Gtf2a1 (general transcription factor IIA subunit 1) - Rat Genome Database

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Gene: Gtf2a1 (general transcription factor IIA subunit 1) Chinchilla lanigera
Analyze
Symbol: Gtf2a1
Name: general transcription factor IIA subunit 1
RGD ID: 8927771
Description: ENCODES a protein that exhibits DNA binding (ortholog); protein heterodimerization activity (ortholog); RNA polymerase II core promoter sequence-specific DNA binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription initiation by RNA polymerase II (ortholog); transcription by RNA polymerase II (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: general transcription factor IIA, 1, 19/37kDa; transcription initiation factor IIA subunit 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554384,787,190 - 4,825,577 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554384,787,190 - 4,825,578 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Gtf2a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554384,787,190 - 4,825,577 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554384,787,190 - 4,825,578 (-)NCBIChiLan1.0ChiLan1.0
GTF2A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381481,175,452 - 81,221,390 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1481,175,452 - 81,221,377 (-)EnsemblGRCh38hg38GRCh38
GRCh371481,641,796 - 81,687,734 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361480,716,147 - 80,757,328 (-)NCBINCBI36Build 36hg18NCBI36
Build 341480,716,146 - 80,757,328NCBI
Celera1461,686,296 - 61,727,496 (-)NCBICelera
Cytogenetic Map14q31.1NCBI
HuRef1461,809,402 - 61,855,401 (-)NCBIHuRef
CHM1_11481,582,217 - 81,627,845 (-)NCBICHM1_1
T2T-CHM13v2.01475,387,683 - 75,433,560 (-)NCBIT2T-CHM13v2.0
Gtf2a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391291,522,036 - 91,559,102 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1291,522,036 - 91,557,261 (-)EnsemblGRCm39 Ensembl
GRCm381291,555,262 - 91,590,487 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1291,555,262 - 91,590,487 (-)EnsemblGRCm38mm10GRCm38
MGSCv371292,793,702 - 92,828,927 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361291,964,272 - 91,996,044 (-)NCBIMGSCv36mm8
Celera1292,856,544 - 92,892,065 (-)NCBICelera
Cytogenetic Map12D3NCBI
cM Map1245.02NCBI
Gtf2a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86116,219,614 - 116,252,220 (-)NCBIGRCr8
mRatBN7.26110,488,891 - 110,521,502 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6110,488,931 - 110,521,511 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6110,632,610 - 110,660,371 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06110,931,266 - 110,959,022 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06110,305,967 - 110,333,614 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06115,321,110 - 115,352,659 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6115,320,467 - 115,352,681 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06124,576,129 - 124,607,638 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46115,180,871 - 115,210,825 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16115,184,401 - 115,214,356 (-)NCBI
Celera6108,243,380 - 108,271,421 (-)NCBICelera
Cytogenetic Map6q31NCBI
GTF2A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21582,285,120 - 82,330,430 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11481,501,625 - 81,546,928 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01461,751,492 - 61,797,083 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11480,951,886 - 80,996,777 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1480,951,886 - 80,996,777 (-)Ensemblpanpan1.1panPan2
GTF2A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1853,520,740 - 53,568,888 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl853,524,787 - 53,568,705 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha853,078,908 - 53,125,623 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0853,750,721 - 53,797,167 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl853,750,104 - 53,797,236 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1853,432,356 - 53,478,683 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0853,436,154 - 53,482,553 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0853,828,585 - 53,875,047 (-)NCBIUU_Cfam_GSD_1.0
Gtf2a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864022,433,469 - 22,472,544 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364889,600,465 - 9,630,310 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364889,595,344 - 9,630,357 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTF2A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7103,963,248 - 104,009,226 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17103,963,863 - 104,009,318 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27109,961,234 - 109,992,442 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GTF2A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12458,506,888 - 58,552,587 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2458,506,537 - 58,551,069 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605346,230,975 - 46,277,956 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gtf2a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473420,795,474 - 20,831,234 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473420,795,550 - 20,830,602 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000011291   ⟹   ENSCLAP00000011155
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554384,787,190 - 4,825,577 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000011292   ⟹   ENSCLAP00000011156
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554384,791,781 - 4,821,702 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000011293   ⟹   ENSCLAP00000011157
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554384,791,783 - 4,825,115 (-)Ensembl
RefSeq Acc Id: XM_005390236   ⟹   XP_005390293
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554384,787,190 - 4,825,577 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005390237   ⟹   XP_005390294
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554384,787,190 - 4,825,578 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013517226   ⟹   XP_013372680
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554384,787,190 - 4,825,577 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005390293 (Get FASTA)   NCBI Sequence Viewer  
  XP_005390294 (Get FASTA)   NCBI Sequence Viewer  
  XP_013372680 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000011155
  ENSCLAP00000011155.1
  ENSCLAP00000011156.1
  ENSCLAP00000011157
  ENSCLAP00000011157.1
RefSeq Acc Id: XP_005390294   ⟸   XM_005390237
- Peptide Label: isoform X2
- UniProtKB: A0A8C2VBZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005390293   ⟸   XM_005390236
- Peptide Label: isoform X1
- UniProtKB: A0A8C2VBZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013372680   ⟸   XM_013517226
- Peptide Label: isoform X3
- UniProtKB: A0A8C2V962 (UniProtKB/TrEMBL),   A0A8C2VBZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000011157   ⟸   ENSCLAT00000011293
RefSeq Acc Id: ENSCLAP00000011156   ⟸   ENSCLAT00000011292
RefSeq Acc Id: ENSCLAP00000011155   ⟸   ENSCLAT00000011291


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000007709 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000011291 ENTREZGENE
  ENSCLAT00000011291.1 UniProtKB/TrEMBL
  ENSCLAT00000011292.1 UniProtKB/TrEMBL
  ENSCLAT00000011293 ENTREZGENE
  ENSCLAT00000011293.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.100 UniProtKB/TrEMBL
  2.30.18.10 UniProtKB/TrEMBL
InterPro TFIIA_asu/bsu UniProtKB/TrEMBL
  TFIIA_b-brl UniProtKB/TrEMBL
NCBI Gene Gtf2a1 ENTREZGENE
PANTHER PTHR12694 UniProtKB/TrEMBL
  TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 UniProtKB/TrEMBL
Pfam TFIIA UniProtKB/TrEMBL
SMART TFIIA UniProtKB/TrEMBL
Superfamily-SCOP SSF50784 UniProtKB/TrEMBL
  Transcription factor IIA (TFIIA), alpha-helical domain UniProtKB/TrEMBL
UniProt A0A8C2V6V5_CHILA UniProtKB/TrEMBL
  A0A8C2V962 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C2VBZ7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Gtf2a1  general transcription factor IIA subunit 1    general transcription factor IIA, 1, 19/37kDa  Symbol and/or name change 5135510 APPROVED