ACHE (acetylcholinesterase (Yt blood group)) - Rat Genome Database

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Gene: ACHE (acetylcholinesterase (Yt blood group)) Pan paniscus
Analyze
Symbol: ACHE
Name: acetylcholinesterase (Yt blood group) (Ensembl:acetylcholinesterase (Cartwright blood group))
RGD ID: 11910443
Description: ENCODES a protein that exhibits acetylcholine binding (ortholog); acetylcholinesterase activity (ortholog); choline binding (ortholog); INVOLVED IN acetylcholine catabolic process (ortholog); acetylcholine metabolic process (ortholog); acetylcholine receptor signaling pathway (ortholog); PARTICIPATES IN acetylcholine metabolic pathway; acetylcholine signaling pathway via muscarinic acetylcholine receptor; acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH acute stress disorder (ortholog); Alzheimer's disease (ortholog); amphetamine abuse (ortholog); FOUND IN axolemma (ortholog); axon (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acetylcholinesterase; acetylcholinesterase (Cartwright blood group)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,793,619 - 118,800,634 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17167,058,249 - 167,065,263 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,915,065 - 92,922,079 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17106,311,944 - 106,318,190 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,311,944 - 106,318,184 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ACHE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,793,619 - 118,800,634 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17167,058,249 - 167,065,263 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,915,065 - 92,922,079 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17106,311,944 - 106,318,190 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,311,944 - 106,318,184 (-)Ensemblpanpan1.1panPan2
ACHE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,889,994 - 100,896,994 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,889,994 - 100,896,974 (-)EnsemblGRCh38hg38GRCh38
GRCh377100,487,615 - 100,494,614 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,325,551 - 100,331,477 (-)NCBINCBI36Build 36hg18NCBI36
Build 347100,132,268 - 100,138,147NCBI
Celera795,218,191 - 95,224,120 (-)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef795,117,968 - 95,123,900 (-)NCBIHuRef
CHM1_17100,418,205 - 100,424,133 (-)NCBICHM1_1
T2T-CHM13v2.07102,130,076 - 102,137,081 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,847,220 - 99,853,146 (-)NCBI
Ache
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,286,516 - 137,292,728 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,285,781 - 137,292,728 (+)EnsemblGRCm39 Ensembl
GRCm385137,288,247 - 137,294,466 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,287,519 - 137,294,466 (+)EnsemblGRCm38mm10GRCm38
MGSCv375137,729,505 - 137,735,691 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365137,518,065 - 137,524,251 (+)NCBIMGSCv36mm8
Celera5134,271,243 - 134,277,456 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.32NCBI
Ache
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81225,042,882 - 25,050,608 (-)NCBIGRCr8
mRatBN7.21219,406,133 - 19,413,713 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1219,407,360 - 19,413,651 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1220,562,456 - 20,567,072 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,175,159 - 21,179,775 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01220,239,717 - 20,244,333 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,472,358 - 22,477,052 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,472,358 - 22,478,753 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,487,632 - 24,491,360 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1221,207,976 - 21,212,604 (-)NCBICelera
Cytogenetic Map12q12NCBI
Ache
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495557380,298 - 85,799 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495557379,606 - 85,799 (+)NCBIChiLan1.0ChiLan1.0
ACHE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.168,874,747 - 8,879,926 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl68,873,584 - 8,879,702 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,580,127 - 10,585,994 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.068,809,869 - 8,815,742 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl68,809,457 - 8,816,935 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.168,661,436 - 8,668,230 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.068,640,504 - 8,646,368 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.068,822,240 - 8,828,117 (+)NCBIUU_Cfam_GSD_1.0
Ache
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,174,520 - 133,179,854 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543856,676 - 862,109 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543856,678 - 862,080 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACHE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,732,441 - 8,738,605 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,732,451 - 8,738,274 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.238,159,377 - 8,165,197 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ACHE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,328,304 - 12,335,302 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,331,039 - 12,335,076 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,993,802 - 4,000,839 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ache
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,275,117 - 16,281,793 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,275,108 - 16,280,639 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000046269   ⟹   ENSPPAP00000023445
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7106,311,944 - 106,318,184 (-)Ensembl
RefSeq Acc Id: XM_034964625   ⟹   XP_034820516
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26118,793,619 - 118,800,623 (-)NCBI
NHGRI_mPanPan17167,058,249 - 167,065,250 (-)NCBI
Mhudiblu_PPA_v0792,915,065 - 92,922,064 (-)NCBI
RefSeq Acc Id: XM_034964626   ⟹   XP_034820517
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26118,793,619 - 118,800,634 (-)NCBI
NHGRI_mPanPan17167,058,249 - 167,065,263 (-)NCBI
Mhudiblu_PPA_v0792,915,065 - 92,922,079 (-)NCBI
RefSeq Acc Id: XM_034964627   ⟹   XP_034820518
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26118,793,619 - 118,800,634 (-)NCBI
NHGRI_mPanPan17167,058,249 - 167,065,263 (-)NCBI
Mhudiblu_PPA_v0792,915,065 - 92,922,079 (-)NCBI
RefSeq Acc Id: XM_034964628   ⟹   XP_034820519
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26118,793,619 - 118,799,583 (-)NCBI
NHGRI_mPanPan17167,058,249 - 167,064,205 (-)NCBI
Mhudiblu_PPA_v0792,915,065 - 92,921,027 (-)NCBI
RefSeq Acc Id: XM_034964629   ⟹   XP_034820520
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26118,793,619 - 118,799,583 (-)NCBI
NHGRI_mPanPan17167,058,249 - 167,064,209 (-)NCBI
Mhudiblu_PPA_v0792,915,065 - 92,921,027 (-)NCBI
RefSeq Acc Id: XM_057302914   ⟹   XP_057158897
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26118,793,619 - 118,798,299 (-)NCBI
NHGRI_mPanPan17167,058,249 - 167,062,929 (-)NCBI
RefSeq Acc Id: XP_034820518   ⟸   XM_034964627
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034820517   ⟸   XM_034964626
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034820516   ⟸   XM_034964625
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034820519   ⟸   XM_034964628
- Peptide Label: isoform X4
RefSeq Acc Id: XP_034820520   ⟸   XM_034964629
- Peptide Label: isoform X4
Ensembl Acc Id: ENSPPAP00000023445   ⟸   ENSPPAT00000046269
RefSeq Acc Id: XP_057158897   ⟸   XM_057302914
- Peptide Label: isoform X4
Protein Domains
Carboxylesterase type B


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034898 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046269.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AChE-related_enzymes UniProtKB/TrEMBL
  CarbesteraseB UniProtKB/TrEMBL
  Carboxylesterase_B_AS UniProtKB/TrEMBL
  Carboxylesterase_B_CS UniProtKB/TrEMBL
  Cholinesterase UniProtKB/TrEMBL
NCBI Gene ACHE ENTREZGENE
PANTHER ACETYLCHOLINESTERASE UniProtKB/TrEMBL
  ACETYLCHOLINESTERASE UniProtKB/TrEMBL
Pfam COesterase UniProtKB/TrEMBL
PRINTS CHOLNESTRASE UniProtKB/TrEMBL
PROSITE CARBOXYLESTERASE_B_1 UniProtKB/TrEMBL
  CARBOXYLESTERASE_B_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A2R9B1H5_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-03-13 ACHE  acetylcholinesterase (Yt blood group)  ACHE  acetylcholinesterase (Cartwright blood group)  Symbol and/or name change 5135510 APPROVED