Elob (elongin B) - Rat Genome Database

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Gene: Elob (elongin B) Chinchilla lanigera
Analyze
Symbol: Elob
Name: elongin B
RGD ID: 8873723
Description: ENCODES a protein that exhibits protein-containing complex binding (ortholog); transcription coactivator activity (ortholog); transcription corepressor binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); target-directed miRNA degradation (ortholog); transcription initiation at RNA polymerase II promoter (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); idiopathic generalized epilepsy (ortholog); FOUND IN Cul2-RING ubiquitin ligase complex (ortholog); Cul5-RING ubiquitin ligase complex (ortholog); elongin complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Tceb2; transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B); transcription elongation factor B polypeptide 2; transcription elongation factor B subunit 2
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,498,725 - 14,502,135 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544214,498,666 - 14,501,895 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Elob
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544214,498,725 - 14,502,135 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544214,498,666 - 14,501,895 (-)NCBIChiLan1.0ChiLan1.0
ELOB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38162,771,414 - 2,777,280 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl162,771,414 - 2,777,289 (-)EnsemblGRCh38hg38GRCh38
GRCh37162,821,415 - 2,827,281 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36162,761,416 - 2,767,298 (-)NCBINCBI36Build 36hg18NCBI36
Build 34162,761,416 - 2,767,298NCBI
Celera163,020,982 - 3,026,862 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef162,788,655 - 2,794,449 (-)NCBIHuRef
CHM1_1162,821,459 - 2,827,327 (-)NCBICHM1_1
T2T-CHM13v2.0162,791,632 - 2,797,493 (-)NCBIT2T-CHM13v2.0
Elob
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,043,714 - 24,048,083 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,043,712 - 24,048,110 (-)EnsemblGRCm39 Ensembl
GRCm381723,824,740 - 23,829,109 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1723,824,738 - 23,829,136 (-)EnsemblGRCm38mm10GRCm38
MGSCv371723,961,707 - 23,966,076 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361723,552,362 - 23,556,731 (-)NCBIMGSCv36mm8
Celera1724,319,126 - 24,323,354 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
Elob
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81013,353,413 - 13,358,484 (-)NCBIGRCr8
mRatBN7.21012,848,830 - 12,853,897 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1012,848,827 - 12,853,635 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1017,593,367 - 17,598,176 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,082,157 - 17,086,966 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01012,581,606 - 12,586,407 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01013,163,032 - 13,168,217 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,163,036 - 13,168,217 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01012,983,021 - 12,988,202 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,084,817 - 13,089,619 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,084,816 - 13,089,619 (-)NCBI
Celera1012,543,770 - 12,548,500 (-)NCBICelera
Cytogenetic Map10q12NCBI
LOC100994395
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29130,712,809 - 130,715,006 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111131,823,544 - 131,825,750 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011124,845,027 - 124,845,900 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111128,739,322 - 128,739,795 (-)NCBIpanpan1.1PanPan1.1panPan2
ELOB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,311,082 - 38,314,502 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,311,082 - 38,314,508 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha639,550,949 - 39,555,552 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0638,621,326 - 38,625,930 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1638,306,971 - 38,311,574 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,279,439 - 38,284,038 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0638,755,571 - 38,760,174 (-)NCBIUU_Cfam_GSD_1.0
Elob
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344105,408,280 - 105,412,743 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366941,296,782 - 1,300,149 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366941,296,304 - 1,301,183 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ELOB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,293,746 - 39,298,097 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,294,099 - 39,298,192 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2340,632,303 - 40,636,398 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ELOB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.152,564,662 - 2,570,035 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606828,342,826 - 28,349,254 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Elob
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624824590,334 - 596,494 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624824590,541 - 593,704 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000022175   ⟹   ENSCLAP00000021971
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544214,498,725 - 14,502,135 (-)Ensembl
RefSeq Acc Id: XM_005391402   ⟹   XP_005391459
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544214,498,666 - 14,501,895 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005391459 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000021971
  ENSCLAP00000021971.1
Reference Protein Sequences
RefSeq Acc Id: XP_005391459   ⟸   XM_005391402
- UniProtKB: A0A8C2W485 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000021971   ⟸   ENSCLAT00000022175
Protein Domains
Ubiquitin-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000015057 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000022175 ENTREZGENE
  ENSCLAT00000022175.1 UniProtKB/TrEMBL
InterPro ELOB UniProtKB/TrEMBL
  Ubiquitin-like_dom UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene LOC102015897 ENTREZGENE
PANTHER ELONGIN B UniProtKB/TrEMBL
  PTHR13248 UniProtKB/TrEMBL
Pfam ubiquitin UniProtKB/TrEMBL
PROSITE UBIQUITIN_2 UniProtKB/TrEMBL
SMART UBQ UniProtKB/TrEMBL
Superfamily-SCOP SSF54236 UniProtKB/TrEMBL
UniProt A0A8C2W485 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-11-08 Elob  elongin B  Tceb2  transcription elongation factor B subunit 2  Symbol and/or name change 5135510 APPROVED
2016-08-03 Tceb2  transcription elongation factor B subunit 2    transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)  Symbol and/or name change 5135510 APPROVED
2015-08-25 Tceb2  transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)  LOC102015897  transcription elongation factor B polypeptide 2-like  Symbol and/or name change 5135510 APPROVED