HSD11B2 (hydroxysteroid 11-beta dehydrogenase 2) - Rat Genome Database

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Gene: HSD11B2 (hydroxysteroid 11-beta dehydrogenase 2) Pan paniscus
Analyze
Symbol: HSD11B2
Name: hydroxysteroid 11-beta dehydrogenase 2
RGD ID: 11930509
Description: ENCODES a protein that exhibits 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity (ortholog); NAD binding (ortholog); steroid binding (ortholog); INVOLVED IN female pregnancy (ortholog); glucocorticoid metabolic process (ortholog); regulation of blood volume by renal aldosterone (ortholog); PARTICIPATES IN 11-beta-hydroxylase deficiency pathway; 17-alpha-hydroxylase deficiency pathway; 21-alpha-hydroxylase deficiency pathway; ASSOCIATED WITH apparent mineralocorticoid excess syndrome (ortholog); asthma (ortholog); Fetal Growth Retardation (ortholog); FOUND IN cytoplasm (ortholog); intracellular membrane-bounded organelle (ortholog); lipid droplet (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: corticosteroid 11-beta-dehydrogenase isozyme 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11667,150,354 - 67,171,417 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1667,165,215 - 67,171,417 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01647,776,118 - 47,782,861 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
HSD11B2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11667,150,354 - 67,171,417 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1667,165,215 - 67,171,417 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01647,776,118 - 47,782,861 (+)NCBIMhudiblu_PPA_v0panPan3
HSD11B2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1667,430,652 - 67,437,553 (+)EnsemblGRCh38hg38GRCh38
GRCh381667,431,121 - 67,437,553 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371667,465,024 - 67,471,456 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361666,022,537 - 66,028,957 (+)NCBINCBI36hg18NCBI36
Build 341666,022,536 - 66,028,953NCBI
Celera1651,973,237 - 51,979,660 (+)NCBI
Cytogenetic Map16q22.1NCBI
HuRef1653,338,306 - 53,344,605 (+)NCBIHuRef
CHM1_11668,872,417 - 68,878,837 (+)NCBICHM1_1
Hsd11b2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398106,245,378 - 106,250,620 (+)NCBIGRCm39mm39
GRCm39 Ensembl8106,245,387 - 106,250,620 (+)Ensembl
GRCm388105,518,746 - 105,523,988 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,518,755 - 105,523,988 (+)EnsemblGRCm38mm10GRCm38
MGSCv378108,042,646 - 108,047,888 (+)NCBIGRCm37mm9NCBIm37
MGSCv368108,407,983 - 108,412,647 (+)NCBImm8
Celera8109,741,823 - 109,747,238 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Hsd11b2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21933,397,656 - 33,402,899 (+)NCBI
Rnor_6.0 Ensembl1937,476,095 - 37,481,307 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01937,476,083 - 37,481,326 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01948,341,841 - 48,347,084 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41935,336,342 - 35,341,585 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11935,341,222 - 35,346,466 (+)NCBI
Celera1932,826,007 - 32,831,250 (+)NCBICelera
Cytogenetic Map19q12NCBI
Hsd11b2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554849,206,681 - 9,212,356 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554849,206,681 - 9,212,356 (-)NCBIChiLan1.0ChiLan1.0
HSD11B2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1581,966,397 - 81,970,301 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl581,966,937 - 81,968,991 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha581,956,062 - 81,961,586 (-)NCBI
ROS_Cfam_1.0582,401,695 - 82,407,218 (-)NCBI
UMICH_Zoey_3.1582,227,839 - 82,233,361 (-)NCBI
UNSW_CanFamBas_1.0581,908,941 - 81,914,465 (-)NCBI
UU_Cfam_GSD_1.0582,552,387 - 82,557,914 (-)NCBI
Hsd11b2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,700,829 - 41,706,486 (-)NCBI
SpeTri2.0NW_00493647517,882,663 - 17,888,708 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSD11B2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl628,083,955 - 28,089,672 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1628,084,087 - 28,089,256 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2625,351,178 - 25,356,346 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSD11B2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1560,017,967 - 60,040,959 (-)NCBI
ChlSab1.1 Ensembl560,019,434 - 60,025,353 (-)Ensembl
Hsd11b2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474618,883,587 - 18,889,205 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034940444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide SSBP01000338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000047040   ⟹   ENSPPAP00000024215
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1667,165,215 - 67,171,417 (+)Ensembl
RefSeq Acc Id: XM_034940444   ⟹   XP_034796335
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v01647,776,118 - 47,782,861 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034796335 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_034796335   ⟸   XM_034940444
RefSeq Acc Id: ENSPPAP00000024215   ⟸   ENSPPAT00000047040


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035249 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000024215 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047040 UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene HSD11B2 ENTREZGENE
Pfam adh_short UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A2R9B7K4_PANPA UniProtKB/TrEMBL