N6amt1 (N-6 adenine-specific DNA methyltransferase 1) - Rat Genome Database

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Gene: N6amt1 (N-6 adenine-specific DNA methyltransferase 1) Chinchilla lanigera
Analyze
Symbol: N6amt1
Name: N-6 adenine-specific DNA methyltransferase 1
RGD ID: 8720686
Description: ENCODES a protein that exhibits histone H4K12 methyltransferase activity (ortholog); methylarsonite methyltransferase activity (ortholog); protein methyltransferase activity (ortholog); INVOLVED IN arsonoacetate metabolic process (ortholog); methylation (ortholog); negative regulation of gene expression, epigenetic (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleus (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: hemK methyltransferase family member 2; N-6 adenine-specific DNA methyltransferase 1 (putative)
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540728,256,649 - 28,276,460 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540728,256,654 - 28,277,514 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
N6amt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540728,256,649 - 28,276,460 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540728,256,654 - 28,277,514 (+)NCBIChiLan1.0ChiLan1.0
N6AMT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382128,575,598 - 28,885,367 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2128,872,191 - 28,885,371 (-)EnsemblGRCh38hg38GRCh38
GRCh372130,244,513 - 30,257,689 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362129,166,384 - 29,179,564 (-)NCBINCBI36Build 36hg18NCBI36
Celera2115,427,774 - 15,440,965 (-)NCBICelera
Cytogenetic Map21q21.3NCBI
HuRef2115,649,537 - 15,662,924 (-)NCBIHuRef
CHM1_12129,806,890 - 29,820,072 (-)NCBICHM1_1
T2T-CHM13v2.02127,235,374 - 27,248,586 (-)NCBIT2T-CHM13v2.0
N6amt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391687,151,073 - 87,165,537 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1687,151,073 - 87,165,630 (+)EnsemblGRCm39 Ensembl
GRCm381687,354,185 - 87,368,649 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1687,354,185 - 87,368,742 (+)EnsemblGRCm38mm10GRCm38
MGSCv371687,354,430 - 87,368,894 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361687,243,381 - 87,257,845 (+)NCBIMGSCv36mm8
Celera1687,539,465 - 87,553,925 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1649.52NCBI
N6amt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81140,071,017 - 40,083,463 (+)NCBIGRCr8
mRatBN7.21126,584,750 - 26,597,790 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1126,584,724 - 26,608,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1135,282,689 - 35,295,029 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01127,982,937 - 27,995,276 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01127,171,867 - 27,184,209 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01127,004,335 - 27,016,690 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,004,320 - 27,016,941 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01130,629,574 - 30,641,929 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41127,107,106 - 27,119,552 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11127,107,109 - 27,119,546 (+)NCBI
Celera1126,337,923 - 26,356,638 (+)NCBICelera
Cytogenetic Map11q11NCBI
N6AMT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22224,764,439 - 25,067,011 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12119,621,921 - 19,925,542 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02115,303,430 - 15,316,596 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12128,691,847 - 28,704,745 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2128,694,294 - 28,704,745 (-)Ensemblpanpan1.1panPan2
N6AMT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13123,895,558 - 23,934,183 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3123,895,584 - 23,909,940 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3123,888,155 - 23,926,785 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03124,008,039 - 24,046,658 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13123,959,405 - 23,997,823 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03123,961,154 - 23,999,634 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03124,432,448 - 24,471,137 (+)NCBIUU_Cfam_GSD_1.0
N6amt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497124,368,003 - 24,381,211 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650013,084,595 - 13,099,844 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650013,086,873 - 13,099,814 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
N6AMT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13192,249,246 - 192,265,629 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113192,248,511 - 192,265,923 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213202,558,051 - 202,782,210 (+)NCBISscrofa10.2Sscrofa10.2susScr3
N6AMT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1263,348,897 - 63,363,709 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl263,348,745 - 63,363,090 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660715,935,090 - 5,950,770 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
N6amt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474516,908,686 - 16,920,351 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474516,908,683 - 16,922,941 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000014292   ⟹   ENSCLAP00000014134
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540728,256,649 - 28,276,460 (+)Ensembl
RefSeq Acc Id: XM_005375604   ⟹   XP_005375661
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540728,256,654 - 28,276,460 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005375607   ⟹   XP_005375664
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540728,256,654 - 28,276,460 (+)NCBI
Sequence:
RefSeq Acc Id: XR_259592
Type: NON-CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540728,256,654 - 28,277,514 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005375661 (Get FASTA)   NCBI Sequence Viewer  
  XP_005375664 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000014134
  ENSCLAP00000014134.1
Reference Protein Sequences
RefSeq Acc Id: XP_005375661   ⟸   XM_005375604
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VDX3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005375664   ⟸   XM_005375607
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000014134   ⟸   ENSCLAT00000014292
Protein Domains
Methyltransferase small


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000009758 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000014292 ENTREZGENE
  ENSCLAT00000014292.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
InterPro DNA_methylase_N6_adenine_CS UniProtKB/TrEMBL
  PrmC-related UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
  Small_mtfrase_dom UniProtKB/TrEMBL
NCBI Gene LOC102023329 ENTREZGENE
PANTHER METHYLTRANSFERASE N6AMT1 UniProtKB/TrEMBL
  METHYLTRANSFERASE N6AMT1 UniProtKB/TrEMBL
Pfam MTS UniProtKB/TrEMBL
PROSITE N6_MTASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A8C2VDX3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-15 N6amt1  N-6 adenine-specific DNA methyltransferase 1    N-6 adenine-specific DNA methyltransferase 1 (putative)  Symbol and/or name change 5135510 APPROVED
2015-08-25 N6amt1  N-6 adenine-specific DNA methyltransferase 1 (putative)  LOC102023329  hemK methyltransferase family member 2-like  Symbol and/or name change 5135510 APPROVED