Casp7 (caspase 7) - Rat Genome Database

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Gene: Casp7 (caspase 7) Chinchilla lanigera
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Symbol: Casp7
Name: caspase 7
RGD ID: 8914022
Description: ENCODES a protein that exhibits aspartic-type endopeptidase activity (ortholog); cysteine-type endopeptidase activity (ortholog); cysteine-type endopeptidase activity involved in apoptotic process (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to staurosporine (ortholog); PARTICIPATES IN extrinsic apoptotic pathway; FasL mediated signaling pathway; glutathione metabolic pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); acute myocardial infarction (ortholog); Alzheimer's disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: caspase 7, apoptosis-related cysteine peptidase; caspase-7
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543118,686,190 - 18,723,524 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543118,685,408 - 18,723,221 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Casp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543118,686,190 - 18,723,524 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543118,685,408 - 18,723,221 (+)NCBIChiLan1.0ChiLan1.0
CASP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810113,679,194 - 113,730,909 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10113,679,162 - 113,730,907 (+)EnsemblGRCh38hg38GRCh38
GRCh3710115,438,953 - 115,490,668 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610115,428,925 - 115,480,654 (+)NCBINCBI36Build 36hg18NCBI36
Build 3410115,428,952 - 115,480,652NCBI
Celera10109,166,297 - 109,218,022 (+)NCBICelera
Cytogenetic Map10q25.3NCBI
HuRef10109,065,803 - 109,118,487 (+)NCBIHuRef
CHM1_110115,720,952 - 115,772,694 (+)NCBICHM1_1
T2T-CHM13v2.010114,571,036 - 114,622,770 (+)NCBIT2T-CHM13v2.0
Casp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391956,382,640 - 56,430,780 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1956,385,561 - 56,430,776 (+)EnsemblGRCm39 Ensembl
GRCm381956,396,833 - 56,442,348 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1956,397,129 - 56,442,344 (+)EnsemblGRCm38mm10GRCm38
MGSCv371956,471,619 - 56,516,834 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361956,450,379 - 56,495,594 (+)NCBIMGSCv36mm8
Celera1958,584,433 - 58,629,610 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1951.84NCBI
Casp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81265,442,647 - 265,481,938 (+)NCBIGRCr8
mRatBN7.21255,437,438 - 255,476,737 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1255,437,172 - 255,476,729 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1263,654,318 - 263,686,579 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01270,360,357 - 270,392,618 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01263,006,435 - 263,038,671 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01277,190,557 - 277,242,779 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1277,190,964 - 277,242,774 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01284,572,208 - 284,623,736 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41262,689,300 - 262,721,591 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11262,900,344 - 262,932,633 (+)NCBI
Celera1251,144,026 - 251,176,065 (+)NCBICelera
Cytogenetic Map1q55NCBI
CASP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28125,557,882 - 125,609,366 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110125,563,218 - 125,614,702 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010110,273,318 - 110,324,800 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110113,707,188 - 113,758,630 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10113,707,780 - 113,758,626 (+)Ensemblpanpan1.1panPan2
CASP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12824,599,866 - 24,630,018 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2824,599,493 - 24,628,668 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2824,751,150 - 24,781,371 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02825,131,618 - 25,161,826 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2825,131,720 - 25,161,823 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12824,688,961 - 24,719,167 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02824,696,885 - 24,727,323 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02824,896,252 - 24,926,727 (+)NCBIUU_Cfam_GSD_1.0
Casp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721321,446,342 - 21,478,385 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364864,088,372 - 4,114,955 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364864,082,664 - 4,114,942 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASP7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14124,019,164 - 124,050,365 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114124,017,776 - 124,050,369 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CASP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19106,558,291 - 106,607,662 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9106,559,445 - 106,607,663 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604867,773,257 - 67,822,203 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Casp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473732,852,835 - 32,887,069 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473732,853,354 - 32,888,881 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000010083   ⟹   ENSCLAP00000009953
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495543118,686,190 - 18,723,524 (+)Ensembl
RefSeq Acc Id: XM_005387788   ⟹   XP_005387845
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543118,685,408 - 18,723,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005387789   ⟹   XP_005387846
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543118,686,186 - 18,723,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005387790   ⟹   XP_005387847
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543118,705,059 - 18,723,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005387791   ⟹   XP_005387848
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543118,705,277 - 18,723,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005387792   ⟹   XP_005387849
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543118,686,190 - 18,723,221 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013515832   ⟹   XP_013371286
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495543118,686,190 - 18,723,221 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005387845   ⟸   XM_005387788
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V7J5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005387849   ⟸   XM_005387792
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V7J5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005387846   ⟸   XM_005387789
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V7J5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005387847   ⟸   XM_005387790
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005387848   ⟸   XM_005387791
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013371286   ⟸   XM_013515832
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V7J5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000009953   ⟸   ENSCLAT00000010083

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000006895 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000010083 ENTREZGENE
  ENSCLAT00000010083.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1460 UniProtKB/TrEMBL
  Caspase-like UniProtKB/TrEMBL
InterPro Caspase-like_dom_sf UniProtKB/TrEMBL
  Caspase_cys_AS UniProtKB/TrEMBL
  Caspase_his_AS UniProtKB/TrEMBL
  Pept_C14_caspase UniProtKB/TrEMBL
  Pept_C14_p10 UniProtKB/TrEMBL
  Pept_C14_p20 UniProtKB/TrEMBL
  Pept_C14A UniProtKB/TrEMBL
NCBI Gene Casp7 ENTREZGENE
PANTHER PTHR10454 UniProtKB/TrEMBL
  PTHR10454:SF31 UniProtKB/TrEMBL
Pfam Peptidase_C14 UniProtKB/TrEMBL
PRINTS IL1BCENZYME UniProtKB/TrEMBL
PROSITE CASPASE_CYS UniProtKB/TrEMBL
  CASPASE_HIS UniProtKB/TrEMBL
  CASPASE_P10 UniProtKB/TrEMBL
  CASPASE_P20 UniProtKB/TrEMBL
SMART CASc UniProtKB/TrEMBL
Superfamily-SCOP SSF52129 UniProtKB/TrEMBL
UniProt A0A8C2V7J5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Casp7  caspase 7    caspase 7, apoptosis-related cysteine peptidase  Symbol and/or name change 5135510 APPROVED