Taf1 (TATA-box binding protein associated factor 1) - Rat Genome Database

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Gene: Taf1 (TATA-box binding protein associated factor 1) Chinchilla lanigera
Analyze
Symbol: Taf1 (Ensembl: TAF1L)
Name: TATA-box binding protein associated factor 1
RGD ID: 8946359
Description: ENCODES a protein that exhibits acetyl-CoA binding (ortholog); DNA binding (ortholog); histone acetyltransferase activity (ortholog); INVOLVED IN cellular response to ATP (ortholog); cellular response to UV (ortholog); DNA damage response (ortholog); PARTICIPATES IN histone modification pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); autosomal hemophilia A (ortholog); FOUND IN chromatin (ortholog); MLL1 complex (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa; transcription initiation factor TFIID subunit 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547510,930,192 - 11,005,724 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547510,930,175 - 11,006,876 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Taf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547510,930,192 - 11,005,724 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495547510,930,175 - 11,006,876 (+)NCBIChiLan1.0ChiLan1.0
TAF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X71,366,357 - 71,530,525 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX71,366,136 - 71,532,374 (+)EnsemblGRCh38hg38GRCh38
GRCh37X70,586,207 - 70,750,375 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,502,839 - 70,601,025 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X70,369,134 - 70,467,321NCBI
CeleraX70,939,992 - 71,039,729 (+)NCBICelera
Cytogenetic MapXq13.1NCBI
HuRefX64,401,859 - 64,501,671 (+)NCBIHuRef
CHM1_1X70,479,138 - 70,579,043 (+)NCBICHM1_1
T2T-CHM13v2.0X69,800,459 - 69,963,776 (+)NCBIT2T-CHM13v2.0
Taf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X100,576,335 - 100,644,635 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX100,576,279 - 100,644,640 (+)EnsemblGRCm39 Ensembl
GRCm38X101,527,572 - 101,601,789 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX101,532,734 - 101,601,789 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X98,728,074 - 98,797,128 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X97,735,454 - 97,804,508 (+)NCBIMGSCv36mm8
CeleraX88,450,587 - 88,519,292 (+)NCBICelera
Cytogenetic MapXDNCBI
cM MapX44.29NCBI
Taf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X70,680,901 - 70,756,535 (+)NCBIGRCr8
mRatBN7.2X66,640,915 - 66,716,543 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX66,640,982 - 66,716,543 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX68,124,339 - 68,199,897 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X71,624,742 - 71,700,095 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X69,185,648 - 69,261,210 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X71,412,291 - 71,486,456 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX71,412,289 - 71,485,085 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X72,261,626 - 72,335,791 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X89,590,556 - 89,666,569 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX66,996,430 - 67,071,877 (+)NCBICelera
Cytogenetic MapXq22NCBI
TAF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X71,039,480 - 71,139,385 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X71,043,123 - 71,142,989 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X60,630,137 - 60,729,904 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X70,684,192 - 70,784,292 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX70,684,217 - 70,782,323 (+)Ensemblpanpan1.1panPan2
TAF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X55,693,091 - 55,764,268 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX55,693,194 - 55,763,683 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX46,519,902 - 46,591,035 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X56,662,169 - 56,733,328 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX56,662,183 - 56,732,743 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X54,629,611 - 54,700,758 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X55,961,540 - 56,032,713 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X55,888,952 - 55,960,089 (+)NCBIUU_Cfam_GSD_1.0
Taf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X46,427,534 - 46,509,580 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936762189,710 - 271,759 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX57,382,354 - 57,466,697 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X57,382,211 - 57,466,700 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TAF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X61,167,743 - 61,269,000 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX61,167,589 - 61,268,839 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660653,030,320 - 3,130,765 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Taf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249031,698,201 - 1,774,607 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000007127   ⟹   ENSCLAP00000007015
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547510,930,192 - 11,005,724 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000007128   ⟹   ENSCLAP00000007016
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547510,930,259 - 11,005,724 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000007129   ⟹   ENSCLAP00000007017
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547510,930,259 - 11,005,724 (+)Ensembl
Ensembl Acc Id: ENSCLAT00000007130   ⟹   ENSCLAP00000007018
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547510,930,259 - 11,005,724 (+)Ensembl
RefSeq Acc Id: XM_005401669   ⟹   XP_005401726
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547510,930,175 - 11,006,876 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005401670   ⟹   XP_005401727
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547510,930,177 - 11,006,876 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005401671   ⟹   XP_005401728
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547510,930,176 - 11,006,876 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013502870   ⟹   XP_013358324
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547510,930,177 - 11,006,876 (+)NCBI
Sequence:
RefSeq Acc Id: XP_005401728   ⟸   XM_005401671
- Peptide Label: isoform X3
- UniProtKB: A0A8C2UWX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005401726   ⟸   XM_005401669
- Peptide Label: isoform X1
- UniProtKB: A0A8C2V232 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005401727   ⟸   XM_005401670
- Peptide Label: isoform X2
- UniProtKB: A0A8C2UWX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013358324   ⟸   XM_013502870
- Peptide Label: isoform X4
- UniProtKB: A0A8C2V232 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000007015   ⟸   ENSCLAT00000007127
Ensembl Acc Id: ENSCLAP00000007018   ⟸   ENSCLAT00000007130
Ensembl Acc Id: ENSCLAP00000007016   ⟸   ENSCLAT00000007128
Ensembl Acc Id: ENSCLAP00000007017   ⟸   ENSCLAT00000007129
Protein Domains
Bromo


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004940 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007127 ENTREZGENE
  ENSCLAT00000007127.1 UniProtKB/TrEMBL
  ENSCLAT00000007128 ENTREZGENE
  ENSCLAT00000007128.1 UniProtKB/TrEMBL
  ENSCLAT00000007129.1 UniProtKB/TrEMBL
  ENSCLAT00000007130.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1100.10 UniProtKB/TrEMBL
  1.20.920.10 UniProtKB/TrEMBL
InterPro Bromodomain UniProtKB/TrEMBL
  Bromodomain-like_sf UniProtKB/TrEMBL
  Bromodomain_CS UniProtKB/TrEMBL
  TAF1 UniProtKB/TrEMBL
  TAF1_animal UniProtKB/TrEMBL
  TAF1_HAT_dom UniProtKB/TrEMBL
  TAF_II_230-bd UniProtKB/TrEMBL
  TAFII-230_TBP-bd_sf UniProtKB/TrEMBL
  Znf-CCHC_6 UniProtKB/TrEMBL
NCBI Gene Taf1 ENTREZGENE
PANTHER PTHR13900 UniProtKB/TrEMBL
  TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1 UniProtKB/TrEMBL
  TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1 UniProtKB/TrEMBL
Pfam Bromodomain UniProtKB/TrEMBL
  DUF3591 UniProtKB/TrEMBL
  TBP-binding UniProtKB/TrEMBL
  zf-CCHC_6 UniProtKB/TrEMBL
PIRSF TAF1_animal UniProtKB/TrEMBL
PRINTS BROMODOMAIN UniProtKB/TrEMBL
PROSITE BROMODOMAIN_1 UniProtKB/TrEMBL
  BROMODOMAIN_2 UniProtKB/TrEMBL
SMART BROMO UniProtKB/TrEMBL
Superfamily-SCOP SSF47055 UniProtKB/TrEMBL
  SSF47370 UniProtKB/TrEMBL
UniProt A0A8C2UWX8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2UWY6_CHILA UniProtKB/TrEMBL
  A0A8C2UXQ6_CHILA UniProtKB/TrEMBL
  A0A8C2V232 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-16 Taf1  TATA-box binding protein associated factor 1    TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa  Symbol and/or name change 5135510 APPROVED