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ONTOLOGY REPORT - ANNOTATIONS

Term:calcium channel activity
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Accession:GO:0005262 term browser browse the term
Definition:Enables the energy-independent facilitated diffusion of a calcium ion through a transmembrane aqueous pore or channel.
Synonyms:xref: Reactome:R-HSA-9663785 "CHRNA9:CHRNA10:AcCho transports Ca2+ from the extracellular region to the cytosol";   reactome:R-HSA-139854 "IP3R tetramer:I(1,4,5)P3:4xCa2+ transports Ca2+ from platelet dense tubular system to cytosol";   reactome:R-HSA-139855 "P2X1-mediated entry of Ca++ from plasma";   reactome:R-HSA-210420 "Ca2+ influx through voltage gated Ca2+ channels";   reactome:R-HSA-3295579 "TRPs transport extracellular Ca2+ to cytosol";   reactome:R-HSA-8949145 "VDAC1,2,3 translocate calcium from the cytosol to the mitochondrial intermembrane space";   reactome:R-HSA-8949178 "MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix"


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calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr30:25,176,845...25,210,244
Ensembl chr30:25,115,842...25,218,281 		JBrowse link
G ANXA6 annexin A6 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 4:58,091,186...58,140,102
Ensembl chr 4:58,091,251...58,139,372 		JBrowse link
G ANXA9 annexin A9 enables IEA TreeGrafter GO_REF:0000118 NCBI chr17:60,084,296...60,098,631
Ensembl chr17:60,084,241...60,094,136 		JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A enables IEA UniProt GO_REF:0000043 NCBI chr20:48,747,087...49,036,627
Ensembl chr20:48,821,025...49,036,032 		JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B enables IEA UniProt GO_REF:0000043 NCBI chr 9:47,813,625...48,009,532
Ensembl chr 9:47,816,393...48,009,406 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C enables IEA UniProt GO_REF:0000043 NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D enables IEA UniProt
Ensembl		 GO_REF:0000043 GO_REF:0000107 NCBI chr20:36,189,986...36,488,460
Ensembl chr20:36,191,810...36,613,686 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E enables IEA UniProt GO_REF:0000043 NCBI chr 7:14,892,165...15,267,418
Ensembl chr 7:14,707,801...15,267,422 		JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F enables IEA UniProt GO_REF:0000043 NCBI chr  X:42,302,971...42,327,787
Ensembl chr  X:42,303,158...42,326,774 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G enables IEA UniProt GO_REF:0000043 NCBI chr 9:26,481,148...26,544,511
Ensembl chr 9:26,481,652...26,544,845 		JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I enables IEA UniProt GO_REF:0000043 NCBI chr10:25,381,446...25,493,680
Ensembl chr10:25,380,943...25,482,852 		JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S enables IEA UniProt GO_REF:0000043 NCBI chr 7:2,108,716...2,172,246
Ensembl chr 7:2,108,455...2,303,220 		JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 enables IEA UniProt GO_REF:0000043 NCBI chr18:21,561,091...21,949,970
Ensembl chr18:21,564,676...21,949,544 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 enables IEA UniProt GO_REF:0000043 NCBI chr20:38,859,047...38,995,239
Ensembl chr20:38,883,530...38,993,273 		JBrowse link
G CACNA2D3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 enables IEA UniProt GO_REF:0000043 NCBI chr20:35,097,185...36,043,562
Ensembl chr20:35,097,182...35,956,774 		JBrowse link
G CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 enables IEA UniProt GO_REF:0000043 NCBI chr27:43,840,190...43,961,067
Ensembl chr27:43,844,529...44,041,637 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 enables IEA UniProt GO_REF:0000043 NCBI chr 9:23,182,407...23,197,035
Ensembl chr 9:23,180,554...23,195,673 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 enables IEA UniProt GO_REF:0000043 NCBI chr 2:18,537,100...18,787,728
Ensembl chr 2:18,538,620...18,902,286 		JBrowse link
G CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 enables IEA UniProt GO_REF:0000043 NCBI chr 9:13,425,898...13,438,275
Ensembl chr 9:13,426,105...13,438,614 		JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 enables IEA UniProt GO_REF:0000043 NCBI chr10:27,750,314...27,862,646
Ensembl chr10:27,750,935...27,862,885 		JBrowse link
G CACNG3 calcium voltage-gated channel auxiliary subunit gamma 3 enables IEA UniProt GO_REF:0000043 NCBI chr 6:21,626,977...21,712,331
Ensembl chr 6:21,627,547...21,711,635 		JBrowse link
G CACNG6 calcium voltage-gated channel auxiliary subunit gamma 6 enables IEA UniProt GO_REF:0000043 NCBI chr 1:103,227,936...103,244,263
Ensembl chr 1:103,226,597...103,244,441 		JBrowse link
G CACNG7 calcium voltage-gated channel auxiliary subunit gamma 7 enables IEA UniProt GO_REF:0000043 NCBI chr 1:103,276,743...103,293,393
Ensembl chr 1:103,277,662...103,293,995 		JBrowse link
G CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 enables IEA UniProt GO_REF:0000043 NCBI chr 1:103,245,102...103,263,154
Ensembl chr 1:103,250,132...103,263,178 		JBrowse link
G CNGA1 cyclic nucleotide gated channel subunit alpha 1 enables IEA UniProt GO_REF:0000043 NCBI chr13:43,831,159...43,864,276
Ensembl chr13:43,831,163...43,864,276 		JBrowse link
G DCP1B decapping mRNA 1B enables IEA UniProt GO_REF:0000043 NCBI chr27:43,987,778...44,041,661
Ensembl chr27:43,844,529...44,041,637 		JBrowse link
G FAM98C family with sequence similarity 98 member C enables IEA UniProt GO_REF:0000043 NCBI chr 1:114,598,841...114,602,316
Ensembl chr 1:114,597,464...114,602,708 		JBrowse link
G GPM6A glycoprotein M6A ISO RGD PMID:12359212 RGD:708586 NCBI chr16:53,697,830...53,846,773
Ensembl chr16:53,698,043...53,845,259 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 contributes_to
enables		 ISO (PMID:7685113)
(PMID:1374164)		 UniProtKB
MGI		 PMID:1374164 PMID:7685113 NCBI chr 9:48,492,967...48,513,981
Ensembl chr 9:48,493,287...48,509,050 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A enables
contributes_to		 IEA
ISO		 (PMID:1374164) Ensembl
MGI		 PMID:1374164 GO_REF:0000107 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B enables ISO (PMID:12816890) MGI PMID:12816890 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A enables IEA Ensembl GO_REF:0000107 NCBI chr11:58,271,808...58,421,887
Ensembl chr11:58,273,377...58,421,761 		JBrowse link
G GRIN3B glutamate ionotropic receptor NMDA type subunit 3B contributes_to
enables		 ISO
IEA		 (MGI:3688366|PMID:14602821) UniProt
Ensembl		 PMID:14602821 GO_REF:0000107 MGI:3688366 NCBI chr20:57,703,569...57,710,119 JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 enables IEA UniProt GO_REF:0000043 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198 		JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 enables IEA UniProt GO_REF:0000043 NCBI chr27:20,806,670...21,278,638
Ensembl chr27:20,805,842...21,350,083 		JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 enables IEA UniProt GO_REF:0000043 NCBI chr12:2,970,613...3,050,254
Ensembl chr12:2,805,187...3,048,938 		JBrowse link
G LOC100687983 annexin A2-like enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:94,255,132...94,263,097 JBrowse link
G LOC119877460 polycystic kidney disease protein 1-like 1 enables IEA Ensembl GO_REF:0000107
G MCOLN1 mucolipin TRP cation channel 1 enables ISO (PMID:25720963), (PMID:29019983) UniProt PMID:25720963 PMID:29019983 NCBI chr20:52,318,411...52,327,389
Ensembl chr20:52,318,408...52,348,963 		JBrowse link
G MCU mitochondrial calcium uniporter enables IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:23,309,376...23,508,480
Ensembl chr 4:23,309,391...23,506,586 		JBrowse link
G MCUB mitochondrial calcium uniporter dominant negative subunit beta enables IEA UniProt GO_REF:0000043 GO_REF:0000104 NCBI chr32:29,793,439...29,890,060
Ensembl chr32:29,793,556...29,890,033 		JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 enables IEA Ensembl
UniProt		 GO_REF:0000043 GO_REF:0000107 NCBI chr26:7,584,276...7,599,667
Ensembl chr26:7,584,880...7,599,401 		JBrowse link
G PANX1 pannexin 1 enables IEA Ensembl GO_REF:0000107 NCBI chr21:6,665,730...6,715,272
Ensembl chr21:6,668,269...6,715,858 		JBrowse link
G PANX3 pannexin 3 enables ISO (MGI:5052205|PMID:21690309) UniProt PMID:21690309 MGI:5052205 NCBI chr 5:9,787,513...9,794,292
Ensembl chr 5:9,787,947...9,794,166 		JBrowse link
G PANX3 pannexin 3 enables IEA Ensembl GO_REF:0000107
G PKD1 polycystin 1, transient receptor potential channel interacting contributes_to
enables		 ISO (PMID:27214281)
(MGI:2449360|PMID:12514735)		 UniProt
BHF-UCL		 PMID:12514735 PMID:27214281 MGI:2449360 NCBI chr 6:38,811,051...38,865,503
Ensembl chr 6:38,837,964...38,865,503 		JBrowse link
G PKD1L1 polycystin 1 like 1, transient receptor potential channel interacting enables IEA Ensembl GO_REF:0000107 NCBI chr16:119,639...199,418 JBrowse link
G PKD1L3 polycystin 1 like 3, transient receptor potential channel interacting enables IEA TreeGrafter GO_REF:0000118 NCBI chr 5:77,690,991...77,756,355
Ensembl chr 5:77,692,200...77,754,474 		JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel contributes_to
enables		 ISO
IEA		 (PMID:27214281) UniProt
Ensembl
UniProt		 PMID:27214281 GO_REF:0000043 GO_REF:0000107 NCBI chr32:11,383,441...11,437,603
Ensembl chr32:11,383,424...11,435,438 		JBrowse link
G PKD2L1 polycystin 2 like 1, transient receptor potential cation channel enables IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr28:13,045,749...13,076,072
Ensembl chr28:13,045,829...13,076,485 		JBrowse link
G PKD2L2 polycystin 2 like 2, transient receptor potential cation channel enables IEA UniProt
TreeGrafter		 GO_REF:0000043 GO_REF:0000118 NCBI chr11:25,594,327...25,628,262
Ensembl chr11:25,594,394...25,628,509 		JBrowse link
G PKDREJ polycystin family receptor for egg jelly enables IEA TreeGrafter GO_REF:0000118 NCBI chr10:19,914,217...19,921,766
Ensembl chr10:19,914,721...19,920,822 		JBrowse link
G PKDREJ polycystin family receptor for egg jelly enables IEA TreeGrafter GO_REF:0000118
G PSEN1 presenilin 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532 		JBrowse link
G RYR1 ryanodine receptor 1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:114,461,350...114,579,577
Ensembl chr 1:114,461,348...114,579,493 		JBrowse link
G RYR2 ryanodine receptor 2 enables IEA UniProt GO_REF:0000043 NCBI chr 4:2,371,868...2,908,132
Ensembl chr 4:2,373,114...2,907,875 		JBrowse link
G RYR3 ryanodine receptor 3 enables IEA UniProt GO_REF:0000043 NCBI chr30:1,179,575...1,533,352
Ensembl chr30:1,180,359...1,533,619 		JBrowse link
G SEC61A1 SEC61 translocon subunit alpha 1 enables IEA Ensembl GO_REF:0000107 NCBI chr20:2,070,739...2,087,790
Ensembl chr20:2,070,248...2,087,789 		JBrowse link
G SLC24A1 solute carrier family 24 member 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr30:29,967,762...29,996,762
Ensembl chr30:29,967,762...29,995,005 		JBrowse link
G SLC24A2 solute carrier family 24 member 2 enables IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:39,273,285...39,521,223
Ensembl chr11:39,278,370...39,519,222 		JBrowse link
G SLC24A3 solute carrier family 24 member 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr24:3,593,562...4,014,366
Ensembl chr24:3,593,513...3,784,467 		JBrowse link
G SLC24A4 solute carrier family 24 member 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 8:1,570,833...1,685,135
Ensembl chr 8:1,517,560...1,680,208 		JBrowse link
G SLC24A5 solute carrier family 24 member 5 enables IEA TreeGrafter GO_REF:0000118 NCBI chr30:14,372,019...14,400,262
Ensembl chr30:14,371,778...14,400,152 		JBrowse link
G TMCO1 transmembrane and coiled-coil domains 1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr38:17,579,540...17,630,701
Ensembl chr38:17,579,607...17,630,283 		JBrowse link
G TMEM37 transmembrane protein 37 enables IEA InterPro GO_REF:0000002 NCBI chr19:30,579,207...30,585,308
Ensembl chr19:30,578,565...30,585,255 		JBrowse link
G TPCN2 two pore segment channel 2 enables IEA Ensembl GO_REF:0000107 NCBI chr18:48,956,833...48,984,499
Ensembl chr18:48,957,249...48,984,564 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr29:20,951,736...21,000,956
Ensembl chr29:20,951,716...21,001,208 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 enables IEA InterPro GO_REF:0000002 NCBI chr23:38,350,066...38,416,086
Ensembl chr23:38,350,278...38,414,464 		JBrowse link
G TRPC2 transient receptor potential cation channel subfamily C member 2 enables IEA InterPro GO_REF:0000002 NCBI chr21:26,163,641...26,202,938 JBrowse link
G TRPC3 transient receptor potential cation channel subfamily C member 3 enables IEA InterPro GO_REF:0000002 NCBI chr19:18,207,565...18,272,551
Ensembl chr19:18,207,417...18,271,828 		JBrowse link
G TRPC4 transient receptor potential cation channel subfamily C member 4 enables ISO
IEA		 RGD
InterPro		 PMID:11713258 GO_REF:0000002 RGD:625475 NCBI chr25:2,927,347...3,133,935
Ensembl chr25:2,981,518...3,132,829 		JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr  X:84,835,130...84,989,609
Ensembl chr  X:84,801,096...85,116,625 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 enables ISO
IEA		 RGD
InterPro		 PMID:20501650 GO_REF:0000002 RGD:7242941 NCBI chr 5:29,897,378...30,007,885
Ensembl chr 5:29,897,210...30,007,723 		JBrowse link
G TRPC7 transient receptor potential cation channel subfamily C member 7 enables IEA InterPro GO_REF:0000002 NCBI chr11:24,113,128...24,256,998
Ensembl chr11:24,113,932...24,252,989 		JBrowse link
G TRPM1 transient receptor potential cation channel subfamily M member 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:37,860,730...37,949,108
Ensembl chr 3:37,817,339...37,949,108 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 enables IEA UniProt GO_REF:0000043 NCBI chr31:38,201,075...38,224,076 JBrowse link
G TRPM3 transient receptor potential cation channel subfamily M member 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:86,525,054...87,023,561
Ensembl chr 1:86,242,487...87,017,292 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:107,261,760...107,304,157
Ensembl chr 1:107,261,756...107,303,346 		JBrowse link
G TRPM6 transient receptor potential cation channel subfamily M member 6 enables IEA UniProt GO_REF:0000043 NCBI chr 1:83,250,870...83,437,044
Ensembl chr 1:83,308,788...83,436,644 		JBrowse link
G TRPM7 transient receptor potential cation channel subfamily M member 7 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
UniProt		 PMID:12904301 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 RGD:1299260 NCBI chr30:16,465,546...16,579,874
Ensembl chr30:16,466,234...16,579,594 		JBrowse link
G TRPM8 transient receptor potential cation channel subfamily M member 8 enables IEA Ensembl GO_REF:0000107 NCBI chr25:45,261,092...45,357,560
Ensembl chr25:45,261,107...45,353,282 		JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 enables IEA Ensembl
TreeGrafter
UniProt		 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:47,404,987...47,443,871
Ensembl chr 9:47,404,972...47,431,926 		JBrowse link
G TRPV2 transient receptor potential cation channel subfamily V member 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:39,488,155...39,512,454
Ensembl chr 5:39,491,484...39,509,902 		JBrowse link
G TRPV3 transient receptor potential cation channel subfamily V member 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:47,365,275...47,398,198
Ensembl chr 9:47,368,544...47,401,362 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr26:17,293,334...17,330,156
Ensembl chr26:17,262,100...17,330,165 		JBrowse link
G TRPV5 transient receptor potential cation channel subfamily V member 5 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:19463684 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:7205490 NCBI chr16:6,647,070...6,678,080
Ensembl chr16:6,650,574...6,676,963 		JBrowse link
G TRPV6 transient receptor potential cation channel subfamily V member 6 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:10875938 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:632623 NCBI chr16:6,691,521...6,706,205
Ensembl chr16:6,691,254...6,706,207 		JBrowse link
calcium-induced calcium release activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BNIP1 BCL2 interacting protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:39,255,685...39,303,485
Ensembl chr 4:39,289,776...39,303,430 		JBrowse link
G FAM98C family with sequence similarity 98 member C enables IEA Ensembl GO_REF:0000107 NCBI chr 1:114,598,841...114,602,316
Ensembl chr 1:114,597,464...114,602,708 		JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel enables IEA Ensembl GO_REF:0000107 NCBI chr32:11,383,441...11,437,603
Ensembl chr32:11,383,424...11,435,438 		JBrowse link
G RYR1 ryanodine receptor 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 1:114,461,350...114,579,577
Ensembl chr 1:114,461,348...114,579,493 		JBrowse link
G RYR2 ryanodine receptor 2 enables ISO
IEA		 RGD
Ensembl		 PMID:18799678 GO_REF:0000107 RGD:7175259 NCBI chr 4:2,371,868...2,908,132
Ensembl chr 4:2,373,114...2,907,875 		JBrowse link
G RYR3 ryanodine receptor 3 ISO RGD PMID:18799678 RGD:7175259 NCBI chr30:1,179,575...1,533,352
Ensembl chr30:1,180,359...1,533,619 		JBrowse link
glutamate-gated calcium ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 enables ISO PMID:1709304
PMID:11773314		 UniProt PMID:1709304 PMID:11773314 RGD:401966868 RGD:401966871 NCBI chr 4:55,801,269...56,103,383
Ensembl chr 4:55,803,296...56,103,669 		JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 enables ISO PMID:11773314 UniProt PMID:11773314 RGD:401966871 NCBI chr15:54,634,332...54,710,711
Ensembl chr15:54,634,335...54,708,184 		JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 enables ISO PMID:1709304 UniProt PMID:1709304 RGD:401966868 NCBI chr  X:94,729,828...95,006,244
Ensembl chr  X:94,730,943...95,004,279 		JBrowse link
G GRIK1 glutamate ionotropic receptor kainate type subunit 1 enables ISO PMID:11425885
PMID:12873388		 UniProt PMID:11425885 PMID:12873388 RGD:405650374 RGD:405650399 NCBI chr31:24,477,319...24,839,502
Ensembl chr31:24,478,696...24,839,434 		JBrowse link
G GRIK2 glutamate ionotropic receptor kainate type subunit 2 enables ISO PMID:7681676 UniProt PMID:7681676 RGD:405650269 NCBI chr12:58,932,754...59,991,305
Ensembl chr12:59,355,017...59,990,408 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 enables ISO (PMID:26875626) UniProt PMID:26875626 NCBI chr 9:48,492,967...48,513,981
Ensembl chr 9:48,493,287...48,509,050 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A enables IEA Ensembl GO_REF:0000107 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B enables IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680 		JBrowse link
G GRIN2C glutamate ionotropic receptor NMDA type subunit 2C enables IEA Ensembl GO_REF:0000107 NCBI chr 9:5,582,404...5,595,540
Ensembl chr 9:5,576,681...5,595,146 		JBrowse link
G GRIN2D glutamate ionotropic receptor NMDA type subunit 2D enables IEA Ensembl GO_REF:0000107 NCBI chr 1:107,821,853...107,853,411
Ensembl chr 1:107,822,716...107,849,945 		JBrowse link
high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:17068255 PMID:21611731 GO_REF:0000107 GO_REF:0000118 RGD:7205477 RGD:7205480 NCBI chr20:48,747,087...49,036,627
Ensembl chr20:48,821,025...49,036,032 		JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B enables ISO
IEA		 RGD
TreeGrafter		 PMID:18701069 GO_REF:0000118 RGD:7205441 NCBI chr 9:47,813,625...48,009,532
Ensembl chr 9:47,816,393...48,009,406 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C enables ISO
IEA		 RGD
TreeGrafter		 PMID:17068255 GO_REF:0000118 RGD:7205477 NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D contributes_to
enables		 ISO
IEA		 (PMID:1309651) BHF-UCL
TreeGrafter
Ensembl
RGD		 PMID:1309651 PMID:18322004 GO_REF:0000107 GO_REF:0000118 RGD:7207845 NCBI chr20:36,189,986...36,488,460
Ensembl chr20:36,191,810...36,613,686 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E enables IEA TreeGrafter GO_REF:0000118 NCBI chr 7:14,892,165...15,267,418
Ensembl chr 7:14,707,801...15,267,422 		JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F enables IEA TreeGrafter GO_REF:0000118 NCBI chr  X:42,302,971...42,327,787
Ensembl chr  X:42,303,158...42,326,774 		JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:7479909 GO_REF:0000107 GO_REF:0000118 RGD:634679 NCBI chr 7:2,108,716...2,172,246
Ensembl chr 7:2,108,455...2,303,220 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 enables ISO (PMID:11756409) MGI PMID:11756409 NCBI chr 9:23,182,407...23,197,035
Ensembl chr 9:23,180,554...23,195,673 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to
enables		 ISO
IEA		 (PMID:1309651) BHF-UCL
Ensembl		 PMID:1309651 GO_REF:0000107 NCBI chr 2:18,537,100...18,787,728
Ensembl chr 2:18,538,620...18,902,286 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 contributes_to ISO PMID:25527503 BHF-UCL PMID:25527503 RGD:11059598 NCBI chr27:5,705,587...5,714,620
Ensembl chr27:5,706,064...5,717,647 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 contributes_to
enables		 ISO
IEA		 (PMID:11880487) UniProtKB
Ensembl		 PMID:11880487 GO_REF:0000107 NCBI chr19:52,987,170...53,116,410
Ensembl chr19:52,993,618...53,116,140
Ensembl chr19:52,993,618...53,116,140 		JBrowse link
inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 enables IEA Ensembl GO_REF:0000107 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198 		JBrowse link
inositol 1,4,5-trisphosphate-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro
UniProt		 PMID:15533917 PMID:19036964 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:6480876 RGD:7175271 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198 		JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
UniProt
InterPro		 PMID:10969001 PMID:15533917 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 RGD:7175271 RGD:7175277 NCBI chr27:20,806,670...21,278,638
Ensembl chr27:20,805,842...21,350,083 		JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 enables ISO
IEA		 RGD
Ensembl
UniProt
InterPro		 PMID:10694253 PMID:15533917 PMID:17320950 PMID:17373911 GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 RGD:2290285 RGD:7175265 RGD:7175268 RGD:7175271 NCBI chr12:2,970,613...3,050,254
Ensembl chr12:2,805,187...3,048,938 		JBrowse link
intracellularly gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 enables IEA Ensembl GO_REF:0000107 NCBI chr20:12,746,171...13,065,256
Ensembl chr20:12,747,315...13,064,198 		JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 enables IEA Ensembl GO_REF:0000107 NCBI chr27:20,806,670...21,278,638
Ensembl chr27:20,805,842...21,350,083 		JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 enables IEA Ensembl GO_REF:0000107 NCBI chr12:2,970,613...3,050,254
Ensembl chr12:2,805,187...3,048,938 		JBrowse link
G RASA3 RAS p21 protein activator 3 enables IEA Ensembl GO_REF:0000107 NCBI chr22:61,093,762...61,202,209
Ensembl chr22:61,095,044...61,202,152 		JBrowse link
G RYR2 ryanodine receptor 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:2,371,868...2,908,132
Ensembl chr 4:2,373,114...2,907,875 		JBrowse link
G RYR3 ryanodine receptor 3 enables IEA Ensembl GO_REF:0000107 NCBI chr30:1,179,575...1,533,352
Ensembl chr30:1,180,359...1,533,619 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 enables IEA Ensembl GO_REF:0000107 NCBI chr29:20,951,736...21,000,956
Ensembl chr29:20,951,716...21,001,208 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 enables IEA Ensembl GO_REF:0000107 NCBI chr31:38,201,075...38,224,076 JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 enables ISS UniProt GO_REF:0000024 NCBI chr 9:47,404,987...47,443,871
Ensembl chr 9:47,404,972...47,431,926 		JBrowse link
ligand-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MCOLN1 mucolipin TRP cation channel 1 enables IEA Ensembl GO_REF:0000107 NCBI chr20:52,318,411...52,327,389
Ensembl chr20:52,318,408...52,348,963 		JBrowse link
G P2RX1 purinergic receptor P2X 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:47,674,175...47,694,358
Ensembl chr 9:47,675,300...47,688,858 		JBrowse link
G P2RX4 purinergic receptor P2X 4 enables IEA Ensembl GO_REF:0000107 NCBI chr26:7,897,528...7,914,279
Ensembl chr26:7,898,015...7,914,234 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr31:38,201,075...38,224,076 JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:107,261,760...107,304,157
Ensembl chr 1:107,261,756...107,303,346 		JBrowse link
G TRPM5 transient receptor potential cation channel subfamily M member 5 enables IEA TreeGrafter GO_REF:0000118 NCBI chr18:46,479,397...46,493,279
Ensembl chr18:46,478,759...46,498,043 		JBrowse link
G TRPM8 transient receptor potential cation channel subfamily M member 8 enables IEA TreeGrafter GO_REF:0000118 NCBI chr25:45,261,092...45,357,560
Ensembl chr25:45,261,107...45,353,282 		JBrowse link
low voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1G calcium voltage-gated channel subunit alpha1 G enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:16935432 PMID:18759855 PMID:18760992 GO_REF:0000107 GO_REF:0000118 RGD:2308879 RGD:7175320 RGD:7207257 NCBI chr 9:26,481,148...26,544,511
Ensembl chr 9:26,481,652...26,544,845 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:11073957 PMID:16935432 GO_REF:0000107 GO_REF:0000118 RGD:68748 RGD:7207257 NCBI chr 6:39,510,129...39,533,129
Ensembl chr 6:39,510,121...39,533,753 		JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I enables ISO
IEA		 RGD
TreeGrafter		 PMID:16935432 PMID:18760992 GO_REF:0000118 RGD:7175320 RGD:7207257 NCBI chr10:25,381,446...25,493,680
Ensembl chr10:25,380,943...25,482,852 		JBrowse link
NAADP-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MCOLN1 mucolipin TRP cation channel 1 enables ISO
IEA		 RGD
TreeGrafter		 PMID:17613490 GO_REF:0000118 RGD:7205504 NCBI chr20:52,318,411...52,327,389
Ensembl chr20:52,318,408...52,348,963 		JBrowse link
G MCOLN2 mucolipin TRP cation channel 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:62,956,797...63,008,527
Ensembl chr 6:62,956,804...63,200,612 		JBrowse link
G MCOLN3 mucolipin TRP cation channel 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:62,923,598...62,953,696
Ensembl chr 6:62,923,267...62,953,564 		JBrowse link
G TPCN1 two pore segment channel 1 NOT|enables ISO
IEA		 (PMID:24776928)
(MGI:6718238|PMID:24776928)		 UniProt
Ensembl		 PMID:24776928 GO_REF:0000107 MGI:6718238 NCBI chr26:10,599,898...10,662,269
Ensembl chr26:10,599,780...10,660,767 		JBrowse link
G TPCN2 two pore segment channel 2 NOT|enables ISO
IEA		 (PMID:23063126) UniProt
Ensembl		 PMID:23063126 GO_REF:0000107 NCBI chr18:48,956,833...48,984,499
Ensembl chr18:48,957,249...48,984,564 		JBrowse link
ryanodine-sensitive calcium-release channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAM98C family with sequence similarity 98 member C enables IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:114,598,841...114,602,316
Ensembl chr 1:114,597,464...114,602,708 		JBrowse link
G RYR1 ryanodine receptor 1 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:19230144 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:7175256 NCBI chr 1:114,461,350...114,579,577
Ensembl chr 1:114,461,348...114,579,493 		JBrowse link
G RYR2 ryanodine receptor 2 enables ISO
IEA		 RGD
TreeGrafter
Ensembl
InterPro		 PMID:18799678 PMID:21807619 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:7175254 RGD:7175259 NCBI chr 4:2,371,868...2,908,132
Ensembl chr 4:2,373,114...2,907,875 		JBrowse link
G RYR3 ryanodine receptor 3 enables ISO
IEA		 RGD
TreeGrafter
InterPro		 PMID:18799678 GO_REF:0000002 GO_REF:0000118 RGD:7175259 NCBI chr30:1,179,575...1,533,352
Ensembl chr30:1,180,359...1,533,619 		JBrowse link
store-operated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ORAI1 ORAI calcium release-activated calcium modulator 1 enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:21389210 GO_REF:0000107 GO_REF:0000118 RGD:7175077 NCBI chr26:7,584,276...7,599,667
Ensembl chr26:7,584,880...7,599,401 		JBrowse link
G ORAI2 ORAI calcium release-activated calcium modulator 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:7,725,901...7,738,477
Ensembl chr 6:7,728,505...7,737,962 		JBrowse link
G ORAI3 ORAI calcium release-activated calcium modulator 3 enables IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:17,248,900...17,253,935
Ensembl chr 6:17,248,884...17,274,850 		JBrowse link
G STIM1 stromal interaction molecule 1 ISO RGD PMID:21389210 RGD:7175077 NCBI chr21:26,394,592...26,594,764
Ensembl chr21:26,394,811...26,593,375 		JBrowse link
G STIM2 stromal interaction molecule 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 3:83,560,690...83,703,978
Ensembl chr 3:83,564,108...83,724,520 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr23:38,350,066...38,416,086
Ensembl chr23:38,350,278...38,414,464 		JBrowse link
G TRPC2 transient receptor potential cation channel subfamily C member 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr21:26,163,641...26,202,938 JBrowse link
G TRPC3 transient receptor potential cation channel subfamily C member 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr19:18,207,565...18,272,551
Ensembl chr19:18,207,417...18,271,828 		JBrowse link
G TRPC4 transient receptor potential cation channel subfamily C member 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr25:2,927,347...3,133,935
Ensembl chr25:2,981,518...3,132,829 		JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 enables IEA TreeGrafter GO_REF:0000118 NCBI chr  X:84,835,130...84,989,609
Ensembl chr  X:84,801,096...85,116,625 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 5:29,897,378...30,007,885
Ensembl chr 5:29,897,210...30,007,723 		JBrowse link
G TRPC7 transient receptor potential cation channel subfamily C member 7 enables IEA TreeGrafter GO_REF:0000118 NCBI chr11:24,113,128...24,256,998
Ensembl chr11:24,113,932...24,252,989 		JBrowse link
stretch-activated, monoatomic cation-selective, calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NALF1 NALCN channel auxiliary factor 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr22:56,134,925...56,757,072
Ensembl chr22:56,134,878...56,756,612 		JBrowse link
G NALF2 NALCN channel auxiliary factor 2 enables IEA TreeGrafter GO_REF:0000118 NCBI chr  X:53,969,675...53,998,274
Ensembl chr  X:53,969,665...53,997,140 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 enables IEA Ensembl GO_REF:0000107 NCBI chr26:17,293,334...17,330,156
Ensembl chr26:17,262,100...17,330,165 		JBrowse link
voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACHD1 cache domain containing 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 5:45,554,740...45,676,324
Ensembl chr 5:45,556,477...45,676,655 		JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A enables ISO
IEA		 RGD
Ensembl
InterPro		 PMID:9593738 PMID:16049183 GO_REF:0000002 GO_REF:0000107 RGD:1582495 RGD:634678 NCBI chr20:48,747,087...49,036,627
Ensembl chr20:48,821,025...49,036,032 		JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B enables ISO
IEA		 RGD
InterPro		 PMID:10864934 GO_REF:0000002 RGD:1299351 NCBI chr 9:47,813,625...48,009,532
Ensembl chr 9:47,816,393...48,009,406 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C enables ISO
IEA		 RGD
UniProt
InterPro		 PMID:16483597 PMID:16554304 GO_REF:0000002 GO_REF:0000117 RGD:1580158 RGD:1582591 NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D enables ISO
IEA		 RGD
Ensembl
UniProt
InterPro		 PMID:11487617 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 RGD:727563 NCBI chr20:36,189,986...36,488,460
Ensembl chr20:36,191,810...36,613,686 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E enables ISO
IEA		 RGD
Ensembl
InterPro		 PMID:21611731 GO_REF:0000002 GO_REF:0000107 RGD:7205480 NCBI chr 7:14,892,165...15,267,418
Ensembl chr 7:14,707,801...15,267,422 		JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr  X:42,302,971...42,327,787
Ensembl chr  X:42,303,158...42,326,774 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 9:26,481,148...26,544,511
Ensembl chr 9:26,481,652...26,544,845 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H enables IEA InterPro GO_REF:0000002 NCBI chr 6:39,510,129...39,533,129
Ensembl chr 6:39,510,121...39,533,753 		JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I enables IEA InterPro GO_REF:0000002 NCBI chr10:25,381,446...25,493,680
Ensembl chr10:25,380,943...25,482,852 		JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr 7:2,108,716...2,172,246
Ensembl chr 7:2,108,455...2,303,220 		JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 contributes_to
enables		 ISO
IEA		 (PMID:11160515), (PMID:17224476) UniProtKB
TreeGrafter
Ensembl
RGD		 PMID:11160515 PMID:11604404 PMID:17224476 GO_REF:0000107 GO_REF:0000118 RGD:625474 NCBI chr18:21,561,091...21,949,970
Ensembl chr18:21,564,676...21,949,544 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:12606261 GO_REF:0000107 GO_REF:0000118 RGD:632381 NCBI chr20:38,859,047...38,995,239
Ensembl chr20:38,883,530...38,993,273 		JBrowse link
G CACNA2D3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 enables ISO
IEA		 RGD
TreeGrafter		 PMID:12606261 GO_REF:0000118 RGD:632381 NCBI chr20:35,097,185...36,043,562
Ensembl chr20:35,097,182...35,956,774 		JBrowse link
G CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr27:43,840,190...43,961,067
Ensembl chr27:43,844,529...44,041,637 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 contributes_to
enables		 ISO
IEA		 RGD
Ensembl
InterPro		 PMID:16049183 PMID:16554304 GO_REF:0000002 GO_REF:0000107 RGD:1582495 RGD:1582591 NCBI chr 9:23,182,407...23,197,035
Ensembl chr 9:23,180,554...23,195,673 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to
enables		 ISO
IEA		 RGD
Ensembl
InterPro		 PMID:16049183 GO_REF:0000002 GO_REF:0000107 RGD:1582495 NCBI chr 2:18,537,100...18,787,728
Ensembl chr 2:18,538,620...18,902,286 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 contributes_to
enables		 ISO
IEA		 (PMID:11160515) UniProtKB
Ensembl
InterPro
RGD		 PMID:11160515 PMID:14559910 GO_REF:0000002 GO_REF:0000107 RGD:1358466 NCBI chr27:5,705,587...5,714,620
Ensembl chr27:5,706,064...5,717,647 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 enables
contributes_to		 ISO
IEA		 (PMID:16525042) RGD
Ensembl
InterPro
UniProtKB		 PMID:12821675 PMID:16525042 GO_REF:0000002 GO_REF:0000107 RGD:737839 NCBI chr19:52,987,170...53,116,410
Ensembl chr19:52,993,618...53,116,140
Ensembl chr19:52,993,618...53,116,140 		JBrowse link
G CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 9:13,425,898...13,438,275
Ensembl chr 9:13,426,105...13,438,614 		JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 enables IEA InterPro
TreeGrafter
Ensembl		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr10:27,750,314...27,862,646
Ensembl chr10:27,750,935...27,862,885 		JBrowse link
G CACNG3 calcium voltage-gated channel auxiliary subunit gamma 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:21,626,977...21,712,331
Ensembl chr 6:21,627,547...21,711,635 		JBrowse link
G CACNG4 calcium voltage-gated channel auxiliary subunit gamma 4 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:13,449,465...13,464,296
Ensembl chr 9:13,449,450...13,462,645 		JBrowse link
G CACNG5 calcium voltage-gated channel auxiliary subunit gamma 5 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:13,575,902...13,587,818
Ensembl chr 9:13,578,805...13,615,233 		JBrowse link
G CACNG7 calcium voltage-gated channel auxiliary subunit gamma 7 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:103,276,743...103,293,393
Ensembl chr 1:103,277,662...103,293,995 		JBrowse link
G CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:103,245,102...103,263,154
Ensembl chr 1:103,250,132...103,263,178 		JBrowse link
G CALHM1 calcium homeostasis modulator 1 enables IEA Ensembl GO_REF:0000107 NCBI chr28:15,821,121...15,826,029
Ensembl chr28:15,814,429...15,825,924 		JBrowse link
G CATSPER1 cation channel sperm associated 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr18:51,249,897...51,260,211
Ensembl chr18:51,250,039...51,260,168 		JBrowse link
G CATSPER2 cation channel sperm associated 2 enables ISO (PMID:21412338) UniProt PMID:21412338 NCBI chr30:10,471,798...10,487,948
Ensembl chr30:10,471,814...10,487,739 		JBrowse link
G CATSPER3 cation channel sperm associated 3 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:23,018,770...23,057,945
Ensembl chr11:23,021,663...23,052,820 		JBrowse link
G CATSPER4 cation channel sperm associated 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:73,789,706...73,804,463
Ensembl chr 2:73,789,707...73,804,373 		JBrowse link
G GRM7 glutamate metabotropic receptor 7 enables ISO (MGI:3690146|PMID:12065412) UniProt PMID:12065412 MGI:3690146 NCBI chr20:10,230,568...11,058,693
Ensembl chr20:10,230,557...11,058,703 		JBrowse link
G ITGAV integrin subunit alpha V enables IEA Ensembl GO_REF:0000107 NCBI chr36:28,815,215...28,890,569
Ensembl chr36:28,804,013...28,887,430 		JBrowse link
G NCS1 neuronal calcium sensor 1 enables ISO PMID:17502602 UniProt PMID:17502602 RGD:8553610 NCBI chr 9:53,661,361...53,676,925
Ensembl chr 9:53,672,910...53,676,910 		JBrowse link
G OPRM1 opioid receptor mu 1 enables ISO PMID:1846076 UniProt PMID:1846076 RGD:8656003 NCBI chr 1:43,972,915...44,037,477
Ensembl chr 1:43,972,219...44,141,238 		JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr32:11,383,441...11,437,603
Ensembl chr32:11,383,424...11,435,438 		JBrowse link
G RYR1 ryanodine receptor 1 enables ISO (MGI:3764002|PMID:18003898), (PMID:12954602) UniProt PMID:12954602 PMID:18003898 MGI:3764002 NCBI chr 1:114,461,350...114,579,577
Ensembl chr 1:114,461,348...114,579,493 		JBrowse link
G TMC1 transmembrane channel like 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:85,041,039...85,159,607
Ensembl chr 1:85,041,574...85,187,369 		JBrowse link
G TMC2 transmembrane channel like 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr24:18,576,966...18,642,204
Ensembl chr24:18,578,138...18,642,198 		JBrowse link
G TPCN2 two pore segment channel 2 NOT|enables ISO
IEA		 (PMID:23063126) UniProt
Ensembl		 PMID:23063126 GO_REF:0000107 NCBI chr18:48,956,833...48,984,499
Ensembl chr18:48,957,249...48,984,564 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 ISO RGD PMID:14712238 RGD:1303969 NCBI chr29:20,951,736...21,000,956
Ensembl chr29:20,951,716...21,001,208 		JBrowse link
voltage-gated calcium channel activity involved in AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C enables ISO (PMID:26253506) BHF-UCL PMID:26253506 NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G enables ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr 9:26,481,148...26,544,511
Ensembl chr 9:26,481,652...26,544,845 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to
enables		 ISO
IEA		 (PMID:17224476) BHF-UCL
Ensembl		 PMID:17224476 GO_REF:0000107 NCBI chr 2:18,537,100...18,787,728
Ensembl chr 2:18,538,620...18,902,286 		JBrowse link
voltage-gated calcium channel activity involved in bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 contributes_to
enables		 ISO
IEA		 (PMID:21383000) BHF-UCL
Ensembl		 PMID:21383000 GO_REF:0000107 NCBI chr18:21,561,091...21,949,970
Ensembl chr18:21,564,676...21,949,544 		JBrowse link
voltage-gated calcium channel activity involved in cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C contributes_to
enables		 ISO (PMID:17224476)
(PMID:32109384)
(PMID:15454078)		 BHF-UCL
MGI		 PMID:15454078 PMID:17224476 PMID:32109384 NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to
enables		 ISO
IEA		 (PMID:17224476) BHF-UCL
Ensembl		 PMID:17224476 GO_REF:0000107 NCBI chr 2:18,537,100...18,787,728
Ensembl chr 2:18,538,620...18,902,286 		JBrowse link
voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A enables ISO (PMID:25741235) SynGO PMID:25741235 NCBI chr20:48,747,087...49,036,627
Ensembl chr20:48,821,025...49,036,032 		JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B enables ISO PMID:7832825 SynGO PMID:7832825 RGD:13792530 NCBI chr 9:47,813,625...48,009,532
Ensembl chr 9:47,816,393...48,009,406 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D enables ISO (PMID:10929716) SynGO PMID:10929716 NCBI chr20:36,189,986...36,488,460
Ensembl chr20:36,191,810...36,613,686 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E enables ISO PMID:19193890 SynGO PMID:19193890 RGD:13792544 NCBI chr 7:14,892,165...15,267,418
Ensembl chr 7:14,707,801...15,267,422 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 2:18,537,100...18,787,728
Ensembl chr 2:18,538,620...18,902,286 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 enables IEA Ensembl GO_REF:0000107 NCBI chr19:52,987,170...53,116,410
Ensembl chr19:52,993,618...53,116,140
Ensembl chr19:52,993,618...53,116,140 		JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B enables ISO PMID:17067296 SynGO PMID:17067296 RGD:13702319 NCBI chr12:38,659,088...38,659,546 JBrowse link
G RIMBP2 RIMS binding protein 2 enables ISO (PMID:26402606) SynGO PMID:26402606 NCBI chr26:1,519,489...1,744,011
Ensembl chr26:1,645,591...1,744,020 		JBrowse link
G TSPOAP1 TSPO associated protein 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:32,949,912...32,972,830
Ensembl chr 9:32,950,906...32,973,982 		JBrowse link
voltage-gated calcium channel activity involved SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1D calcium voltage-gated channel subunit alpha1 D enables IEA Ensembl GO_REF:0000107 NCBI chr20:36,189,986...36,488,460
Ensembl chr20:36,191,810...36,613,686 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G enables ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr 9:26,481,148...26,544,511
Ensembl chr 9:26,481,652...26,544,845 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18798
    transporter activity 1259
      transmembrane transporter activity 1169
        monoatomic ion transmembrane transporter activity 768
          monoatomic ion channel activity 468
            monoatomic cation channel activity 360
              calcium channel activity 128
                ligand-gated calcium channel activity + 33
                store-operated calcium channel activity 12
                stretch-activated, monoatomic cation-selective, calcium channel activity + 3
                voltage-gated calcium channel activity + 44
Path 2
Term Annotations click to browse term
  molecular_function 18798
    transporter activity 1259
      transmembrane transporter activity 1169
        monoatomic ion transmembrane transporter activity 768
          monoatomic cation transmembrane transporter activity 645
            metal ion transmembrane transporter activity 451
              calcium ion transmembrane transporter activity 148
                calcium channel activity 128
                  ligand-gated calcium channel activity + 33
                  store-operated calcium channel activity 12
                  stretch-activated, monoatomic cation-selective, calcium channel activity + 3
                  voltage-gated calcium channel activity + 44
paths to the root