The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A tertiary amino compound that is 1,3,5-triazapenta-1,4-diene substituted by a methyl group at position 3 and 2,4-dimethylphenyl groups at positions 1 and 5.
[Idazoxan binds to and results in decreased activity of ADRA2A protein] which results in decreased susceptibility to amitraz; amitraz binds to and results in increased activity of ADRA2A protein amitraz results in decreased activity of ADRA2A protein
Tamoxifen inhibits the reaction [amitraz affects the expression of COMT mRNA]; Tamoxifen inhibits the reaction [amitraz affects the expression of COMT protein] amitraz affects the expression of COMT mRNA; amitraz affects the expression of COMT protein
Tamoxifen inhibits the reaction [amitraz results in increased expression of DBH mRNA]; Tamoxifen inhibits the reaction [amitraz results in increased expression of DBH protein] amitraz results in increased expression of DBH mRNA; amitraz results in increased expression of DBH protein
amitraz affects the expression of GAD2 mRNA [methylhistaprodifen co-treated with Idazoxan] inhibits the reaction [amitraz affects the expression of GAD2 mRNA]; Idazoxan inhibits the reaction [amitraz affects the expression of GAD2 mRNA]; methylhistaprodifen inhibits the reaction [amitraz affects the expression of GAD2 mRNA]
[methylhistaprodifen co-treated with Idazoxan] inhibits the reaction [amitraz results in increased expression of GLS mRNA]; methylhistaprodifen inhibits the reaction [amitraz results in increased expression of GLS mRNA]
amitraz results in increased expression of KEAP1 protein KEAP1 protein affects the reaction [amitraz results in decreased expression of CAT protein]; KEAP1 protein affects the reaction [amitraz results in decreased expression of NFE2L2 protein]; KEAP1 protein affects the reaction [amitraz results in decreased expression of NQO1 protein]; KEAP1 protein affects the reaction [amitraz results in decreased expression of SOD1 protein]
Tamoxifen inhibits the reaction [amitraz results in decreased expression of MAOA mRNA]; Tamoxifen inhibits the reaction [amitraz results in decreased expression of MAOA protein] amitraz results in decreased expression of MAOA mRNA; amitraz results in decreased expression of MAOA protein
amitraz results in decreased expression of MAOB mRNA; amitraz results in decreased expression of MAOB protein Tamoxifen inhibits the reaction [amitraz results in decreased expression of MAOB mRNA]; Tamoxifen inhibits the reaction [amitraz results in decreased expression of MAOB protein]
amitraz results in decreased expression of NFE2L2 protein KEAP1 protein affects the reaction [amitraz results in decreased expression of NFE2L2 protein]
Tamoxifen inhibits the reaction [amitraz results in increased expression of TH mRNA]; Tamoxifen inhibits the reaction [amitraz results in increased expression of TH protein] amitraz results in increased expression of TH mRNA; amitraz results in increased expression of TH protein