RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: plague
Accession: DOID:3482
browse the term
Definition: A primary bacterial infectious disease that results_in infection, located_in lymph node, located_in vasculature or located_in lungs, has_material_basis_in Yersinia pestis, which is transmitted_by oriental rat flea (Xenopsylla cheopis) infected by feeding on rodents and other mammals, transmitted_by air, transmitted_by direct contact or transmitted_by ingestion of contaminated undercooked food. (DO)
Synonyms: exact_synonym: Black Plague; Meningeal Plague; Meningeal Plagues; Pulmonic Plague; Yersinia pestis infections; Yersinia pestis infectious disease; black plagues; pulmonic plagues
related_synonym: N-FORMYLPEPTIDE RECEPTOR POLYMORPHISM
primary_id: MESH:D010930
xref: EFO:0009425 ; ICD10CM:A20 ; ICD9CM:020 ; NCI:C85015
For additional species annotation, visit the
Alliance of Genome Resources .
Please select species to view GViewer data.
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
G
CCR5
C-C motif chemokine receptor 5
resistance
ISO
DNA:polymorphism:cds:p.H184R (rat)
RGD
PMID:18703167
RGD:4890425
NCBI chr22:7,803,794...7,818,112
G
P
CCR5
C-C motif chemokine receptor 5
resistance
ISO
DNA:polymorphism:cds:p.H184R (rat)
RGD
PMID:18703167
RGD:4890425
NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895
G
D
CCR5
C-C motif chemokine receptor 5
resistance
ISO
DNA:polymorphism:cds:p.H184R (rat)
RGD
PMID:18703167
RGD:4890425
NCBI chr20:42,293,288...42,297,952
Ensembl chr20:42,294,996...42,297,952
G
B
CCR5
C-C motif chemokine receptor 5
resistance
ISO
DNA:polymorphism:cds:p.H184R (rat)
RGD
PMID:18703167
RGD:4890425
NCBI chr 3:46,273,096...46,278,471
Ensembl chr 3:47,380,321...47,381,379
G
R
Ccr5
C-C motif chemokine receptor 5
resistance
IAGP
DNA:polymorphism:cds:p.H184R (rat)
RGD
PMID:18703167
RGD:4890425
NCBI chr 8:132,629,097...132,660,980
Ensembl chr 8:123,752,325...123,759,260
G
M
Ccr5
C-C motif chemokine receptor 5
resistance
ISO
DNA:polymorphism:cds:p.H184R (rat)
RGD
PMID:18703167
RGD:4890425
NCBI chr 9:123,921,557...123,934,153
Ensembl chr 9:123,921,580...123,947,736
G
H
CCR5
C-C motif chemokine receptor 5
resistance
ISO
DNA:polymorphism:cds:p.H184R (rat)
RGD
PMID:18703167
RGD:4890425
NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206
G
G
CXCL1
C-X-C motif chemokine ligand 1
ISO
RGD
PMID:21356370
RGD:5134954
NCBI chr 7:22,327,041...22,329,405
Ensembl chr 7:22,569,355...22,569,900 Ensembl chr 7:22,569,355...22,569,900
G
R
Cxcl1
C-X-C motif chemokine ligand 1
ISO
RGD
PMID:21356370
RGD:5134954
NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,193,365...17,195,215
G
M
Cxcl1
C-X-C motif chemokine ligand 1
IMP
RGD
PMID:21356370
RGD:5134954
NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
G
H
CXCL1
C-X-C motif chemokine ligand 1
ISO
RGD
PMID:21356370
RGD:5134954
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
G
G
ERAP2
endoplasmic reticulum aminopeptidase 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:36261521
NCBI chr 4:90,707,064...90,754,413
Ensembl chr 4:90,707,181...90,752,325
G
P
ERAP2
endoplasmic reticulum aminopeptidase 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:36261521
NCBI chr 2:103,510,425...103,563,482
Ensembl chr 2:103,510,441...103,564,437
G
S
Erap2
endoplasmic reticulum aminopeptidase 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:36261521
NCBI chrNW_004936523:6,545,281...6,584,403
Ensembl chrNW_004936523:6,544,207...6,584,452
G
D
ERAP2
endoplasmic reticulum aminopeptidase 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:36261521
NCBI chr 3:12,780,084...12,819,795
Ensembl chr 3:12,781,849...12,817,025
G
B
ERAP2
endoplasmic reticulum aminopeptidase 2
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:36261521
NCBI chr 5:92,186,786...92,231,020
Ensembl chr 5:97,741,678...97,785,071
G
H
ERAP2
endoplasmic reticulum aminopeptidase 2
EXP
CTD Direct Evidence: therapeutic
CTD
PMID:36261521
NCBI chr 5:96,875,939...96,919,716
Ensembl chr 5:96,875,986...96,919,703
G
N
Il17a
interleukin 17A
ISO
mRNA,protein:increased expression:lymph node
RGD
PMID:20876291
RGD:4781452
NCBI chrNW_004624855:3,911,349...3,914,214
Ensembl chrNW_004624855:3,911,349...3,913,136
G
G
IL17A
interleukin 17A
ISO
mRNA,protein:increased expression:lymph node
RGD
PMID:20876291
RGD:4781452
NCBI chr17:20,314,082...20,319,917
Ensembl chr17:20,315,773...20,318,785
G
P
IL17A
interleukin 17A
ISO
mRNA,protein:increased expression:lymph node
RGD
PMID:20876291
RGD:4781452
NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153
G
S
Il17a
interleukin 17A
ISO
mRNA,protein:increased expression:lymph node
RGD
PMID:20876291
RGD:4781452
NCBI chrNW_004936476:8,621,860...8,625,008
Ensembl chrNW_004936476:8,621,860...8,625,008
G
D
IL17A
interleukin 17A
ISO
mRNA,protein:increased expression:lymph node
RGD
PMID:20876291
RGD:4781452
NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513
G
B
IL17A
interleukin 17A
ISO
mRNA,protein:increased expression:lymph node
RGD
PMID:20876291
RGD:4781452
NCBI chr 6:51,736,269...51,740,538
Ensembl chr 6:53,004,820...53,009,074
G
C
Il17a
interleukin 17A
ISO
mRNA,protein:increased expression:lymph node
RGD
PMID:20876291
RGD:4781452
NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962
G
R
Il17a
interleukin 17A
IEP
mRNA,protein:increased expression:lymph node
RGD
PMID:20876291
RGD:4781452
NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:23,144,402...23,147,889
G
M
Il17a
interleukin 17A
ISO
mRNA,protein:increased expression:lymph node
RGD
PMID:20876291
RGD:4781452
NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720
G
H
IL17A
interleukin 17A
ISO
mRNA,protein:increased expression:lymph node
RGD
PMID:20876291
RGD:4781452
NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638
G
N
Il1b
interleukin 1 beta
ISO
RGD
PMID:20565713
RGD:4142820
NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760
G
G
IL1B
interleukin 1 beta
ISO
RGD
PMID:20565713
RGD:4142820
NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729
G
S
Il1b
interleukin 1 beta
ISO
RGD
PMID:20565713
RGD:4142820
NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165
G
D
IL1B
interleukin 1 beta
ISO
RGD
PMID:20565713
RGD:4142820
NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458
G
B
IL1B
interleukin 1 beta
ISO
RGD
PMID:20565713
RGD:4142820
NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424
G
C
Il1b
interleukin 1 beta
ISO
RGD
PMID:20565713
RGD:4142820
NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947
G
R
Il1b
interleukin 1 beta
ISO
RGD
PMID:20565713
RGD:4142820
NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
G
M
Il1b
interleukin 1 beta
IMP
RGD
PMID:20565713
RGD:4142820
NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
G
H
IL1B
interleukin 1 beta
ISO
RGD
PMID:20565713
RGD:4142820
NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
G
B
LOC100976904
growth-regulated alpha protein
ISO
RGD
PMID:21356370
RGD:5134954
NCBI chr 4:50,325,248...50,327,165
Ensembl chr 4:56,153,899...56,159,474
G
P
LOC110258578
interleukin-1 beta-like
ISO
RGD
PMID:20565713
RGD:4142820
G
N
Mavs
mitochondrial antiviral signaling protein
susceptibility
ISO
RGD
PMID:25064677
RGD:40903046
NCBI chrNW_004624741:4,936,556...4,951,081
Ensembl chrNW_004624741:4,939,040...4,954,058
G
G
MAVS
mitochondrial antiviral signaling protein
susceptibility
ISO
RGD
PMID:25064677
RGD:40903046
NCBI chr 2:34,534,433...34,555,406
Ensembl chr 2:34,541,229...34,552,823
G
P
MAVS
mitochondrial antiviral signaling protein
susceptibility
ISO
RGD
PMID:25064677
RGD:40903046
NCBI chr17:31,850,646...31,869,273
Ensembl chr17:31,850,900...31,869,188
G
S
Mavs
mitochondrial antiviral signaling protein
susceptibility
ISO
RGD
PMID:25064677
RGD:40903046
NCBI chrNW_004936485:14,842,778...14,859,163
Ensembl chrNW_004936485:14,842,160...14,859,202
G
D
MAVS
mitochondrial antiviral signaling protein
susceptibility
ISO
RGD
PMID:25064677
RGD:40903046
NCBI chr24:17,510,209...17,529,286
Ensembl chr24:17,512,761...17,523,807
G
B
MAVS
mitochondrial antiviral signaling protein
susceptibility
ISO
RGD
PMID:25064677
RGD:40903046
NCBI chr20:3,885,044...3,903,554
Ensembl chr20:3,659,559...3,701,089
G
C
Mavs
mitochondrial antiviral signaling protein
susceptibility
ISO
RGD
PMID:25064677
RGD:40903046
NCBI chrNW_004955415:14,691,918...14,704,782
Ensembl chrNW_004955415:14,695,438...14,703,672
G
R
Mavs
mitochondrial antiviral signaling protein
susceptibility
ISO
RGD
PMID:25064677
RGD:40903046
NCBI chr 3:138,904,673...138,919,129
Ensembl chr 3:118,451,743...118,466,094
G
M
Mavs
mitochondrial antiviral signaling protein
susceptibility
IMP
RGD
PMID:25064677
RGD:40903046
NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945
G
H
MAVS
mitochondrial antiviral signaling protein
susceptibility
ISO
RGD
PMID:25064677
RGD:40903046
NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123
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