Glyr1 (glyoxylate reductase 1 homolog) - Rat Genome Database

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Gene: Glyr1 (glyoxylate reductase 1 homolog) Chinchilla lanigera
Analyze
Symbol: Glyr1
Name: glyoxylate reductase 1 homolog
RGD ID: 8999303
Description: ENCODES a protein that exhibits chromatin binding (ortholog); chromatin-protein adaptor activity (ortholog); DNA binding (ortholog); INVOLVED IN transcription elongation-coupled chromatin remodeling (ortholog); transcription initiation-coupled chromatin remodeling (ortholog); ASSOCIATED WITH atrioventricular septal defect (ortholog); genetic disease (ortholog); Rubinstein-Taybi syndrome (ortholog); FOUND IN chromatin (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glyoxylate reductase 1 homolog (Arabidopsis); putative oxidoreductase GLYR1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544212,654,805 - 12,694,090 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544212,654,805 - 12,694,090 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
chromatin  (ISO)
cytosol  (ISO)
nucleoplasm  (ISO)
nucleosome  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Glyr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544212,654,805 - 12,694,090 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544212,654,805 - 12,694,090 (+)NCBIChiLan1.0ChiLan1.0
GLYR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38164,803,203 - 4,847,288 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl164,803,203 - 4,847,288 (-)EnsemblGRCh38hg38GRCh38
GRCh37164,853,204 - 4,897,289 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36164,793,205 - 4,837,285 (-)NCBINCBI36Build 36hg18NCBI36
Celera165,061,974 - 5,106,076 (-)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef164,819,402 - 4,863,584 (-)NCBIHuRef
CHM1_1164,854,050 - 4,898,201 (-)NCBICHM1_1
T2T-CHM13v2.0164,832,757 - 4,876,778 (-)NCBIT2T-CHM13v2.0
Glyr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,831,766 - 4,867,780 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl164,831,773 - 4,867,727 (-)EnsemblGRCm39 Ensembl
GRCm38165,013,902 - 5,049,938 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl165,013,909 - 5,049,863 (-)EnsemblGRCm38mm10GRCm38
MGSCv37165,013,995 - 5,050,003 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36164,929,258 - 4,965,170 (-)NCBIMGSCv36mm8
Celera165,645,276 - 5,681,247 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map162.49NCBI
Glyr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81011,038,577 - 11,074,093 (+)NCBIGRCr8
mRatBN7.21010,532,036 - 10,567,639 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1010,532,154 - 10,567,637 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1015,240,171 - 15,273,873 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01014,728,991 - 14,762,692 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01010,398,277 - 10,431,933 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01010,725,830 - 10,759,471 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1010,725,819 - 10,761,279 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0109,492,794 - 9,528,295 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41010,648,082 - 10,681,723 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11010,648,081 - 10,681,723 (+)NCBI
Celera109,495,963 - 9,529,604 (+)NCBICelera
Cytogenetic Map10q12NCBI
GLYR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2185,331,400 - 5,375,699 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1169,121,553 - 9,165,856 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0163,727,358 - 3,771,554 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1164,892,827 - 4,936,615 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl164,892,827 - 4,936,615 (-)Ensemblpanpan1.1panPan2
GLYR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1636,582,438 - 36,618,265 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl636,582,461 - 36,616,206 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha637,974,709 - 38,010,518 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0636,785,395 - 36,821,238 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl636,785,359 - 36,821,238 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1636,579,988 - 36,615,294 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0636,472,906 - 36,508,177 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0636,874,580 - 36,910,393 (+)NCBIUU_Cfam_GSD_1.0
Glyr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344106,916,484 - 106,948,692 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365304,761,823 - 4,794,729 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365304,761,838 - 4,794,191 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLYR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl337,555,394 - 37,593,559 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1337,555,357 - 37,593,492 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2338,626,413 - 38,664,624 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GLYR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.154,473,222 - 4,518,150 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl54,475,227 - 4,518,071 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606826,140,241 - 26,186,300 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Glyr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248242,655,909 - 2,692,522 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248242,655,909 - 2,692,546 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000022088   ⟹   ENSCLAP00000021884
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544212,654,805 - 12,694,090 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000022089   ⟹   ENSCLAP00000021885
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495544212,655,561 - 12,692,241 (+)Ensembl
RefSeq Acc Id: XM_005391261   ⟹   XP_005391318
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544212,654,805 - 12,694,090 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005391262   ⟹   XP_005391319
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544212,654,805 - 12,694,090 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005391263   ⟹   XP_005391320
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544212,654,805 - 12,694,090 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005391264   ⟹   XP_005391321
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495544212,654,805 - 12,686,320 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005391318 (Get FASTA)   NCBI Sequence Viewer  
  XP_005391319 (Get FASTA)   NCBI Sequence Viewer  
  XP_005391320 (Get FASTA)   NCBI Sequence Viewer  
  XP_005391321 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000021884
  ENSCLAP00000021884.1
  ENSCLAP00000021885.1
RefSeq Acc Id: XP_005391321   ⟸   XM_005391264
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005391320   ⟸   XM_005391263
- Peptide Label: isoform X3
- UniProtKB: A0A8C2W4P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005391318   ⟸   XM_005391261
- Peptide Label: isoform X1
- UniProtKB: A0A8C2W4P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005391319   ⟸   XM_005391262
- Peptide Label: isoform X2
- UniProtKB: A0A8C2W4P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000021885   ⟸   ENSCLAT00000022089
RefSeq Acc Id: ENSCLAP00000021884   ⟸   ENSCLAT00000022088
Protein Domains
PWWP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000014997 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000022088 ENTREZGENE
  ENSCLAT00000022088.1 UniProtKB/TrEMBL
  ENSCLAT00000022089.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.140 UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro 6-PGluconate_DH-like_C_sf UniProtKB/TrEMBL
  6PGD_dom2 UniProtKB/TrEMBL
  6PGDH_NADP-bd UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  NADP-bd UniProtKB/TrEMBL
  NP60_PWWP UniProtKB/TrEMBL
  PWWP_dom UniProtKB/TrEMBL
NCBI Gene Glyr1 ENTREZGENE
PANTHER OXIDOREDUCTASE GLYR1-RELATED UniProtKB/TrEMBL
  OXIDOREDUCTASE GLYR1-RELATED UniProtKB/TrEMBL
Pfam NAD_binding_11 UniProtKB/TrEMBL
  NAD_binding_2 UniProtKB/TrEMBL
  PWWP UniProtKB/TrEMBL
PROSITE PWWP UniProtKB/TrEMBL
SMART PWWP UniProtKB/TrEMBL
Superfamily-SCOP SSF48179 UniProtKB/TrEMBL
  SSF51735 UniProtKB/TrEMBL
  Tudor/PWWP/MBT UniProtKB/TrEMBL
UniProt A0A8C2VZ85_CHILA UniProtKB/TrEMBL
  A0A8C2W4P3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Glyr1  glyoxylate reductase 1 homolog    glyoxylate reductase 1 homolog (Arabidopsis)  Symbol and/or name change 5135510 APPROVED