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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of transcription initiation from RNA polymerase II promoter
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Accession:GO:0060260 term browser browse the term
Definition:Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.

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negative regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:8006019) RGD PMID:8006019 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237 		JBrowse link
G Thra thyroid hormone receptor alpha involved_in IEA
ISO		 GO_REF:0000107
(PMID:8524305)		 Ensembl
RGD		 PMID:8524305 GO_REF:0000107 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933 		JBrowse link
negative regulation of transcription initiation from RNA polymerase II promoter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnbip1 catenin, beta-interacting protein 1 involved_in ISO (MGI:4821083|PMID:11751639) RGD PMID:11751639 MGI:4821083 NCBI chr 5:166,464,170...166,513,030
Ensembl chr 5:166,464,252...166,513,027 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (PMID:10692439) RGD PMID:10692439 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531 		JBrowse link
G Zfp451 zinc finger protein 451 involved_in ISO (PMID:24324267) RGD PMID:24324267 NCBI chr 9:38,395,464...38,451,585
Ensembl chr 9:38,396,449...38,451,656 		JBrowse link
positive regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor acts_upstream_of_or_within ISO (MGI:62922|PMID:8215422) RGD PMID:8215422 MGI:62922 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464 		JBrowse link
G Cand1 cullin-associated and neddylation-dissociated 1 involved_in IDA PMID:10567521 UniProt PMID:10567521 RGD:8553447 NCBI chr 7:62,124,362...62,162,451
Ensembl chr 7:62,124,362...62,162,453 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 IMP RGD PMID:16891311 RGD:1625706 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435 		JBrowse link
G Esr1 estrogen receptor 1 involved_in ISO
IEA		 (PMID:9841876)
GO_REF:0000107		 RGD
Ensembl		 PMID:9841876 GO_REF:0000107 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO MGI:2158690 (MGI:5317044|PMID:21245044) RGD PMID:21245044 MGI:5317044 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424 		JBrowse link
G Psmc2 proteasome 26S subunit, ATPase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:9,867,132...9,881,383
Ensembl chr 4:9,867,101...9,881,484 		JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:79,876,938...79,882,319
Ensembl chr 3:79,876,938...79,882,319 		JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:84,978,220...84,986,536
Ensembl chr 1:84,978,206...84,986,581 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:94,445,877...94,451,811
Ensembl chr10:94,445,877...94,451,811 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:24289924) RGD PMID:24289924 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Wnt10b Wnt family member 10B acts_upstream_of_or_within ISO (MGI:3820325|PMID:19056892) RGD PMID:19056892 MGI:3820325 NCBI chr 7:140,448,284...140,466,159
Ensembl chr 7:140,448,465...140,454,268 		JBrowse link
positive regulation of transcription initiation from RNA polymerase II promoter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx36 DEAH-box helicase 36 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21993297)		 UniProt
RGD		 PMID:21993297 GO_REF:0000024 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit acts_upstream_of_or_within ISO (MGI:5314556|PMID:22323595) RGD PMID:22323595 MGI:5314556 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO MGI:1932102|MGI:99135 (MGI:5314556|PMID:22323595) RGD PMID:22323595 MGI:5314556 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610 		JBrowse link
G Hnf1a HNF1 homeobox A involved_in ISO UniProtKB:P35680 (PMID:15355349) RGD PMID:15355349 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342 		JBrowse link
G Hnf1b HNF1 homeobox B involved_in ISO (PMID:15355349) RGD PMID:15355349 NCBI chr10:71,159,863...71,218,902
Ensembl chr10:71,159,869...71,218,902 		JBrowse link
G Irf8 interferon regulatory factor 8 acts_upstream_of_or_within
NOT|acts_upstream_of_or_within		 ISO (MGI:5448615|PMID:22942423) RGD PMID:22942423 MGI:5448615 NCBI chr19:54,314,859...54,336,643
Ensembl chr19:54,314,865...54,336,640 		JBrowse link
G Med1 mediator complex subunit 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12218053), (PMID:16314496)		 UniProt
RGD		 PMID:12218053 PMID:16314496 GO_REF:0000024 NCBI chr10:86,101,560...86,145,271
Ensembl chr10:86,103,600...86,144,880 		JBrowse link
G Med12 mediator complex subunit 12 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr  X:71,174,653...71,197,812
Ensembl chr  X:71,174,699...71,197,812 		JBrowse link
G Med13 mediator complex subunit 13 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr10:73,702,327...73,787,084
Ensembl chr10:73,702,327...73,787,083 		JBrowse link
G Med14 mediator complex subunit 14 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr  X:10,964,035...11,082,403
Ensembl chr  X:10,963,809...11,082,565 		JBrowse link
G Med16 mediator complex subunit 16 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr 7:12,619,739...12,632,241
Ensembl chr 7:12,542,713...12,632,298 		JBrowse link
G Med17 mediator complex subunit 17 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr 8:13,522,257...13,835,302
Ensembl chr 8:13,819,563...13,835,168 		JBrowse link
G Med24 mediator complex subunit 24 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr10:86,620,166...86,658,014
Ensembl chr10:86,620,160...86,645,529 		JBrowse link
G Med30 mediator complex subunit 30 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr 7:92,234,584...92,260,019
Ensembl chr 7:92,234,597...92,256,100 		JBrowse link
G Med4 mediator complex subunit 4 involved_in ISO (PMID:12218053) RGD PMID:12218053 NCBI chr15:55,406,543...55,416,816
Ensembl chr15:55,406,543...55,416,815 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (MGI:6377809|PMID:26691508) RGD PMID:26691508 MGI:6377809 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Nkx2-5 NK2 homeobox 5 involved_in IEA
ISO		 GO_REF:0000107
(MGI:83559|PMID:8887666)		 Ensembl
RGD		 PMID:8887666 GO_REF:0000107 MGI:83559 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764 		JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:17925232)
(MGI:4354659|PMID:19583951), (MGI:4821506|PMID:20671152)		 RGD PMID:17925232 PMID:19583951 PMID:20671152 MGI:4354659 MGI:4821506 NCBI chr 4:3,956,931...4,008,326
Ensembl chr 4:3,959,640...4,008,326 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 involved_in ISO (MGI:6377809|PMID:26691508) RGD PMID:26691508 MGI:6377809 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994 		JBrowse link
G Srf serum response factor involved_in ISO (PMID:8887666) RGD PMID:8887666 NCBI chr 9:16,737,637...16,747,226
Ensembl chr 9:16,737,642...16,747,225 		JBrowse link
G Sub1 SUB1 regulator of transcription involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:62,019,902...62,034,704
Ensembl chr 2:62,022,567...62,034,628 		JBrowse link
G Taf6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:11583621), (PMID:18628956) RGD PMID:11583621 PMID:18628956 NCBI chr12:19,320,269...19,328,706
Ensembl chr12:19,320,271...19,328,637 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor acts_upstream_of_or_within ISO MGI:1100494 (MGI:5314556|PMID:22323595) RGD PMID:22323595 MGI:5314556 NCBI chr 5:61,749,767...61,793,641
Ensembl chr 5:61,749,767...61,792,928 		JBrowse link
regulation of RNA polymerase II transcription preinitiation complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf7ip activating transcription factor 7 interacting protein involved_in ISO (PMID:12665582) RGD PMID:12665582 NCBI chr 4:170,476,998...170,563,063
Ensembl chr 4:170,518,673...170,559,532 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    metabolic process 11911
      regulation of metabolic process 6824
        regulation of macromolecule metabolic process 6310
          regulation of gene expression 4799
            regulation of transcription, DNA-templated 3271
              regulation of transcription by RNA polymerase II 2387
                regulation of transcription initiation from RNA polymerase II promoter 41
                  negative regulation of transcription initiation from RNA polymerase II promoter + 5
                  positive regulation of transcription initiation from RNA polymerase II promoter + 35
                  regulation of RNA polymerase II transcription preinitiation complex assembly + 15
                  regulation of transcriptional start site selection at RNA polymerase II promoter 0
Path 2
Term Annotations click to browse term
  biological_process 19634
    metabolic process 11911
      cellular metabolic process 10866
        cellular aromatic compound metabolic process 5616
          nucleobase-containing compound metabolic process 5404
            nucleic acid metabolic process 4915
              RNA metabolic process 4400
                RNA biosynthetic process 3419
                  nucleic acid-templated transcription 3404
                    transcription, DNA-templated 3402
                      regulation of transcription, DNA-templated 3271
                        regulation of DNA-templated transcription, initiation 50
                          regulation of transcription initiation from RNA polymerase II promoter 41
                            negative regulation of transcription initiation from RNA polymerase II promoter + 5
                            positive regulation of transcription initiation from RNA polymerase II promoter + 35
                            regulation of RNA polymerase II transcription preinitiation complex assembly + 15
                            regulation of transcriptional start site selection at RNA polymerase II promoter 0
paths to the root