CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: monodansylcadaverine
Accession: CHEBI:52007
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Definition: A sulfonamide obtained by formal condensation of the sulfo group of 5-(dimethylamino)naphthalene-1-sulfonic acid with one of the amino groups of cadaverine.
Synonyms: exact_synonym: N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide
related_synonym: Formula=C17H25N3O2S; InChI=1S/C17H25N3O2S/c1-20(2)16-10-6-9-15-14(16)8-7-11-17(15)23(21,22)19-13-5-3-4-12-18/h6-11,19H,3-5,12-13,18H2,1-2H3; InChIKey=MLEBFEHOJICQQS-UHFFFAOYSA-N; N-monodansyl-1,5-diaminopentane; N-monodansylcadaverine; SMILES=C=12C=CC=C(C1C=CC=C2N(C)C)S(NCCCCCN)(=O)=O; dansylcadaverine
xref: CAS:10121-91-2
xref_mesh: MESH:C008542
xref: PMID:10187805; PMID:10611475; PMID:10639491; PMID:10678916; PMID:11267763; PMID:1370626; PMID:15032081; PMID:15860017; PMID:1671567; PMID:19200877; PMID:19614676; PMID:2283373; PMID:27731976; PMID:3241430; PMID:3455600; PMID:3501621; PMID:6126266; PMID:6318763; PMID:6506032; PMID:6733135; PMID:6840850; PMID:7571412; PMID:7750517; PMID:7927796; PMID:88908; PMID:8972719; PMID:9219731; Reaxys:2951070
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Akt1
AKT serine/threonine kinase 1
decreases phosphorylation
ISO
monodansylcadaverine results in decreased phosphorylation of AKT1 protein
CTD
PMID:16170020
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Bad
BCL2-associated agonist of cell death
decreases expression
ISO
monodansylcadaverine results in decreased expression of BAD protein
CTD
PMID:16170020
NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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Bcl2l11
Bcl2-like 11
increases expression
ISO
monodansylcadaverine results in increased expression of BCL2L11 protein
CTD
PMID:16170020
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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Birc5
baculoviral IAP repeat-containing 5
decreases expression
ISO
monodansylcadaverine results in decreased expression of BIRC5 protein
CTD
PMID:16170020
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Ccl25
C-C motif chemokine ligand 25
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL25 protein]
CTD
PMID:22341560
NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554
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Ccl5
C-C motif chemokine ligand 5
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CCL5 protein]
CTD
PMID:22341560
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Cxcl12
C-X-C motif chemokine ligand 12
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL12 protein]
CTD
PMID:22341560
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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Gsk3b
glycogen synthase kinase 3 beta
decreases expression
ISO
monodansylcadaverine results in decreased expression of GSK3B protein
CTD
PMID:16170020
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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Igf1
insulin-like growth factor 1
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [[IGF1 protein results in increased abundance of Reactive Oxygen Species] which results in increased expression of ZNF143 protein]; monodansylcadaverine inhibits the reaction [IGF1 protein results in increased abundance of Reactive Oxygen Species]
CTD
PMID:20733350
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Il12b
interleukin 12B
multiple interactions
ISO
monodansylcadaverine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL12B protein]
CTD
PMID:22341560
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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Il2
interleukin 2
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL2 protein]
CTD
PMID:22341560
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Il3
interleukin 3
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL3 protein]
CTD
PMID:22341560
NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
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Il4
interleukin 4
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL4 protein]
CTD
PMID:22341560
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il6
interleukin 6
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]
CTD
PMID:22341560
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Irf3
interferon regulatory factor 3
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased degradation of IRF3 protein]
CTD
PMID:22341560
NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
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Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein]
CTD
PMID:22341560
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein]
CTD
PMID:22341560
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]
CTD
PMID:22341560
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Nfkb1
nuclear factor kappa B subunit 1
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of NFKB1 protein]
CTD
PMID:22341560
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Tgm2
transglutaminase 2
decreases activity
ISO
monodansylcadaverine results in decreased activity of TGM2 protein
CTD
PMID:16382148
NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
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Ticam2
TIR domain containing adaptor molecule 2
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TICAM2 mRNA]
CTD
PMID:22341560
NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462
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Timp1
TIMP metallopeptidase inhibitor 1
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TIMP1 protein]
CTD
PMID:22341560
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Timp4
TIMP metallopeptidase inhibitor 4
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TIMP4 protein]
CTD
PMID:22341560
NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558
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Tlr4
toll-like receptor 4
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of TLR4 protein]
CTD
PMID:22341560
NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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Tnfrsf1a
TNF receptor superfamily member 1A
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNFRSF1A protein]
CTD
PMID:22341560
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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Zfp143
zinc finger protein 143
multiple interactions
ISO
monodansylcadaverine inhibits the reaction [[IGF1 protein results in increased abundance of Reactive Oxygen Species] which results in increased expression of ZNF143 protein]
CTD
PMID:20733350
NCBI chr 1:164,109,041...164,144,902
Ensembl chr 1:164,109,116...164,144,902
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