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ONTOLOGY REPORT - ANNOTATIONS

Term:transcription initiation at RNA polymerase II promoter
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Accession:GO:0006367 term browser browse the term
Definition:A transcription initiation process that takes place at a RNA polymerase II gene promoter. Messenger RNAs (mRNA) genes, as well as some non-coding RNAs, are transcribed by RNA polymerase II.
Comment:Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.
Synonyms:exact_synonym: transcription initiation from Pol II promoter;   transcription initiation from RNA polymerase II promoter

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transcription initiation at RNA polymerase II promoter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnh cyclin H involved_in ISO (PMID:7533895), (PMID:8692841) ARUK-UCL PMID:7533895 PMID:8692841 NCBI chrNW_004955418:23,790,398...23,807,509
Ensembl chrNW_004955418:23,790,001...23,807,702 		JBrowse link
G Cdk7 cyclin dependent kinase 7 involved_in ISO (PMID:7533895), (PMID:8692841) ARUK-UCL PMID:7533895 PMID:8692841 NCBI chrNW_004955446:54,401...87,884
Ensembl chrNW_004955446:54,448...90,191 		JBrowse link
G Eloa elongin A involved_in ISO (PMID:7660122) UniProt PMID:7660122 NCBI chrNW_004955452:3,668,868...3,681,506
Ensembl chrNW_004955452:3,668,864...3,681,481 		JBrowse link
G Elob elongin B involved_in ISO (PMID:7660122) UniProt PMID:7660122 NCBI chrNW_004955442:14,498,666...14,501,895
Ensembl chrNW_004955442:14,498,725...14,502,135 		JBrowse link
G Eloc elongin C involved_in ISO (PMID:7660122) UniProt PMID:7660122 NCBI chrNW_004955444:6,400,721...6,415,881
Ensembl chrNW_004955444:6,400,832...6,415,881 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit involved_in ISO (PMID:8692841) UniProt PMID:8692841 NCBI chrNW_004955555:2,355,005...2,369,599
Ensembl chrNW_004955555:2,355,005...2,369,599 		JBrowse link
G Ercc3 ERCC excision repair 3, TFIIH core complex helicase subunit involved_in ISO (PMID:8692841) UniProt PMID:8692841 NCBI chrNW_004955459:3,210,936...3,238,401
Ensembl chrNW_004955459:3,210,479...3,242,576 		JBrowse link
G Gtf2a2 general transcription factor IIA subunit 2 involved_in ISO (PMID:7958899) BHF-UCL PMID:7958899 NCBI chrNW_004955450:15,181,824...15,195,594 JBrowse link
G Gtf2b general transcription factor IIB involved_in ISO (PMID:12931194), (PMID:9420329)
(PMID:3029109)		 GO_Central
UniProt		 PMID:3029109 PMID:9420329 PMID:12931194 NCBI chrNW_004955423:5,420,795...5,447,148
Ensembl chrNW_004955423:5,420,584...5,447,148 		JBrowse link
G Gtf2f1 general transcription factor IIF subunit 1 involved_in ISO (PMID:15351637), (PMID:7929273) ARUK-UCL PMID:7929273 PMID:15351637 NCBI chrNW_004955495:3,208,334...3,217,460
Ensembl chrNW_004955495:3,208,733...3,217,163 		JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 involved_in ISO PMID:7929273
(PMID:15351637)		 ARUK-UCL
ComplexPortal		 PMID:7929273 PMID:15351637 RGD:9681417 NCBI chrNW_004955518:2,912,259...3,064,298
Ensembl chrNW_004955518:2,912,259...3,064,298 		JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 involved_in ISO (PMID:8692841) UniProt PMID:8692841 NCBI chrNW_004955414:33,028,701...33,063,233
Ensembl chrNW_004955414:33,028,701...33,063,233 		JBrowse link
G Maz MYC associated zinc finger protein involved_in ISO (PMID:1502157) UniProt PMID:1502157 NCBI chrNW_004955493:7,149,600...7,152,449 JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase involved_in ISO (PMID:8692841) UniProt PMID:8692841 NCBI chrNW_004955466:8,690,960...8,895,021
Ensembl chrNW_004955466:8,690,960...8,895,021 		JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:25412659)
(PMID:17996705)		 ParkinsonsUK-UCL
BHF-UCL		 PMID:17996705 PMID:25412659 NCBI chrNW_004955475:10,930,175...11,006,876
Ensembl chrNW_004955475:10,930,192...11,005,724 		JBrowse link
G Taf10 TATA-box binding protein associated factor 10 involved_in ISO (PMID:9603525) UniProt PMID:9603525 NCBI chrNW_004955414:22,322,954...22,324,412
Ensembl chrNW_004955414:22,323,031...22,324,367 		JBrowse link
G Taf2 TATA-box binding protein associated factor 2 involved_in ISO (PMID:9418870)
(PMID:10409744)		 UniProt PMID:9418870 PMID:10409744 NCBI chrNW_004955417:25,457,615...25,515,923 JBrowse link
G Taf4 TATA-box binding protein associated factor 4 involved_in ISO (PMID:12771217), (PMID:9603525) UniProt PMID:9603525 PMID:12771217 NCBI chrNW_004955528:1,951,952...2,020,592
Ensembl chrNW_004955528:1,994,249...2,020,494 		JBrowse link
G Taf5 TATA-box binding protein associated factor 5 involved_in ISO (PMID:9045704), (PMID:9603525) UniProt PMID:9045704 PMID:9603525 NCBI chrNW_004955485:7,159,199...7,176,269
Ensembl chrNW_004955485:7,160,022...7,175,608 		JBrowse link
G Taf6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:15328371), (PMID:9603525) UniProt PMID:9603525 PMID:15328371 NCBI chrNW_004955573:752,646...759,292
Ensembl chrNW_004955573:752,601...759,292 		JBrowse link
G Taf7 TATA-box binding protein associated factor 7 involved_in ISO (PMID:16407123), (PMID:9603525) UniProt PMID:9603525 PMID:16407123 NCBI chrNW_004955415:12,453,655...12,456,070
Ensembl chrNW_004955415:12,453,655...12,456,070 		JBrowse link
negative regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:8006019) UniProt PMID:8006019 NCBI chrNW_004955431:15,373,207...15,377,339
Ensembl chrNW_004955431:15,373,207...15,377,339 		JBrowse link
G Thra thyroid hormone receptor alpha involved_in ISO (PMID:8524305) UniProt PMID:8524305 NCBI chrNW_004955451:14,731,746...14,743,545
Ensembl chrNW_004955451:14,731,746...14,744,367 		JBrowse link
negative regulation of transcription initiation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 involved_in ISO (PMID:10692439) BHF-UCL PMID:10692439 NCBI chrNW_004955436:7,060,930...7,070,610
Ensembl chrNW_004955436:7,060,930...7,070,030 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:29203640) UniProt PMID:29203640 NCBI chrNW_004955461:2,714,022...2,718,872
Ensembl chrNW_004955461:2,714,022...2,718,982 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (MGI:6106288|PMID:29138493) UniProt PMID:29138493 MGI:6106288 NCBI chrNW_004955404:618,092...639,424
Ensembl chrNW_004955404:618,092...639,704 		JBrowse link
G Znf451 zinc finger protein 451 involved_in ISO (PMID:24324267) UniProt PMID:24324267 NCBI chrNW_004955502:3,003,822...3,087,529
Ensembl chrNW_004955502:2,999,976...3,048,464 		JBrowse link
G Znf473 zinc finger protein 473 ISO RGD PMID:12748187 RGD:1299608 NCBI chrNW_004955559:911,785...932,510
Ensembl chrNW_004955559:908,036...918,979 		JBrowse link
positive regulation of gene expression via chromosomal CpG island demethylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 involved_in ISO (PMID:21496894) UniProt PMID:21496894 NCBI chrNW_004955550:1,273,170...1,275,843
Ensembl chrNW_004955550:1,273,284...1,279,743 		JBrowse link
G Apobec1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 involved_in ISO (MGI:5285126|PMID:21496894) UniProt PMID:21496894 MGI:5285126 NCBI chrNW_004955413:6,471,933...6,480,475
Ensembl chrNW_004955413:6,471,953...6,480,469 		JBrowse link
G Apobec2 apolipoprotein B mRNA editing enzyme catalytic subunit 2 involved_in ISO (PMID:21496894) UniProt PMID:21496894 NCBI chrNW_004955437:7,725,092...7,735,892
Ensembl chrNW_004955437:7,724,988...7,735,893 		JBrowse link
G Egr1 early growth response 1 involved_in ISO (MGI:6362262|PMID:31467272) ARUK-UCL PMID:31467272 MGI:6362262 NCBI chrNW_004955418:2,001,509...2,005,269
Ensembl chrNW_004955418:2,002,699...2,005,007 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase involved_in ISO (PMID:27251462) ARUK-UCL PMID:27251462 NCBI chrNW_004955561:1,277,362...1,282,949
Ensembl chrNW_004955561:1,277,365...1,282,793 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 involved_in ISO (PMID:21496894)
(MGI:3844762|PMID:19372391), (MGI:5285126|PMID:21496894)
(MGI:6362262|PMID:31467272)		 UniProt
ARUK-UCL		 PMID:19372391 PMID:21496894 PMID:31467272 MGI:3844762 MGI:5285126 MGI:6362262 NCBI chrNW_004955425:20,767,406...20,857,165 JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 involved_in ISO (PMID:24315485) ARUK-UCL PMID:24315485 NCBI chrNW_004955496:3,885,684...3,963,056
Ensembl chrNW_004955496:3,885,035...3,926,106 		JBrowse link
G Zmpste24 zinc metallopeptidase STE24 acts_upstream_of_or_within ISO (PMID:20961378) MGI PMID:20961378 NCBI chrNW_004955537:82,724...134,609
Ensembl chrNW_004955537:81,920...134,609 		JBrowse link
positive regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor acts_upstream_of_or_within ISO (PMID:8215422) MGI PMID:8215422 NCBI chrNW_004955410:20,428,531...20,459,482
Ensembl chrNW_004955410:20,428,546...20,456,836 		JBrowse link
G Cand1 cullin associated and neddylation dissociated 1 involved_in ISO PMID:10567521 UniProt PMID:10567521 RGD:8553447 NCBI chrNW_004955458:13,815,819...13,850,007
Ensembl chrNW_004955458:13,815,819...13,850,007 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO RGD PMID:16891311 RGD:1625706 NCBI chrNW_004955457:7,424,403...7,490,630
Ensembl chrNW_004955457:7,431,736...7,491,149 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO (PMID:21245044) MGI PMID:21245044 NCBI chrNW_004955456:3,617,988...3,721,791
Ensembl chrNW_004955456:3,635,380...3,721,791 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:24289924) BHF-UCL PMID:24289924 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (PMID:19056892) MGI PMID:19056892 NCBI chrNW_004955500:7,782,782...7,800,281
Ensembl chrNW_004955500:7,782,782...7,788,309 		JBrowse link
positive regulation of transcription initiation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:21993297) UniProt PMID:21993297 NCBI chrNW_004955448:5,634,072...5,676,272
Ensembl chrNW_004955448:5,634,072...5,676,319 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO (PMID:22323595) MGI PMID:22323595 NCBI chrNW_004955555:2,393,510...2,430,180
Ensembl chrNW_004955555:2,393,278...2,406,582 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO (PMID:22323595) MGI PMID:22323595 NCBI chrNW_004955556:745,175...812,215
Ensembl chrNW_004955556:748,231...813,133 		JBrowse link
G Gtf2a1 general transcription factor IIA subunit 1 involved_in ISO (PMID:11030333) ComplexPortal PMID:11030333 NCBI chrNW_004955438:4,787,190...4,825,578
Ensembl chrNW_004955438:4,787,190...4,825,577 		JBrowse link
G Gtf2a2 general transcription factor IIA subunit 2 involved_in ISO (PMID:11030333) ComplexPortal PMID:11030333 NCBI chrNW_004955450:15,181,824...15,195,594 JBrowse link
G Hnf1a HNF1 homeobox A involved_in ISO (PMID:15355349) UniProt PMID:15355349 NCBI chrNW_004955455:10,694,102...10,717,613
Ensembl chrNW_004955455:10,694,102...10,717,613 		JBrowse link
G Hnf1b HNF1 homeobox B involved_in ISO (PMID:15355349) UniProt PMID:15355349 NCBI chrNW_004955451:320,283...371,420
Ensembl chrNW_004955451:320,283...371,420 		JBrowse link
G Med1 mediator complex subunit 1 involved_in ISO (PMID:12218053), (PMID:16314496) UniProt PMID:12218053 PMID:16314496 NCBI chrNW_004955451:14,204,326...14,237,809
Ensembl chrNW_004955451:14,202,744...14,237,797 		JBrowse link
G Med12 mediator complex subunit 12 involved_in ISO (PMID:12218053) UniProt PMID:12218053 NCBI chrNW_004955475:10,687,168...10,710,286
Ensembl chrNW_004955475:10,687,367...10,710,053 		JBrowse link
G Med13 mediator complex subunit 13 involved_in ISO (PMID:12218053) UniProt PMID:12218053 NCBI chrNW_004955451:2,891,583...3,008,230
Ensembl chrNW_004955451:2,895,419...3,008,230 		JBrowse link
G Med14 mediator complex subunit 14 involved_in ISO (PMID:12218053) UniProt PMID:12218053 NCBI chrNW_004955565:1,888,442...1,959,141
Ensembl chrNW_004955565:1,888,443...1,959,141 		JBrowse link
G Med16 mediator complex subunit 16 involved_in ISO (PMID:12218053) UniProt PMID:12218053 NCBI chrNW_004955495:6,939,084...6,955,885
Ensembl chrNW_004955495:6,934,078...6,959,190 		JBrowse link
G Med17 mediator complex subunit 17 involved_in ISO (PMID:12218053) UniProt PMID:12218053 NCBI chrNW_004955414:755,975...779,934
Ensembl chrNW_004955414:755,975...777,480 		JBrowse link
G Med24 mediator complex subunit 24 involved_in ISO (PMID:12218053) UniProt PMID:12218053 NCBI chrNW_004955451:14,690,721...14,712,038
Ensembl chrNW_004955451:14,690,952...14,711,965 		JBrowse link
G Med30 mediator complex subunit 30 involved_in ISO (PMID:12218053) UniProt PMID:12218053 NCBI chrNW_004955417:23,538,984...23,557,837
Ensembl chrNW_004955417:23,538,809...23,559,611 		JBrowse link
G Med4 mediator complex subunit 4 involved_in ISO (PMID:12218053) UniProt PMID:12218053 NCBI chrNW_004955431:1,794,863...1,812,641
Ensembl chrNW_004955431:1,794,115...1,812,889 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (MGI:6377809|PMID:26691508) CACAO PMID:26691508 MGI:6377809 NCBI chrNW_004955461:2,714,022...2,718,872
Ensembl chrNW_004955461:2,714,022...2,718,982 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:16322095) MGI PMID:16322095 NCBI chrNW_004955496:5,842,734...5,950,995
Ensembl chrNW_004955496:5,842,600...5,927,885 		JBrowse link
G Nfkbia NFKB inhibitor alpha involved_in ISO (PMID:16322095) MGI PMID:16322095 NCBI chrNW_004955409:25,691,673...25,695,151
Ensembl chrNW_004955409:25,691,534...25,697,520 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in ISO (MGI:83559|PMID:8887666) BHF-UCL PMID:8887666 MGI:83559 NCBI chrNW_004955408:25,833,649...25,836,673
Ensembl chrNW_004955408:25,832,683...25,836,840 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:17925232)
(MGI:4354659|PMID:19583951), (MGI:4821506|PMID:20671152)		 UniProt PMID:17925232 PMID:19583951 PMID:20671152 MGI:4354659 MGI:4821506 NCBI chrNW_004955491:8,177,422...8,219,764
Ensembl chrNW_004955491:8,177,422...8,219,766 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (MGI:6377809|PMID:26691508) CACAO PMID:26691508 MGI:6377809 NCBI chrNW_004955583:995,707...1,003,202 JBrowse link
G Srf serum response factor involved_in ISO (PMID:8887666) BHF-UCL PMID:8887666 NCBI chrNW_004955437:9,100,546...9,109,305
Ensembl chrNW_004955437:9,098,968...9,107,057 		JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955475:10,930,175...11,006,876
Ensembl chrNW_004955475:10,930,192...11,005,724 		JBrowse link
G Taf10 TATA-box binding protein associated factor 10 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955414:22,322,954...22,324,412
Ensembl chrNW_004955414:22,323,031...22,324,367 		JBrowse link
G Taf11 TATA-box binding protein associated factor 11 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955437:2,908,939...2,916,154
Ensembl chrNW_004955437:2,908,939...2,916,154 		JBrowse link
G Taf13 TATA-box binding protein associated factor 13 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955435:12,488,578...12,496,894
Ensembl chrNW_004955435:12,486,126...12,496,894 		JBrowse link
G Taf2 TATA-box binding protein associated factor 2 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955417:25,457,615...25,515,923 JBrowse link
G Taf3 TATA-box binding protein associated factor 3 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955421:24,263,395...24,414,472 JBrowse link
G Taf4 TATA-box binding protein associated factor 4 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955528:1,951,952...2,020,592
Ensembl chrNW_004955528:1,994,249...2,020,494 		JBrowse link
G Taf4b TATA-box binding protein associated factor 4b involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955402:14,296,202...14,425,298
Ensembl chrNW_004955402:14,296,202...14,425,321 		JBrowse link
G Taf5 TATA-box binding protein associated factor 5 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955485:7,159,199...7,176,269
Ensembl chrNW_004955485:7,160,022...7,175,608 		JBrowse link
G Taf6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:11583621), (PMID:17884155), (PMID:18628956) UniProt PMID:11583621 PMID:17884155 PMID:18628956 NCBI chrNW_004955573:752,646...759,292
Ensembl chrNW_004955573:752,601...759,292 		JBrowse link
G Taf7 TATA-box binding protein associated factor 7 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955415:12,453,655...12,456,070
Ensembl chrNW_004955415:12,453,655...12,456,070 		JBrowse link
G Taf8 TATA-box binding protein associated factor 8 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955437:8,317,437...8,328,544
Ensembl chrNW_004955437:8,317,437...8,328,804 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955575:74,506...76,272
Ensembl chrNW_004955575:74,506...76,272 		JBrowse link
G Tbp TATA-box binding protein involved_in ISO (PMID:17884155) ComplexPortal PMID:17884155 NCBI chrNW_004955411:3,268,147...3,285,567
Ensembl chrNW_004955411:3,268,147...3,285,077 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor acts_upstream_of_or_within ISO (PMID:22323595) MGI PMID:22323595 NCBI chrNW_004955419:27,751,042...27,774,917
Ensembl chrNW_004955419:27,751,043...27,774,917 		JBrowse link
G Znhit1 zinc finger HIT-type containing 1 involved_in ISO (MGI:6106288|PMID:29138493) UniProt PMID:29138493 MGI:6106288 NCBI chrNW_004955456:16,070,622...16,082,286
Ensembl chrNW_004955456:16,070,622...16,082,286 		JBrowse link
regulation of transcription initiation by RNA polymerase II term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxo1 forkhead box O1 involved_in ISO PMID:19483080 UniProt PMID:19483080 RGD:401901209 NCBI chrNW_004955431:5,797,359...5,890,758 JBrowse link
regulation of transcriptional start site selection at RNA polymerase II promoter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pwwp2a PWWP domain containing 2A involved_in ISO (MGI:6867108|PMID:33235983) UniProt PMID:33235983 MGI:6867108 NCBI chrNW_004955408:14,007,982...14,051,149
Ensembl chrNW_004955408:14,025,964...14,051,149 		JBrowse link
RNA polymerase II preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 involved_in ISO (PMID:9841876) GO_Central PMID:9841876 NCBI chrNW_004955439:9,588,631...9,953,606
Ensembl chrNW_004955439:9,588,201...9,963,353 		JBrowse link
G Gtf2a2 general transcription factor IIA subunit 2 involved_in ISO (PMID:7958899), (PMID:8626665) BHF-UCL PMID:7958899 PMID:8626665 NCBI chrNW_004955450:15,181,824...15,195,594 JBrowse link
G Gtf2b general transcription factor IIB involved_in ISO (PMID:3029109), (PMID:9841876)
(PMID:8413225)		 CAFA
UniProt		 PMID:3029109 PMID:8413225 PMID:9841876 NCBI chrNW_004955423:5,420,795...5,447,148
Ensembl chrNW_004955423:5,420,584...5,447,148 		JBrowse link
G Gtf2f2 general transcription factor IIF subunit 2 ISO RGD PMID:7929273 RGD:9681417 NCBI chrNW_004955518:2,912,259...3,064,298
Ensembl chrNW_004955518:2,912,259...3,064,298 		JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:27007846) ComplexPortal PMID:27007846 NCBI chrNW_004955475:10,930,175...11,006,876
Ensembl chrNW_004955475:10,930,192...11,005,724 		JBrowse link
G Taf10 TATA-box binding protein associated factor 10 involved_in ISO (PMID:27007846)
(PMID:28893950)		 ComplexPortal
MGI		 PMID:27007846 PMID:28893950 NCBI chrNW_004955414:22,322,954...22,324,412
Ensembl chrNW_004955414:22,323,031...22,324,367 		JBrowse link
G Taf11 TATA-box binding protein associated factor 11 involved_in ISO (PMID:27007846) ComplexPortal PMID:27007846 NCBI chrNW_004955437:2,908,939...2,916,154
Ensembl chrNW_004955437:2,908,939...2,916,154 		JBrowse link
G Taf13 TATA-box binding protein associated factor 13 involved_in ISO (PMID:27007846) ComplexPortal PMID:27007846 NCBI chrNW_004955435:12,488,578...12,496,894
Ensembl chrNW_004955435:12,486,126...12,496,894 		JBrowse link
G Taf2 TATA-box binding protein associated factor 2 involved_in ISO (PMID:27007846) ComplexPortal PMID:27007846 NCBI chrNW_004955417:25,457,615...25,515,923 JBrowse link
G Taf3 TATA-box binding protein associated factor 3 involved_in ISO (PMID:27007846) ComplexPortal PMID:27007846 NCBI chrNW_004955421:24,263,395...24,414,472 JBrowse link
G Taf4 TATA-box binding protein associated factor 4 involved_in ISO (PMID:27007846) ComplexPortal PMID:27007846 NCBI chrNW_004955528:1,951,952...2,020,592
Ensembl chrNW_004955528:1,994,249...2,020,494 		JBrowse link
G Taf5 TATA-box binding protein associated factor 5 involved_in ISO (PMID:27007846) ComplexPortal PMID:27007846 NCBI chrNW_004955485:7,159,199...7,176,269
Ensembl chrNW_004955485:7,160,022...7,175,608 		JBrowse link
G Taf6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:27007846) ComplexPortal PMID:27007846 NCBI chrNW_004955573:752,646...759,292
Ensembl chrNW_004955573:752,601...759,292 		JBrowse link
G Taf7 TATA-box binding protein associated factor 7 involved_in ISO (PMID:27007846) ComplexPortal PMID:27007846 NCBI chrNW_004955415:12,453,655...12,456,070
Ensembl chrNW_004955415:12,453,655...12,456,070 		JBrowse link
G Taf8 TATA-box binding protein associated factor 8 involved_in ISO (PMID:27007846) ComplexPortal PMID:27007846 NCBI chrNW_004955437:8,317,437...8,328,544
Ensembl chrNW_004955437:8,317,437...8,328,804 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in ISO (PMID:27007846) ComplexPortal PMID:27007846 NCBI chrNW_004955575:74,506...76,272
Ensembl chrNW_004955575:74,506...76,272 		JBrowse link
G Tbp TATA-box binding protein involved_in ISO (PMID:9841876)
(PMID:27007846)		 CAFA
ComplexPortal		 PMID:9841876 PMID:27007846 NCBI chrNW_004955411:3,268,147...3,285,567
Ensembl chrNW_004955411:3,268,147...3,285,077 		JBrowse link
transcription initiation-coupled chromatin remodeling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ash2l ASH2 like, histone lysine methyltransferase complex subunit involved_in ISO (PMID:19556245) UniProt PMID:19556245 NCBI chrNW_004955463:13,731,651...13,757,475
Ensembl chrNW_004955463:13,731,506...13,761,684 		JBrowse link
G Atf2 activating transcription factor 2 involved_in ISO (PMID:10821277) ARUK-UCL PMID:10821277 NCBI chrNW_004955449:332,563...411,218
Ensembl chrNW_004955449:338,193...411,218 		JBrowse link
G Brd7 bromodomain containing 7 involved_in ISO (PMID:20228809) UniProt PMID:20228809 NCBI chrNW_004955433:8,425,976...8,462,431
Ensembl chrNW_004955433:8,424,949...8,461,802 		JBrowse link
G Ctcfl CCCTC-binding factor like involved_in ISO (PMID:18765639) UniProt PMID:18765639 NCBI chrNW_004955445:1,944,845...1,969,502
Ensembl chrNW_004955445:1,944,789...1,970,484 		JBrowse link
G Dpy30 dpy-30 histone methyltransferase complex regulatory subunit involved_in ISO (PMID:19556245) UniProt PMID:19556245 NCBI chrNW_004955441:440,047...450,906
Ensembl chrNW_004955441:437,564...450,906 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:25818647), (PMID:27256286) ARUK-UCL PMID:25818647 PMID:27256286 NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933 		JBrowse link
G Glyr1 glyoxylate reductase 1 homolog involved_in ISO (PMID:30970244) UniProt PMID:30970244 NCBI chrNW_004955442:12,654,805...12,694,090
Ensembl chrNW_004955442:12,654,805...12,694,090 		JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISO (PMID:21856198)
(MGI:4946451|PMID:21149574)		 GO_Central
UniProt		 PMID:21149574 PMID:21856198 MGI:4946451 NCBI chrNW_004955451:11,770,201...11,802,992
Ensembl chrNW_004955451:11,770,201...11,802,992 		JBrowse link
G Kdm1b lysine demethylase 1B involved_in ISO (PMID:30970244) UniProt PMID:30970244 NCBI chrNW_004955483:8,000,862...8,052,486
Ensembl chrNW_004955483:8,002,577...8,052,486 		JBrowse link
G Kdm2a lysine demethylase 2A involved_in ISO (MGI:6694658|PMID:32584788) UniProt PMID:32584788 MGI:6694658 NCBI chrNW_004955422:18,201,243...18,308,163
Ensembl chrNW_004955422:18,200,758...18,308,163 		JBrowse link
G Kmt2a lysine methyltransferase 2A involved_in ISO (PMID:19556245)
(PMID:15960975)		 UniProt PMID:15960975 PMID:19556245 NCBI chrNW_004955412:19,586,435...19,670,149
Ensembl chrNW_004955412:19,586,141...19,665,527 		JBrowse link
G LOC102008188 core histone macro-H2A.1 involved_in ISO (PMID:25526730) UniProt PMID:25526730 NCBI chrNW_004955408:30,497,531...30,550,095
Ensembl chrNW_004955408:30,497,531...30,550,118 		JBrowse link
G Men1 menin 1 involved_in ISO (PMID:14992727)
(MGI:3035842|PMID:14992727)		 UniProt PMID:14992727 MGI:3035842 NCBI chrNW_004955422:20,356,491...20,363,374
Ensembl chrNW_004955422:20,356,491...20,363,575 		JBrowse link
G Myocd myocardin involved_in ISO (MGI:3525929|PMID:15601857) UniProt PMID:15601857 MGI:3525929 NCBI chrNW_004955467:4,653,065...4,743,438
Ensembl chrNW_004955467:4,656,380...4,743,110 		JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 involved_in ISO (PMID:31061526) UniProt PMID:31061526 NCBI chrNW_004955407:28,256,654...28,277,514
Ensembl chrNW_004955407:28,256,649...28,276,460 		JBrowse link
G Noc2l NOC2 like nucleolar associated transcriptional repressor involved_in ISO (PMID:16322561) GO_Central PMID:16322561 NCBI chrNW_004955486:9,750,969...9,763,622
Ensembl chrNW_004955486:9,751,053...9,767,104 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3 group C member 1 involved_in ISO PMID:12917342 UniProt PMID:12917342 RGD:8553888 NCBI chrNW_004955415:10,494,704...10,585,778
Ensembl chrNW_004955415:10,494,640...10,586,221 		JBrowse link
G Pabpc1l poly(A) binding protein cytoplasmic 1 like acts_upstream_of_or_within ISO (PMID:26134869) MGI PMID:26134869 NCBI chrNW_004955445:12,425,738...12,450,830
Ensembl chrNW_004955445:12,422,204...12,450,024 		JBrowse link
G Padi2 peptidyl arginine deiminase 2 involved_in ISO (PMID:22853951) UniProt PMID:22853951 NCBI chrNW_004955527:1,709,307...1,751,332
Ensembl chrNW_004955527:1,709,444...1,752,783 		JBrowse link
G Phf2 PHD finger protein 2 involved_in ISO (MGI:6716956|PMID:22921934) UniProt PMID:22921934 MGI:6716956 NCBI chrNW_004955515:4,428,068...4,471,642
Ensembl chrNW_004955515:4,429,957...4,471,641 		JBrowse link
G Rbbp5 RB binding protein 5, histone lysine methyltransferase complex subunit involved_in ISO (PMID:19556245) UniProt PMID:19556245 NCBI chrNW_004955406:40,868,290...40,904,343
Ensembl chrNW_004955406:40,867,527...40,904,349 		JBrowse link
G Sgf29 SAGA complex associated factor 29 involved_in ISO (PMID:23894581) UniProt PMID:23894581 NCBI chrNW_004955493:6,759,426...6,774,796
Ensembl chrNW_004955493:6,759,426...6,774,796 		JBrowse link
G Sirt7 sirtuin 7 involved_in ISO (PMID:28655758) UniProt PMID:28655758 NCBI chrNW_004955506:1,252,271...1,258,728
Ensembl chrNW_004955506:1,252,274...1,258,728 		JBrowse link
G Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 involved_in ISO (PMID:34910916) UniProt PMID:34910916 NCBI chrNW_004955495:2,021,671...2,105,155
Ensembl chrNW_004955495:2,021,566...2,105,397 		JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 involved_in ISO (PMID:22368283) UniProt PMID:22368283 NCBI chrNW_004955455:8,420,263...8,457,105
Ensembl chrNW_004955455:8,415,839...8,457,097 		JBrowse link
G Smarcd1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 involved_in ISO (PMID:12917342) UniProt PMID:12917342 NCBI chrNW_004955547:659,919...673,637
Ensembl chrNW_004955547:659,984...674,705 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in ISO (PMID:19729656) UniProt PMID:19729656 NCBI chrNW_004955559:1,921,479...1,929,450
Ensembl chrNW_004955559:1,917,301...1,928,493 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO (PMID:33951726)
(MGI:6508514|PMID:30171019)		 UniProt
ARUK-UCL		 PMID:30171019 PMID:33951726 MGI:6508514 NCBI chrNW_004955422:873,735...886,560
Ensembl chrNW_004955422:873,735...886,560 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:16322561) GO_Central PMID:16322561 NCBI chrNW_004955467:9,241,391...9,256,716
Ensembl chrNW_004955467:9,252,130...9,255,928 		JBrowse link
G Trmt112 tRNA methyltransferase activator subunit 11-2 involved_in ISO (PMID:31061526) UniProt PMID:31061526 NCBI chrNW_004955422:20,767,599...20,768,505
Ensembl chrNW_004955422:20,767,599...20,768,505 		JBrowse link
G Usp21 ubiquitin specific peptidase 21 involved_in ISO (MGI:3846030|PMID:18172164) UniProt PMID:18172164 MGI:3846030 NCBI chrNW_004955468:12,923,121...12,929,780
Ensembl chrNW_004955468:12,924,574...12,929,497 		JBrowse link
G Vps72 vacuolar protein sorting 72 homolog involved_in ISO (PMID:26974126) UniProt PMID:26974126 NCBI chrNW_004955588:537,122...550,564
Ensembl chrNW_004955588:536,788...551,241 		JBrowse link
G Wbp2 WW domain binding protein 2 involved_in ISO (PMID:23233354) UniProt PMID:23233354 NCBI chrNW_004955506:6,398,411...6,406,970
Ensembl chrNW_004955506:6,397,541...6,409,290 		JBrowse link
G Wdr5 WD repeat domain 5 involved_in ISO (PMID:19556245) UniProt PMID:19556245 NCBI chrNW_004955513:3,198,655...3,213,754
Ensembl chrNW_004955513:3,198,980...3,216,468 		JBrowse link
G Znhit1 zinc finger HIT-type containing 1 involved_in ISO (MGI:6287047|PMID:30842416), (MGI:7260820|PMID:35167494) UniProt PMID:30842416 PMID:35167494 MGI:6287047 MGI:7260820 NCBI chrNW_004955456:16,070,622...16,082,286
Ensembl chrNW_004955456:16,070,622...16,082,286 		JBrowse link
transcriptional start site selection at RNA polymerase II promoter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2b general transcription factor IIB involved_in ISO (PMID:10318856) UniProt PMID:10318856 NCBI chrNW_004955423:5,420,795...5,447,148
Ensembl chrNW_004955423:5,420,584...5,447,148 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12352
    metabolic process 7468
      organic substance metabolic process 7149
        macromolecule metabolic process 6004
          macromolecule biosynthetic process 4619
            RNA biosynthetic process 2271
              DNA-templated transcription initiation 130
                transcription initiation at RNA polymerase II promoter 108
                  RNA polymerase II preinitiation complex assembly + 25
                  negative regulation of transcription initiation by RNA polymerase II + 7
                  positive regulation of transcription initiation by RNA polymerase II + 45
                  regulation of transcription initiation by RNA polymerase II + 53
                  transcription initiation-coupled chromatin remodeling + 43
                  transcription open complex formation at RNA polymerase II promoter + 0
                  transcriptional start site selection at RNA polymerase II promoter + 2
Path 2
Term Annotations click to browse term
  biological_process 12352
    metabolic process 7468
      organic substance metabolic process 7149
        organic cyclic compound metabolic process 4094
          nucleobase-containing compound metabolic process 3737
            nucleic acid metabolic process 3370
              nucleic acid biosynthetic process 2380
                RNA biosynthetic process 2271
                  DNA-templated transcription 2249
                    DNA-templated transcription initiation 130
                      transcription initiation at RNA polymerase II promoter 108
                        RNA polymerase II preinitiation complex assembly + 25
                        negative regulation of transcription initiation by RNA polymerase II + 7
                        positive regulation of transcription initiation by RNA polymerase II + 45
                        regulation of transcription initiation by RNA polymerase II + 53
                        transcription initiation-coupled chromatin remodeling + 43
                        transcription open complex formation at RNA polymerase II promoter + 0
                        transcriptional start site selection at RNA polymerase II promoter + 2
paths to the root