CACNA1I (calcium voltage-gated channel subunit alpha1 I) - Rat Genome Database

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Gene: CACNA1I (calcium voltage-gated channel subunit alpha1 I) Canis lupus familiaris
Analyze
Symbol: CACNA1I
Name: calcium voltage-gated channel subunit alpha1 I
RGD ID: 12314218
Description: ENCODES a protein that exhibits low voltage-gated calcium channel activity (ortholog); INVOLVED IN calcium ion import (ortholog); calcium ion transport (ortholog); calcium ion transport into cytosol (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); Developmental Disabilities (ortholog); hydrocephalus (ortholog); FOUND IN membrane (inferred); monoatomic ion channel complex (inferred); voltage-gated calcium channel complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ca(v)3.3; voltage-dependent T-type calcium channel subunit alpha-1I
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11025,381,446 - 25,493,680 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1025,380,943 - 25,482,852 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1025,317,909 - 25,429,936 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01026,133,456 - 26,245,748 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1026,134,925 - 26,234,803 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11025,845,366 - 25,946,629 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01026,167,842 - 26,279,957 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01026,337,549 - 26,455,352 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:17218348   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CACNA1I
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11025,381,446 - 25,493,680 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1025,380,943 - 25,482,852 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1025,317,909 - 25,429,936 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01026,133,456 - 26,245,748 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1026,134,925 - 26,234,803 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11025,845,366 - 25,946,629 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01026,167,842 - 26,279,957 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01026,337,549 - 26,455,352 (-)NCBIUU_Cfam_GSD_1.0
CACNA1I
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382239,570,753 - 39,689,735 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2239,570,753 - 39,689,735 (+)EnsemblGRCh38hg38GRCh38
GRCh372239,966,758 - 40,085,740 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362238,296,704 - 38,415,686 (+)NCBINCBI36Build 36hg18NCBI36
Build 342238,291,257 - 38,410,238NCBI
Celera2223,768,830 - 23,887,794 (+)NCBICelera
Cytogenetic Map22q13.1NCBI
HuRef2222,931,166 - 23,048,848 (+)NCBIHuRef
CHM1_12239,925,499 - 40,044,841 (+)NCBICHM1_1
T2T-CHM13v2.02240,041,540 - 40,160,675 (+)NCBIT2T-CHM13v2.0
Cacna1i
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391580,171,439 - 80,282,493 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1580,171,439 - 80,282,480 (+)EnsemblGRCm39 Ensembl
GRCm381580,287,238 - 80,398,292 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1580,287,238 - 80,398,279 (+)EnsemblGRCm38mm10GRCm38
MGSCv371580,117,668 - 80,228,722 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361580,114,300 - 80,225,547 (+)NCBIMGSCv36mm8
Celera1582,404,367 - 82,516,148 (+)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.85NCBI
Cacna1i
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87113,716,266 - 113,827,670 (+)NCBIGRCr8
mRatBN7.27111,835,996 - 111,947,418 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7111,836,012 - 111,944,688 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7113,591,130 - 113,702,387 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07115,814,660 - 115,925,924 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07115,784,029 - 115,895,287 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07121,521,787 - 121,619,300 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7121,511,097 - 121,619,283 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07121,509,362 - 121,609,542 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47118,582,279 - 118,681,537 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17118,604,777 - 118,715,750 (+)NCBI
Celera7108,173,442 - 108,270,677 (+)NCBICelera
Cytogenetic Map7q34NCBI
Cacna1i
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541325,453,703 - 25,535,530 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541325,440,533 - 25,538,367 (+)NCBIChiLan1.0ChiLan1.0
CACNA1I
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22349,404,522 - 49,536,330 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12252,095,860 - 52,227,638 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02220,463,511 - 20,595,253 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12238,325,411 - 38,412,923 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2238,296,436 - 38,414,963 (+)Ensemblpanpan1.1panPan2
Cacna1i
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049458,980,016 - 9,035,382 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364921,998,793 - 2,075,257 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364921,990,430 - 2,030,744 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CACNA1I
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl58,595,909 - 8,701,367 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.158,593,014 - 8,702,734 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.255,894,595 - 6,011,363 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CACNA1I
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11922,129,795 - 22,264,485 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1922,143,980 - 22,261,098 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045103,346,665 - 103,503,501 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cacna1i
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247528,705,149 - 8,785,272 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247528,702,320 - 8,795,192 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CACNA1I
1399 total Variants

Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
6 5 5 23 22 16 6 6 6 6 33 22 12 14 10

Sequence


Ensembl Acc Id: ENSCAFT00000002048   ⟹   ENSCAFP00000001896
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1025,380,943 - 25,482,852 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000046802   ⟹   ENSCAFP00000037060
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1025,380,943 - 25,482,852 (-)Ensembl
Ensembl Acc Id: ENSCAFT00000059550   ⟹   ENSCAFP00000059484
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1025,380,943 - 25,482,852 (-)Ensembl
Ensembl Acc Id: ENSCAFT00845037623   ⟹   ENSCAFP00845029479
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1026,134,925 - 26,234,803 (-)Ensembl
RefSeq Acc Id: XM_038489579   ⟹   XP_038345507
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11025,845,366 - 25,946,629 (-)NCBI
RefSeq Acc Id: XM_038551567   ⟹   XP_038407495
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01026,337,549 - 26,455,352 (-)NCBI
RefSeq Acc Id: XM_038613515   ⟹   XP_038469443
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01026,167,842 - 26,279,957 (-)NCBI
RefSeq Acc Id: XM_038640716   ⟹   XP_038496644
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1025,317,909 - 25,429,936 (-)NCBI
RefSeq Acc Id: XM_038678882   ⟹   XP_038534810
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01026,133,456 - 26,245,748 (-)NCBI
Ensembl Acc Id: ENSCAFP00000059484   ⟸   ENSCAFT00000059550
Ensembl Acc Id: ENSCAFP00000001896   ⟸   ENSCAFT00000002048
Ensembl Acc Id: ENSCAFP00000037060   ⟸   ENSCAFT00000046802
RefSeq Acc Id: XP_038345507   ⟸   XM_038489579
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038469443   ⟸   XM_038613515
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038534810   ⟸   XM_038678882
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JPA9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038496644   ⟸   XM_038640716
- Peptide Label: isoform X1
- UniProtKB: A0A8C0JPA9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407495   ⟸   XM_038551567
- Peptide Label: isoform X3
- UniProtKB: A0A8C0JPA9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCAFP00845029479   ⟸   ENSCAFT00845037623
Protein Domains
Ion transport


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001314 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018072 UniProtKB/TrEMBL
  ENSCAFG00845021242 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000046802.4 UniProtKB/TrEMBL
  ENSCAFT00030033689.1 UniProtKB/TrEMBL
  ENSCAFT00845037623 ENTREZGENE
  ENSCAFT00845037623.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  VDCC_T_a1 UniProtKB/TrEMBL
  VDCCAlpha1 UniProtKB/TrEMBL
  VGCC_Ca_Na UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
NCBI Gene CACNA1I ENTREZGENE
PANTHER PTHR10037 UniProtKB/TrEMBL
  PTHR10037:SF209 UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/TrEMBL
PRINTS CACHANNEL UniProtKB/TrEMBL
  TVDCCALPHA1 UniProtKB/TrEMBL
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A8C0JPA9 ENTREZGENE
  A0A8C0NPE1_CANLF UniProtKB/TrEMBL
  A0A8I3PMQ9_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:38639 ENTREZGENE