Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Myocardial Reperfusion Injury
go back to main search page
Accession:DOID:9007838 term browser browse the term
Definition:Damage to the MYOCARDIUM resulting from MYOCARDIAL REPERFUSION (restoration of blood flow to ischemic areas of the HEART.) Reperfusion takes place when there is spontaneous thrombolysis, THROMBOLYTIC THERAPY, collateral flow from other coronary vascular beds, or reversal of vasospasm.
Synonyms:exact_synonym: Myocardial Ischemic Reperfusion Injury;   Myocardial Reperfusion Injuries
 primary_id: MESH:D015428

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
Myocardial Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO RGD PMID:18316485 RGD:2301903 NCBI chrNW_004955414:32,216,243...32,289,028
Ensembl chrNW_004955414:32,216,196...32,289,053 		JBrowse link
G Acvr2b activin A receptor type 2B treatment ISO human construct in mouse model
mRNA, protein:decreased expression:heart (mouse)		 RGD PMID:30765322 RGD:329849112 NCBI chrNW_004955427:25,438,652...25,467,360
Ensembl chrNW_004955427:25,438,652...25,467,360 		JBrowse link
G Ada adenosine deaminase ISO protein:increased expression RGD PMID:16641873 RGD:1624305 NCBI chrNW_004955445:12,696,096...12,717,488
Ensembl chrNW_004955445:12,696,096...12,717,488 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:16155579 NCBI chrNW_004955420:20,911,181...20,922,992
Ensembl chrNW_004955420:20,912,348...20,914,402 		JBrowse link
G Adrb1 adrenoceptor beta 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10900253 PMID:17201736 RGD:5129149 NCBI chrNW_004955431:19,025,663...19,027,026 JBrowse link
G Adrb2 adrenoceptor beta 2 ISO RGD PMID:16269402 RGD:1598746 NCBI chrNW_004955415:5,515,157...5,517,198
Ensembl chrNW_004955415:5,515,697...5,516,980 		JBrowse link
G Ager advanced glycosylation end-product specific receptor ISO protein:increased expression:heart (rat) RGD PMID:16505177 RGD:1625342 NCBI chrNW_004955437:645,482...648,607
Ensembl chrNW_004955437:645,897...648,479 		JBrowse link
G Agl amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase ISO RGD PMID:9281456 RGD:1598779 NCBI chrNW_004955435:4,622,142...4,684,439
Ensembl chrNW_004955435:4,621,991...4,688,139 		JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2535056 PMID:19166939 NCBI chrNW_004955492:7,863,662...7,874,863
Ensembl chrNW_004955492:7,866,833...7,873,357 		JBrowse link
G Agtr1 angiotensin II receptor type 1 ISO protein:increased expression:myocardium RGD PMID:21078800 RGD:5129194 NCBI chrNW_004955474:8,733,942...8,781,305
Ensembl chrNW_004955474:8,733,942...8,781,255 		JBrowse link
G Ahr aryl hydrocarbon receptor treatment ISO RGD PMID:35788946 RGD:401793705 NCBI chrNW_004955410:20,428,531...20,459,482
Ensembl chrNW_004955410:20,428,546...20,456,836 		JBrowse link
G Aifm1 apoptosis inducing factor mitochondria associated 1 ISO protein:decreased expression:mitochondrion: RGD PMID:23685150 RGD:10053560 NCBI chrNW_004955473:4,891,955...4,925,705
Ensembl chrNW_004955473:4,891,955...4,926,428 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO protein:increased phosphorylation:heart left ventricle RGD PMID:20217242 RGD:5509104 NCBI chrNW_004955538:3,208,711...3,224,386
Ensembl chrNW_004955538:3,208,710...3,229,904 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO RGD PMID:16418318 RGD:2313347 NCBI chrNW_004955578:950,258...1,004,438
Ensembl chrNW_004955578:967,593...1,004,438 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9572063 NCBI chrNW_004955447:9,327...21,212 JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO RGD PMID:23468836 RGD:7241598 NCBI chrNW_004955482:8,352,569...8,383,097
Ensembl chrNW_004955482:8,352,569...8,384,899 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase ISO RGD PMID:20011686 RGD:2317527 NCBI chrNW_004955546:2,495,226...2,550,909
Ensembl chrNW_004955546:2,494,819...2,550,909 		JBrowse link
G Angpt2 angiopoietin 2 ISO mRNA, protein:increased expression:myocardium (rat) RGD PMID:12737621 RGD:1601505 NCBI chrNW_004955403:54,139,823...54,193,740
Ensembl chrNW_004955403:54,139,823...54,195,032 		JBrowse link
G Ank1 ankyrin 1 ISO RGD PMID:9378703 RGD:1599110 NCBI chrNW_004955536:1,049,325...1,237,943
Ensembl chrNW_004955536:1,049,407...1,237,943 		JBrowse link
G Ank2 ankyrin 2 ISO RGD PMID:9378703 RGD:1599110 NCBI chrNW_004955457:13,624,590...13,938,427
Ensembl chrNW_004955457:13,624,413...14,076,261 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 ISO protein:decreased expression:myocardium RGD PMID:19299913 RGD:5133278 NCBI chrNW_004955425:2,258,554...2,267,699
Ensembl chrNW_004955425:2,258,392...2,267,878 		JBrowse link
G Anxa1 annexin A1 treatment ISO protein:increased expression:heart, leukocyte RGD PMID:11641252 PMID:22924634 RGD:2306910 RGD:7421655 NCBI chrNW_004955512:5,686,508...5,703,645 JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 ISO protein:altered localization:cytoplasm RGD PMID:17602955 RGD:2315672 NCBI chrNW_004955550:1,273,170...1,275,843
Ensembl chrNW_004955550:1,273,284...1,279,743 		JBrowse link
G Arrb2 arrestin beta 2 ISO RGD PMID:29016703 RGD:13506827 NCBI chrNW_004955467:10,109,985...10,118,687
Ensembl chrNW_004955467:10,110,003...10,123,022 		JBrowse link
G Atf3 activating transcription factor 3 ISO RGD PMID:11485922 RGD:7327201 NCBI chrNW_004955406:4,875,672...4,889,173
Ensembl chrNW_004955406:4,875,613...4,889,242 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29702141 NCBI chrNW_004955435:19,537,224...19,563,631
Ensembl chrNW_004955435:19,536,634...19,564,580 		JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 ISO RGD PMID:17630344 RGD:13782075 NCBI chrNW_004955493:6,559,995...6,578,461
Ensembl chrNW_004955493:6,559,995...6,578,461 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 treatment ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:10734148 PMID:28637456 RGD:13782080 NCBI chrNW_004955482:7,233,336...7,295,754
Ensembl chrNW_004955482:7,233,336...7,295,754 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment ISO protein:decreased expression:myocardium (rat) RGD PMID:25305180 PMID:26109848 RGD:13792666 RGD:13792676 NCBI chrNW_004955495:6,664,394...6,666,693
Ensembl chrNW_004955495:6,664,394...6,666,693 		JBrowse link
G Bad BCL2 associated agonist of cell death treatment ISO protein:increased expression, decreased serine phosphorylation:heart RGD PMID:15339931 PMID:23364609 RGD:10053674 RGD:2292700 NCBI chrNW_004955422:20,795,585...20,809,039
Ensembl chrNW_004955422:20,795,676...20,809,245 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20026869 PMID:21223820 PMID:25547710 PMID:31583047 RGD:10054103 RGD:13782178 RGD:155230831 NCBI chrNW_004955559:1,695,960...1,700,246
Ensembl chrNW_004955559:1,695,960...1,700,244 		JBrowse link
G Bcl2 BCL2 apoptosis regulator treatment ISO RGD PMID:16289365 PMID:20821058 PMID:23364609 PMID:31583047 RGD:10053674 RGD:11561911 RGD:155230831 RGD:1599484 NCBI chrNW_004955402:46,911,125...47,084,214
Ensembl chrNW_004955402:46,916,266...47,084,485 		JBrowse link
G Bcl2l1 BCL2 like 1 treatment ISO RGD PMID:12668130 RGD:11035287 NCBI chrNW_004955422:29,254,440...29,307,104
Ensembl chrNW_004955422:29,254,216...29,308,174 		JBrowse link
G Becn1 beclin 1 treatment ISO RGD PMID:20812860 PMID:20821058 RGD:11561911 RGD:11561944 NCBI chrNW_004955451:16,616,595...16,625,731
Ensembl chrNW_004955451:16,616,595...16,625,730 		JBrowse link
G Bid BH3 interacting domain death agonist ISO protein:increased cleavage:heart: RGD PMID:11934844 PMID:19940077 RGD:13782263 RGD:2317561 NCBI chrNW_004955454:5,776,656...5,785,500
Ensembl chrNW_004955454:5,777,667...5,783,118 		JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase ISO mRNA:increased expression:left ventricle (rat) RGD PMID:17562528 RGD:1642307 NCBI chrNW_004955403:52,825,397...52,874,007
Ensembl chrNW_004955403:52,832,604...52,874,264 		JBrowse link
G Bnip3 BCL2 interacting protein 3 treatment ISO protein:decreased expression:myocardium (human) RGD PMID:16645637 PMID:28661226 RGD:11561983 RGD:155260328 NCBI chrNW_004955477:9,621,812...9,630,406
Ensembl chrNW_004955477:9,621,812...9,638,099 		JBrowse link
G Brd4 bromodomain containing 4 ISO mRNA,protein:increased expression:heart RGD PMID:33982231 RGD:155883171 NCBI chrNW_004955495:7,959,033...7,989,216
Ensembl chrNW_004955495:7,957,510...7,988,498 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 ISO mRNA:increased expression:heart RGD PMID:12909328 RGD:2289075 NCBI chrNW_004955406:39,303,221...39,307,308
Ensembl chrNW_004955406:39,303,175...39,308,778 		JBrowse link
G C3 complement C3 ISO protein:increased expression:myocardium RGD PMID:11560858 RGD:1582136 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697 		JBrowse link
G Casp3 caspase 3 ameliorates
treatment		 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14998631 PMID:18470603 PMID:29538428 PMID:30259997 RGD:13782276 RGD:2293314 RGD:329337366 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G Casp7 caspase 7 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14998631 PMID:29538428 RGD:13782276 NCBI chrNW_004955431:18,685,408...18,723,221
Ensembl chrNW_004955431:18,686,190...18,723,524 		JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte 		CTD
RGD		 PMID:11934844 PMID:14998631 RGD:13782263 NCBI chrNW_004955403:322,082...348,591
Ensembl chrNW_004955403:322,555...347,053 		JBrowse link
G Casp9 caspase 9 ameliorates
treatment		 ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte,endothelial cell		 CTD
RGD		 PMID:11934844 PMID:14998631 PMID:29538428 PMID:30259997 RGD:13782263 RGD:13782276 RGD:329337366 NCBI chrNW_004955527:2,613,691...2,630,217
Ensembl chrNW_004955527:2,613,683...2,629,738 		JBrowse link
G Casr calcium sensing receptor ISO protein:increased expression:ventricular myocardium (rat) RGD PMID:21766206 RGD:7205698 NCBI chrNW_004955427:21,486,608...21,574,017
Ensembl chrNW_004955427:21,486,427...21,575,210 		JBrowse link
G Cast calpastatin ameliorates ISO human transcript overexpression in rat model RGD PMID:12482022 PMID:14519437 RGD:405101692 RGD:5683872 NCBI chrNW_004955418:15,859,951...15,974,141
Ensembl chrNW_004955418:15,862,729...15,916,169 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: therapeutic RGD
CTD		 PMID:11510883 PMID:21600015 RGD:1581149 NCBI chrNW_004955422:11,783,973...11,826,970
Ensembl chrNW_004955422:11,781,835...11,827,464 		JBrowse link
G Cbl Cbl proto-oncogene severity ISO RGD PMID:24583314 RGD:11251947 NCBI chrNW_004955412:20,307,011...20,388,539
Ensembl chrNW_004955412:20,307,011...20,388,539 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO protein:decreased expression:monocyte: RGD PMID:15786508 RGD:4892017 NCBI chrNW_004955420:25,641,184...25,664,413 JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator treatment ISO RGD PMID:18466417 RGD:11341714 NCBI chrNW_004955403:415,092...442,214
Ensembl chrNW_004955403:412,632...434,741 		JBrowse link
G Cnr1 cannabinoid receptor 1 ISO RGD PMID:18771032 RGD:2316217 NCBI chrNW_004955411:15,052,151...15,077,320
Ensembl chrNW_004955411:15,052,163...15,077,320 		JBrowse link
G Cnr2 cannabinoid receptor 2 ISO RGD PMID:17950273 RGD:2316224 NCBI chrNW_004955452:3,763,742...3,795,069
Ensembl chrNW_004955452:3,763,742...3,795,069 		JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34355838 NCBI chrNW_004955449:9,340,716...9,400,049
Ensembl chrNW_004955449:9,340,716...9,404,308 		JBrowse link
G Crebbp CREB binding protein treatment ISO RGD PMID:24338162 RGD:153352322 NCBI chrNW_004955442:13,559,496...13,691,913
Ensembl chrNW_004955442:13,559,496...13,692,004 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO protein:decreased expression:blood, monocyte RGD PMID:15786508 RGD:4892017 NCBI chrNW_004955427:24,691,206...24,705,599
Ensembl chrNW_004955427:24,701,073...24,707,230 		JBrowse link
G Diablo diablo IAP-binding mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:14998631 NCBI chrNW_004955482:6,354,502...6,364,424
Ensembl chrNW_004955482:6,354,146...6,365,344 		JBrowse link
G Dnm1l dynamin 1 like ameliorates ISO RGD PMID:30259997 RGD:329337366 NCBI chrNW_004955505:3,025,742...3,081,491
Ensembl chrNW_004955505:3,023,018...3,081,680 		JBrowse link
G Ece1 endothelin converting enzyme 1 ISO RGD PMID:12193087 PMID:18586023 RGD:4892580 RGD:7244160 NCBI chrNW_004955452:1,653,783...1,704,619
Ensembl chrNW_004955452:1,651,316...1,751,489 		JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15642760 PMID:16700825 PMID:18586023 RGD:4892580 NCBI chrNW_004955465:2,287,906...2,314,945
Ensembl chrNW_004955465:2,287,798...2,314,753 		JBrowse link
G Ednra endothelin receptor type A ISO RGD PMID:18586023 RGD:4892580 NCBI chrNW_004955428:3,062,303...3,114,761
Ensembl chrNW_004955428:3,062,303...3,114,761 		JBrowse link
G Ednrb endothelin receptor type B ISO RGD PMID:21048781 RGD:4892332 NCBI chrNW_004955404:29,394,253...29,425,358
Ensembl chrNW_004955404:29,394,164...29,425,358 		JBrowse link
G Egln1 egl-9 family hypoxia inducible factor 1 susceptibility ISO RGD PMID:20185832 RGD:11251775 NCBI chrNW_004955492:7,407,800...7,454,851
Ensembl chrNW_004955492:7,407,800...7,454,842 		JBrowse link
G Ephx2 epoxide hydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19834332 NCBI chrNW_004955403:49,999,563...50,038,800
Ensembl chrNW_004955403:49,999,563...50,041,572 		JBrowse link
G Esr1 estrogen receptor 1 ISO RGD PMID:18314151 RGD:4892299 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353 		JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:18656630 RGD:5508820 NCBI chrNW_004955466:5,587,003...5,644,765
Ensembl chrNW_004955466:5,575,088...5,638,946 		JBrowse link
G Fadd Fas associated via death domain treatment ISO RGD PMID:26038570 PMID:26948086 RGD:11341801 RGD:13792504 NCBI chrNW_004955422:16,026,323...16,035,808
Ensembl chrNW_004955422:16,031,280...16,036,281 		JBrowse link
G Fas Fas cell surface death receptor treatment ISO RGD PMID:21316771 RGD:8686424 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455 		JBrowse link
G Fis1 fission, mitochondrial 1 ameliorates ISO RGD PMID:30259997 RGD:329337366 NCBI chrNW_004955456:16,057,158...16,060,623
Ensembl chrNW_004955456:16,038,221...16,060,623 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase treatment ISO RGD PMID:27129213 RGD:11574725 NCBI chrNW_004955413:4,162,467...4,166,783
Ensembl chrNW_004955413:4,162,467...4,166,783 		JBrowse link
G Gcg glucagon treatment ISO RGD PMID:24125539 RGD:10402369 NCBI chrNW_004955449:11,708,152...11,716,429
Ensembl chrNW_004955449:11,708,152...11,716,429 		JBrowse link
G Gdf11 growth differentiation factor 11 ISO mRNA, protein:decreased expression:heart (mouse) RGD PMID:30765322 RGD:329849112 NCBI chrNW_004955458:3,388,402...3,398,040
Ensembl chrNW_004955458:3,388,402...3,398,040 		JBrowse link
G Gja1 gap junction protein alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17445419 NCBI chrNW_004955436:3,612,533...3,618,095
Ensembl chrNW_004955436:3,612,533...3,618,095 		JBrowse link
G Glrx glutaredoxin ISO mRNA:decreased expression:heart: RGD PMID:18163565 RGD:2306160 NCBI chrNW_004955418:16,747,709...16,754,718
Ensembl chrNW_004955418:16,747,776...16,752,858 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO RGD PMID:11043918 RGD:401827843 NCBI chrNW_004955408:2,622,162...2,629,088
Ensembl chrNW_004955408:2,622,741...2,629,032 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment
severity
susceptibility		 ISO protein:increased expression:heart, mitochondrion (mouse)
associated with Hypertension
associated with Diabetes Mellitus, Experimental		 RGD PMID:23467820 PMID:24170934 PMID:27296507 PMID:27601479 PMID:27865836 RGD:13513990 RGD:13513993 RGD:13513995 RGD:13792704 RGD:13792779 NCBI chrNW_004955422:18,173,438...18,192,357
Ensembl chrNW_004955422:18,170,616...18,192,412 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment ISO RGD PMID:20217242 PMID:26918336 PMID:29978610 RGD:13792725 RGD:13792772 RGD:5509104 NCBI chrNW_004955427:19,489,972...19,671,137
Ensembl chrNW_004955427:19,495,422...19,671,137 		JBrowse link
G Gsr glutathione-disulfide reductase treatment ISO RGD PMID:24769323 RGD:10401892 NCBI chrNW_004955463:7,130,459...7,153,631
Ensembl chrNW_004955463:7,131,364...7,153,583 		JBrowse link
G Hdac3 histone deacetylase 3 ameliorates ISO RGD PMID:33982231 RGD:155883171 NCBI chrNW_004955415:12,138,520...12,154,234
Ensembl chrNW_004955415:12,138,870...12,154,234 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment ISO mRNA:increased expression:heart
CTD Direct Evidence: marker/mechanism
protein:increased expression:myocardium		 RGD
CTD		 PMID:12189448 PMID:18549825 PMID:19727523 PMID:20170615 PMID:22050707 RGD:1626327 RGD:5147885 RGD:9068872 NCBI chrNW_004955466:8,000,311...8,022,497
Ensembl chrNW_004955466:8,000,044...8,022,497 		JBrowse link
G Hmgb1 high mobility group box 1 treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19540007 PMID:21113057 PMID:23531454 RGD:10402066 RGD:10402170 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339 		JBrowse link
G Hmox1 heme oxygenase 1 treatment ISO RGD PMID:12709584 PMID:22179023 PMID:23921302 RGD:10755573 RGD:10755585 RGD:1598392 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979 		JBrowse link
G Hrh2 histamine receptor H2 susceptibility ISO RGD PMID:23467745 RGD:9685524 NCBI chrNW_004955408:28,186,316...28,225,146
Ensembl chrNW_004955408:28,186,249...28,229,411 		JBrowse link
G Hrh3 histamine receptor H3 ISO RGD PMID:15076218 RGD:1626433 NCBI chrNW_004955528:1,819,247...1,826,707
Ensembl chrNW_004955528:1,819,247...1,826,707 		JBrowse link
G Hsf1 heat shock transcription factor 1 ISO RGD PMID:22426029 RGD:10402789 NCBI chrNW_004955454:2,907,265...2,932,352
Ensembl chrNW_004955454:2,907,265...2,932,351 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment ISO RGD PMID:24129401 PMID:25547710 RGD:11354962 RGD:13782178 NCBI chrNW_004955419:3,055,420...3,060,208
Ensembl chrNW_004955419:3,055,420...3,062,131 		JBrowse link
G Htra2 HtrA serine peptidase 2 ISO protein:increased expression:myocardium, cytosol (mouse) RGD PMID:15611365 RGD:5688376 NCBI chrNW_004955424:11,255,756...11,259,170
Ensembl chrNW_004955424:11,255,756...11,259,170 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:heart (rat)
CTD Direct Evidence: marker/mechanism		 RGD
CTD		 PMID:12087064 PMID:20851484 RGD:4145348 NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755 		JBrowse link
G Il10 interleukin 10 treatment ISO protein:increased expression:plasma RGD PMID:19275881 PMID:23840272 RGD:2311056 RGD:7365001 NCBI chrNW_004955406:42,307,789...42,312,255
Ensembl chrNW_004955406:42,307,664...42,312,779 		JBrowse link
G Il17a interleukin 17A treatment ISO RGD PMID:22030025 RGD:9068944 NCBI chrNW_004955411:5,896,435...5,899,911
Ensembl chrNW_004955411:5,896,702...5,900,962 		JBrowse link
G Il18 interleukin 18 ISO RGD PMID:19164288 PMID:19805173 RGD:4889400 RGD:4889578 NCBI chrNW_004955412:13,807,361...13,826,007
Ensembl chrNW_004955412:13,806,553...13,825,634 		JBrowse link
G Il18bp interleukin 18 binding protein ISO mRNA:increased expression:heart RGD PMID:19164288 PMID:19805173 RGD:4889400 RGD:4889578 NCBI chrNW_004955414:19,327,828...19,332,577 JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO RGD PMID:19164288 RGD:4889578 NCBI chrNW_004955470:7,894,900...7,923,653
Ensembl chrNW_004955470:7,893,329...7,923,744 		JBrowse link
G Il1a interleukin 1 alpha treatment ISO RGD PMID:7622355 PMID:8576926 RGD:7794741 RGD:7794764 NCBI chrNW_004955470:1,527,710...1,538,418
Ensembl chrNW_004955470:1,527,674...1,538,466 		JBrowse link
G Il1b interleukin 1 beta treatment ISO mRNA:increased expression:heart RGD PMID:17134725 PMID:31583047 RGD:155230831 RGD:1626628 NCBI chrNW_004955470:1,486,936...1,491,888
Ensembl chrNW_004955470:1,486,967...1,491,947 		JBrowse link
G Il1rl2 interleukin 1 receptor like 2 ISO compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chrNW_004955470:7,703,369...7,742,058
Ensembl chrNW_004955470:7,704,134...7,742,064 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein RGD PMID:22649318 RGD:7174360 NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471 		JBrowse link
G Il36rn interleukin 36 receptor antagonist ISO RGD PMID:32048631 RGD:126925167 NCBI chrNW_004955470:1,209,389...1,214,730
Ensembl chrNW_004955470:1,209,325...1,214,821 		JBrowse link
G Il6 interleukin 6 treatment ISO RGD PMID:27087891 PMID:31583047 RGD:11062149 RGD:155230831 NCBI chrNW_004955410:25,079,835...25,084,390 JBrowse link
G Il6r interleukin 6 receptor ISO RGD PMID:16056242 RGD:1625435 NCBI chrNW_004955545:932,814...979,359
Ensembl chrNW_004955545:950,765...981,762 		JBrowse link
G Inhba inhibin subunit beta A ISO mRNA, protein:increased expression:heart (mouse) RGD PMID:30765322 RGD:329849112 NCBI chrNW_004955460:2,054,879...2,066,628
Ensembl chrNW_004955460:2,046,588...2,066,609 		JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 ISO protein:increased activity:ventricle myocardium (rat) RGD PMID:15793310 RGD:1579809 NCBI chrNW_004955580:663,651...668,622
Ensembl chrNW_004955580:661,609...668,622 		JBrowse link
G Irf9 interferon regulatory factor 9 exacerbates
ameliorates		 ISO protein:increased expression:left ventricular free wall RGD PMID:25150882 RGD:125093742 NCBI chrNW_004955409:36,233,633...36,239,916
Ensembl chrNW_004955409:36,234,077...36,239,500 		JBrowse link
G Jak2 Janus kinase 2 treatment ISO associated with Diabetes Mellitus, Experimental RGD PMID:23747931 PMID:23796350 RGD:10403071 RGD:8694332 NCBI chrNW_004955434:9,227,897...9,341,208
Ensembl chrNW_004955434:9,227,595...9,341,208 		JBrowse link
G Kcnj11 potassium inwardly rectifying channel subfamily J member 11 ISO RGD PMID:17906066 RGD:7297046 NCBI chrNW_004955414:32,209,426...32,212,424
Ensembl chrNW_004955414:32,210,545...32,211,717 		JBrowse link
G Kcnj8 potassium inwardly rectifying channel subfamily J member 8 ISO RGD PMID:12234964 RGD:729109 NCBI chrNW_004955413:17,364,447...17,371,255
Ensembl chrNW_004955413:17,364,213...17,371,255 		JBrowse link
G Kng1 kininogen 1 ISO CTD Direct Evidence: therapeutic CTD PMID:2535056 PMID:7856280 NCBI chrNW_004955420:20,989,197...21,016,084 JBrowse link
G Lep leptin ISO RGD PMID:21122204 RGD:5128547 NCBI chrNW_004955479:9,266,604...9,276,568
Ensembl chrNW_004955479:9,274,516...9,279,472 		JBrowse link
G Lepr leptin receptor ISO mRNA:decreased expression:heart
mRNA:altered expression:heart		 RGD PMID:15284063 PMID:17134725 RGD:1626628 RGD:5129123 NCBI chrNW_004955423:25,108,897...25,185,315
Ensembl chrNW_004955423:25,111,266...25,185,407 		JBrowse link
G LOC102012042 cytochrome b-245 heavy chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:19207477 NCBI chrNW_004955587:781,533...818,149
Ensembl chrNW_004955587:781,388...819,912 		JBrowse link
G LOC102025775 histone H2AX treatment ISO RGD PMID:23108649 RGD:8693739 NCBI chrNW_004955412:20,203,173...20,204,714
Ensembl chrNW_004955412:20,203,772...20,204,203 		JBrowse link
G Lum lumican ISO RGD PMID:11348051 RGD:1582122 NCBI chrNW_004955405:28,299,966...28,307,982
Ensembl chrNW_004955405:28,298,988...28,308,054 		JBrowse link
G Map1lc3a microtubule associated protein 1 light chain 3 alpha treatment ISO protein:increased expression:heart RGD PMID:20812860 PMID:20821058 RGD:11561911 RGD:11561944 NCBI chrNW_004955422:26,774,466...26,776,024
Ensembl chrNW_004955422:26,774,922...26,775,884 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO RGD PMID:14749328 PMID:15492008 RGD:1582277 RGD:7495840 NCBI chrNW_004955478:3,331,607...3,448,840
Ensembl chrNW_004955478:3,331,607...3,448,842 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment ISO RGD PMID:31583047 RGD:155230831 NCBI chrNW_004955439:162,499...376,919
Ensembl chrNW_004955439:163,103...377,808 		JBrowse link
G Mapk1 mitogen-activated protein kinase 1 treatment ISO RGD PMID:15653762 PMID:25345742 RGD:13800900 RGD:1582282 NCBI chrNW_004955442:17,284,232...17,380,026
Ensembl chrNW_004955442:17,284,232...17,380,020 		JBrowse link
G Mapk14 mitogen-activated protein kinase 14 ISO RGD PMID:14749328 RGD:7495840 NCBI chrNW_004955437:3,836,331...3,884,083
Ensembl chrNW_004955437:3,838,232...3,884,083 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 treatment ISO RGD PMID:25345742 PMID:28814571 PMID:29741915 RGD:13800564 RGD:13800874 RGD:13800900 NCBI chrNW_004955493:6,870,699...6,876,836
Ensembl chrNW_004955493:6,869,668...6,879,152 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 treatment ISO RGD PMID:12883833 PMID:15309413 PMID:31583047 RGD:155230831 RGD:1582311 RGD:1582312 NCBI chrNW_004955556:1,593,552...1,705,543
Ensembl chrNW_004955556:1,593,494...1,665,784 		JBrowse link
G Mb myoglobin ISO RGD PMID:11972171 PMID:15132981 RGD:1582385 RGD:1582431 NCBI chrNW_004955405:43,215,404...43,221,606
Ensembl chrNW_004955405:43,215,007...43,222,052 		JBrowse link
G Mbl2 mannose binding lectin 2 treatment ISO RGD PMID:25482922 RGD:11530049 NCBI chrNW_004955425:7,704,371...7,708,951
Ensembl chrNW_004955425:7,702,137...7,709,006 		JBrowse link
G Mdm2 MDM2 proto-oncogene ISO protein:increased serine phosphorylation:heart ventricle (rat) RGD PMID:14644432 RGD:2317401 NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808 		JBrowse link
G Mfn2 mitofusin 2 treatment ISO RGD PMID:24721408 RGD:13204835 NCBI chrNW_004955486:1,937,873...1,962,577
Ensembl chrNW_004955486:1,937,802...1,962,772 		JBrowse link
G Mki67 marker of proliferation Ki-67 ISO RGD PMID:22405128 RGD:6483543 NCBI chrNW_004955477:5,847,288...5,875,970 JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment ISO RGD PMID:16699069 PMID:23889688 RGD:1582614 RGD:8657084 NCBI chrNW_004955433:13,024,844...13,050,041
Ensembl chrNW_004955433:13,024,418...13,052,775 		JBrowse link
G Mstn myostatin ISO mRNA, protein:increased expression:heart (mouse) RGD PMID:30765322 RGD:329849112 NCBI chrNW_004955403:8,914,505...8,921,190
Ensembl chrNW_004955403:8,914,482...8,923,465 		JBrowse link
G Myd88 MYD88 innate immune signal transduction adaptor ISO RGD PMID:14962484 RGD:1302746 NCBI chrNW_004955427:25,553,589...25,557,654
Ensembl chrNW_004955427:25,553,589...25,559,138 		JBrowse link
G Ncl nucleolin ISO protein:decreased expression:heart RGD PMID:23594402 RGD:9686384 NCBI chrNW_004955453:4,154,627...4,164,253
Ensembl chrNW_004955453:4,154,627...4,164,253 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 treatment ISO RGD PMID:21700931 RGD:13801200 NCBI chrNW_004955457:8,838,216...8,879,059
Ensembl chrNW_004955457:8,838,216...8,883,481 		JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 treatment ISO RGD PMID:20501665 RGD:10003160 NCBI chrNW_004955451:13,088,680...13,099,839
Ensembl chrNW_004955451:13,088,906...13,099,839 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO RGD PMID:24915518 RGD:10412738 NCBI chrNW_004955403:19,510,122...19,536,428
Ensembl chrNW_004955403:19,532,103...19,535,944 		JBrowse link
G Nfkbia NFKB inhibitor alpha treatment ISO RGD PMID:19304943 RGD:10413871 NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO mRNA:decreased expression:heart (rat)
CTD Direct Evidence: marker/mechanism|therapeutic		 RGD
CTD		 PMID:12003803 PMID:12087064 PMID:14990356 PMID:19207477 PMID:20828608 More... RGD:5509098 NCBI chrNW_004955481:5,197,957...5,232,406
Ensembl chrNW_004955481:5,201,234...5,231,961 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:12354446 PMID:18390819 PMID:20828747 PMID:29274587 PMID:29299201 RGD:13503347 RGD:13504684 RGD:2292091 RGD:4891991 NCBI chrNW_004955491:5,438,228...5,457,308
Ensembl chrNW_004955491:5,438,010...5,460,814 		JBrowse link
G Nox1 NADPH oxidase 1 ISO mRNA:increased expression:heart RGD PMID:33658472 RGD:329955358 NCBI chrNW_004955503:6,973,965...7,020,182
Ensembl chrNW_004955503:6,974,239...6,997,618 		JBrowse link
G Nppb natriuretic peptide B ISO RGD PMID:21168723 RGD:5685663 NCBI chrNW_004955486:2,054,775...2,056,130 JBrowse link
G Nppc natriuretic peptide C ISO RGD PMID:15337698 RGD:1580149 NCBI chrNW_004955453:3,884,580...3,888,494
Ensembl chrNW_004955453:3,884,560...3,888,850 		JBrowse link
G Npr3 natriuretic peptide receptor 3 ISO RGD PMID:15337698 RGD:1580149 NCBI chrNW_004955426:18,491,350...18,559,299
Ensembl chrNW_004955426:18,491,350...18,553,743 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 ISO mRNA:decreased expression:heart left ventricle RGD PMID:17562528 RGD:1642307 NCBI chrNW_004955403:41,681,834...41,693,094
Ensembl chrNW_004955403:41,681,728...41,694,020 		JBrowse link
G Oprd1 opioid receptor delta 1 ISO RGD PMID:12136724 RGD:2316590 NCBI chrNW_004955452:7,866,790...7,913,399
Ensembl chrNW_004955452:7,866,758...7,913,399 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO RGD PMID:20431845 RGD:6480645 NCBI chrNW_004955448:2,442,368...2,488,567
Ensembl chrNW_004955448:2,442,368...2,488,567 		JBrowse link
G Parp1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:9670921 PMID:23598272 RGD:11073735 RGD:5683917 NCBI chrNW_004955489:520,875...557,609
Ensembl chrNW_004955489:520,875...557,615 		JBrowse link
G Pawr pro-apoptotic WT1 regulator treatment ISO RGD PMID:18055876 RGD:9835369 NCBI chrNW_004955405:18,434,711...18,540,710
Ensembl chrNW_004955405:18,434,711...18,540,710 		JBrowse link
G Pdia3 protein disulfide isomerase family A member 3 ISO RGD PMID:12872233 RGD:1624250 NCBI chrNW_004955416:10,197,957...10,221,104
Ensembl chrNW_004955416:10,198,099...10,220,792 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:8989147 RGD:2311662 NCBI chrNW_004955478:7,448,584...7,531,860
Ensembl chrNW_004955478:7,478,492...7,531,188 		JBrowse link
G Phlda3 pleckstrin homology like domain family A member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34351043 NCBI chrNW_004955406:37,579,006...37,582,230
Ensembl chrNW_004955406:37,579,006...37,582,230 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:20179753 RGD:6482687 NCBI chrNW_004955410:11,402,476...11,433,335
Ensembl chrNW_004955410:11,402,520...11,437,422 		JBrowse link
G Plcd1 phospholipase C delta 1 ISO protein:altered activity RGD PMID:12623065 RGD:1304368 NCBI chrNW_004955421:4,856,366...4,880,309
Ensembl chrNW_004955421:4,856,366...4,880,309 		JBrowse link
G Pld2 phospholipase D2 ISO protein:altered activity:sarcolemma, sarcoplasmic reticulum, heart left ventricle RGD PMID:15752718 RGD:2299906 NCBI chrNW_004955467:10,239,177...10,250,516
Ensembl chrNW_004955467:10,239,177...10,250,890 		JBrowse link
G Pln phospholamban treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10734148 PMID:21934351 RGD:7327186 NCBI chrNW_004955436:1,439,098...1,447,070
Ensembl chrNW_004955436:1,439,098...1,447,070 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: therapeutic CTD PMID:16411023 NCBI chrNW_004955413:30,306,563...30,366,245
Ensembl chrNW_004955413:30,307,219...30,359,500 		JBrowse link
G Ppard peroxisome proliferator activated receptor delta ISO RGD PMID:19997057 RGD:2324876 NCBI chrNW_004955437:3,285,281...3,354,099
Ensembl chrNW_004955437:3,288,830...3,357,048 		JBrowse link
G Pparg peroxisome proliferator activated receptor gamma ISO RGD PMID:18562925 RGD:2301853 NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha treatment ISO RGD PMID:19096023 RGD:10059669 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 treatment ISO RGD PMID:20501665 RGD:10003160 NCBI chrNW_004955464:2,996,608...3,062,197
Ensembl chrNW_004955464:3,003,837...3,062,197 		JBrowse link
G Prkcb protein kinase C beta ISO RGD PMID:15878997 RGD:1625520 NCBI chrNW_004955493:2,395,494...2,710,522
Ensembl chrNW_004955493:2,395,109...2,710,934 		JBrowse link
G Prkcd protein kinase C delta ISO protein:decreased expression:heart RGD PMID:17322024 RGD:1642542 NCBI chrNW_004955430:3,125,066...3,151,857
Ensembl chrNW_004955430:3,124,738...3,153,274 		JBrowse link
G Prkd1 protein kinase D1 ameliorates ISO RGD PMID:24345679 RGD:307727199 NCBI chrNW_004955409:30,554,095...30,860,588
Ensembl chrNW_004955409:30,554,013...30,860,649 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 treatment ISO RGD PMID:18332860 PMID:19845676 RGD:7777120 RGD:7777130 NCBI chrNW_004955425:6,176,335...7,335,867
Ensembl chrNW_004955425:6,176,432...7,331,446 		JBrowse link
G Procr protein C receptor treatment ISO RGD PMID:26994471 RGD:13515126 NCBI chrNW_004955422:26,215,757...26,220,396
Ensembl chrNW_004955422:26,216,002...26,220,101 		JBrowse link
G Pten phosphatase and tensin homolog treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19038262 PMID:20951693 RGD:127285611 NCBI chrNW_004955425:5,007,811...5,091,829
Ensembl chrNW_004955425:5,014,147...5,091,829 		JBrowse link
G Ptger3 prostaglandin E receptor 3 treatment ISO RGD PMID:10193764 RGD:10043342 NCBI chrNW_004955423:21,096,926...21,164,435 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:17660401 RGD:2300261 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family treatment ISO RGD PMID:20501665 RGD:10003160 NCBI chrNW_004955435:15,090,521...15,171,397
Ensembl chrNW_004955435:15,150,827...15,171,397 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit treatment ISO protein:altered localization:nucleus RGD PMID:18636044 PMID:31583047 RGD:155230831 RGD:2298773 NCBI chrNW_004955422:19,602,930...19,612,263
Ensembl chrNW_004955422:19,603,345...19,611,516 		JBrowse link
G Rhoa ras homolog family member A ISO protein:altered localization:heart RGD PMID:17322412 RGD:1642967 NCBI chrNW_004955532:1,300,821...1,347,453
Ensembl chrNW_004955532:1,300,462...1,347,451 		JBrowse link
G Rnf41 ring finger protein 41 severity ISO RGD PMID:21312039 RGD:401827146 NCBI chrNW_004955458:3,799,450...3,833,269
Ensembl chrNW_004955458:3,799,450...3,833,263 		JBrowse link
G Rnls renalase, FAD dependent amine oxidase ISO RGD PMID:21178975 RGD:7327174 NCBI chrNW_004955425:4,368,620...4,667,947 JBrowse link
G S100b S100 calcium binding protein B ISO mRNA, protein:increased expression:myocardium RGD PMID:21663912 RGD:5508825 NCBI chrNW_004955407:42,972,584...42,980,510
Ensembl chrNW_004955407:42,972,584...42,980,510 		JBrowse link
G Selp selectin P ISO CTD Direct Evidence: marker/mechanism RGD
CTD		 PMID:12087064 PMID:21146547 RGD:6480105 NCBI chrNW_004955462:7,658,371...7,692,870
Ensembl chrNW_004955462:7,652,437...7,693,994 		JBrowse link
G Serpina3 serpin family A member 3 ISO RGD PMID:7562495 RGD:5147423 NCBI chrNW_004955438:17,758,763...17,766,113
Ensembl chrNW_004955438:17,758,718...17,766,180 		JBrowse link
G Serpine1 serpin family E member 1 treatment ISO RGD PMID:26958805 RGD:11073621 NCBI chrNW_004955456:16,147,523...16,157,040
Ensembl chrNW_004955456:16,145,944...16,157,142 		JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:16942749 RGD:8661647 NCBI chrNW_004955511:2,545,337...2,557,850
Ensembl chrNW_004955511:2,545,285...2,557,982 		JBrowse link
G Sfrp2 secreted frizzled related protein 2 ISO RGD PMID:19109969 RGD:4107088 NCBI chrNW_004955471:8,103,937...8,112,596
Ensembl chrNW_004955471:8,103,783...8,112,321 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 ISO RGD PMID:25628389 RGD:12904914 NCBI chrNW_004955482:8,079,905...8,100,791
Ensembl chrNW_004955482:8,096,160...8,097,765 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO protein:increased expression:heart RGD PMID:18228117 RGD:2306299 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21060073 NCBI chrNW_004955425:20,280,725...20,307,663
Ensembl chrNW_004955425:20,279,963...20,307,663 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 treatment ISO RGD PMID:24126566 RGD:9681554 NCBI chrNW_004955403:23,878,329...23,882,322
Ensembl chrNW_004955403:23,878,329...23,882,322 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 ISO RGD PMID:10336852 RGD:12879857 NCBI chrNW_004955537:2,408,042...2,438,788
Ensembl chrNW_004955537:2,408,042...2,439,511 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 ISO RGD PMID:10336852 RGD:12879857 NCBI chrNW_004955467:9,630,304...9,636,005
Ensembl chrNW_004955467:9,630,304...9,636,005 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiac muscle cell		 CTD
RGD		 PMID:15215644 PMID:17267548 PMID:17822695 RGD:1642716 RGD:1642729 NCBI chrNW_004955441:7,653,107...8,037,784
Ensembl chrNW_004955441:7,656,031...7,957,640 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 ISO RGD PMID:22803959 RGD:6771238 NCBI chrNW_004955452:6,409,833...6,467,841
Ensembl chrNW_004955452:6,409,833...6,467,841 		JBrowse link
G Smad1 SMAD family member 1 ISO RGD PMID:15911698 RGD:1643233 NCBI chrNW_004955428:1,357,398...1,429,521
Ensembl chrNW_004955428:1,361,085...1,429,948 		JBrowse link
G Smad3 SMAD family member 3 treatment ISO RGD PMID:22913380 RGD:12903950 NCBI chrNW_004955450:8,747,651...8,842,003
Ensembl chrNW_004955450:8,747,651...8,842,136 		JBrowse link
G Smad4 SMAD family member 4 treatment ISO RGD PMID:22913380 RGD:12903950 NCBI chrNW_004955402:35,956,080...36,001,746
Ensembl chrNW_004955402:35,961,165...35,994,538 		JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO human protein in a rat model RGD PMID:12668130 PMID:19277497 PMID:23629152 RGD:11035287 RGD:8655884 RGD:8655965 NCBI chrNW_004955407:31,261,451...31,267,657
Ensembl chrNW_004955407:31,263,863...31,267,727 		JBrowse link
G Sod2 superoxide dismutase 2 treatment ISO RGD PMID:11864929 PMID:12668130 RGD:11035287 RGD:1581222 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163 		JBrowse link
G Sord sorbitol dehydrogenase ISO CTD Direct Evidence: marker/mechanism
protein:increased activity:heart		 CTD
RGD		 PMID:14525943 PMID:18549825 RGD:1601364 NCBI chrNW_004955409:8,305,819...8,333,733
Ensembl chrNW_004955409:8,303,602...8,333,869 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15165989 RGD:1581342 NCBI chrNW_004955474:1,914,477...1,922,025
Ensembl chrNW_004955474:1,913,829...1,922,016 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 ISO protein:increased phosphorylation:heart RGD PMID:16935931 RGD:1600091 NCBI chrNW_004955403:8,156,660...8,192,018
Ensembl chrNW_004955403:8,156,660...8,194,762 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment ISO RGD PMID:23796350 RGD:8694332 NCBI chrNW_004955451:16,320,326...16,348,505
Ensembl chrNW_004955451:16,319,904...16,357,687 		JBrowse link
G Tek TEK receptor tyrosine kinase ISO mRNA, protein:increased expression:ventricle myocardium RGD PMID:12737621 RGD:1601505 NCBI chrNW_004955472:7,633,790...7,748,130
Ensembl chrNW_004955472:7,633,721...7,748,386 		JBrowse link
G Tfrc transferrin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18549825 NCBI chrNW_004955420:12,348,392...12,372,714
Ensembl chrNW_004955420:12,348,821...12,372,691 		JBrowse link
G Tgfb1 transforming growth factor beta 1 treatment ISO RGD PMID:22913380 RGD:12903950 NCBI chrNW_004955555:274,405...288,441
Ensembl chrNW_004955555:270,652...288,441 		JBrowse link
G Thbs1 thrombospondin 1 ISO mRNA:increased expression:heart RGD PMID:16179730 RGD:2317960 NCBI chrNW_004955416:6,490,034...6,506,419
Ensembl chrNW_004955416:6,489,451...6,506,419 		JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 ISO protein:increased expression:blood RGD PMID:12707244 RGD:2290461 NCBI chrNW_004955429:14,689,016...14,693,211
Ensembl chrNW_004955429:14,685,031...14,693,211 		JBrowse link
G Tlr2 toll like receptor 2 ISO RGD PMID:19274437 RGD:2312688 NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258 		JBrowse link
G Tlr4 toll like receptor 4 ISO RGD PMID:14962484 RGD:1302746 NCBI chrNW_004955419:10,190,937...10,201,896
Ensembl chrNW_004955419:10,191,120...10,202,135 		JBrowse link
G Tnc tenascin C ISO RGD PMID:20554738 RGD:4889599 NCBI chrNW_004955419:12,569,620...12,662,897
Ensembl chrNW_004955419:12,569,547...12,662,958 		JBrowse link
G Tnf tumor necrosis factor treatment ISO protein:increased expression:serum, heart: RGD PMID:24157164 PMID:31583047 RGD:155230831 RGD:7387274 NCBI chrNW_004955437:117,267...119,899
Ensembl chrNW_004955437:117,206...120,700 		JBrowse link
G Tnni3 troponin I3, cardiac type ameliorates ISO RGD PMID:30259997 RGD:329337366 NCBI chrNW_004955567:1,037,325...1,042,102
Ensembl chrNW_004955567:1,037,462...1,042,039 		JBrowse link
G Tp53 tumor protein p53 ISO protein:increased expression:heart RGD PMID:18317410 RGD:2290554 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
G Txn2 thioredoxin 2 ISO mRNA, protein:decreased expression:heart RGD PMID:18045550 RGD:2306159 NCBI chrNW_004955413:23,044,866...23,056,017
Ensembl chrNW_004955413:23,041,559...23,056,018 		JBrowse link
G Ucn urocortin ISO RGD PMID:15806110 RGD:1642783 NCBI chrNW_004955469:9,277,637...9,278,641
Ensembl chrNW_004955469:9,277,637...9,278,641 		JBrowse link
G Ucp2 uncoupling protein 2 ISO mRNA:increased expression:myocardium RGD PMID:19526854 RGD:2313528 NCBI chrNW_004955414:17,592,914...17,596,477
Ensembl chrNW_004955414:17,592,914...17,596,477 		JBrowse link
G Ucp3 uncoupling protein 3 ISO mRNA:increased expression:myocardium RGD PMID:19526854 RGD:2313528 NCBI chrNW_004955414:17,558,889...17,578,108
Ensembl chrNW_004955414:17,558,889...17,578,737 		JBrowse link
G Uts2 urotensin 2 ISO RGD PMID:17900760 RGD:2306836 NCBI chrNW_004955486:5,052,045...5,056,610
Ensembl chrNW_004955486:5,052,045...5,056,610 		JBrowse link
G Uts2r urotensin 2 receptor ISO RGD PMID:17900760 RGD:2306836 NCBI chrNW_004955506:756,859...761,891 JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO protein:increased expression:heart RGD PMID:23052973 RGD:7207792 NCBI chrNW_004955435:5,390,745...5,410,025
Ensembl chrNW_004955435:5,390,751...5,411,691 		JBrowse link
G Vcan versican ISO mRNA:increased expression:heart RGD PMID:16311904 RGD:1598497 NCBI chrNW_004955418:26,967,595...27,078,430 JBrowse link
G Vdac1 voltage dependent anion channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25488258 NCBI chrNW_004955408:5,260,444...5,275,972
Ensembl chrNW_004955408:5,260,353...5,275,990 		JBrowse link
G Vdr vitamin D receptor ISO mRNA,protein:increased expression, activity:heart: RGD PMID:25365634 RGD:13432076 NCBI chrNW_004955500:6,745,725...6,798,052
Ensembl chrNW_004955500:6,745,678...6,798,048 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chrNW_004955437:9,527,445...9,541,908 JBrowse link
G Xiap X-linked inhibitor of apoptosis treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14998631 PMID:20501665 RGD:10003160 NCBI chrNW_004955473:10,823,795...10,878,256
Ensembl chrNW_004955473:10,827,435...10,840,604 		JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase ISO mRNA,protein:increased expression:myocardium (mouse) RGD PMID:30259997 RGD:329337366 NCBI chrNW_004955402:9,199,704...9,255,183
Ensembl chrNW_004955402:9,226,295...9,256,044 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14194
    disease of anatomical entity 13849
      cardiovascular system disease 4080
        heart disease 2858
          cardiomyopathy 1146
            Myocardial Reperfusion Injury 214
Path 2
Term Annotations click to browse term
  disease 14194
    disease of anatomical entity 13849
      cardiovascular system disease 4080
        vascular disease 2857
          ischemia 1283
            Myocardial Ischemia 794
              Myocardial Reperfusion Injury 214
paths to the root