Nfe2l2 (NFE2 like bZIP transcription factor 2)

Gene: Nfe2l2 (NFE2 like bZIP transcription factor 2) Chinchilla lanigera

Analyze

Symbol:

Nfe2l2

Name:

NFE2 like bZIP transcription factor 2 (Ensembl:nuclear factor, erythroid 2 like 2)

RGD ID:

8798257

Description:

ENCODES a protein that exhibits DNA binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN aflatoxin catabolic process (ortholog); cell redox homeostasis (ortholog); cellular response to angiotensin (ortholog); PARTICIPATES IN nuclear factor, erythroid 2 like 2 signaling pathway; oxidative stress response pathway; ASSOCIATED WITH Acidoses (ortholog); acute kidney failure (ortholog); Acute Lung Injury (ortholog); FOUND IN centrosome (ortholog); chromatin (ortholog); cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-related factor 2; nuclear factor, erythroid 2 like 2; nuclear factor, erythroid 2-like 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	19,532,103 - 19,535,944 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	19,510,122 - 19,536,428 (+)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Acidoses (ISO)

acute kidney failure (ISO)

Acute Lung Injury (ISO)

Alcoholic Liver Diseases (ISO)

allergic contact dermatitis (ISO)

Alzheimer's disease (ISO)

amyotrophic lateral sclerosis (ISO)

Animal Disease Models (ISO)

asthma (ISO)

Brain Injuries (ISO)

Breast Neoplasms (ISO)

Carcinogenesis (ISO)

Cardiac Fibrosis (ISO)

Cardiac Output, Low (ISO)

Cardiomegaly (ISO)

cataract (ISO)

Chemical and Drug Induced Liver Injury (ISO)

cholestasis (ISO)

Chromosome Breakage (ISO)

chronic kidney disease (ISO)

chronic obstructive pulmonary disease (ISO)

Chronic Tubulointerstitial Nephropathy (ISO)

colitis (ISO)

colorectal cancer (ISO)

congestive heart failure (ISO)

Diabetic Cardiomyopathies (ISO)

Diabetic Nephropathies (ISO)

diabetic retinopathy (ISO)

Disease Progression (ISO)

Emphysema (ISO)

Endometrial Neoplasms (ISO)

Endotoxemia (ISO)

esophagus squamous cell carcinoma (ISO)

Experimental Autoimmune Encephalomyelitis (ISO)

Experimental Colitis (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Liver Cirrhosis (ISO)

Experimental Mammary Neoplasms (ISO)

extrahepatic cholestasis (ISO)

Fetal Death (ISO)

Fetal Growth Retardation (ISO)

gastrointestinal system disease (ISO)

genetic disease (ISO)

genital herpes (ISO)

glucose intolerance (ISO)

head and neck squamous cell carcinoma (ISO)

Hepatic Insufficiency (ISO)

hepatocellular carcinoma (ISO)

Hepatomegaly (ISO)

Huntington's disease (ISO)

hyperglycemia (ISO)

Hyperplasia (ISO)

hypertension (ISO)

IMMUNODEFICIENCY, DEVELOPMENTAL DELAY, AND HYPOHOMOCYSTEINEMIA (ISO)

Insulin Resistance (ISO)

keratosis (ISO)

kidney disease (ISO)

Kidney Reperfusion Injury (ISO)

liver cirrhosis (ISO)

Liver Neoplasms (ISO)

Liver Reperfusion Injury (ISO)

lung adenocarcinoma (ISO)

lung cancer (ISO)

lung disease (ISO)

Lung Neoplasms (ISO)

lung non-small cell carcinoma (ISO)

lung squamous cell carcinoma (ISO)

macular degeneration (ISO)

metabolic dysfunction-associated steatohepatitis (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

Micronuclei, Chromosome-Defective (ISO)

middle cerebral artery infarction (ISO)

myocardial infarction (ISO)

Myocardial Reperfusion Injury (ISO)

Necrosis (ISO)

Neoplasm Invasiveness (ISO)

Neoplasm Metastasis (ISO)

Neoplastic Cell Transformation (ISO)

Neurodevelopmental Disorders (ISO)

obesity (ISO)

pancreatic ductal carcinoma (ISO)

pleurisy (ISO)

Premature Aging (ISO)

primary biliary cholangitis (ISO)

primary ovarian insufficiency (ISO)

Prostatic Neoplasms (ISO)

pulmonary emphysema (ISO)

pulmonary fibrosis (ISO)

renal cell carcinoma (ISO)

Renal Cell Carcinoma 1 (ISO)

sickle cell anemia (ISO)

Skin Neoplasms (ISO)

Spinal Cord Injuries (ISO)

Splenomegaly (ISO)

split hand-foot malformation 5 (ISO)

squamous cell carcinoma (ISO)

steatotic liver disease (ISO)

Subarachnoid Hemorrhage (ISO)

Sunburn (ISO)

toxic encephalopathy (ISO)

transitional cell carcinoma (ISO)

traumatic brain injury (ISO)

tuberculosis (ISO)

type 2 diabetes mellitus (ISO)

uterine cancer (ISO)

Uterine Cervical Neoplasms (ISO)

Vascular System Injuries (ISO)

Ventricular Dysfunction, Left (ISO)

Ventricular Remodeling (ISO)

visceral leishmaniasis (ISO)

visual epilepsy (ISO)

vitiligo (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aflatoxin catabolic process (ISO)

cell redox homeostasis (ISO)

cellular response to angiotensin (ISO)

cellular response to copper ion (ISO)

cellular response to fluid shear stress (ISO)

cellular response to glucose starvation (ISO)

cellular response to hydrogen peroxide (ISO)

cellular response to hypoxia (ISO)

cellular response to laminar fluid shear stress (ISO)

cellular response to methionine (ISO)

cellular response to oxidative stress (ISO)

cellular response to tumor necrosis factor (ISO)

cellular response to xenobiotic stimulus (ISO)

endoplasmic reticulum unfolded protein response (ISO)

inflammatory response (ISO)

negative regulation of cardiac muscle cell apoptotic process (ISO)

negative regulation of cellular process (ISO)

negative regulation of cellular response to hypoxia (ISO)

negative regulation of endothelial cell apoptotic process (ISO)

negative regulation of hematopoietic stem cell differentiation (ISO)

negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (ISO)

negative regulation of vascular associated smooth muscle cell migration (ISO)

PERK-mediated unfolded protein response (ISO)

positive regulation of angiogenesis (ISO)

positive regulation of blood coagulation (ISO)

positive regulation of blood vessel endothelial cell migration (ISO)

positive regulation of DNA-templated transcription (ISO)

positive regulation of gene expression (ISO)

positive regulation of glucose import (ISO)

positive regulation of glutathione biosynthetic process (ISO)

positive regulation of neuron projection development (ISO)

positive regulation of reactive oxygen species metabolic process (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

proteasomal ubiquitin-independent protein catabolic process (ISO)

proteasome-mediated ubiquitin-dependent protein catabolic process (ISO)

protein ubiquitination (ISO)

regulation of cellular response to oxidative stress (ISO)

regulation of DNA-templated transcription (ISO)

regulation of embryonic development (ISO)

regulation of innate immune response (ISO)

regulation of removal of superoxide radicals (ISO)

response to endoplasmic reticulum stress (ISO)

response to ischemia (ISO)

response to organic substance (ISO)

response to oxidative stress (ISO)

response to xenobiotic stimulus (ISO)

Cellular Component

centrosome (ISO)

chromatin (ISO)

cytoplasm (ISO)

cytosol (ISO)

Golgi apparatus (ISO)

mediator complex (ISO)

non-membrane-bounded organelle (ISO)

nucleoplasm (ISO)

nucleus (ISO)

plasma membrane (ISO)

protein-DNA complex (ISO)

RNA polymerase II transcription regulator complex (ISO)

Molecular Function

DNA binding (ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity (ISO)

molecular condensate scaffold activity (ISO)

protein binding (ISO)

protein domain specific binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (ISO)

RNA polymerase II-specific DNA-binding transcription factor binding (ISO)

sequence-specific DNA binding (ISO)

transcription cis-regulatory region binding (ISO)

transcription coregulator binding (ISO)

ubiquitin protein ligase binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

nuclear factor, erythroid 2 like 2 signaling pathway (ISO)

oxidative stress response pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Nfe2l2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	19,532,103 - 19,535,944 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	19,510,122 - 19,536,428 (+)	NCBI	ChiLan1.0	ChiLan1.0

NFE2L2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	177,230,303 - 177,264,727 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	177,218,667 - 177,392,756 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	178,095,031 - 178,129,455 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	177,803,282 - 177,837,663 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	177,920,542 - 177,954,924	NCBI
Celera	2	171,697,459 - 171,732,295 (-)	NCBI		Celera
Cytogenetic Map	2	q31.2	NCBI
HuRef	2	169,966,324 - 170,001,125 (-)	NCBI		HuRef
CHM1_1	2	178,100,863 - 178,135,685 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	177,712,539 - 177,746,971 (-)	NCBI		T2T-CHM13v2.0

Nfe2l2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	75,505,860 - 75,535,007 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	75,505,857 - 75,534,985 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	75,675,513 - 75,704,663 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	75,675,513 - 75,704,641 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	75,513,576 - 75,542,698 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	75,476,358 - 75,505,480 (-)	NCBI		MGSCv36	mm8
Celera	2	77,336,615 - 77,365,680 (-)	NCBI		Celera
Cytogenetic Map	2	C3	NCBI
cM Map	2	44.75	NCBI

Nfe2l2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	81,001,529 - 81,031,165 (-)	NCBI		GRCr8
mRatBN7.2	3	60,594,239 - 60,621,712 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	60,594,242 - 60,621,737 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	63,968,507 - 63,995,961 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	72,552,163 - 72,579,616 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	70,318,419 - 70,345,871 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	62,497,568 - 62,525,146 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	62,497,571 - 62,524,996 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	69,041,641 - 69,069,190 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	58,366,693 - 58,394,116 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	58,263,064 - 58,290,488 (-)	NCBI
Celera	3	60,095,041 - 60,122,464 (-)	NCBI		Celera
Cytogenetic Map	3	q23	NCBI

NFE2L2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	79,896,932 - 80,058,685 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	79,911,905 - 80,073,664 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	64,509,446 - 64,544,600 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	182,214,116 - 182,248,282 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	182,214,116 - 182,248,085 (-)	Ensembl	panpan1.1		panPan2

NFE2L2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	36	20,989,205 - 21,087,044 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	36	20,989,360 - 21,012,524 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	36	21,008,912 - 21,151,059 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	36	21,133,291 - 21,275,953 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	36	21,133,296 - 21,276,012 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	36	21,203,925 - 21,237,606 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	36	21,205,089 - 21,302,516 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	36	21,320,865 - 21,418,596 (-)	NCBI		UU_Cfam_GSD_1.0

Nfe2l2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	138,036,230 - 138,177,608 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936509	6,590,630 - 6,620,262 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936509	6,589,967 - 6,621,171 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NFE2L2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	82,973,656 - 83,146,183 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	82,967,485 - 83,146,185 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	92,433,294 - 92,469,024 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NFE2L2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	62,789,647 - 62,825,651 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	62,790,124 - 62,825,339 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	136,640,202 - 136,820,663 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nfe2l2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624787	14,355,791 - 14,381,251 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624787	14,355,330 - 14,381,353 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005373407	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013512710	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013512713	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01002133	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBBH01065128	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000019330 ⟹ ENSCLAP00000019145

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955403	19,532,103 - 19,535,944 (+)	Ensembl

RefSeq Acc Id:

XM_005373407 ⟹ XP_005373464

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955403	19,510,122 - 19,536,428 (+)	NCBI

Sequence:

show sequence

ATTTAGCGTTTCAGAATTGCAAGTTCAAAATGTATAAGGCAGGATATTCTGTTCTGTGCTGTCA
AGGGACATGGACTTGATTGACATACTCTGGAGGCAAGATATTGATCTTGGGGCAAGTCGAGAAG
TGTTTGACTTCACTCAGCGACAGAAGGAATATGAGCTGGAAAAACAGAAAAAACTTGAAAAGGA
AAGACAAGAACAACTCCAAAAGGAGCAAGAGAAAGCCTTTTTCGCTCAGTTACAACTAGATGAA
GAGACGGGTGAATTCCTCCCGATTCAGCCAGCCCAGCACATCCAGTCAGAAACCAGTGGATCTG
GCAACTACTCCCAGGTTGCCCACATTCCCAAACCAGATGCTTTGTACTTCGATGACTGCATGCA
GCTTTTGGCAGAGACATTCCCATTTGTAGATGACAATGAGGTTTCTTCACCCACATTTCAGTCC
CTTGTTCCCGATATTCCCAGCCACGTCGAAAGCCCAGTCTTCACTGCTCCCAACCAGGCTCAGT
CCCCTGAAGCTCCTGTGGAGATAGCCATGGGTGATGTGGAGGGCATGCAGCAGGACATGGAGGA
AATTTGGCAGGAGCTATTTTCCATTCCAGAATTACAGTGTCTTAATATTGAAAATGACAAGCTG
GTGGAGACTACCATGGTTCCAAGCCCGGAATCCAAACTGACAGAAATTGACAACAGTTACTTCT
ACTCATCAGTCCCTTCACTGGAAAAAGAAGTAGGGAGCTGCAGGCCAGAGTTTCTTAATACTTT
CGAGGACTCTTTCAGCAGCATCCTCTCCACAGAAGATCCCAACCAGCTGACAGTGAACTCATTA
AATTCAGATGGCACATTAAACACAGATTTTGGTGATGAATTTTATTCTGCTTTCATAGCAGAAC
CAAGCATCAGCAACAGCATGTCCTCCTCTGCCACTGTAAGCCAGTCACTCTCTGAACTTTTATA
TGGGCCCATTGATGTTTCTGATCTATCACTTTGTAAAGCTTTCAACAAAAATCACCCTGAAAGC
ACAGTAGAATTCAATGACTCTGACTCGGGCATTTCACTGAACACAAGTCCCAGCATAGCATCAC
CAGAACACTCTGTGGCTTCTTCCATCTATGGAGACCCACCAGCTGGCCTCAGTGATTCGGAAAT
GGAAGAGCTAGATAGTGCCCCTGGAAGTGTCAAACCCAGCGGTCCCAAAACACAGCCAGTATAT
TCTTCTGAGGATACTGCACAACCTCTGTCACCATCTCAAGGGCACAGTTCTTCCATGCATGATG
CCCAGTGTGAAAACACACCAAAGAAAGATCTGCCGGCAAGTCCTGGTCATCGAAAAACCCCATT
CACAAAAGACAAACATTCAAGCCGTTTGGAGGCTCATCTCACCAGAGATGAGCTTAGGGCAAAA
GCTCTCCATATCCCATTCCCTGTAGAAAAAATCATTAACCTCCCTGTTGACGACTTCCATGAAA
TGATGTCTAAGGAGCAATTCAGTGAAGCTCAAGTTGCACTAATTCGAGATATACGTAGGAGGGG
TAAGAATAAAGTAGCAGCTCAGAATTGCAGAAAAAGAAAACTGGAAAATATAGTAGAACTGGAG
CAAGATTTAGGTCACTTAAAAGATGAAAAAGAAAAATTACTCAAAGAAAAAGGAGAAAATGACA
AAAGCCTCCATCAACTGAAAAAACAACTCAGCACCTTGTATCTCGAAGTCTTCAGCATGCTACG
TGATGAAGATGGAAAGCCTTACTCTCCTAGTGAATACTCCTTGCAGCAAACAAAAGATGGCAAT
GTATTCCTGGTTCCCAAAAGTAAGCGGGCAGATGTTAAGAAAAACTAGACTGGGGAAGATTTGC
CTTTTCTGAGCTGTTTGTTTGTTTTGTACTGTTATCCTAAAAGAGCCTATTGTGATGTGAAACG
CAAGAAAATACTTTATAAGTAATTCTATGCAAAAATTATAGCCAAAACTATAGCATAGAAAATA
AGAAACATTAAAAAGCATTAAAATACTAGTATGTTGAATCAGTAGTTTCACTTTAACTATAAGG
TTAATTTGTTAGGGCACCATTTGGGCTTGTTTCTGTGTAAGTGTAAATACTACAGAATTTCTTA
TTTATACTGTTCTTGTCTCATTTGTTACATTCATAGATTTACATGATATGACATCTGCCTAAAC
GCAAATTGATGCAAAACTAACCACTATGTACTTTTTTAAATAAATACTGTACGAATAAAAAATG
GCATTTTTTATATTAAATTGCTTAGTTCTGGCAAAAAAATTTAAGAGCTGGTACTAATAAAGGA
ATATTATGACTTAAATTATA

hide sequence

RefSeq Acc Id:

XM_013512710 ⟹ XP_013368164

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955403	19,517,002 - 19,536,428 (+)	NCBI

Sequence:

show sequence

AGCTCATTTCCTGTGCTGTGGAGAGGCTTGCCTTTGGTGTTACATCTGGACACAGTCGTCCCTC
AGCATCCAAGCACATCGGTTCCTGATCCCCCTGCAGACAACAGAACCCACCGTGCTCAAGTCCT
TTGTACAAAGGGGCATGGACATGGACTTGATTGACATACTCTGGAGGCAAGATATTGATCTTGG
GGCAAGTCGAGAAGTGTTTGACTTCACTCAGCGACAGAAGGAATATGAGCTGGAAAAACAGAAA
AAACTTGAAAAGGAAAGACAAGAACAACTCCAAAAGGAGCAAGAGAAAGCCTTTTTCGCTCAGT
TACAACTAGATGAAGAGACGGGTGAATTCCTCCCGATTCAGCCAGCCCAGCACATCCAGTCAGA
AACCAGTGGATCTGGCAACTACTCCCAGGTTGCCCACATTCCCAAACCAGATGCTTTGTACTTC
GATGACTGCATGCAGCTTTTGGCAGAGACATTCCCATTTGTAGATGACAATGAGGTTTCTTCAC
CCACATTTCAGTCCCTTGTTCCCGATATTCCCAGCCACGTCGAAAGCCCAGTCTTCACTGCTCC
CAACCAGGCTCAGTCCCCTGAAGCTCCTGTGGAGATAGCCATGGGTGATGTGGAGGGCATGCAG
CAGGACATGGAGGAAATTTGGCAGGAGCTATTTTCCATTCCAGAATTACAGTGTCTTAATATTG
AAAATGACAAGCTGGTGGAGACTACCATGGTTCCAAGCCCGGAATCCAAACTGACAGAAATTGA
CAACAGTTACTTCTACTCATCAGTCCCTTCACTGGAAAAAGAAGTAGGGAGCTGCAGGCCAGAG
TTTCTTAATACTTTCGAGGACTCTTTCAGCAGCATCCTCTCCACAGAAGATCCCAACCAGCTGA
CAGTGAACTCATTAAATTCAGATGGCACATTAAACACAGATTTTGGTGATGAATTTTATTCTGC
TTTCATAGCAGAACCAAGCATCAGCAACAGCATGTCCTCCTCTGCCACTGTAAGCCAGTCACTC
TCTGAACTTTTATATGGGCCCATTGATGTTTCTGATCTATCACTTTGTAAAGCTTTCAACAAAA
ATCACCCTGAAAGCACAGTAGAATTCAATGACTCTGACTCGGGCATTTCACTGAACACAAGTCC
CAGCATAGCATCACCAGAACACTCTGTGGCTTCTTCCATCTATGGAGACCCACCAGCTGGCCTC
AGTGATTCGGAAATGGAAGAGCTAGATAGTGCCCCTGGAAGTGTCAAACCCAGCGGTCCCAAAA
CACAGCCAGTATATTCTTCTGAGGATACTGCACAACCTCTGTCACCATCTCAAGGGCACAGTTC
TTCCATGCATGATGCCCAGTGTGAAAACACACCAAAGAAAGATCTGCCGGCAAGTCCTGGTCAT
CGAAAAACCCCATTCACAAAAGACAAACATTCAAGCCGTTTGGAGGCTCATCTCACCAGAGATG
AGCTTAGGGCAAAAGCTCTCCATATCCCATTCCCTGTAGAAAAAATCATTAACCTCCCTGTTGA
CGACTTCCATGAAATGATGTCTAAGGAGCAATTCAGTGAAGCTCAAGTTGCACTAATTCGAGAT
ATACGTAGGAGGGGTAAGAATAAAGTAGCAGCTCAGAATTGCAGAAAAAGAAAACTGGAAAATA
TAGTAGAACTGGAGCAAGATTTAGGTCACTTAAAAGATGAAAAAGAAAAATTACTCAAAGAAAA
AGGAGAAAATGACAAAAGCCTCCATCAACTGAAAAAACAACTCAGCACCTTGTATCTCGAAGTC
TTCAGCATGCTACGTGATGAAGATGGAAAGCCTTACTCTCCTAGTGAATACTCCTTGCAGCAAA
CAAAAGATGGCAATGTATTCCTGGTTCCCAAAAGTAAGCGGGCAGATGTTAAGAAAAACTAGAC
TGGGGAAGATTTGCCTTTTCTGAGCTGTTTGTTTGTTTTGTACTGTTATCCTAAAAGAGCCTAT
TGTGATGTGAAACGCAAGAAAATACTTTATAAGTAATTCTATGCAAAAATTATAGCCAAAACTA
TAGCATAGAAAATAAGAAACATTAAAAAGCATTAAAATACTAGTATGTTGAATCAGTAGTTTCA
CTTTAACTATAAGGTTAATTTGTTAGGGCACCATTTGGGCTTGTTTCTGTGTAAGTGTAAATAC
TACAGAATTTCTTATTTATACTGTTCTTGTCTCATTTGTTACATTCATAGATTTACATGATATG
ACATCTGCCTAAACGCAAATTGATGCAAAACTAACCACTATGTACTTTTTTAAATAAATACTGT
ACGAATAAAAAATGGCATTTTTTATATTAAATTGCTTAGTTCTGGCAAAAAAATTTAAGAGCTG
GTACTAATAAAGGAATATTATGACTTAAATTATA

hide sequence

RefSeq Acc Id:

XM_013512713 ⟹ XP_013368167

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955403	19,517,000 - 19,536,428 (+)	NCBI

Sequence:

show sequence

CCAGCTCATTTCCTGTGCTGTGGAGAGGCTTGCCTTTGGTGTTACATCTGGACACAGTCGTCCC
TCAGCATCCAAGCACATCGGTTCCTGATCCCCCTGCAGACAACAGAACCCACCGTGCTCAAGTC
CTTTGTACAAAGGGGCATGGACATGGACTTGATTGACATACTCTGGAGGCAAGATATTGATCTT
GGGGCAAGTCGAGAAGTGTTTGACTTCACTCAGCGACAGAAGGAATATGAGCTGGAAAAACAGA
AAAAACTTGAAAAGGAAAGACAAGAACAACTCCAAAAGGAGCAAGAGAAAGCCTTTTTCGCTCA
GTTACAACTAGATGAAGAGACGGGTGAATTCCTCCCGATTCAGCCAGCCCAGCACATCCAGTCA
GAAACCAGTGGATCTGGCAACTACTCCCAGGTTTCTTCACCCACATTTCAGTCCCTTGTTCCCG
ATATTCCCAGCCACGTCGAAAGCCCAGTCTTCACTGCTCCCAACCAGGCTCAGTCCCCTGAAGC
TCCTGTGGAGATAGCCATGGGTGATGTGGAGGGCATGCAGCAGGACATGGAGGAAATTTGGCAG
GAGCTATTTTCCATTCCAGAATTACAGTGTCTTAATATTGAAAATGACAAGCTGGTGGAGACTA
CCATGGTTCCAAGCCCGGAATCCAAACTGACAGAAATTGACAACAGTTACTTCTACTCATCAGT
CCCTTCACTGGAAAAAGAAGTAGGGAGCTGCAGGCCAGAGTTTCTTAATACTTTCGAGGACTCT
TTCAGCAGCATCCTCTCCACAGAAGATCCCAACCAGCTGACAGTGAACTCATTAAATTCAGATG
GCACATTAAACACAGATTTTGGTGATGAATTTTATTCTGCTTTCATAGCAGAACCAAGCATCAG
CAACAGCATGTCCTCCTCTGCCACTGTAAGCCAGTCACTCTCTGAACTTTTATATGGGCCCATT
GATGTTTCTGATCTATCACTTTGTAAAGCTTTCAACAAAAATCACCCTGAAAGCACAGTAGAAT
TCAATGACTCTGACTCGGGCATTTCACTGAACACAAGTCCCAGCATAGCATCACCAGAACACTC
TGTGGCTTCTTCCATCTATGGAGACCCACCAGCTGGCCTCAGTGATTCGGAAATGGAAGAGCTA
GATAGTGCCCCTGGAAGTGTCAAACCCAGCGGTCCCAAAACACAGCCAGTATATTCTTCTGAGG
ATACTGCACAACCTCTGTCACCATCTCAAGGGCACAGTTCTTCCATGCATGATGCCCAGTGTGA
AAACACACCAAAGAAAGATCTGCCGGCAAGTCCTGGTCATCGAAAAACCCCATTCACAAAAGAC
AAACATTCAAGCCGTTTGGAGGCTCATCTCACCAGAGATGAGCTTAGGGCAAAAGCTCTCCATA
TCCCATTCCCTGTAGAAAAAATCATTAACCTCCCTGTTGACGACTTCCATGAAATGATGTCTAA
GGAGCAATTCAGTGAAGCTCAAGTTGCACTAATTCGAGATATACGTAGGAGGGGTAAGAATAAA
GTAGCAGCTCAGAATTGCAGAAAAAGAAAACTGGAAAATATAGTAGAACTGGAGCAAGATTTAG
GTCACTTAAAAGATGAAAAAGAAAAATTACTCAAAGAAAAAGGAGAAAATGACAAAAGCCTCCA
TCAACTGAAAAAACAACTCAGCACCTTGTATCTCGAAGTCTTCAGCATGCTACGTGATGAAGAT
GGAAAGCCTTACTCTCCTAGTGAATACTCCTTGCAGCAAACAAAAGATGGCAATGTATTCCTGG
TTCCCAAAAGTAAGCGGGCAGATGTTAAGAAAAACTAGACTGGGGAAGATTTGCCTTTTCTGAG
CTGTTTGTTTGTTTTGTACTGTTATCCTAAAAGAGCCTATTGTGATGTGAAACGCAAGAAAATA
CTTTATAAGTAATTCTATGCAAAAATTATAGCCAAAACTATAGCATAGAAAATAAGAAACATTA
AAAAGCATTAAAATACTAGTATGTTGAATCAGTAGTTTCACTTTAACTATAAGGTTAATTTGTT
AGGGCACCATTTGGGCTTGTTTCTGTGTAAGTGTAAATACTACAGAATTTCTTATTTATACTGT
TCTTGTCTCATTTGTTACATTCATAGATTTACATGATATGACATCTGCCTAAACGCAAATTGAT
GCAAAACTAACCACTATGTACTTTTTTAAATAAATACTGTACGAATAAAAAATGGCATTTTTTA
TATTAAATTGCTTAGTTCTGGCAAAAAAATTTAAGAGCTGGTACTAATAAAGGAATATTATGAC
TTAAATTATA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005373464	(Get FASTA)	NCBI Sequence Viewer
	XP_013368164	(Get FASTA)	NCBI Sequence Viewer
	XP_013368167	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000019145
	ENSCLAP00000019145.1

RefSeq Acc Id:	XP_005373464 ⟸ XM_005373407
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C2YS28 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDLIDILWRQDIDLGASREVFDFTQRQKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQLDEET GEFLPIQPAQHIQSETSGSGNYSQVAHIPKPDALYFDDCMQLLAETFPFVDDNEVSSPTFQSLV PDIPSHVESPVFTAPNQAQSPEAPVEIAMGDVEGMQQDMEEIWQELFSIPELQCLNIENDKLVE TTMVPSPESKLTEIDNSYFYSSVPSLEKEVGSCRPEFLNTFEDSFSSILSTEDPNQLTVNSLNS DGTLNTDFGDEFYSAFIAEPSISNSMSSSATVSQSLSELLYGPIDVSDLSLCKAFNKNHPESTV EFNDSDSGISLNTSPSIASPEHSVASSIYGDPPAGLSDSEMEELDSAPGSVKPSGPKTQPVYSS EDTAQPLSPSQGHSSSMHDAQCENTPKKDLPASPGHRKTPFTKDKHSSRLEAHLTRDELRAKAL HIPFPVEKIINLPVDDFHEMMSKEQFSEAQVALIRDIRRRGKNKVAAQNCRKRKLENIVELEQD LGHLKDEKEKLLKEKGENDKSLHQLKKQLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTKDGNVF LVPKSKRADVKKN hide sequence

RefSeq Acc Id:

XP_013368167 ⟸ XM_013512713

- Peptide Label:

isoform X2

- Sequence:

show sequence

MDMDLIDILWRQDIDLGASREVFDFTQRQKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQLDE
ETGEFLPIQPAQHIQSETSGSGNYSQVSSPTFQSLVPDIPSHVESPVFTAPNQAQSPEAPVEIA
MGDVEGMQQDMEEIWQELFSIPELQCLNIENDKLVETTMVPSPESKLTEIDNSYFYSSVPSLEK
EVGSCRPEFLNTFEDSFSSILSTEDPNQLTVNSLNSDGTLNTDFGDEFYSAFIAEPSISNSMSS
SATVSQSLSELLYGPIDVSDLSLCKAFNKNHPESTVEFNDSDSGISLNTSPSIASPEHSVASSI
YGDPPAGLSDSEMEELDSAPGSVKPSGPKTQPVYSSEDTAQPLSPSQGHSSSMHDAQCENTPKK
DLPASPGHRKTPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVDDFHEMMSKEQFSE
AQVALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLGHLKDEKEKLLKEKGENDKSLHQLKKQ
LSTLYLEVFSMLRDEDGKPYSPSEYSLQQTKDGNVFLVPKSKRADVKKN

hide sequence

RefSeq Acc Id:

XP_013368164 ⟸ XM_013512710

- Peptide Label:

isoform X1

- Sequence:

show sequence

MDMDLIDILWRQDIDLGASREVFDFTQRQKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQLDE
ETGEFLPIQPAQHIQSETSGSGNYSQVAHIPKPDALYFDDCMQLLAETFPFVDDNEVSSPTFQS
LVPDIPSHVESPVFTAPNQAQSPEAPVEIAMGDVEGMQQDMEEIWQELFSIPELQCLNIENDKL
VETTMVPSPESKLTEIDNSYFYSSVPSLEKEVGSCRPEFLNTFEDSFSSILSTEDPNQLTVNSL
NSDGTLNTDFGDEFYSAFIAEPSISNSMSSSATVSQSLSELLYGPIDVSDLSLCKAFNKNHPES
TVEFNDSDSGISLNTSPSIASPEHSVASSIYGDPPAGLSDSEMEELDSAPGSVKPSGPKTQPVY
SSEDTAQPLSPSQGHSSSMHDAQCENTPKKDLPASPGHRKTPFTKDKHSSRLEAHLTRDELRAK
ALHIPFPVEKIINLPVDDFHEMMSKEQFSEAQVALIRDIRRRGKNKVAAQNCRKRKLENIVELE
QDLGHLKDEKEKLLKEKGENDKSLHQLKKQLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTKDGN
VFLVPKSKRADVKKN

hide sequence

RefSeq Acc Id:

ENSCLAP00000019145 ⟸ ENSCLAT00000019330

Protein Domains

bZIP

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000013122	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000019330	ENTREZGENE
	ENSCLAT00000019330.1	UniProtKB/TrEMBL
Gene3D-CATH	Transcription factor, Skn-1-like, DNA-binding domain	UniProtKB/TrEMBL
InterPro	bZIP	UniProtKB/TrEMBL
	bZIP_Maf	UniProtKB/TrEMBL
	bZIP_sf	UniProtKB/TrEMBL
	NFE2-like	UniProtKB/TrEMBL
	TF_DNA-bd_sf	UniProtKB/TrEMBL
NCBI Gene	Nfe2l2	ENTREZGENE
PANTHER	NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR	UniProtKB/TrEMBL
	PTHR24411:SF3	UniProtKB/TrEMBL
Pfam	bZIP_Maf	UniProtKB/TrEMBL
PROSITE	BZIP	UniProtKB/TrEMBL
	BZIP_BASIC	UniProtKB/TrEMBL
SMART	BRLZ	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47454	UniProtKB/TrEMBL
	SSF57959	UniProtKB/TrEMBL
UniProt	A0A8C2YS28	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-10-05	Nfe2l2	NFE2 like bZIP transcription factor 2	Nfe2l2	nuclear factor, erythroid 2 like 2	Symbol and/or name change	5135510	APPROVED
2016-08-16	Nfe2l2	nuclear factor, erythroid 2 like 2		nuclear factor, erythroid 2-like 2	Symbol and/or name change	5135510	APPROVED
2015-08-25	Nfe2l2	nuclear factor, erythroid 2-like 2		nuclear factor (erythroid-derived 2)-like 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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