr 8:55,369,794...55,398,526
|
|
G |
Chrna6 |
cholinergic receptor nicotinic alpha 6 subunit |
severity |
ISO |
DNA:haplotypes: : |
RGD |
PMID:19698703 |
RGD:405849410 |
NCBI chr16:64,697,741...64,704,441
|
|
G |
Clock |
clock circadian regulator |
susceptibility |
ISO |
DNA:SNP:: (rs2412648) (human) |
RGD |
PMID:20554694 |
RGD:401976551 |
NCBI chr14:32,262,747...32,346,872
|
|
G |
Cnr1 |
cannabinoid receptor 1 |
sexual_dimorphism |
IEP |
associated with chronic stress in female rats |
RGD |
PMID:27894930 |
RGD:401959751 |
NCBI chr 5:53,204,867...53,230,396
|
|
G |
Comt |
catechol-O-methyltransferase |
disease_progression |
ISO |
CTD Direct Evidence: marker/mechanism DNA:polymorphism: :rs4680(human) DNA:polymorphism:: |
CTD RGD |
PMID:10395222 PMID:32889058 PMID:10395222 |
RGD:401940151, RGD:401940114 |
NCBI chr11:96,072,371...96,091,956
|
|
G |
Creb1 |
cAMP responsive element binding protein 1 |
sexual_dimorphism |
IEP IDA |
mRNA, protein:decreased expression:amygdala protein:increased phosphorylation:liver protein:altered expression, altered phosphorylation:liver, nucleus |
RGD |
PMID:29991681 PMID:31262967 PMID:22269225 |
RGD:401938626, RGD:401959334, RGD:401959317 |
NCBI chr 9:73,397,333...73,466,339
|
|
G |
Crebbp |
CREB binding protein |
|
IEP |
mRNA, protein:decreased expression:amygdala |
RGD |
PMID:29991681 |
RGD:401938626 |
NCBI chr10:11,842,307...11,968,266
|
|
G |
Crh |
corticotropin releasing hormone |
|
IEP |
mRNA:increased expression:central amygdaloid nucleus (rat) |
RGD |
PMID:20060104 |
RGD:5508173 |
NCBI chr 2:104,059,184...104,061,048
|
|
G |
Crhr1 |
corticotropin releasing hormone receptor 1 |
|
ISO |
|
RGD |
PMID:11988580 |
RGD:734822 |
NCBI chr10:89,540,192...89,583,466
|
|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
|
ISO IEP |
CTD Direct Evidence: marker/mechanism protein:increased expression:plasma, extracellular exosome |
CTD RGD |
PMID:20843640 PMID:23819932 PMID:29404485 PMID:29404485 |
RGD:14700915, RGD:14700911, RGD:14700911 |
NCBI chr 1:205,269,967...205,280,365
|
|
G |
Dbh |
dopamine beta-hydroxylase |
no_association |
ISO |
DNA:polymorphism:5' utr:g.-1021C>T (human) DNA:polymorphism:cds:g.444G>A (human) |
RGD |
PMID:16133787 PMID:16252068 |
RGD:1625572, RGD:1625571 |
NCBI chr 3:30,886,313...30,903,313
|
|
G |
Dbi |
diazepam binding inhibitor |
|
ISO |
mRNA,protein:increased expression:cerebral cortex (mouse) |
RGD |
PMID:9526063 |
RGD:408346747 |
NCBI chr13:33,794,231...33,802,632
|
|
G |
Dcx |
doublecortin |
|
IEP |
mRNA:decreased expression:hippocampus (rat) |
RGD |
PMID:30277635 |
RGD:401938665 |
NCBI chr X:107,430,767...107,573,612
|
|
G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
|
ISO |
associated with Prenatal Exposure Delayed Effects and anxiety disorder:mRNA,protein:decreased expression:brain (mouse) |
RGD |
PMID:30016666 |
RGD:401959614 |
NCBI chr10:55,239,397...55,267,780
|
|
G |
Drd2 |
dopamine receptor D2 |
|
IEA |
|
GAD |
PMID:15118671 |
RGD:1331525 |
NCBI chr 8:58,605,403...58,669,339
|
|
G |
Drd4 |
dopamine receptor D4 |
treatment susceptibility |
ISO |
DNA:repeats:exon: associated with peer pressure;DNA:repeats:exon: |
RGD |
PMID:25640830 PMID:26307243 |
RGD:11064848, RGD:401959598 |
NCBI chr 1:205,825,937...205,829,124
|
|
G |
Ep300 |
E1A binding protein p300 |
|
IEP |
mRNA, protein:decreased expression:amygdala |
RGD |
PMID:29991681 |
RGD:401938626 |
NCBI chr 7:114,987,857...115,058,652
|
|
G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
|
IEP |
|
RGD |
PMID:23095216 |
RGD:10045658 |
NCBI chr 1:78,971,310...79,007,963
|
|
G |
Fgf2 |
fibroblast growth factor 2 |
|
IMP |
|
RGD |
PMID:28821667 PMID:31375540 |
RGD:405855870, RGD:405855874 |
NCBI chr 2:122,164,454...122,218,796
|
|
G |
Fmr1 |
fragile X messenger ribonucleoprotein 1 |
|
IEP |
mRNA:increased expression:cerebellum |
RGD |
PMID:34453331 |
RGD:401938639 |
NCBI chr X:147,240,239...147,278,057
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
treatment |
IEP IDA ISO |
protein:increased expression:brain protein:increased expression:parvocellular oculomotor nucleus |
RGD |
PMID:14741756 PMID:29210146 PMID:11164784 |
RGD:405255650, RGD:405295495, RGD:405255652 |
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
treatment |
IEP ISO |
protein:increased expression:dorsal striatum (mouse) protein:increased expression:brain (mouse) |
RGD |
PMID:22792289 PMID:27380261 PMID:9835277 |
RGD:401851082, RGD:401901287, RGD:401901184 |
NCBI chr 1:88,082,324...88,089,506
|
|
G |
Fshb |
follicle stimulating hormone subunit beta |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:8590623 |
|
NCBI chr 3:114,003,262...114,007,072
|
|
G |
Gabbr1 |
gamma-aminobutyric acid type B receptor subunit 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22253714 |
|
NCBI chr20:1,469,779...1,499,352
|
|
G |
Gabbr2 |
gamma-aminobutyric acid type B receptor subunit 2 |
susceptibility |
ISO |
DNA:SNP:intron: (rs2900512) (human) |
RGD |
PMID:28118741 |
RGD:401940105 |
NCBI chr 5:60,947,517...61,288,104
|
|
G |
Gabra2 |
gamma-aminobutyric acid type A receptor subunit alpha 2 |
susceptibility |
ISO |
DNA:SNPs:multiple: CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:22253714 PMID:15024690 |
RGD:6480257 |
NCBI chr14:37,451,218...37,587,458
|
|
G |
Gabrb3 |
gamma-aminobutyric acid type A receptor subunit beta 3 |
susceptibility |
ISO |
DNA:CA repeats: :(human) |
RGD |
PMID:9858031 |
RGD:405866342 |
NCBI chr 1:117,602,772...117,838,230
|
|
G |
Gabrg2 |
gamma-aminobutyric acid type A receptor subunit gamma 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22253714 |
|
NCBI chr10:26,876,926...26,965,523
|
|
G |
Gata4 |
GATA binding protein 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20585342 |
|
NCBI chr15:41,635,572...41,707,252
|
|
G |
Gdnf |
glial cell derived neurotrophic factor |
treatment |
ISO IEP IDA |
protein:increased expression:serum associated with Tobacco Use Disorder;mRNA:decreased expression:ventral tegmental area DNA:hypomethylation:nucleus accumbens |
RGD |
PMID:25623403 PMID:28559549 PMID:22238721 PMID:31710958 |
RGD:401965480, RGD:405850249, RGD:405849387, RGD:405820205 |
NCBI chr 2:58,621,327...58,647,242
|
|
G |
Ggt1 |
gamma-glutamyltransferase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12747453 |
|
NCBI chr20:13,074,695...13,104,095
|
|
G |
Ghsr |
growth hormone secretagogue receptor |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:23977009 |
|
NCBI chr 2:110,268,489...110,271,865
|
|
G |
Gphn |
gephyrin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22253714 |
|
NCBI chr 6:96,954,365...97,483,617
|
|
G |
Gria1 |
glutamate ionotropic receptor AMPA type subunit 1 |
|
ISO IEP |
protein:increased phosphorylation:lumbar spinal cord (mouse) protein:decreased expression:neocortex (rat) protein:increased expression, increased phosphorylation:cingulate cortex (rat) protein:increased expression:nucleus accumbens (mouse) protein:increased expression:nucleus accumbens (rat) |
RGD |
PMID:28585190 PMID:12036520 PMID:34280506 PMID:21041654 PMID:21041654 |
RGD:405100727, RGD:405820203, RGD:405818275, RGD:405650686, RGD:405650686 |
NCBI chr10:41,710,540...42,030,105
|
|
G |
Gria2 |
glutamate ionotropic receptor AMPA type subunit 2 |
|
IEP |
protein:decreased expression:neocortex (rat) protein:increased expression:ventral CA1 field of hippocampus (rat) |
RGD |
PMID:12036520 PMID:30481568 |
RGD:405820203, RGD:596933081 |
NCBI chr 2:168,247,490...168,367,616
|
|
G |
Grin1 |
glutamate ionotropic receptor NMDA type subunit 1 |
|
ISO |
|
RGD |
PMID:14573320 |
RGD:1642372 |
NCBI chr 3:28,501,836...28,528,754
|
|
G |
Grin2b |
glutamate ionotropic receptor NMDA type subunit 2B |
|
ISO |
|
RGD |
PMID:14573320 PMID:16911840 |
RGD:1642372, RGD:1642200 |
NCBI chr 4:170,297,811...170,775,420
|
|
G |
Hdac2 |
histone deacetylase 2 |
|
IMP |
|
RGD |
PMID:23485013 |
RGD:9590265 |
NCBI chr20:42,101,815...42,126,486
|
|
G |
Hmgb1 |
high mobility group box 1 |
onset |
ISO IEP |
protein:increased expression:orbitofrontal cortex protein:increased expression:frontal cortex neuron |
RGD |
PMID:23867237 PMID:23867237 |
RGD:597538460, RGD:597538460 |
NCBI chr12:11,009,236...11,015,941
|
|
G |
Htr1a |
5-hydroxytryptamine receptor 1A |
treatment |
IMP |
|
RGD |
PMID:9631953 |
RGD:401900760 |
NCBI chr 2:38,427,169...38,431,733
|
|
G |
Htr1b |
5-hydroxytryptamine receptor 1B |
sexual_dimorphism onset no_association |
ISO |
associated with attention deficit hyperactivity disorder;DNA:SNP: :rs11568817(human) DNA:SNP: :rs13212041 (human) DNA:SNPs: :multiples (human) |
RGD |
PMID:28923721 PMID:30774345 PMID:11496363 |
RGD:405650695, RGD:405847403, RGD:405818272 |
NCBI chr 8:91,395,405...91,414,815
|
|
G |
Htr2a |
5-hydroxytryptamine receptor 2A |
treatment |
ISO IMP IEP |
CTD Direct Evidence: marker/mechanism protein:increased expression:dorsal raphe, nucleus accumbens mRNA, protein:decreased expression:cerebral cortex, liver |
CTD RGD |
PMID:9631953 PMID:9347073 PMID:9347075 PMID:20501057 |
RGD:401900760, RGD:401900742, RGD:401900740, RGD:401900301 |
NCBI chr15:56,360,647...56,428,703
|
|
G |
Htr2c |
5-hydroxytryptamine receptor 2C |
treatment |
IDA |
|
RGD |
PMID:24041931 |
RGD:401900761 |
NCBI chr X:115,453,190...115,682,325
|
|
G |
Htr3a |
5-hydroxytryptamine receptor 3A |
|
ISO |
DNA:hypermethylation, hypomethylation:promoter: (mouse) |
RGD |
PMID:22834954 |
RGD:404976877 |
NCBI chr 8:58,138,514...58,150,960
|
|
G |
Htr3b |
5-hydroxytryptamine receptor 3B |
susceptibility |
ISO |
DNA:SNP:cds:rs1176744(human) |
RGD |
PMID:20838391 |
RGD:6480660 |
NCBI chr 8:49,279,291...49,308,444
|
|
G |
Htr7 |
5-hydroxytryptamine receptor 7 |
|
ISO |
DNA:SNP:intron: (rs7916403) (human) |
RGD |
PMID:21184583 |
RGD:150429835 |
NCBI chr 1:243,049,064...243,173,636
|
|
G |
Igf2 |
insulin-like growth factor 2 |
|
ISO |
protein:decreased expression:plasma (human) |
RGD |
PMID:30277635 |
RGD:401938665 |
NCBI chr 1:197,814,409...197,831,802
|
|
G |
Il10 |
interleukin 10 |
|
IEP |
mRNA:increased expression:liver |
RGD |
PMID:22269225 |
RGD:401959317 |
NCBI chr13:45,024,921...45,029,586
|
|
G |
Il6 |
interleukin 6 |
|
ISO |
protein:increased expression:respiratory system fluid/secretion |
RGD |
PMID:26208141 |
RGD:11342768 |
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Kcnj6 |
potassium inwardly-rectifying channel, subfamily J, member 6 |
|
ISO |
DNA:SNP:promoter:rs2836016 (human) |
RGD |
PMID:21307845 |
RGD:6483053 |
NCBI chr11:47,531,312...47,778,348
|
|
G |
Kcnn2 |
potassium calcium-activated channel subfamily N member 2 |
|
IEP |
protein:decreased expression:ventral CA1 field of hippocampus (rat) |
RGD |
PMID:30481568 |
RGD:596933081 |
NCBI chr18:40,004,693...40,445,043
|
|
G |
Lhb |
luteinizing hormone subunit beta |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:8590623 |
|
NCBI chr 1:105,037,457...105,038,446
|
|
G |
Maoa |
monoamine oxidase A |
susceptibility |
ISO |
|
RGD |
PMID:15900229 |
RGD:1600720 |
NCBI chr X:8,615,239...8,681,372
|
|
G |
Mapk1 |
mitogen activated protein kinase 1 |
|
IEP |
protein:increased expression:liver |
RGD |
PMID:31262967 |
RGD:401959334 |
NCBI chr11:97,462,025...97,529,193
|
|
G |
Mapk14 |
mitogen activated protein kinase 14 |
|
ISO |
protein:increased expression, increased phosphorylation:liver |
RGD |
PMID:31262967 |
RGD:401959334 |
NCBI chr20:6,751,288...6,812,294
|
|
G |
Mapk3 |
mitogen activated protein kinase 3 |
|
IEP |
protein:increased expression:liver |
RGD |
PMID:31262967 |
RGD:401959334 |
NCBI chr 1:190,797,189...190,803,411
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
|
IDA |
|
RGD |
PMID:31262967 |
RGD:401959334 |
NCBI chr16:8,645,171...8,728,225
|
|
G |
Mb |
myoglobin |
|
ISO |
protein:decreased expression:serum |
RGD |
PMID:3766421 |
RGD:458925288 |
NCBI chr 7:110,640,511...110,647,742
|
|
G |
Mcm5 |
minichromosome maintenance complex component 5 |
|
IEP |
|
RGD |
PMID:23095216 |
RGD:10045658 |
NCBI chr19:13,488,813...13,510,131
|
|
G |
Mir191 |
microRNA 191 |
onset |
IEP |
|
RGD |
PMID:32135570 |
RGD:35673317 |
NCBI chr 8:109,264,098...109,264,188
|
|
G |
Mir195 |
microRNA 195 |
onset |
IEP |
|
RGD |
PMID:32135570 |
RGD:35673317 |
NCBI chr10:54,951,838...54,951,924
|
|
G |
Mir206 |
microRNA 206 |
onset |
IEP |
|
RGD |
PMID:32135570 |
RGD:35673317 |
NCBI chr 9:23,094,249...23,094,332
|
|
G |
Mir30a |
microRNA 30a |
onset |
IEP |
|
RGD |
PMID:32135570 |
RGD:35673317 |
NCBI chr 9:25,737,600...25,737,670
|
|
G |
Mki67 |
marker of proliferation Ki-67 |
|
IEP |
mRNA:decreased expression:hippocampus (rat) |
RGD |
PMID:30277635 |
RGD:401938665 |
NCBI chr 1:199,926,150...199,952,847
|
|
G |
Mmp2 |
matrix metallopeptidase 2 |
|
IEP |
|
RGD |
PMID:24966898 |
RGD:13207311 |
NCBI chr19:30,327,643...30,355,856
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
|
IEP |
|
RGD |
PMID:24966898 |
RGD:13207311 |
NCBI chr 3:174,103,474...174,111,434
|
|
G |
Ncam1 |
neural cell adhesion molecule 1 |
sexual_dimorphism treatment |
IEP |
mRNA:decreased expression:hippocampus (rat) associated with chronic stress in female rats |
RGD |
PMID:30277635 PMID:27894930 PMID:16207289 |
RGD:401938665, RGD:401959751, RGD:401959613 |
NCBI chr 8:58,762,088...59,062,131
|
|
G |
Ngf |
nerve growth factor |
|
ISO IEP |
protein:increased expression:serum protein:decreased expression:cerebral cortex, hippocampus protein:decreased expression:brain |
RGD |
PMID:25623403 PMID:19100286 PMID:15307153 |
RGD:401965480, RGD:401976492, RGD:401965482 |
NCBI chr 2:192,589,580...192,642,971
|
|
G |
Npy |
neuropeptide Y |
|
IAGP ISO |
DNA:deletion:intron:g.4666_4674del (rat) CTD Direct Evidence: marker/mechanism DNA:missense mutation: :p.L7P (human) |
CTD RGD |
PMID:17572454 PMID:15749341 PMID:12215082 |
RGD:1357412, RGD:10430830 |
NCBI chr 4:80,212,111...80,219,310
|
|
G |
Npy2r |
neuropeptide Y receptor Y2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18828811 |
|
NCBI chr 2:167,901,999...167,912,165
|
|
G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
treatment |
IDA IEP IMP |
protein:decreased expression, decreased DNA binding:brain mRNA, protein:decreased expression:placenta |
RGD |
PMID:11961084 PMID:21143252 PMID:31756338 PMID:33920737 |
RGD:408345232, RGD:408345244, RGD:408345241, RGD:408345239 |
NCBI chr18:31,522,783...31,644,508
|
|
G |
Nr3c2 |
nuclear receptor subfamily 3, group C, member 2 |
treatment sexual_dimorphism |
IMP |
|
RGD |
PMID:29437012 PMID:30171933 PMID:33007359 |
RGD:401965466, RGD:401976281, RGD:401966865 |
NCBI chr19:47,619,853...47,964,089
|
|
G |
Nrg1 |
neuregulin 1 |
sexual_dimorphism |
ISO |
in female, associated with stressful life event;DNA:SNP: :rs6994992(human) |
RGD |
PMID:27353026 |
RGD:405100235 |
NCBI chr16:65,954,084...67,007,484
|
|
G |
Ntf3 |
neurotrophin 3 |
|
ISO IEP |
protein:decreased expression:plasma (human) protein:increased expression:brain mRNA,protein:decreased expression:hippocampus, plasma (rat) |
RGD |
PMID:30277635 PMID:15307153 PMID:30277635 |
RGD:401938665, RGD:401965482, RGD:401938665 |
NCBI chr 4:158,914,984...158,984,453
|
|
G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
treatment |
ISO IEP IDA |
associated with Prenatal Exposure Delayed Effects and anxiety disorder:protein:decreased acetylation:brain |
RGD |
PMID:30016666 PMID:33919862 PMID:32206827 PMID:8840027 |
RGD:401959614, RGD:596933362, RGD:596933095, RGD:401965407 |
NCBI chr17:5,560,558...5,875,899
|
|
G |
Oprd1 |
opioid receptor, delta 1 |
|
IEP ISO IMP |
associated with stress-related disorder; mRNA:decreased expression:dorsal striatum (rat) DNA:SNPs, haplotype:intron 1:multiple (human) |
RGD |
PMID:28511993 PMID:24533225 PMID:7501658 |
RGD:401976432, RGD:402525443, RGD:401976439 |
NCBI chr 5:149,590,244...149,624,999
|
|
G |
Oprk1 |
opioid receptor, kappa 1 |
severity susceptibility no_association |
ISO IEP |
DNA:SNP, haplotype: :rs6473797 (human) associated with stress-related disorder; mRNA:decreased expression:dorsal striatum (rat) DNA:SNP: :rs6473797 (human) DNA:SNP: :rs997917 (human) |
RGD |
PMID:31004399 PMID:28511993 PMID:37177778 PMID:37177778 |
RGD:401831037, RGD:401976432, RGD:401850581, RGD:401850581 |
NCBI chr 5:18,657,866...18,675,671
|
|
G |
Oprl1 |
opioid related nociceptin receptor 1 |
|
IMP |
|
RGD |
PMID:11814626 |
RGD:9835016 |
NCBI chr 3:189,209,495...189,225,406
|
|
G |
Oprm1 |
opioid receptor, mu 1 |
treatment no_association |
ISO |
CTD Direct Evidence: marker/mechanism DNA:missense mutation:exon:p.N40D (118A>G) (rs 1799971) (human) DNA:missense mutations, SNP:exon, intron:p.A6V, p.S147C, p.N40D (118A>G) (rs 1799971), IVS2+691G>C (human) DNA:SNP: :rs510769 |
CTD RGD |
PMID:12815747 PMID:32772383 PMID:9399694 PMID:26042510 |
RGD:401827947, RGD:401827934, RGD:401827930 |
NCBI chr 1:45,565,371...45,818,722
|
|
G |
Oxtr |
oxytocin receptor |
sexual_dimorphism |
ISO |
DNA:SNP:intron: (rs53576) (human) DNA:hypomethylation |
RGD |
PMID:27716573 PMID:35146961 |
RGD:597538589, RGD:597538605 |
NCBI chr 4:147,154,374...147,171,723
|
|
G |
Pde4b |
phosphodiesterase 4B |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18438686 |
|
NCBI chr 5:122,028,956...122,598,267
|
|
G |
Pdyn |
prodynorphin |
no_association susceptibility |
ISO IEP |
CTD Direct Evidence: marker/mechanism mRNA, protein:decreased expression:hippocampus, granule cell DNA:SNPs: :rs2281285, rs2225749, rs910080 (human) DNA:SNP: :rs2281285 (human) DNA, mRNA:SNP, decreased expression:promoter, dorsolateral prefrontal cortex:rs1997794 (human) associated with cocaine dependence;DNA, mRNA:SNPs, haplotype:3' utr:rs910080, rs910079, rs2235749 (human) |
CTD RGD |
PMID:17559549 PMID:18923396 PMID:1589146 PMID:37177778 PMID:36099111 PMID:29925858 PMID:18923396 More...
|
RGD:401851059, RGD:401850581, RGD:401850566, RGD:401850559, RGD:401850550 |
NCBI chr 3:137,354,161...137,366,503
|
|
G |
Penk |
proenkephalin |
|
IEP |
mRNA:increased expression:frontal lobe: |
RGD |
PMID:22703995 |
RGD:10003152 |
NCBI chr 5:21,981,381...21,987,074
|
|
G |
Per1 |
period circadian regulator 1 |
|
IEP |
mRNA:altered expression: arcuate nucleus of hypothalamus |
RGD |
PMID:15009656 |
RGD:407572515 |
NCBI chr10:54,299,002...54,313,804
|
|
G |
Per2 |
period circadian regulator 2 |
|
IEP |
mRNA:altered expression: arcuate nucleus of hypothalamus, suprachiasmatic nucleus |
RGD |
PMID:15009656 |
RGD:407572515 |
NCBI chr 9:99,454,828...99,497,069
|
|
G |
Per3 |
period circadian regulator 3 |
|
IEP |
mRNA:altered expression:suprachiasmatic nucleus |
RGD |
PMID:15009656 |
RGD:407572515 |
NCBI chr 5:166,740,914...166,778,243
|
|
G |
Pomc |
proopiomelanocortin |
sexual_dimorphism |
IEP ISO |
protein:decreased expression:brain (rat) mRNA:altered expression: arcuate nucleus of hypothalamus associated with Prenatal Exposure Delayed Effects;mRNA:altered expression:adenohypophysis protein:increased expression:plasma mRNA, protein:increased expression:arcuate nucleus, hypothalamus, septum DNA, mRNA:deletion, decreased expression:enhancer, hypothalamus mRNA:increased expression: hypothalamus, pituitary gland, shell of nucleus accumbens |
RGD |
PMID:18162070 PMID:15009656 PMID:19912941 PMID:19912941 PMID:7925590 PMID:31339663 PMID:22724395 More...
|
RGD:401976284, RGD:407572515, RGD:407572513, RGD:407572513, RGD:407571692, RGD:407550221, RGD:405878072 |
NCBI chr 6:32,659,137...32,665,175
|
|
G |
Rest |
RE1-silencing transcription factor |
|
ISO |
protein:increased expression:basal forebrain |
RGD |
PMID:37402853 |
RGD:597538603 |
NCBI chr14:30,859,109...30,879,828
|
|
G |
Rpl18a |
ribosomal protein L18A |
|
IEP |
mRNA:decreased expression:parietal cortex |
RGD |
PMID:11244494 |
RGD:11038708 |
NCBI chr16:18,576,467...18,578,653
|
|
G |
Sell |
selectin L |
|
ISO |
protein:decreased expression:Tcell |
RGD |
PMID:7573774 |
RGD:597015763 |
NCBI chr13:78,950,100...78,969,604
|
|
G |
Shbg |
sex hormone binding globulin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:8590623 |
|
NCBI chr10:54,332,939...54,350,409
|
|
G |
Slc6a3 |
solute carrier family 6 member 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27219321 |
|
NCBI chr 1:31,537,990...31,578,962
|
|
G |
Slc6a4 |
solute carrier family 6 member 4 |
susceptibility |
ISO |
protein:decreased activity: : CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:15520362 PMID:17000009 PMID:20838391 |
RGD:6480660 |
NCBI chr10:62,322,688...62,357,060
|
|
G |
Snca |
synuclein alpha |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18055133 |
|
NCBI chr 4:91,026,474...91,127,444
|
|
G |
Sod1 |
superoxide dismutase 1 |
|
IEP |
associated with diabetes; protein:decreased activity;testis, epididymis (rat) |
RGD |
PMID:25541261 |
RGD:405255664 |
NCBI chr11:42,942,742...42,948,399
|
|
G |
Sox2 |
SRY-box transcription factor 2 |
|
IEP |
mRNA:decreased expression:hippocampus (rat) |
RGD |
PMID:30277635 |
RGD:401938665 |
NCBI chr 2:117,536,929...117,539,340
|
|
G |
Spi1 |
Spi-1 proto-oncogene |
treatment |
IEP IDA |
protein:decreased expression:alveolar macrophage |
RGD |
PMID:16272341 PMID:21447000 |
RGD:9586723, RGD:9586725 |
NCBI chr 3:77,059,744...77,093,730
|
|
G |
Spn |
sialophorin |
|
ISO |
associated with Prenatal Exposure Delayed Effects and anxiety disorder:DNA:Hypermthylation:promoter |
RGD |
PMID:30016666 |
RGD:401959614 |
NCBI chr 1:181,746,937...181,759,564
|
|
G |
St6gal1 |
ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
severity |
ISO |
mRNA,protein:decreased expression:liver: |
RGD |
PMID:17697868 |
RGD:10043133 |
NCBI chr11:77,526,837...77,653,474
|
|
G |
Syp |
synaptophysin |
sexual_dimorphism |
IEP |
associated with chronic stress in female rats |
RGD |
PMID:27894930 |
RGD:401959751 |
NCBI chr X:17,521,348...17,536,449
|
|
G |
Tacr1 |
tachykinin receptor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19204064 |
|
NCBI chr 4:116,478,617...116,647,492
|
|
G |
Tacr3 |
tachykinin receptor 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18422838 |
|
NCBI chr 2:223,266,536...223,363,791
|
|
G |
Tas2r118 |
taste receptor, type 2, member 118 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16385453 PMID:17250611 |
|
NCBI chr 4:52,449,208...52,450,107
|
|
G |
Tas2r138 |
taste receptor, type 2, member 138 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17250611 |
|
NCBI chr 4:69,428,344...69,429,339
|
|
G |
Tbx19 |
T-box transcription factor 19 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18438686 |
|
NCBI chr13:77,450,848...77,484,475
|
|
G |
Tf |
transferrin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:11000917 PMID:21792595 |
|
NCBI chr 8:103,789,780...103,816,487
|
|
G |
Timeless |
timeless circadian regulator |
susceptibility |
ISO |
DNA:SNP:: (rs2291738) (human) |
RGD |
PMID:20554694 |
RGD:401976551 |
NCBI chr 7:654,804...678,769
|
|
G |
Tlr2 |
toll-like receptor 2 |
|
IEP ISO |
protein:decreased expression:alveolar macrophage mRNA:increased expression:orbitofrontal cortex mRNA:increased expression:liver protein:decreased expression:blood, monocyte mRNA:increased expression:respiratory system fluid/secretion |
RGD |
PMID:36281822 PMID:34415075 PMID:30756376 PMID:27256567 PMID:26208141 |
RGD:597538461, RGD:597538499, RGD:597538493, RGD:597538485, RGD:11342768 |
NCBI chr 2:171,499,189...171,504,831
|
|
G |
Tlr3 |
toll-like receptor 3 |
|
ISO |
mRNA:increased expression:orbitofrontal cortex |
RGD |
PMID:34415075 |
RGD:597538499 |
NCBI chr16:53,554,916...53,572,321
|
|
G |
Tlr4 |
toll-like receptor 4 |
onset |
ISO IEP |
mRNA:decreased expression:respiratory system fluid/secretion protein:increased expression:frontal cortex neuron protein:increased expression:orbitofrontal cortex mRNA:increased expression:orbitofrontal cortex mRNA:increased expression:liver protein:increased expression:liver protein:decreased expression:blood, monocyte |
RGD |
PMID:26208141 PMID:23867237 PMID:23867237 PMID:34415075 PMID:30756376 PMID:21276439 PMID:27256567 More...
|
RGD:11342768, RGD:597538460, RGD:597538460, RGD:597538499, RGD:597538493, RGD:150540306, RGD:597538485 |
NCBI chr 5:85,161,247...85,174,882
|
|
G |
Tlr5 |
toll-like receptor 5 |
|
ISO |
mRNA:increased expression:orbitofrontal cortex |
RGD |
PMID:34415075 |
RGD:597538499 |
NCBI chr13:97,166,430...97,190,642
|
|
G |
Tlr6 |
toll-like receptor 6 |
|
ISO |
mRNA:increased expression:orbitofrontal cortex |
RGD |
PMID:34415075 |
RGD:597538499 |
NCBI chr14:43,715,809...43,727,019
|
|
G |
Tlr7 |
toll-like receptor 7 |
|
ISO |
mRNA:increased expression:orbitofrontal cortex |
RGD |
PMID:34415075 |
RGD:597538499 |
NCBI chr X:30,644,324...30,670,796
|
|
G |
Tlr8 |
toll-like receptor 8 |
|
ISO |
mRNA:increased expression:orbitofrontal cortex |
RGD |
PMID:34415075 |
RGD:597538499 |
NCBI chr X:30,708,714...30,733,104
|
|
G |
Tlr9 |
toll-like receptor 9 |
|
ISO |
mRNA:increased expression:orbitofrontal cortex |
RGD |
PMID:34415075 |
RGD:597538499 |
NCBI chr 8:115,743,407...115,747,523
|
|
G |
Tph1 |
tryptophan hydroxylase 1 |
|
ISO |
|
RGD |
PMID:15654285 |
RGD:1580464 |
NCBI chr 1:97,157,375...97,178,415
|
|
G |
Vip |
vasoactive intestinal peptide |
susceptibility |
ISO |
DNA:SNPs, haplotype:: (rs3823082,rs688136) (human) |
RGD |
PMID:20554694 |
RGD:401976551 |
NCBI chr 1:44,470,232...44,478,561
|
|
|
G |
Cck |
cholecystokinin |
susceptibility |
ISO |
DNA:SNP:promoter: -45C>T (human) |
RGD |
PMID:10235270 |
RGD:406351024 |
NCBI chr 8:121,153,499...121,160,194
|
|
G |
Cnr1 |
cannabinoid receptor 1 |
|
ISO |
|
RGD |
PMID:11841893 |
RGD:1626329 |
NCBI chr 5:53,204,867...53,230,396
|
|
G |
Ngf |
nerve growth factor |
|
ISO |
protein:increased expression:serum |
RGD |
PMID:17434673 |
RGD:401965399 |
NCBI chr 2:192,589,580...192,642,971
|
|
G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
|
ISO |
|
RGD |
PMID:16318954 |
RGD:5688289 |
NCBI chr13:64,714,063...64,722,320
|
|
G |
Slc6a3 |
solute carrier family 6 member 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27219321 |
|
NCBI chr 1:31,537,990...31,578,962
|
|
|
G |
Cacna1d |
calcium voltage-gated channel subunit alpha1 D |
susceptibility |
IEP |
mRNA, protein:increased expression:inferior colliculus (rat) |
RGD |
PMID:25556199 |
RGD:152985539 |
NCBI chr16:5,227,157...5,521,163
|
|
G |
Drd2 |
dopamine receptor D2 |
susceptibility |
ISO |
DNA:SNP:exon:A>G(human) |
RGD |
PMID:23238469 |
RGD:401959213 |
NCBI chr 8:58,605,403...58,669,339
|
|
G |
Pdyn |
prodynorphin |
|
ISO |
mRNA:increased expression:brain |
RGD |
PMID:15869750 |
RGD:401850576 |
NCBI chr 3:137,354,161...137,366,503
|
|
G |
Slc29a1 |
solute carrier family 29 member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:21283641 |
|
NCBI chr 9:22,897,099...22,911,640
|
|
G |
Slc6a3 |
solute carrier family 6 member 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27219321 |
|
NCBI chr 1:31,537,990...31,578,962
|
|
|
G |
Avp |
arginine vasopressin |
|
IEP ISO |
protein:decreased expression:suprachiasmatic nucleus DNA:hypermethylation:promoter |
RGD |
PMID:11709626 PMID:24356727 |
RGD:596933084, RGD:596933307 |
NCBI chr 3:138,246,544...138,248,522
|
|
G |
Bdnf |
brain-derived neurotrophic factor |
severity |
ISO IEP |
protein:increased expression:hippocampus, prefrontal cortex |
RGD |
PMID:20553781 PMID:26659122 |
RGD:405849399, RGD:596936245 |
NCBI chr 3:116,619,633...116,670,212
|
|
G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
severity |
ISO |
mRNA:decreased expression:peripheral blood mononuclear cells (human) |
RGD |
PMID:20735373 |
RGD:401976556 |
NCBI chr 1:176,766,222...176,864,741
|
|
G |
Clock |
clock circadian regulator |
severity |
ISO |
mRNA:decreased expression:peripheral blood mononuclear cells (human) |
RGD |
PMID:20735373 |
RGD:401976556 |
NCBI chr14:32,262,747...32,346,872
|
|
G |
Cry1 |
cryptochrome circadian regulator 1 |
severity |
ISO |
mRNA:decreased expression:peripheral blood mononuclear cells (human) |
RGD |
PMID:20735373 |
RGD:401976556 |
NCBI chr 7:18,529,823...18,594,092
|
|
G |
Cry2 |
cryptochrome circadian regulator 2 |
|
ISO |
mRNA:decreased expression:Peripheral blood mononuclear cell (human) |
RGD |
PMID:20735373 |
RGD:401976556 |
NCBI chr 3:98,830,479...98,860,437
|
|
G |
Cyp2c6 |
cytochrome P450, family 2, subfamily C, polypeptide 6 |
no_association treatment |
ISO |
DNA:SNPs::CYP2C19*2 (681G>A,rs4244285), CYP2C19*3 (636G>A, rs4986893),CYP2C19*17 (-806C>T, rs12248560) (human) DNA:SNP:promoter:CYP2C19*17 (-806C>T,rs12248560)(human) DNA:SNP:cds:CYP2C19*2 (681G>A,rs4244285)(human) |
RGD |
PMID:27099220 PMID:30325732 PMID:31957548 |
RGD:401960863, RGD:401960882, RGD:401960880 |
NCBI chr 1:247,879,058...247,916,804
|
|
G |
Dbi |
diazepam binding inhibitor |
|
ISO |
mRNA,protein:increased expression:cerebral cortex (mouse) |
RGD |
PMID:9526063 |
RGD:408346747 |
NCBI chr13:33,794,231...33,802,632
|
|
G |
Drd4 |
dopamine receptor D4 |
severity |
ISO |
DNA:repeats:exon: |
RGD |
PMID:20359751 |
RGD:401959612 |
NCBI chr 1:205,825,937...205,829,124
|
|
G |
Fkbp5 |
FKBP prolyl isomerase 5 |
severity |
ISO |
DNA:SNPs,haplotypes:multiple |
RGD |
PMID:24603855 |
RGD:401976481 |
NCBI chr20:6,458,931...6,577,227
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
treatment |
IEP |
protein:altered expression:brain |
RGD |
PMID:26727528 PMID:31778691 |
RGD:405101372, RGD:405255665 |
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
disease_progression |
ISO |
protein:increased expression:primary motor cortex, secondary motor cortex, ventral tegmental area (mouse) |
RGD |
PMID:24355551 |
RGD:401851085 |
NCBI chr 1:88,082,324...88,089,506
|
|
G |
Gabrg2 |
gamma-aminobutyric acid type A receptor subunit gamma 2 |
|
IEP |
mRNA, protein:increased expression:hippocampus (rat) |
RGD |
PMID:12488536 |
RGD:402528882 |
NCBI chr10:26,876,926...26,965,523
|
|
G |
Gdnf |
glial cell derived neurotrophic factor |
|
IDA |
mRNA, DNA:altered expression, hypomethylation:brain |
RGD |
PMID:31710958 |
RGD:405820205 |
NCBI chr 2:58,621,327...58,647,242
|
|
G |
Gria1 |
glutamate ionotropic receptor AMPA type subunit 1 |
|
IEP |
protein:increased phosphorylation:lateral habenular nucleus (rat) |
RGD |
PMID:28865912 |
RGD:405650672 |
NCBI chr10:41,710,540...42,030,105
|
|
G |
Ngf |
nerve growth factor |
|
ISO |
protein:increased expression:plasma |
RGD |
PMID:8727238 |
RGD:401976550 |
NCBI chr 2:192,589,580...192,642,971
|
|
G |
Npy1r |
neuropeptide Y receptor Y1 |
|
IEP |
mRNA:decreased expression:hippocampus, cerebral cortex (rat) |
RGD |
PMID:20028355 |
RGD:10448926 |
NCBI chr16:27,804,416...27,814,070
|
|
G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
|
IDA ISO IEP |
protein:decreased phosphorylation:prefrontal cortex protein:decreased expression:cingulate gyrus |
RGD |
PMID:25732140 PMID:18801418 PMID:11961084 |
RGD:408345231, RGD:408345247, RGD:408345232 |
NCBI chr18:31,522,783...31,644,508
|
|
G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
treatment |
IDA IEP |
associated with Binge Drinking protein:increased phopsphorylation, increased expression:hippocampus, prefrontal cortex |
RGD |
PMID:24076087 PMID:26659122 PMID:37366469 |
RGD:596933360, RGD:596936245, RGD:596933361 |
NCBI chr17:5,560,558...5,875,899
|
|
G |
Per1 |
period circadian regulator 1 |
severity |
ISO |
mRNA:decreased expression:peripheral blood mononuclear cells (human) |
RGD |
PMID:20735373 |
RGD:401976556 |
NCBI chr10:54,299,002...54,313,804
|
|
G |
Per2 |
period circadian regulator 2 |
severity |
ISO |
mRNA:decreased expression:Peripheral blood mononuclear cell (human) |
RGD |
PMID:20735373 |
RGD:401976556 |
NCBI chr 9:99,454,828...99,497,069
|
|
G |
Pomc |
proopiomelanocortin |
|
IEP ISO |
mRNA:increased expression:hypothalamus protein:decreased expression:plasma |
RGD |
PMID:11981131 PMID:11704624 PMID:9406908 PMID:31117084 |
RGD:407424597, RGD:407550224, RGD:407550223, RGD:407431638 |
NCBI chr 6:32,659,137...32,665,175
|
|
G |
Prl |
prolactin |
treatment |
ISO |
|
RGD |
PMID:3816539 |
RGD:401960110 |
NCBI chr17:38,287,355...38,298,234
|
|
G |
Tlr2 |
toll-like receptor 2 |
|
ISO |
mRNA:increased expression:blood, monocyte |
RGD |
PMID:37058088 |
RGD:597538488 |
NCBI chr 2:171,499,189...171,504,831
|
|
|
G |
Aif1 |
allograft inflammatory factor 1 |
|
IEP |
protein:increased expression:cortex, hippocampus (rat) |
RGD |
PMID:18585922 |
RGD:2313030 |
NCBI chr20:3,651,435...3,657,341
|
|
G |
Cirbp |
cold inducible RNA binding protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:24223948 |
|
NCBI chr 7:10,184,515...10,189,623
|
|
|
G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26711020 |
|
NCBI chr12:40,610,244...40,643,220
|
|
G |
Ankk1 |
ankyrin repeat and kinase domain containing 1 |
|
ISO |
DNA:SNP:exon:rs1800497(human) |
RGD |
PMID:18669994 |
RGD:401959336 |
NCBI chr 8:58,676,327...58,685,012
|
|
G |
Drd2 |
dopamine receptor D2 |
|
ISO |
DNA:SNP:cds:957C>T(human) |
RGD |
PMID:18669994 |
RGD:401959336 |
NCBI chr 8:58,605,403...58,669,339
|
|
G |
Foxo4 |
forkhead box O4 |
|
IEP |
protein:increased phosphorylation:small intestine: |
RGD |
PMID:23292333 |
RGD:10402360 |
NCBI chr X:66,385,241...66,392,115
|
|
G |
Gsr |
glutathione-disulfide reductase |
treatment |
IEP |
|
RGD |
PMID:24972622 |
RGD:10401897 |
NCBI chr16:65,185,574...65,228,742
|
|
G |
Hectd4 |
HECT domain E3 ubiquitin protein ligase 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:35713687 |
|
NCBI chr12:40,800,232...40,991,584
|
|
|
G |
Ppa2 |
inorganic pyrophosphatase 2 |
|
ISO |
ClinVar Annotator: match by term: PPA2-related condition | ClinVar Annotator: match by term: Sudden cardiac failure, alcohol-induced |
OMIM ClinVar |
PMID:24033266 PMID:25741868 PMID:27523597 PMID:27523598 PMID:28492532 PMID:30384889 PMID:31705601 PMID:33028643 PMID:34400813 More...
|
|
NCBI chr 2:221,800,791...221,878,079
|
|
|
G |
Bdnf |
brain-derived neurotrophic factor |
sexual_dimorphism |
IEP |
protein:altered expression:brain protein:altered expression:frontal cortex,hippocampus,occipital cortex protein:altered expression:cerebral cortex |
RGD |
PMID:10837897 PMID:18652597 PMID:14604765 |
RGD:401965408, RGD:401976540, RGD:401976539 |
NCBI chr 3:116,619,633...116,670,212
|
|
G |
Cartpt |
CART prepropeptide |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22823101 |
|
NCBI chr 2:32,989,215...32,991,794
|
|
G |
Casp8 |
caspase 8 |
treatment |
IEP |
|
RGD |
PMID:30118883 |
RGD:13782287 |
NCBI chr 9:67,747,109...67,806,699
|
|
G |
Cd4 |
Cd4 molecule |
sexual_dimorphism |
IEP |
associated with Mycobacterium Infections;protein:decreased expression:spleen (rat) protein:increases expression:spleen (rat) |
RGD |
PMID:9744851 PMID:8214423 |
RGD:407446372, RGD:407446376 |
NCBI chr 4:159,355,147...159,381,636
|
|
G |
Crh |
corticotropin releasing hormone |
sexual_dimorphism |
IEP |
mRNA:increased expression:fetus, thymus |
RGD |
PMID:8977428 |
RGD:405878076 |
NCBI chr 2:104,059,184...104,061,048
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
|
IEP |
protein:increased expression:liver |
RGD |
PMID:9731567 |
RGD:405101375 |
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
|
IEP |
protein:increased expression:liver |
RGD |
PMID:9731567 |
RGD:405101375 |
NCBI chr 5:115,009,900...115,012,993
|
|
G |
Ngf |
nerve growth factor |
|
IEP ISO |
protein:altered expression:brain protein:decreased expression:entorhinal cortex protein:increased expression:frontal cortex,cerebellar vermis protein:increased expression:cerebral cortex protein:increased expression:thalamus |
RGD |
PMID:10837897 PMID:10440485 PMID:18652597 PMID:14604765 PMID:21277941 |
RGD:401965408, RGD:401976542, RGD:401976540, RGD:401976539, RGD:401976494 |
NCBI chr 2:192,589,580...192,642,971
|
|
G |
Ngfr |
nerve growth factor receptor |
|
IEP |
protein:decreased expression:brain protein:altered expression:brain |
RGD |
PMID:15188276 PMID:15188277 |
RGD:401976554, RGD:401976555 |
NCBI chr10:81,012,077...81,030,305
|
|
G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
|
ISO |
|
RGD |
PMID:16325017 |
RGD:408345251 |
NCBI chr18:31,522,783...31,644,508
|
|
G |
Ntf3 |
neurotrophin 3 |
|
IEP |
protein:increased expression:hippocampus,cerebellar vermis |
RGD |
PMID:18652597 |
RGD:401976540 |
NCBI chr 4:158,914,984...158,984,453
|
|
G |
Ntrk1 |
neurotrophic receptor tyrosine kinase 1 |
|
IEP |
protein:altered expression:brain protein:decreased expression:brain |
RGD |
PMID:15188276 PMID:15188277 |
RGD:401976554, RGD:401976555 |
NCBI chr 2:175,534,844...175,551,664
|
|
G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
|
IEP |
protein:altered expression:brain |
RGD |
PMID:15188276 PMID:15188277 |
RGD:401976554, RGD:401976555 |
NCBI chr17:5,560,558...5,875,899
|
|
G |
Ntrk3 |
neurotrophic receptor tyrosine kinase 3 |
|
IEP |
protein:altered expression:brain |
RGD |
PMID:15188276 PMID:15188277 |
RGD:401976554, RGD:401976555 |
NCBI chr 1:141,526,192...141,913,575
|
|
G |
Oprk1 |
opioid receptor, kappa 1 |
treatment |
IDA |
|
RGD |
PMID:20962231 |
RGD:401850591 |
NCBI chr 5:18,657,866...18,675,671
|
|
G |
Pomc |
proopiomelanocortin |
sexual_dimorphism |
IEP |
mRNA:decreased expression:fetus, thymus |
RGD |
PMID:8977428 |
RGD:405878076 |
NCBI chr 6:32,659,137...32,665,175
|
|
G |
Tlr2 |
toll-like receptor 2 |
treatment |
ISO |
|
RGD |
PMID:26226164 |
RGD:597538484 |
NCBI chr 2:171,499,189...171,504,831
|
|
G |
Tlr4 |
toll-like receptor 4 |
treatment |
ISO |
|
RGD |
PMID:26226164 |
RGD:597538484 |
NCBI chr 5:85,161,247...85,174,882
|
|
|
G |
Ace |
angiotensin I converting enzyme |
|
ISO |
|
GAD |
PMID:15118671 |
RGD:1331525 |
NCBI chr10:91,410,129...91,430,246
|
|
G |
Agt |
angiotensinogen |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22497828 |
|
NCBI chr19:69,426,540...69,447,017
|
|
G |
Atg3 |
autophagy related 3 |
treatment |
ISO |
|
RGD |
PMID:29039471 |
RGD:407532638 |
NCBI chr11:55,624,914...55,653,249
|
|
G |
Atg7 |
autophagy related 7 |
treatment |
ISO |
|
RGD |
PMID:29039471 |
RGD:407532638 |
NCBI chr 4:149,390,000...149,597,534
|
|
G |
Becn1 |
beclin 1 |
treatment |
ISO |
|
RGD |
PMID:29039471 |
RGD:407532638 |
NCBI chr10:86,731,649...86,747,002
|
|
G |
Nos1 |
nitric oxide synthase 1 |
|
IEP |
protein:decreased expression:skeletal muscle, membrane |
RGD |
PMID:17607508 |
RGD:1642138 |
NCBI chr12:44,276,011...44,456,371
|
|
G |
Pparg |
peroxisome proliferator-activated receptor gamma |
|
IEP |
protein:increased expression:heart myocardium |
RGD |
PMID:18783396 |
RGD:2301868 |
NCBI chr 4:150,095,743...150,221,104
|
|
G |
Rxra |
retinoid X receptor alpha |
|
IEP |
|
RGD |
PMID:19791468 |
RGD:2317465 |
NCBI chr 3:31,387,892...31,474,415
|
|
G |
Slc25a4 |
solute carrier family 25 member 4 |
|
IEP |
mRNA, protein:decreased expression:myocardium |
RGD |
PMID:21169901 |
RGD:9681464 |
NCBI chr16:46,072,935...46,076,730
|
|
|
G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr 3:74,424,620...74,520,646
|
|
G |
Agt |
angiotensinogen |
|
ISO |
mRNA:decreased expression:liver |
RGD |
PMID:17258719 |
RGD:1601135 |
NCBI chr19:69,426,540...69,447,017
|
|
G |
Ahr |
aryl hydrocarbon receptor |
|
ISO |
protein:altered expression:hepatocyte |
RGD |
PMID:34082111 |
RGD:405866379 |
NCBI chr 6:57,961,423...57,998,901
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
|
ISO |
protein:increased expression:liver |
RGD |
PMID:28089901 |
RGD:407987426 |
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Alb |
albumin |
severity |
ISO |
protein:increased expression, modification:urine |
RGD |
PMID:29369844 |
RGD:14694842 |
NCBI chr14:17,891,564...17,907,043
|
|
G |
Atg3 |
autophagy related 3 |
treatment |
ISO |
|
RGD |
PMID:36308627 |
RGD:407532639 |
NCBI chr11:55,624,914...55,653,249
|
|
G |
Atg7 |
autophagy related 7 |
treatment |
ISO |
protein:increased expression:liver |
RGD |
PMID:31090940 PMID:36308627 |
RGD:407445926, RGD:407532639 |
NCBI chr 4:149,390,000...149,597,534
|
|
G |
Becn1 |
beclin 1 |
|
ISO |
protein:increased expression:liver |
RGD |
PMID:31090940 |
RGD:407445926 |
NCBI chr10:86,731,649...86,747,002
|
|
G |
Ccl2 |
C-C motif chemokine ligand 2 |
severity |
ISO |
RNA:increased expression:liver: |
RGD |
PMID:24429361 PMID:21826694 PMID:10446112 |
RGD:14975280, RGD:14995491, RGD:14995467 |
NCBI chr10:67,503,077...67,504,875
|
|
G |
Ccl3 |
C-C motif chemokine ligand 3 |
severity |
ISO |
|
RGD |
PMID:10446112 |
RGD:14995467 |
NCBI chr10:68,948,889...68,950,439
|
|
G |
Ccl5 |
C-C motif chemokine ligand 5 |
treatment |
ISO IEP |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:12586603 PMID:31258651 |
RGD:14995304 |
NCBI chr10:68,820,330...68,824,906
|
|
G |
Col1a1 |
collagen type I alpha 1 chain |
|
ISO |
|
RGD |
PMID:1670041 |
RGD:5688335 |
NCBI chr10:80,380,458...80,397,461
|
|
G |
Cpt1a |
carnitine palmitoyltransferase 1A |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr 1:209,993,881...210,056,329
|
|
G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr 5:24,174,505...24,184,202
|
|
G |
Ddr1 |
discoidin domain receptor tyrosine kinase 1 |
disease_progression severity |
ISO |
mRNA:increased expression:liver (mouse) mRNA:increased expression:liver (human) |
RGD |
PMID:33173221 PMID:33173221 |
RGD:151347691, RGD:151347691 |
NCBI chr20:3,047,269...3,069,277
|
|
G |
Fas |
Fas cell surface death receptor |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr 1:241,212,155...241,245,774
|
|
G |
Fgf19 |
fibroblast growth factor 19 |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr 1:209,485,813...209,490,267
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
severity |
ISO |
protein:increased expression:hepatocyte |
RGD |
PMID:1347281 |
RGD:14402038 |
NCBI chr 8:27,829,688...27,841,618
|
|
G |
Il13 |
interleukin 13 |
|
IEP |
mRNA:increased expression:liver |
RGD |
PMID:16698589 |
RGD:1581860 |
NCBI chr10:38,290,926...38,293,483
|
|
G |
Il18 |
interleukin 18 |
severity |
ISO |
associated alcoholic liver cirrhosis; protein:increased expression:plasma: |
RGD |
PMID:15566508 |
RGD:14696666 |
NCBI chr 8:59,802,072...59,829,275
|
|
G |
Mir155 |
microRNA 155 |
ameliorates |
IEP ISO |
RNA:increased expression:liver |
RGD |
PMID:32317960 PMID:31090940 |
RGD:151347420, RGD:407445926 |
NCBI chr11:37,261,114...37,261,178
|
|
G |
Mtor |
mechanistic target of rapamycin kinase |
|
ISO |
protein:decreased expression:liver |
RGD |
PMID:31090940 |
RGD:407445926 |
NCBI chr 5:164,167,985...164,277,438
|
|
G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr 2:226,689,745...226,805,897
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr 6:78,593,844...78,597,307
|
|
G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr10:44,826,299...44,853,373
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
|
ISO |
protein:altered expression:hepatocyte |
RGD |
PMID:34082111 |
RGD:405866379 |
NCBI chr19:52,205,374...52,220,267
|
|
G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr 5:145,779,294...145,782,609
|
|
G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr 7:25,733,471...25,829,440
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr 7:118,712,261...118,780,723
|
|
G |
Sell |
selectin L |
treatment |
ISO IEP |
mRNA:increased expression:liver |
RGD |
PMID:10782906 PMID:9835285 |
RGD:597015742, RGD:597015743 |
NCBI chr13:78,950,100...78,969,604
|
|
G |
Slc10a1 |
solute carrier family 10 member 1 |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr 6:100,613,045...100,626,670
|
|
G |
Socs1 |
suppressor of cytokine signaling 1 |
|
IEP |
mRNA:decreased expression:liver |
RGD |
PMID:32317960 |
RGD:151347420 |
NCBI chr10:5,389,574...5,391,265
|
|
G |
Sqstm1 |
sequestosome 1 |
treatment |
ISO |
protein:increased expression:liver |
RGD |
PMID:31090940 PMID:36308627 |
RGD:407445926, RGD:407532639 |
NCBI chr10:35,026,598...35,037,750
|
|
G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
treatment |
IEP |
|
RGD |
PMID:27939985 |
RGD:15036816 |
NCBI chr10:45,507,152...45,529,164
|
|
G |
Sts |
steroid sulfatase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26220752 |
|
NCBI chr X:46,102,524...46,110,868
|
|
G |
Sult1e1 |
sulfotransferase family 1E member 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26220752 |
|
NCBI chr14:20,422,324...20,439,562
|
|
G |
Tnf |
tumor necrosis factor |
treatment |
ISO IEP |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:12586603 PMID:27939985 |
RGD:15036816 |
NCBI chr20:3,626,685...3,629,303
|
|
|
G |
Arc |
activity-regulated cytoskeleton-associated protein |
disease_progression |
ISO |
mRNA:altered expression:brain (mouse) |
RGD |
PMID:26708208 |
RGD:401853772 |
NCBI chr 7:108,444,959...108,448,413
|
|
G |
Bdnf |
brain-derived neurotrophic factor |
|
ISO |
mRNA,protein:decreased expression:cerebellum |
RGD |
PMID:19861148 |
RGD:401965398 |
NCBI chr 3:116,619,633...116,670,212
|
|
G |
Drd2 |
dopamine receptor D2 |
treatment |
IDA |
|
RGD |
PMID:28300818 |
RGD:13506954 |
NCBI chr 8:58,605,403...58,669,339
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
|
IEP |
protein:altered expression:brain mRNA:decreased expression:adrenal gland |
RGD |
PMID:26727528 PMID:12351928 |
RGD:405101372, RGD:405255666 |
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Gdnf |
glial cell derived neurotrophic factor |
|
ISO |
mRNA:decreased expression:basal nucleus |
RGD |
PMID:24061482 |
RGD:405850213 |
NCBI chr 2:58,621,327...58,647,242
|
|
G |
Ifng |
interferon gamma |
treatment |
ISO |
|
RGD |
PMID:9514301 |
RGD:10755766 |
NCBI chr 7:55,789,180...55,793,216
|
|
G |
Ngf |
nerve growth factor |
|
ISO |
mRNA,protein:increased expression:cerebellum protein:increased expression:plasma |
RGD |
PMID:19861148 PMID:18639986 |
RGD:401965398, RGD:401965411 |
NCBI chr 2:192,589,580...192,642,971
|
|
G |
Nps |
neuropeptide S |
|
IDA |
|
RGD |
PMID:19860802 |
RGD:9831199 |
NCBI chr 1:199,505,772...199,510,915
|
|
G |
Npsr1 |
neuropeptide S receptor 1 |
|
IEP |
mRNA:increased expression:brain |
RGD |
PMID:19860802 |
RGD:9831199 |
NCBI chr 8:30,882,830...31,107,425
|
|
G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
sexual_dimorphism |
ISO |
DNA:SNP: :rs244465 |
RGD |
PMID:20731635 |
RGD:408345194 |
NCBI chr18:31,522,783...31,644,508
|
|
G |
Ntrk1 |
neurotrophic receptor tyrosine kinase 1 |
|
ISO |
mRNA,protein:increased expression:cerebellum |
RGD |
PMID:19861148 |
RGD:401965398 |
NCBI chr 2:175,534,844...175,551,664
|
|
G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
|
ISO |
mRNA:increased expression:basal nucleus, cerebral cortex |
RGD |
PMID:24061482 |
RGD:405850213 |
NCBI chr17:5,560,558...5,875,899
|
|
G |
Per2 |
period circadian regulator 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15608650 |
|
NCBI chr 9:99,454,828...99,497,069
|
|
|
G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
susceptibility |
ISO |
DNA:missense mutation:cds:p.E504K (human) DNA:missense mutation:cds: (rs671) (human) associated with alcohol dependence;DNA:missense mutation:exon 12:p.E487K (human) |
RGD |
PMID:29779728 PMID:23550892 PMID:11051375 |
RGD:14696777, RGD:15042864, RGD:15042858 |
NCBI chr12:40,610,244...40,643,220
|
|
G |
Bcl2 |
BCL2, apoptosis regulator |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23274713 |
|
NCBI chr13:23,204,464...23,366,900
|
|
G |
C3 |
complement C3 |
|
ISO |
|
RGD |
PMID:9176087 |
RGD:408418722 |
NCBI chr 9:2,174,412...2,201,339
|
|
G |
Cat |
catalase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23274713 |
|
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Cnp |
2',3'-cyclic nucleotide 3' phosphodiesterase |
|
ISO |
protein:decreased expression:brain |
RGD |
PMID:16205370 |
RGD:6483345 |
NCBI chr10:86,011,504...86,018,063
|
|
G |
Col3a1 |
collagen type III alpha 1 chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23274713 |
|
NCBI chr 9:54,866,646...54,902,578
|
|
G |
Crp |
C-reactive protein |
severity |
ISO |
|
RGD |
PMID:22441510 |
RGD:6482305 |
NCBI chr13:87,694,062...87,695,978
|
|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:20843640 PMID:29404441 |
RGD:14700873 |
NCBI chr 1:205,269,967...205,280,365
|
|
G |
Ddr1 |
discoidin domain receptor tyrosine kinase 1 |
severity |
ISO |
mRNA:increased expression:liver (human) |
RGD |
PMID:33173221 |
RGD:151347691 |
NCBI chr20:3,047,269...3,069,277
|
|
G |
Ddr2 |
discoidin domain receptor tyrosine kinase 2 |
disease_progression ameliorates |
IEP IMP |
|
RGD |
PMID:21199726 PMID:23409069 |
RGD:150429766, RGD:150517731 |
NCBI chr13:84,726,412...84,851,032
|
|
G |
Fabp2 |
fatty acid binding protein 2 |
onset |
ISO |
DNA:polymorphism:CDS:amino acid A54T, homozygosity of the T allele associated with later onset |
RGD |
PMID:16289894 PMID:16289894 |
RGD:1578455, RGD:1578455 |
NCBI chr 2:211,040,032...211,044,089
|
|
G |
Gabrg2 |
gamma-aminobutyric acid type A receptor subunit gamma 2 |
susceptibility |
ISO |
DNA:SNP:intron 8:84435G>A (human) |
RGD |
PMID:19428381 |
RGD:402463950 |
NCBI chr10:26,876,926...26,965,523
|
|
G |
Il18bp |
interleukin 18 binding protein |
|
ISO |
protein:increased expression:plasma: |
RGD |
PMID:15566508 |
RGD:14696666 |
NCBI chr 1:156,372,923...156,374,963
|
|
G |
Il6 |
interleukin 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:23274713 PMID:21236309 |
RGD:597538491 |
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Jak2 |
Janus kinase 2 |
|
ISO |
mRNA, protein:increased expression, increased tyrosine phosphorylation:liver |
RGD |
PMID:24619965 |
RGD:10403061 |
NCBI chr 1:236,408,905...236,468,769
|
|
G |
Lep |
leptin |
|
IDA |
DNA:hypomethylation:promoter (human) |
RGD |
PMID:29912265 |
RGD:21201248 |
NCBI chr 4:58,626,529...58,640,663
|
|
G |
Mboat7 |
membrane bound O-acyltransferase domain containing 7 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26482880 |
|
NCBI chr 1:74,440,618...74,454,896
|
|
G |
Mir122 |
microRNA 122 |
|
ISO |
miRNA:decreased expression:liver |
RGD |
PMID:28987423 |
RGD:14401600 |
NCBI chr18:61,028,817...61,028,901
|
|
G |
Mir141 |
microRNA 141 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28545106 |
|
NCBI chr 4:157,523,239...157,523,332
|
|
G |
Mir17 |
microRNA 17 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28545106 |
|
NCBI chr15:92,180,629...92,180,712
|
|
G |
Mir193b |
microRNA 193b |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28545106 |
|
NCBI chr10:1,317,742...1,317,824
|
|
G |
Mir423 |
microRNA 423 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28545106 |
|
NCBI chr10:61,914,142...61,914,220
|
|
G |
Mir484 |
microRNA 484 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28545106 |
|
NCBI chr10:887,684...887,760
|
|
G |
Mir532 |
microRNA 532 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28545106 |
|
NCBI chr X:15,247,315...15,247,393
|
|
G |
Mir93 |
microRNA 93 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28545106 |
|
NCBI chr12:17,043,135...17,043,221
|
|
G |
Mmp13 |
matrix metallopeptidase 13 |
|
IEP |
|
RGD |
PMID:16286264 |
RGD:10043176 |
NCBI chr 8:4,497,960...4,508,239
|
|
G |
Mmp2 |
matrix metallopeptidase 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23274713 |
|
NCBI chr19:30,327,643...30,355,856
|
|
G |
Mpo |
myeloperoxidase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19731237 PMID:23274713 |
|
NCBI chr10:73,092,124...73,102,057
|
|
G |
Mthfr |
methylenetetrahydrofolate reductase |
susceptibility |
ISO |
DNA:SNP: :677C>T(human) |
RGD |
PMID:25987440 |
RGD:14696749 |
NCBI chr 5:163,748,346...163,768,141
|
|
G |
Nr1d1 |
nuclear receptor subfamily 1, group D, member 1 |
|
ISO |
|
RGD |
PMID:24497272 |
RGD:10448995 |
NCBI chr10:84,224,599...84,231,812
|
|
G |
Plau |
plasminogen activator, urokinase |
|
IDA |
|
RGD |
PMID:19615318 |
RGD:7241800 |
NCBI chr15:3,505,485...3,511,987
|
|
G |
Pnpla3 |
patatin-like phospholipase domain containing 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19946271 PMID:26482880 |
|
NCBI chr 7:115,293,538...115,314,077
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23274713 |
|
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Serpine1 |
serpin family E member 1 |
susceptibility |
ISO |
DNA:polymorphism:promoter: |
RGD |
PMID:25987440 |
RGD:14696749 |
NCBI chr12:25,237,977...25,248,356
|
|
G |
Serpinf1 |
serpin family F member 1 |
|
ISO |
protein:increased expression:serum (human) |
RGD |
PMID:27748324 |
RGD:27226704 |
NCBI chr10:60,250,198...60,262,593
|
|
G |
Smad3 |
SMAD family member 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23274713 |
|
NCBI chr 8:64,126,829...64,236,960
|
|
G |
Sod2 |
superoxide dismutase 2 |
susceptibility |
ISO |
CTD Direct Evidence: marker/mechanism DNA:SNP: : 47T>C(human) |
CTD RGD |
PMID:19731237 PMID:26873981 |
RGD:11060603 |
NCBI chr 1:50,043,323...50,050,168
|
|
G |
Tg |
thyroglobulin |
|
ISO |
|
RGD |
PMID:6883738 |
RGD:401976502 |
NCBI chr 7:98,418,293...98,603,210
|
|
G |
Tgfb1 |
transforming growth factor, beta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23274713 |
|
NCBI chr 1:90,324,312...90,340,627
|
|
G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23274713 |
|
NCBI chr X:3,766,509...3,772,578
|
|
G |
Tlr2 |
toll-like receptor 2 |
|
ISO |
protein:increased expression:blood, neutrophil |
RGD |
PMID:18433921 |
RGD:5130706 |
NCBI chr 2:171,499,189...171,504,831
|
|
G |
Tlr4 |
toll-like receptor 4 |
treatment |
ISO |
|
RGD |
PMID:18433921 |
RGD:5130706 |
NCBI chr 5:85,161,247...85,174,882
|
|
G |
Tlr9 |
toll-like receptor 9 |
|
ISO |
protein:increased expression:blood, neutrophil |
RGD |
PMID:18433921 |
RGD:5130706 |
NCBI chr 8:115,743,407...115,747,523
|
|
G |
Tm6sf2 |
transmembrane 6 superfamily member 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:26482880 |
|
NCBI chr16:19,344,218...19,351,431
|
|
G |
Tnf |
tumor necrosis factor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:23274713 |
|
NCBI chr20:3,626,685...3,629,303
|
|
|
G |
Ace |
angiotensin I converting enzyme |
severity treatment |
ISO |
protein:increased activity:serum (human) |
RGD |
PMID:3028446 PMID:28691216 |
RGD:19165343, RGD:40400719 |
NCBI chr10:91,410,129...91,430,246
|
|
G |
Adipor2 |
adiponectin receptor 2 |
treatment |
IEP |
|
RGD |
PMID:24797033 |
RGD:25824940 |
NCBI chr 4:152,524,604...152,588,848
|
|
G |
Ager |
advanced glycosylation end product-specific receptor |
|
ISO |
mRNA, protein:increased expression:serum |
RGD |
PMID:36502724 |
RGD:597538595 |
NCBI chr20:4,152,758...4,155,956
|
|
G |
Ahr |
aryl hydrocarbon receptor |
exacerbates ameliorates |
ISO |
|
RGD |
PMID:34454169 PMID:36871955 |
RGD:405866377, RGD:405866378 |
NCBI chr 6:57,961,423...57,998,901
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
treatment |
ISO |
|
RGD |
PMID:35926779 |
RGD:408345226 |
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
susceptibility severity |
ISO |
DNA:missense mutation:cds, exon 12:p.E487K (human) DNA:polymorphism:exon 12: (human) DNA:deletion:cds: (mouse) |
RGD |
PMID:1916152 PMID:12198368 PMID:26173414 PMID:3189338 |
RGD:14696699, RGD:14981580, RGD:11076022, RGD:14696790 |
NCBI chr12:40,610,244...40,643,220
|
|
G |
Angpt2 |
angiopoietin 2 |
severity |
ISO |
|
RGD |
PMID:24959006 |
RGD:15014784 |
NCBI chr16:71,088,364...71,138,805
|
|
G |
Atg7 |
autophagy related 7 |
|
ISO |
protein:increased expression:liver |
RGD |
PMID:31090940 |
RGD:407445926 |
NCBI chr 4:149,390,000...149,597,534
|
|
G |
Becn1 |
beclin 1 |
|
ISO |
protein:increased expression:liver |
RGD |
PMID:31090940 |
RGD:407445926 |
NCBI chr10:86,731,649...86,747,002
|
|
G |
Bhmt |
betaine-homocysteine S-methyltransferase |
|
IEP |
protein:increased expression:cytosol |
RGD |
PMID:25684186 |
RGD:408418736 |
NCBI chr 2:26,594,852...26,614,429
|
|
G |
C6 |
complement C6 |
resistance |
IAGP |
|
RGD |
PMID:15351314 |
RGD:1600673 |
NCBI chr 2:53,846,028...53,921,279
|
|
G |
Car3 |
carbonic anhydrase 3 |
|
IEP |
protein:decreased expression:cytosol |
RGD |
PMID:25684186 |
RGD:408418736 |
NCBI chr 2:88,491,666...88,501,299
|
|
G |
Cat |
catalase |
treatment |
IEP |
|
RGD |
PMID:8370342 PMID:28898587 |
RGD:405255646, RGD:405255658 |
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Cav1 |
caveolin 1 |
treatment |
IEP |
|
RGD |
PMID:23764359 |
RGD:8662277 |
NCBI chr 4:46,606,538...46,639,616
|
|
G |
Cd27 |
CD27 molecule |
|
IEP |
|
RGD |
PMID:16698589 |
RGD:1581860 |
NCBI chr 4:158,030,700...158,035,862
|
|
G |
Cd59b |
CD59b molecule |
|
IEP |
protein:decreased expression:liver |
RGD |
PMID:12483994 |
RGD:1600486 |
NCBI chr 3:110,914,008...110,932,489
|
|
G |
Cldn1 |
claudin 1 |
treatment |
IEP |
|
RGD |
PMID:31116255 |
RGD:407424600 |
NCBI chr11:87,926,376...87,941,533
|
|
G |
Cps1 |
carbamoyl-phosphate synthase 1 |
|
IEP |
protein:increased expression:cytosol |
RGD |
PMID:25684186 |
RGD:408418736 |
NCBI chr 9:76,063,863...76,186,739
|
|
G |
Ctla4 |
cytotoxic T-lymphocyte-associated protein 4 |
susceptibility |
ISO |
DNA:SNP::-318 T>C(rs5742909)(human) |
RGD |
PMID:15208156 |
RGD:14398728 |
NCBI chr 9:69,812,859...69,819,959
|
|
G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
|
IEP |
mRNA:increased expression:liver |
RGD |
PMID:10498645 |
RGD:5135271 |
NCBI chr14:17,477,542...17,479,321
|
|
G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
|
IEP |
mRNA:increased expression:liver |
RGD |
PMID:10498645 |
RGD:5135271 |
NCBI chr14:17,465,210...17,467,255
|
|
G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
|
IEP |
mRNA:increased expression:liver |
RGD |
PMID:10498645 |
RGD:5135271 |
NCBI chr14:17,310,790...17,312,250
|
|
G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
treatment |
ISO IEP |
|
RGD |
PMID:29401608 PMID:9927612 PMID:30192013 PMID:25592162 PMID:29902864 |
RGD:14700887, RGD:405650696, RGD:14700906, RGD:14700894, RGD:14700893 |
NCBI chr 1:205,269,967...205,280,365
|
|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
|
ISO |
|
RGD |
PMID:9927612 |
RGD:405650696 |
NCBI chr12:14,321,771...14,343,886
|
|
G |
Egfr |
epidermal growth factor receptor |
|
ISO |
|
RGD |
PMID:30502657 |
RGD:38599215 |
NCBI chr14:95,378,626...95,551,358
|
|
G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
|
IDA |
|
RGD |
PMID:21059295 |
RGD:10395351 |
NCBI chr 6:103,405,880...103,430,549
|
|
G |
Fas |
Fas cell surface death receptor |
|
ISO |
protein:increased expression:lymphocyte: |
RGD |
PMID:26429926 |
RGD:14700711 |
NCBI chr 1:241,212,155...241,245,774
|
|
G |
Fkbp5 |
FKBP prolyl isomerase 5 |
ameliorates |
ISO |
mRNA,protein:incrased expression:liver (human) |
RGD |
PMID:33710653 PMID:33710653 |
RGD:401976495, RGD:401976495 |
NCBI chr20:6,458,931...6,577,227
|
|
G |
Gdnf |
glial cell derived neurotrophic factor |
|
ISO |
protein:increased expression:serum mRNA,protein:increased expression:liver |
RGD |
PMID:35338490 PMID:35338490 |
RGD:405849393, RGD:405849393 |
NCBI chr 2:58,621,327...58,647,242
|
|
G |
Gstm1 |
glutathione S-transferase mu 1 |
|
ISO |
|
RGD |
PMID:15932176 PMID:26937962 |
RGD:14700973, RGD:11060494 |
NCBI chr 2:198,338,005...198,346,007
|
|
G |
Gstt1 |
glutathione S-transferase theta 1 |
|
ISO |
|
RGD |
PMID:15932176 PMID:26937962 |
RGD:14700973, RGD:11060494 |
NCBI chr20:12,856,068...12,873,020
|
|
G |
Hfe |
homeostatic iron regulator |
|
IEP |
mRNA:increased expression:liver, Kupffer cell (rat) |
RGD |
PMID:18599584 |
RGD:8694397 |
NCBI chr17:41,841,302...41,849,359
|
|
G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
|
IEP |
mRNA:increased expression:liver (rat) |
RGD |
PMID:17085342 |
RGD:9068897 |
NCBI chr 6:98,357,788...98,405,068
|
|
G |
Igf2 |
insulin-like growth factor 2 |
|
IEP |
mRNA:increased expression:liver |
RGD |
PMID:18505416 |
RGD:5510002 |
NCBI chr 1:197,814,409...197,831,802
|
|
G |
Il1b |
interleukin 1 beta |
|
IEP |
protein:increased expression:serum (rat) |
RGD |
PMID:23009062 |
RGD:7204488 |
NCBI chr 3:137,030,200...137,036,581
|
|
G |
Il6 |
interleukin 6 |
treatment |
IEP |
|
RGD |
PMID:31116255 |
RGD:407424600 |
NCBI chr 4:5,889,999...5,894,575
|
|
G |
Keap1 |
Kelch-like ECH-associated protein 1 |
|
ISO |
mRNA:decreased expression:liver (human) |
RGD |
PMID:22459801 |
RGD:6892954 |
NCBI chr 8:19,768,375...19,777,862
|
|
G |
Lpl |
lipoprotein lipase |
treatment |
IEP |
|
RGD |
PMID:28442378 |
RGD:13794376 |
NCBI chr16:25,596,205...25,621,928
|
|
G |
Mif |
macrophage migration inhibitory factor |
|
IEP |
protein:increased expression:liver |
RGD |
PMID:11798463 |
RGD:1642007 |
NCBI chr20:12,790,919...12,791,784
|
|
G |
Mir122 |
microRNA 122 |
|
ISO |
miRNA:decreased expression:hepatocyte |
RGD |
PMID:28987423 |
RGD:14401600 |
NCBI chr18:61,028,817...61,028,901
|
|
G |
Mir155 |
microRNA 155 |
ameliorates |
ISO |
RNA:increased expression:liver |
RGD |
PMID:28492308 PMID:31090940 PMID:31090940 |
RGD:25314298, RGD:407445926, RGD:407445926 |
NCBI chr11:37,261,114...37,261,178
|
|
G |
Mir223 |
microRNA 223 |
severity |
ISO |
|
RGD |
PMID:27679493 |
RGD:21408575 |
NCBI chr X:61,141,887...61,141,996
|
|
G |
Mmp9 |
matrix metallopeptidase 9 |
|
IEP |
protein:increased expression:liver |
RGD |
PMID:17374579 |
RGD:1642042 |
NCBI chr 3:174,103,474...174,111,434
|
|
G |
Mtor |
mechanistic target of rapamycin kinase |
|
ISO |
protein:decreased expression:liver |
RGD |
PMID:31090940 PMID:31090940 |
RGD:407445926, RGD:407445926 |
NCBI chr 5:164,167,985...164,277,438
|
|
G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
disease_progression severity |
ISO |
mRNA:increased expression:liver |
RGD |
PMID:26576483 PMID:26576483 |
RGD:14695016, RGD:14695016 |
NCBI chr 7:95,483,105...95,488,031
|
|
G |
Nedd8 |
NEDD8 ubiquitin like modifier |
|
ISO |
|
RGD |
PMID:12533840 |
RGD:1549458 |
NCBI chr15:33,123,505...33,135,522
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
treatment severity |
ISO |
DNA:SNP:promoter:rs35652124(human) |
RGD |
PMID:31906014 PMID:31340446 |
RGD:21201307, RGD:21201311 |
NCBI chr 3:81,001,529...81,031,165
|
|
G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
ameliorates |
ISO |
|
RGD |
PMID:34082111 |
RGD:405866379 |
NCBI chr19:52,205,374...52,220,267
|
|
G |
Otc |
ornithine transcarbamylase |
|
IEP |
protein:increased expression:serum (rat) |
RGD |
PMID:19101528 |
RGD:4144059 |
NCBI chr X:15,126,358...15,202,473
|
|
G |
Plaur |
plasminogen activator, urokinase receptor |
|
ISO |
protein:increased expression:serum |
RGD |
PMID:22098627 |
RGD:6484116 |
NCBI chr 1:89,181,363...89,196,308
|
|
G |
Pnpla3 |
patatin-like phospholipase domain containing 3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19946271 |
|
NCBI chr 7:115,293,538...115,314,077
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
severity |
ISO |
DNA:knockout::increased severity in knockouts (mouse) |
RGD |
PMID:15382117 |
RGD:5683636 |
NCBI chr 7:118,712,261...118,780,723
|
|
G |
Ppard |
peroxisome proliferator-activated receptor delta |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:27765815 |
|
NCBI chr20:6,300,527...6,365,707
|
|
G |
Psmd14 |
proteasome 26S subunit, non-ATPase 14 |
|
IEP |
protein:decreased expression:liver, cytosolic proteasome complex (rat) |
RGD |
PMID:19609968 |
RGD:9480236 |
NCBI chr 3:46,254,338...46,347,076
|
|
G |
Rbp4 |
retinol binding protein 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16762690 |
|
NCBI chr 1:235,893,917...235,901,315
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
|
ISO |
protein:increased phosphorylation:liver |
RGD |
PMID:35338490 |
RGD:405849393 |
NCBI chr 1:212,354,336...212,364,815
|
|
G |
Slc39a13 |
solute carrier family 39 member 13 |
|
IEP |
protein:increased expression:liver, endoplasmic reticulum (rat) |
RGD |
PMID:25767260 |
RGD:11553884 |
NCBI chr 3:77,039,411...77,047,528
|
|
G |
Sod1 |
superoxide dismutase 1 |
treatment |
ISO |
human gene in a rat model |
RGD |
PMID:11266387 |
RGD:9587792 |
NCBI chr11:42,942,742...42,948,399
|
|
G |
Sod2 |
superoxide dismutase 2 |
treatment |
ISO |
|
RGD |
PMID:32236798 |
RGD:27095880 |
NCBI chr 1:50,043,323...50,050,168
|
|
G |
Spp1 |
secreted phosphoprotein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18703563 |
|
NCBI chr14:5,613,569...5,620,695
|
|
G |
Sqstm1 |
sequestosome 1 |
|
ISO |
protein:increased expression:liver |
RGD |
PMID:31090940 PMID:31090940 |
RGD:407445926, RGD:407445926 |
NCBI chr10:35,026,598...35,037,750
|
|
G |
Tbxas1 |
thromboxane A synthase 1 |
|
IEP |
mRNA,protein:increased expression:liver, Kupffer cell: |
RGD |
PMID:9262373 |
RGD:11059607 |
NCBI chr 4:67,664,963...67,837,096
|
|
G |
Tert |
telomerase reverse transcriptase |
|
ISO |
mRNA,protein,activity:increased expression, increased activity:kupffer cell: |
RGD |
PMID:26725521 |
RGD:11574970 |
NCBI chr 1:29,637,213...29,659,561
|
|
G |
Tlr2 |
toll-like receptor 2 |
treatment |
ISO |
mRNA:increased expression:liver |
RGD |
PMID:16628628 PMID:30353422 |
RGD:597538497, RGD:597538498 |
NCBI chr 2:171,499,189...171,504,831
|
|
G |
Tlr3 |
toll-like receptor 3 |
treatment |
ISO |
|
RGD |
PMID:23023014 PMID:30870678 |
RGD:21079426, RGD:21079436 |
NCBI chr16:53,554,916...53,572,321
|
|
G |
Tlr4 |
toll-like receptor 4 |
|
ISO |
mRNA:increased expression:liver |
RGD |
PMID:16628628 |
RGD:597538497 |
NCBI chr 5:85,161,247...85,174,882
|
|
G |
Tnf |
tumor necrosis factor |
treatment |
IMP IEP |
mRNA:increased expression:liver (rat) |
RGD |
PMID:9397994 PMID:31116255 PMID:7556590 PMID:15670576 |
RGD:14398736, RGD:407424600, RGD:14995472, RGD:14995456 |
NCBI chr20:3,626,685...3,629,303
|
|
G |
Uchl5 |
ubiquitin C-terminal hydrolase L5 |
|
IEP |
protein:decreased expression:liver, cytosolic proteasome complex |
RGD |
PMID:19609968 |
RGD:9480236 |
NCBI chr13:58,070,947...58,106,825
|
|
G |
Vegfa |
vascular endothelial growth factor A |
|
ISO |
protein:increased expression:plasma |
RGD |
PMID:24959006 |
RGD:15014784 |
NCBI chr 9:22,452,854...22,468,194
|
|
|
G |
Igf1 |
insulin-like growth factor 1 |
|
IEP |
|
RGD |
PMID:23016131 |
RGD:10402569 |
NCBI chr 7:24,169,608...24,249,446
|
|
G |
Igf1r |
insulin-like growth factor 1 receptor |
|
IEP |
|
RGD |
PMID:23016131 |
RGD:10402569 |
NCBI chr 1:130,959,787...131,248,664
|
|
G |
Igf2 |
insulin-like growth factor 2 |
|
IEP |
|
RGD |
PMID:23016131 |
RGD:10402569 |
NCBI chr 1:197,814,409...197,831,802
|
|
G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
treatment |
IMP |
|
RGD |
PMID:18093169 |
RGD:408345248 |
NCBI chr18:31,522,783...31,644,508
|
|
|
G |
Car2 |
carbonic anhydrase 2 |
|
ISO |
|
RGD |
PMID:15831920 |
RGD:408425973 |
NCBI chr 2:88,462,883...88,478,012
|
|
G |
Cck |
cholecystokinin |
disease_progression |
ISO |
protein:decreased expression:blood plasma (human) |
RGD |
PMID:11185710 |
RGD:407419866 |
NCBI chr 8:121,153,499...121,160,194
|
|
G |
Cftr |
CF transmembrane conductance regulator |
|
ISO |
DNA:missense mutations: :p.L1156F, Q1352H (human) |
RGD |
PMID:26089335 |
RGD:11566036 |
NCBI chr 4:47,422,084...47,694,646
|
|
G |
Pthlh |
parathyroid hormone-like hormone |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:22280800 |
|
NCBI chr 4:180,188,792...180,199,847
|
|
G |
Ugt1a7c |
UDP glucuronosyltransferase 1 family, polypeptide A7C |
|
ISO |
DNA:polymorphisms: :p.N129K, p.R131K, p.W208R (human) |
RGD |
PMID:12806614 |
RGD:2317503 |
NCBI chr 9:88,739,577...88,808,465
|
|
|
G |
Htr2a |
5-hydroxytryptamine receptor 2A |
|
ISO |
DNA:SNP:promoter:-1438G>A |
RGD |
PMID:11842624 |
RGD:401900738 |
NCBI chr15:56,360,647...56,428,703
|
|
|
G |
Ache |
acetylcholinesterase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16470869 |
|
NCBI chr12:25,042,882...25,050,608
|
|
G |
Acsl6 |
acyl-CoA synthetase long-chain family member 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr10:38,439,914...38,501,182
|
|
G |
Adora2a |
adenosine A2a receptor |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20799992 |
|
NCBI chr20:13,315,848...13,333,386
|
|
G |
Ak5 |
adenylate kinase 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr 2:244,057,240...244,241,372
|
|
G |
Akt1 |
AKT serine/threonine kinase 1 |
no_association susceptibility |
ISO |
CTD Direct Evidence: marker/mechanism DNA:SNPs:introns: (rs2494743, 2498794) DNA:SNP:intron: (rs3730358) |
CTD RGD |
PMID:15982448 PMID:31654273 PMID:15982448 |
RGD:407419880, RGD:407419878 |
NCBI chr 6:137,534,810...137,555,131
|
|
G |
Aoah |
acyloxyacyl hydrolase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr17:48,503,812...48,745,161
|
|
G |
Arc |
activity-regulated cytoskeleton-associated protein |
disease_progression |
ISO |
mRNA:increased expression:brain (mouse) |
RGD |
PMID:25959066 |
RGD:401938592 |
NCBI chr 7:108,444,959...108,448,413
|
|
G |
Arrb2 |
arrestin, beta 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17233643 |
|
NCBI chr10:55,645,539...55,653,485
|
|
G |
Astn2 |
astrotactin 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr 5:78,758,142...79,744,021
|
|
G |
Bdnf |
brain-derived neurotrophic factor |
|
ISO IEP |
CTD Direct Evidence: marker/mechanism protein:increased expression:frontal cortex, striatum protein:increased expression:nucleus accumbens, ventral tegmental area mRNA:increased expression:nucleus accumbens, dorsal striatum protein:decreased expression:hippocampus |
CTD RGD |
PMID:20736000 PMID:31693929 PMID:37904065 PMID:33961872 PMID:24407463 |
RGD:597015747, RGD:596938173, RGD:596936246, RGD:401976437 |
NCBI chr 3:116,619,633...116,670,212
|
|
G |
Cat |
catalase |
treatment |
IEP |
|
RGD |
PMID:24445072 |
RGD:405255657 |
NCBI chr 3:110,297,340...110,329,526
|
|
G |
Cchcr1 |
coiled-coil alpha-helical rod protein 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr20:3,210,383...3,223,187
|
|
G |
Cd4 |
Cd4 molecule |
|
IEP |
protein:decreased expression:spleen (rat) |
RGD |
PMID:25678251 |
RGD:407446373 |
NCBI chr 4:159,355,147...159,381,636
|
|
G |
Cd55 |
CD55 molecule (Cromer blood group) |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr13:44,409,574...44,438,913
|
|
G |
Cd8a |
CD8 subunit alpha |
|
IEP |
protein:increased expression:spleen (rat) |
RGD |
PMID:25678251 |
RGD:407446373 |
NCBI chr 4:104,924,116...104,928,353
|
|
G |
Cdh13 |
cadherin 13 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr19:46,349,562...47,387,462
|
|
G |
Cdk5 |
cyclin-dependent kinase 5 |
|
ISO |
protein:increased expression:ventral tegmental area, nucleus accumbens (mouse) |
RGD |
PMID:28782589 |
RGD:401900303 |
NCBI chr 4:11,647,098...11,651,606
|
|
G |
Cfh |
complement factor H |
|
ISO IEP |
protein:increased expression:serum: protein:increased expression:serum, hippocampus: |
RGD |
PMID:22871478 PMID:22871478 |
RGD:7364944, RGD:7364944 |
NCBI chr13:51,512,376...51,613,829
|
|
G |
Col28a1 |
collagen type XXVIII alpha 1 chain |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr 4:36,069,980...36,223,128
|
|
G |
Comt |
catechol-O-methyltransferase |
susceptibility |
ISO |
CTD Direct Evidence: marker/mechanism DNA:SNP:cd: p.V158M (human) DNA:SNPs,haplotypes:exon,3'utr: (rs4680, rs165599) (human) ClinVar Annotator: match by term: methamphetamine use disorder |
CTD ClinVar RGD |
PMID:15274053 PMID:25741868 PMID:33544778 PMID:21934638 PMID:17187009 PMID:15274053 More...
|
RGD:401959602, RGD:401940147, RGD:401940150, RGD:401940124 |
NCBI chr11:96,072,371...96,091,956
|
|
G |
Creb1 |
cAMP responsive element binding protein 1 |
treatment |
ISO IEP |
protein:increases activity:ventral tegmental area, nucleus accumbens (mouse) mRNA:decreased expression:nucleus accumbens protein:increased expression, increased phosphorylation:nucleus accumbens, ventral tegmental area |
RGD |
PMID:28782589 PMID:33961872 PMID:31900897 |
RGD:401900303, RGD:596936246, RGD:401938636 |
NCBI chr 9:73,397,333...73,466,339
|
|
G |
Csmd1 |
CUB and Sushi multiple domains 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr16:72,218,189...73,818,380
|
|
G |
Cubn |
cubilin |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr17:76,385,046...76,593,133
|
|
G |
Cyp2d4 |
cytochrome P450, family 2, subfamily d, polypeptide 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18280655 |
|
NCBI chr 7:115,762,662...115,771,832
|
|
G |
Dcstamp |
dendrocyte expressed seven transmembrane protein |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr 7:70,807,455...70,822,067
|
|
G |
Drd1 |
dopamine receptor D1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18363855 PMID:19444617 |
|
NCBI chr17:10,545,488...10,550,029
|
|
G |
Drd2 |
dopamine receptor D2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18363855 PMID:18555060 PMID:19940168 |
|
NCBI chr 8:58,605,403...58,669,339
|
|
G |
Drd3 |
dopamine receptor D3 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19940168 |
|
NCBI chr11:70,385,586...70,437,793
|
|
G |
Drd4 |
dopamine receptor D4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15274053 |
|
NCBI chr 1:205,825,937...205,829,124
|
|
G |
Ephx1 |
epoxide hydrolase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19598248 |
|
NCBI chr13:95,246,079...95,275,852
|
|
G |
Fhit |
fragile histidine triad diadenosine triphosphatase |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr15:16,365,401...17,872,901
|
|
G |
Fkbp15 |
FKBP prolyl isomerase family member 15 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr 5:75,750,786...75,815,038
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
|
ISO IEP |
CTD Direct Evidence: marker/mechanism protein:increased expression:nucleus accumbens,striatum mRNA:increased expression:nucleus accumbens |
CTD RGD |
PMID:19689456 PMID:18834549 PMID:24183790 |
RGD:405255667, RGD:405100720 |
NCBI chr 6:110,852,188...110,855,054
|
|
G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
|
ISO IEP |
protein:increased expression:ventral tegmental area, nucleus accumbens (mouse) associated with stress related disorder;protein:increased expression:brain (rat) |
RGD |
PMID:28782589 PMID:27672362 PMID:31373119 |
RGD:401900303, RGD:401901183, RGD:401900735 |
NCBI chr 1:88,082,324...88,089,506
|
|
G |
Gabbr1 |
gamma-aminobutyric acid type B receptor subunit 1 |
susceptibility |
ISO |
DNA:SNPs, halotypes:intron (rs2076483,rs29221,rs715044) (human) |
RGD |
PMID:30143926 |
RGD:401940101 |
NCBI chr20:1,469,779...1,499,352
|
|
G |
Gabrg2 |
gamma-aminobutyric acid type A receptor subunit gamma 2 |
sexual_dimorphism |
ISO |
CTD Direct Evidence: marker/mechanism DNA:missense mutation:exon 8:p.K289M (rs4480617) (human) |
CTD RGD |
PMID:15772696 PMID:14569258 |
RGD:402528887 |
NCBI chr10:26,876,926...26,965,523
|
|
G |
Gad1 |
glutamate decarboxylase 1 |
susceptibility |
ISO |
DNA:haplotype: :rs769404���rs701492(human) |
RGD |
PMID:27967329 |
RGD:401900122 |
NCBI chr 3:75,777,260...75,818,099
|
|
G |
Gad2 |
glutamate decarboxylase 2 |
susceptibility |
ISO |
DNA:SNP: :rs2236418(human) |
RGD |
PMID:27967329 |
RGD:401900122 |
NCBI chr17:89,671,718...89,734,246
|
|
G |
Gdnf |
glial cell derived neurotrophic factor |
treatment |
ISO IEP |
CTD Direct Evidence: marker/mechanism protein:increased expression:nucleus accumbens, ventral tegmental area |
CTD RGD |
PMID:17356005 PMID:37904065 PMID:23432945 |
RGD:596938173, RGD:405850210 |
NCBI chr 2:58,621,327...58,647,242
|
|
G |
Gria1 |
glutamate ionotropic receptor AMPA type subunit 1 |
|
IEP |
methamphetamine abuse;protein:increased expression:hippocampal formation, striatum, prefrontal cortex (rat) |
RGD |
PMID:37778205 |
RGD:405100237 |
NCBI chr10:41,710,540...42,030,105
|
|
G |
Gria2 |
glutamate ionotropic receptor AMPA type subunit 2 |
|
IMP |
|
RGD |
PMID:16311338 |
RGD:596933067 |
NCBI chr 2:168,247,490...168,367,616
|
|
G |
Grm2 |
glutamate metabotropic receptor 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20211215 |
|
NCBI chr 8:116,158,810...116,171,857
|
|
G |
Gstm1 |
glutathione S-transferase mu 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19254865 |
|
NCBI chr 2:198,338,005...198,346,007
|
|
G |
Gstp1 |
glutathione S-transferase pi 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15729709 |
|
NCBI chr 1:210,767,237...210,770,242
|
|
G |
Gstt1 |
glutathione S-transferase theta 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18186040 PMID:19254865 |
|
NCBI chr20:12,856,068...12,873,020
|
|
G |
Hdac8 |
histone deacetylase 8 |
|
IEP |
mRNA:decreased expression:striatum (rat) |
RGD |
PMID:25452209 |
RGD:9681719 |
NCBI chr X:67,385,288...67,593,014
|
|
G |
Hs3st4 |
heparan sulfate-glucosamine 3-sulfotransferase 4 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr 1:178,539,078...178,944,850
|
|
G |
Htr1b |
5-hydroxytryptamine receptor 1B |
|
ISO |
CTD Direct Evidence: therapeutic |
CTD |
PMID:10780831 |
|
NCBI chr 8:91,395,405...91,414,815
|
|
G |
Htr3a |
5-hydroxytryptamine receptor 3A |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19689456 |
|
NCBI chr 8:58,138,514...58,150,960
|
|
G |
Htr6 |
5-hydroxytryptamine receptor 6 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20705401 |
|
NCBI chr 5:156,579,901...156,595,147
|
|
G |
Large1 |
LARGE xylosyl- and glucuronyltransferase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr19:11,603,129...12,048,930
|
|
G |
Lingo2 |
leucine rich repeat and Ig domain containing 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr 5:50,370,744...51,687,252
|
|
G |
Map2k5 |
mitogen activated protein kinase kinase 5 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr 8:72,520,616...72,748,395
|
|
G |
Mb |
myoglobin |
|
ISO |
|
RGD |
PMID:12935649 |
RGD:458925289 |
NCBI chr 7:110,640,511...110,647,742
|
|
G |
Mtarc1 |
mitochondrial amidoxime reducing component 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr13:96,324,377...96,362,677
|
|
G |
Mtarc2 |
mitochondrial amidoxime reducing component 2 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr13:96,362,810...96,397,284
|
|
G |
Myo5b |
myosin Vb |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr18:70,313,717...70,613,918
|
|
G |
Nos1 |
nitric oxide synthase 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15542708 |
|
NCBI chr12:44,276,011...44,456,371
|
|
G |
Npy1r |
neuropeptide Y receptor Y1 |
|
ISO |
CTD Direct Evidence: marker/mechanism DNA:SNP:intron: (rs7687423) (human) |
CTD RGD |
PMID:19566775 PMID:19566775 |
RGD:402463941 |
NCBI chr16:27,804,416...27,814,070
|
|
G |
Nrg1 |
neuregulin 1 |
|
ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
|
NCBI chr16:65,954,084...67,007,484
|
|
G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
|
IEP ISO |
mRNA:increased expression:nucleus accumbens protein:increased expression:frontal cortex, striatum protein:altered expression:nucleus accumbens, ventral tegmental area |
RGD |
PMID:33961872 PMID:31693929 PMID:37904065 PMID:34273388 |
RGD:596936246, RGD:597015747, RGD:596938173, RGD:596938171 |
NCBI chr17:5,560,558...5,875,899
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G |
Oprm1 |
opioid receptor, mu 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:16402083 |
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NCBI chr 1:45,565,371...45,818,722
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G |
PCOLCE2 |
procollagen C-endopeptidase enhancer 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 8:96,193,461...96,251,116
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G |
Pde4b |
phosphodiesterase 4B |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 5:122,028,956...122,598,267
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G |
Pde4d |
phosphodiesterase 4D |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 2:41,748,337...43,262,567
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G |
Pde6c |
phosphodiesterase 6C |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 1:235,909,583...235,965,435
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G |
Pdyn |
prodynorphin |
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ISO IEP |
CTD Direct Evidence: marker/mechanism mRNA:increased expression:nucleus acccumbens mRNA:increased expression:nucleus accumbens mRNA:increased expression:central amygdaloid nucleus mRNA:altered expression:brain DNA:repeat:promoter:rs35286251 (human) |
CTD RGD |
PMID:16529859 PMID:27989838 PMID:22390687 PMID:12523490 PMID:16289352 PMID:16529859 More...
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RGD:401851910, RGD:401851043, RGD:401850585, RGD:401850564, RGD:401850552 |
NCBI chr 3:137,354,161...137,366,503
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G |
Pick1 |
protein interacting with PRKCA 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17606663 |
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NCBI chr 7:112,676,890...112,697,275
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G |
Plat |
plasminogen activator, tissue type |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:15659235 |
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NCBI chr16:75,943,061...76,022,037
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G |
Pou5f1 |
POU class 5 homeobox 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr20:3,227,836...3,232,598
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G |
Prdm2 |
PR/SET domain 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 5:155,421,066...155,531,884
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G |
Prkaca |
protein kinase cAMP-activated catalytic subunit alpha |
treatment |
IEP |
protein:increased expression, increased phosphorylation:nucleus accumbens, ventral tegmental area |
RGD |
PMID:31900897 |
RGD:401938636 |
NCBI chr19:41,059,843...41,083,189
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G |
Prkg1 |
protein kinase cGMP-dependent 1 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 1:237,818,950...239,052,184
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G |
Prokr2 |
prokineticin receptor 2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:20576534 |
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NCBI chr 3:119,624,738...119,639,442
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G |
Psd3 |
pleckstrin and Sec7 domain containing 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr16:26,238,595...26,802,535
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G |
Raly |
RALY heterogeneous nuclear ribonucleoprotein |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 3:143,306,039...143,370,542
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G |
Rapgef5 |
Rap guanine nucleotide exchange factor 5 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 6:138,445,184...138,679,943
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19689456 |
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NCBI chr 1:212,354,336...212,364,815
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G |
Rgs17 |
regulator of G-protein signaling 17 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 1:44,627,583...44,729,957
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G |
Serpina5 |
serpin family A member 5 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 6:123,009,224...123,028,412
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G |
Sgcz |
sarcoglycan zeta |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr16:53,660,283...54,740,811
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G |
Sh3rf3 |
SH3 domain containing ring finger 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr20:26,765,278...27,099,261
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G |
Slc6a3 |
solute carrier family 6 member 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:12931138 |
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NCBI chr 1:31,537,990...31,578,962
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G |
Slc6a4 |
solute carrier family 6 member 4 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:19689456 |
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NCBI chr10:62,322,688...62,357,060
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G |
Slc6a9 |
solute carrier family 6 member 9 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:17582620 |
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NCBI chr 5:136,660,022...136,694,173
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G |
Smyd3 |
SET and MYND domain containing 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr13:90,709,263...91,266,209
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G |
Snca |
synuclein alpha |
treatment |
IMP ISO |
CTD Direct Evidence: marker/mechanism |
CTD RGD |
PMID:15542733 PMID:32278788 PMID:20551914 |
RGD:13506280 |
NCBI chr 4:91,026,474...91,127,444
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G |
Trpm3 |
transient receptor potential cation channel, subfamily M, member 3 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 1:219,673,200...220,557,610
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G |
Usp48 |
ubiquitin specific peptidase 48 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr 5:149,800,189...149,867,838
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G |
Zfp385d |
zinc finger protein 385D |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr15:5,040,182...5,849,975
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G |
Zfp423 |
zinc finger protein 423 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:18316681 |
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NCBI chr19:35,282,149...35,580,775
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
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ISO |
mRNA:increased expression:hippocampal formation (mouse) |
RGD |
PMID:15994025 |
RGD:405866348 |
NCBI chr 1:176,766,222...176,864,741
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G |
Clock |
clock circadian regulator |
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ISO |
mRNA:increased expression:hippocampal formation (mouse) |
RGD |
PMID:15994025 |
RGD:405866348 |
NCBI chr14:32,262,747...32,346,872
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G |
Cry1 |
cryptochrome circadian regulator 1 |
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ISO |
mRNA:increased expression:hippocampal formation (mouse) |
RGD |
PMID:15994025 |
RGD:405866347 |
NCBI chr 7:18,529,823...18,594,092
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G |
Per1 |
period circadian regulator 1 |
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ISO |
mRNA:decreased expression: hippocampal formation, caudate-putamen (mouse) |
RGD |
PMID:15994025 |
RGD:405866348 |
NCBI chr10:54,299,002...54,313,804
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G |
Per2 |
period circadian regulator 2 |
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ISO |
mRNA:increased expression, decreased expression:hippocampal formation, caudate-putamen (mouse) |
RGD |
PMID:15994025 |
RGD:405866348 |
NCBI chr 9:99,454,828...99,497,069
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G |
Ache |
acetylcholinesterase |
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IEP |
mRNA:decreased expression:basal forebrain cholinergic neurons |
RGD |
PMID:37402853 |
RGD:597538603 |
NCBI chr12:25,042,882...25,050,608
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G |
Adh1c |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
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IEP |
mRNA:altered exxpression:liver (rat) |
RGD |
PMID:23413777 |
RGD:405100715 |
NCBI chr 2:226,797,303...226,808,892
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G |
Adh4 |
alcohol dehydrogenase 4 (class II), pi polypeptide |
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IEP |
mRNA:altered exxpression:liver (rat) |
RGD |
PMID:23413777 |
RGD:405100715 |
NCBI chr 2:226,948,717...226,966,747
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G |
Bdnf |
brain-derived neurotrophic factor |
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IEP |
protein:altered expression:amygdala, pyriform cortex, bed nucleus of stria terminalis |
RGD |
PMID:23588198 |
RGD:405849391 |
NCBI chr 3:116,619,633...116,670,212
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G |
Car3 |
carbonic anhydrase 3 |
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IEP |
associated with Alcoholic Liver Diseases;protein:decreased expression:liver |
RGD |
PMID:22545783 |
RGD:7495839 |
NCBI chr 2:88,491,666...88,501,299
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
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IEP |
mRNA:increased expression:frontal cortex mRNA:increased expression:basal forebrain cholinergic neurons |
RGD |
PMID:23867237 PMID:37402853 |
RGD:597538460, RGD:597538603 |
NCBI chr10:67,503,077...67,504,875
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G |
Chat |
choline O-acetyltransferase |
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IEP |
mRNA:decreased expression:basal forebrain cholinergic neurons |
RGD |
PMID:37402853 |
RGD:597538603 |
NCBI chr16:7,657,362...7,717,093
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G |
Chrna7 |
cholinergic receptor nicotinic alpha 7 subunit |
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IEP |
mRNA:decreased expression:basal forebrain cholinergic neurons |
RGD |
PMID:37402853 |
RGD:597538603 |
NCBI chr 1:126,123,425...126,249,181
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G |
Crhr1 |
corticotropin releasing hormone receptor 1 |
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IEP |
mRNA:decreased expression:adenohypophysis |
RGD |
PMID:11045867 |
RGD:407431640 |
NCBI chr10:89,540,192...89,583,466
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G |
Cybb |
cytochrome b-245 beta chain |
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IEP |
mRNA:increased expression:frontal cortex |
RGD |
PMID:23867237 |
RGD:597538460 |
NCBI chr X:16,030,596...16,065,065
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
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ISO IEP |
associated with Alcoholic Liver Diseases;protein:increased expression:liver mRNA:altered exxpression:liver (rat) protein:increased expression, increased nitration |
RGD |
PMID:25236742 PMID:22545783 PMID:23413777 PMID:29404485 PMID:25236742 |
RGD:14700891, RGD:7495839, RGD:405100715, RGD:14700911, RGD:14700891 |
NCBI chr 1:205,269,967...205,280,365
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G |
Dnmt1 |
DNA methyltransferase 1 |
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ISO |
protein:increased expression:nucleus accumbens: |
RGD |
PMID:23423140 |
RGD:9588287 |
NCBI chr 8:19,440,611...19,486,659
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G |
Drd1 |
dopamine receptor D1 |
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IEP |
associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) |
RGD |
PMID:23413777 |
RGD:405100715 |
NCBI chr17:10,545,488...10,550,029
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G |
Drd2 |
dopamine receptor D2 |
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IEP |
mRNA:altered exxpression:spleen (rat) |
RGD |
PMID:23413777 |
RGD:405100715 |
NCBI chr 8:58,605,403...58,669,339
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G |
Drd3 |
dopamine receptor D3 |
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IEP |
associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) |
RGD |
PMID:23413777 |
RGD:405100715 |
NCBI chr11:70,385,586...70,437,793
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G |
Drd4 |
dopamine receptor D4 |
susceptibility |
ISO IEP |
DNA:repeats:exon: mRNA:altered exxpression:spleen (rat) |
RGD |
PMID:19393859 PMID:23413777 |
RGD:401960068, RGD:405100715 |
NCBI chr 1:205,825,937...205,829,124
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G |
Efhd2 |
EF-hand domain family, member D2 |
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ISO |
CTD Direct Evidence: marker/mechanism |
CTD |
PMID:28397836 |
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NCBI chr 5:159,443,959...159,459,993
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G |
Ehmt2 |
euchromatic histone lysine methyltransferase 2 |
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IEP |
mRNA:increased expression:basal forebrain cholinergic neurons |
RGD |
PMID:37402853 |
RGD:597538603 |
NCBI chr20:3,924,263...3,941,238
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G |
Fn1 |
fibronectin 1 |
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IEP |
mRNA:increased expression:frontal cortex |
RGD |
PMID:23867237 |
RGD:597538460 |
NCBI chr 9:80,645,507...80,714,200
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
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IEP |
protein:increased expression:prefrontal cortex |
RGD |
PMID:29407478 |
RGD:405295494 |
NCBI chr 6:110,852,188...110,855,054
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G |
Gabra1 |
gamma-aminobutyric acid type A receptor subunit alpha 1 |
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IEP |
associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) |
RGD |
PMID:23413777 |
RGD:405100715 |
NCBI chr10:27,096,731...27,152,563
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G |
Gabra2 |
gamma-aminobutyric acid type A receptor subunit alpha 2 |
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IEP |
associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) |
RGD |
PMID:23413777 |
RGD:405100715 |
NCBI chr14:37,451,218...37,587,458
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G |
Gabra3 |
gamma-aminobutyric acid type A receptor subunit alpha 3 |
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IEP |
associated with human immunodeficiency virus infectious disease;mRNA:altered expression:liver,spleen (rat) |
RGD |
PMID:23413777 |
RGD:405100715 |
NCBI chr X:150,244,745...150,501,566
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G |
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