SLC24A3 (solute carrier family 24 member 3)

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Gene: SLC24A3 (solute carrier family 24 member 3) Canis lupus familiaris

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Symbol:

SLC24A3

Name:

solute carrier family 24 member 3

RGD ID:

12070621

Description:

ENCODES a protein that exhibits calcium, potassium:sodium antiporter activity (ortholog); INVOLVED IN bone mineralization (ortholog); intracellular calcium ion homeostasis (ortholog); monoatomic cation transport (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); familial hyperinsulinemic hypoglycemia 1 (ortholog); Salivary Gland Neoplasms (ortholog); FOUND IN cell periphery (inferred); membrane (inferred); plasma membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

sodium/potassium/calcium exchanger 3

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	3,593,562 - 4,014,366 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	3,593,513 - 3,784,467 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	3,620,103 - 3,818,880 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	4,000,491 - 4,482,100 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	4,000,493 - 4,482,430 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	3,595,752 - 4,077,406 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	3,699,250 - 4,181,348 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	3,977,410 - 4,458,938 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

adenoid cystic carcinoma (ISO)

familial hyperinsulinemic hypoglycemia 1 (ISO)

Salivary Gland Neoplasms (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bone mineralization (IEA,ISO)

calcium ion transmembrane transport (IEA)

calcium ion transport (IEA)

intracellular calcium ion homeostasis (IEA,ISO)

monoatomic cation transport (ISO)

negative regulation of gene expression (IEA,ISO)

positive regulation of gene expression (IEA,ISO)

potassium ion transmembrane transport (IEA)

sodium ion transmembrane transport (IEA)

transmembrane transport (IEA)

Cellular Component

cell periphery (IEA)

membrane (IEA)

plasma membrane (IEA)

Molecular Function

antiporter activity (IEA)

calcium, potassium:sodium antiporter activity (IEA,ISO)

symporter activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium transport pathway (ISO)

calcium/calcium-mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SLC24A3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	3,593,562 - 4,014,366 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	3,593,513 - 3,784,467 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	3,620,103 - 3,818,880 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	4,000,491 - 4,482,100 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	4,000,493 - 4,482,430 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	3,595,752 - 4,077,406 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	3,699,250 - 4,181,348 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	3,977,410 - 4,458,938 (-)	NCBI		UU_Cfam_GSD_1.0

SLC24A3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	19,212,642 - 19,722,926 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	19,212,642 - 19,722,926 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	19,193,286 - 19,703,570 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	19,141,290 - 19,651,541 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	19,141,289 - 19,651,540	NCBI
Celera	20	19,267,475 - 19,777,636 (+)	NCBI		Celera
Cytogenetic Map	20	p11.23	NCBI
HuRef	20	19,155,790 - 19,666,236 (+)	NCBI		HuRef
CHM1_1	20	19,262,244 - 19,704,077 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	19,264,159 - 19,774,968 (+)	NCBI		T2T-CHM13v2.0

Slc24a3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	145,009,695 - 145,484,086 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	145,009,674 - 145,484,086 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	145,167,775 - 145,642,166 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	145,167,754 - 145,642,166 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	145,068,347 - 145,467,689 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	144,934,052 - 145,333,394 (+)	NCBI		MGSCv36	mm8
Celera	2	146,442,567 - 146,852,275 (+)	NCBI		Celera
Cytogenetic Map	2	G1	NCBI
cM Map	2	71.08	NCBI

Slc24a3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	153,005,418 - 153,504,497 (+)	NCBI		GRCr8
mRatBN7.2	3	132,552,119 - 133,051,192 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	132,551,595 - 133,051,192 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	136,458,426 - 136,960,748 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	145,042,522 - 145,544,835 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	142,745,677 - 143,247,999 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	139,333,942 - 139,835,728 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	139,695,028 - 139,833,967 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	145,760,074 - 146,259,491 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	133,734,890 - 134,249,326 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	133,640,575 - 134,153,200 (+)	NCBI
Celera	3	131,419,773 - 131,916,131 (+)	NCBI		Celera
Cytogenetic Map	3	q41	NCBI

Slc24a3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	27,477,819 - 27,928,383 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	27,477,801 - 27,930,108 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC24A3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	20,097,895 - 20,610,669 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	20,094,738 - 20,607,505 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	19,168,820 - 19,680,706 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	19,137,943 - 19,648,235 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	19,137,938 - 19,646,475 (+)	Ensembl	panpan1.1		panPan2

Slc24a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	152,206,337 - 152,654,468 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936485	639,532 - 1,085,830 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936485	637,715 - 1,085,860 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC24A3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	27,270,093 - 27,780,526 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	27,270,232 - 27,780,535 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	31,405,580 - 31,468,072 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC24A3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	48,238,872 - 48,736,517 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666078	3,017,793 - 3,516,931 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc24a3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	19,808,255 - 20,297,056 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624741	19,808,186 - 20,298,772 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SLC24A3
3819 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005634727	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022409292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022409293	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432993	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038432996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038457556	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038508206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038508207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038508208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038508209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038571460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038571461	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038571462	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038571463	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038635699	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038635700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038635701	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038635702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000008649 ⟹ ENSCAFP00000008016

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	24	3,593,513 - 3,784,467 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00000045725 ⟹ ENSCAFP00000038552

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	24	3,593,513 - 3,722,860 (-)	Ensembl

Ensembl Acc Id:

ENSCAFT00845051965 ⟹ ENSCAFP00845040770

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	24	4,000,493 - 4,482,430 (-)	Ensembl

RefSeq Acc Id:

XM_022409292 ⟹ XP_022265000

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	24	3,593,562 - 3,790,696 (-)	NCBI
Dog10K_Boxer_Tasha	24	3,620,103 - 3,818,880 (-)	NCBI

Sequence:

show sequence

GAGAGCATAGGTCTACAGATGCCATGAATGTCCCTGATACATTCTTTTCTCCAAATGAAAGAGA
AAATACTCTCCATCCCTTGCAAACCTCCATTTGGACTCATCAAACTCAGGCCTCAGGAAAGCAG
CCAGGAGAAGCAGGACAGCTGACTGCTGTTGCCTTGGTAAGGGGAATCTACTCCCTTCAGGGCT
CTGTGGTTTCTATGGGAACAGCACTGCTTGCCTTTGCTGGCTTCCCTGAGCTGGTGAGATGTAC
TAAGAGGAGTATCAGGAGAAAGAGAGGAGCAGAAAGAGACTTCGAGGATTTTGAAGCCCTGCAT
GAATTCCCCAATGACATCTTCACCAATGAAGATCGAAGACAGGGGGCGGTGGTTCTCCACGTGC
TCTGCGCCATGTACATGTTCTACGCGCTGGCCATCGTGTGCGATGACTTCTTTGTCCCCTCCTT
GGAAAAGATCTGTGAGCGCCTGCATCTCAGTGAAGATGTGGCTGGGGCCACATTCATGGCAGCA
GGCAGTTCGGCCCCAGAGCTGTTCACGTCCGTCATAGGGGTCTTCATCACCAAGGGTGACGTGG
GAGTTGGGACCATCGTGGGCTCTGCAGTGTTCAATATCCTGTGCATCATTGGCGTCTGCGGGCT
CTTTGCTGGGCAGGTTGTGGCTCTTTCCTCCTGGTGCCTGCTGAGGGATTCAATTTACTACACG
CTGTCTGTGGTTGCGCTCATCGTGTTCATTTATGATGAACAAGTTTCCTGGTGGGAGTCTTTAG
TCCTCGTGCTGATGTATCTCATCTATATTGTCATCATGAAATATAACGCTTGCATCCATCAGTG
CTTCGAAAGGAGGACGAAAGGCACTGGGAACATGGTCAACGGTTTGGCCAACAATGCTGAAATT
GACGACAGCAGTAATTGTGATGCGACTGTGGTGCTACTCAAGAAAGCCAATTTCCACCGCAAAG
CATCAGTGATTATGGTAGACGAGCTGCTGTCAGCCTACCCTCACCAGCTTTCTTTCTCTGAGGC
TGGACTTCGAATAATGATCACCAGCCACTTTCCCCCCAAGACCCGACTCTCCATGGCCAGCCGC
ATGTTGATCAATGAGAGACAAAGACTGATAAACAGTAGGGCCTACGCCAATGGAGAATCTGAGG
TGGCCATCAAAATCCCAATTAAGCACACTGTGGAGAACGGGACAGGGCCCAGCAGTGCCCCAGA
CAGAGGAGTGAATGGGACTCGGAGGGATGATGTTGTTGCCGAGGCTGGTAATGAGACAGAGAAT
GAGAATGAGGACAATGAGAACAATGAGAATGACGAAGAGGAAGAGGAGGATGAGGATGATGATG
AAGGACCATACACGCCATTCGACCTCCCCTCTGGAAAACTGGAAACAGTGAAGTGGGTGTTCAC
CTGGCCACTGAGTTTTGTCTTATACTTCACTGTACCCAACTGCAACAAGCCCCGCTGGGAAAAA
TGGTTTATGGTGACATTTGCTTCTTCCACATTATGGATAGCAGCTTTCTCCTACATGATGGTGT
GGATGGTCACAATCATTGGATACACACTGGGGATTCCTGATGTCATCATGGGGATCACTTTCCT
GGCAGCTGGAACCAGTGTGCCCGATTGCATGGCCAGCCTCATTGTGGCCCGACAAGGCATGGGA
GACATGGCTGTGTCCAACTCTATTGGGAGCAATGTGTTTGATATCCTCATTGGCCTTGGTCTCC
CATGGGCCCTACAGACCCTGGCTGTGGACTATGGATCCTACATTCGGCTGAACAGCAGAGGACT
GATCTACTCCGTGGGCTTACTCCTGGCCTCCGTCTTTGTCACGGTGTTTGGCGTTCACCTGAAC
AAGTGGCAGCTGGACAAGAAGCTCGGGTGCGGGTGCCTTTTCCTGTACGGCGTGTTCCTGTGCT
TCTCCATCATGACGGAGTTCAACGTGTTCACCTTTGTGAACTTGCCCATGTGCGGGGACCACTG
ATCCGCCCGGAGGCCCGCCGAGCTGCGGTCCTCCTTTTCTGTGCAATACGAAATCCAGCCGCAC
CCCGAGTCCCGCGGGCCCCCCACCCCGGCGCCGGGGTCTCCGGTTGTCCCGCGCGGGTCCCGGG
CCTCCGCTCCTGCCTCAGTGGCCCAGGCTGCCCCCGCCCCCCTGCTCCCCCTCTCCGTGGGGC

hide sequence

RefSeq Acc Id:

XM_022409293 ⟹ XP_022265001

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	24	3,593,564 - 3,720,402 (-)	NCBI
Dog10K_Boxer_Tasha	24	3,620,103 - 3,748,525 (-)	NCBI

Sequence:

show sequence

TAAGGCTCCTATTGTAGTCTGTTGCCGGTCAGTGGAGCCAGGGGCCTACGCCAAAGCCCTGCTG
CCCCTCCATGGCTGAGCAAGGAAGTGCAGCGGCCTGCGCCACTGGGAAGAGGCGCCTGCATCTC
AGTGAAGATGTGGCTGGGGCCACATTCATGGCAGCAGGCAGTTCGGCCCCAGAGCTGTTCACGT
CCGTCATAGGGGTCTTCATCACCAAGGGTGACGTGGGAGTTGGGACCATCGTGGGCTCTGCAGT
GTTCAATATCCTGTGCATCATTGGCGTCTGCGGGCTCTTTGCTGGGCAGGTTGTGGCTCTTTCC
TCCTGGTGCCTGCTGAGGGATTCAATTTACTACACGCTGTCTGTGGTTGCGCTCATCGTGTTCA
TTTATGATGAACAAGTTTCCTGGTGGGAGTCTTTAGTCCTCGTGCTGATGTATCTCATCTATAT
TGTCATCATGAAATATAACGCTTGCATCCATCAGTGCTTCGAAAGGAGGACGAAAGGCACTGGG
AACATGGTCAACGGTTTGGCCAACAATGCTGAAATTGACGACAGCAGTAATTGTGATGCGACTG
TGGTGCTACTCAAGAAAGCCAATTTCCACCGCAAAGCATCAGTGATTATGGTAGACGAGCTGCT
GTCAGCCTACCCTCACCAGCTTTCTTTCTCTGAGGCTGGACTTCGAATAATGATCACCAGCCAC
TTTCCCCCCAAGACCCGACTCTCCATGGCCAGCCGCATGTTGATCAATGAGAGACAAAGACTGA
TAAACAGTAGGGCCTACGCCAATGGAGAATCTGAGGTGGCCATCAAAATCCCAATTAAGCACAC
TGTGGAGAACGGGACAGGGCCCAGCAGTGCCCCAGACAGAGGAGTGAATGGGACTCGGAGGGAT
GATGTTGTTGCCGAGGCTGGTAATGAGACAGAGAATGAGAATGAGGACAATGAGAACAATGAGA
ATGACGAAGAGGAAGAGGAGGATGAGGATGATGATGAAGGACCATACACGCCATTCGACCTCCC
CTCTGGAAAACTGGAAACAGTGAAGTGGGTGTTCACCTGGCCACTGAGTTTTGTCTTATACTTC
ACTGTACCCAACTGCAACAAGCCCCGCTGGGAAAAATGGTTTATGGTGACATTTGCTTCTTCCA
CATTATGGATAGCAGCTTTCTCCTACATGATGGTGTGGATGGTCACAATCATTGGATACACACT
GGGGATTCCTGATGTCATCATGGGGATCACTTTCCTGGCAGCTGGAACCAGTGTGCCCGATTGC
ATGGCCAGCCTCATTGTGGCCCGACAAGGCATGGGAGACATGGCTGTGTCCAACTCTATTGGGA
GCAATGTGTTTGATATCCTCATTGGCCTTGGTCTCCCATGGGCCCTACAGACCCTGGCTGTGGA
CTATGGATCCTACATTCGGCTGAACAGCAGAGGACTGATCTACTCCGTGGGCTTACTCCTGGCC
TCCGTCTTTGTCACGGTGTTTGGCGTTCACCTGAACAAGTGGCAGCTGGACAAGAAGCTCGGGT
GCGGGTGCCTTTTCCTGTACGGCGTGTTCCTGTGCTTCTCCATCATGACGGAGTTCAACGTGTT
CACCTTTGTGAACTTGCCCATGTGCGGGGACCACTGATCCGCCCGGAGGCCCGCCGAGCTGCGG
TCCTCCTTTTCTGTGCAATACGAAATCCAGCCGCACCCCGAGTCCCGCGGGCCCCCCACCCCGG
CGCCGGGGTCTCCGGTTGTCCCGCGCGGGTCCCGGGCCTCCGCTCCTGCCTCAGTGGCCCAGGC
TGCCCCCGCCCCCCTGCTCCCCCTCTCCGTGGG

hide sequence

RefSeq Acc Id:

XM_038432993 ⟹ XP_038288921

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	4,000,491 - 4,482,100 (-)	NCBI

RefSeq Acc Id:

XM_038432994 ⟹ XP_038288922

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	4,000,491 - 4,199,385 (-)	NCBI

RefSeq Acc Id:

XM_038432995 ⟹ XP_038288923

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	4,000,491 - 4,134,439 (-)	NCBI

RefSeq Acc Id:

XM_038432996 ⟹ XP_038288924

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	4,000,491 - 4,128,996 (-)	NCBI

RefSeq Acc Id:

XM_038457556 ⟹ XP_038313484

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	24	3,620,103 - 3,753,968 (-)	NCBI

RefSeq Acc Id:

XM_038508206 ⟹ XP_038364134

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	3,595,752 - 4,077,406 (-)	NCBI

RefSeq Acc Id:

XM_038508207 ⟹ XP_038364135

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	3,595,752 - 3,794,540 (-)	NCBI

RefSeq Acc Id:

XM_038508208 ⟹ XP_038364136

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	3,595,752 - 3,729,601 (-)	NCBI

RefSeq Acc Id:

XM_038508209 ⟹ XP_038364137

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	3,595,752 - 3,724,158 (-)	NCBI

RefSeq Acc Id:

XM_038571460 ⟹ XP_038427388

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	3,977,410 - 4,458,938 (-)	NCBI

RefSeq Acc Id:

XM_038571461 ⟹ XP_038427389

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	3,977,410 - 4,176,215 (-)	NCBI

RefSeq Acc Id:

XM_038571462 ⟹ XP_038427390

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	3,977,410 - 4,111,293 (-)	NCBI

RefSeq Acc Id:

XM_038571463 ⟹ XP_038427391

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	3,977,410 - 4,105,850 (-)	NCBI

RefSeq Acc Id:

XM_038635699 ⟹ XP_038491627

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	3,699,250 - 4,181,348 (-)	NCBI

RefSeq Acc Id:

XM_038635700 ⟹ XP_038491628

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	3,699,250 - 3,897,853 (-)	NCBI

RefSeq Acc Id:

XM_038635701 ⟹ XP_038491629

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	3,699,250 - 3,833,136 (-)	NCBI

RefSeq Acc Id:

XM_038635702 ⟹ XP_038491630

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	3,699,250 - 3,827,691 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_022265000	(Get FASTA)	NCBI Sequence Viewer
	XP_022265001	(Get FASTA)	NCBI Sequence Viewer
	XP_038288921	(Get FASTA)	NCBI Sequence Viewer
	XP_038288922	(Get FASTA)	NCBI Sequence Viewer
	XP_038288923	(Get FASTA)	NCBI Sequence Viewer
	XP_038288924	(Get FASTA)	NCBI Sequence Viewer
	XP_038313484	(Get FASTA)	NCBI Sequence Viewer
	XP_038364134	(Get FASTA)	NCBI Sequence Viewer
	XP_038364135	(Get FASTA)	NCBI Sequence Viewer
	XP_038364136	(Get FASTA)	NCBI Sequence Viewer
	XP_038364137	(Get FASTA)	NCBI Sequence Viewer
	XP_038427388	(Get FASTA)	NCBI Sequence Viewer
	XP_038427389	(Get FASTA)	NCBI Sequence Viewer
	XP_038427390	(Get FASTA)	NCBI Sequence Viewer
	XP_038427391	(Get FASTA)	NCBI Sequence Viewer
	XP_038491627	(Get FASTA)	NCBI Sequence Viewer
	XP_038491628	(Get FASTA)	NCBI Sequence Viewer
	XP_038491629	(Get FASTA)	NCBI Sequence Viewer
	XP_038491630	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000008016.6
	ENSCAFP00000038552.3
	ENSCAFP00030038691.1
	ENSCAFP00030038703.1
	ENSCAFP00030038760.1
	ENSCAFP00040039159.1
	ENSCAFP00040039174.1
	ENSCAFP00040039197.1
	ENSCAFP00845040770
	ENSCAFP00845040770.1

RefSeq Acc Id:	XP_022265000 ⟸ XM_022409292
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0TNA0 (UniProtKB/TrEMBL), A0A8P0NQ53 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNVPDTFFSPNERENTLHPLQTSIWTHQTQASGKQPGEAGQLTAVALVRGIYSLQGSVVSMGTA LLAFAGFPELVRCTKRSIRRKRGAERDFEDFEALHEFPNDIFTNEDRRQGAVVLHVLCAMYMFY ALAIVCDDFFVPSLEKICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGS AVFNILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVVALIVFIYDEQVSWWESLVLVLMYLI YIVIMKYNACIHQCFERRTKGTGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIMVDE LLSAYPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYANGESEVAIKIPIK HTVENGTGPSSAPDRGVNGTRRDDVVAEAGNETENENEDNENNENDEEEEEDEDDDEGPYTPFD LPSGKLETVKWVFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGY TLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLA VDYGSYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLFLYGVFLCFSIMTEFN VFTFVNLPMCGDH hide sequence

RefSeq Acc Id:	XP_022265001 ⟸ XM_022409293
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0PA82 (UniProtKB/TrEMBL), A0A8P0SAY2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEQGSAAACATGKRRLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFN ILCIIGVCGLFAGQVVALSSWCLLRDSIYYTLSVVALIVFIYDEQVSWWESLVLVLMYLIYIVI MKYNACIHQCFERRTKGTGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASVIMVDELLSA YPHQLSFSEAGLRIMITSHFPPKTRLSMASRMLINERQRLINSRAYANGESEVAIKIPIKHTVE NGTGPSSAPDRGVNGTRRDDVVAEAGNETENENEDNENNENDEEEEEDEDDDEGPYTPFDLPSG KLETVKWVFTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGI PDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYG SYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLFLYGVFLCFSIMTEFNVFTF VNLPMCGDH hide sequence

Ensembl Acc Id:

ENSCAFP00000038552 ⟸ ENSCAFT00000045725

Ensembl Acc Id:

ENSCAFP00000008016 ⟸ ENSCAFT00000008649

RefSeq Acc Id:	XP_038364134 ⟸ XM_038508206
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038364135 ⟸ XM_038508207
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038364136 ⟸ XM_038508208
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038364137 ⟸ XM_038508209
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038491627 ⟸ XM_038635699
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038491628 ⟸ XM_038635700
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038491629 ⟸ XM_038635701
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038491630 ⟸ XM_038635702
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038288921 ⟸ XM_038432993
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0PA74 (UniProtKB/TrEMBL), A0A8I3Q687 (UniProtKB/TrEMBL), A0A8C0PA82 (UniProtKB/TrEMBL), A0A8P0SAY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038288922 ⟸ XM_038432994
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0TNA0 (UniProtKB/TrEMBL), A0A8P0NQ53 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038288923 ⟸ XM_038432995
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0PA82 (UniProtKB/TrEMBL), A0A8P0SAY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038288924 ⟸ XM_038432996
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0PA82 (UniProtKB/TrEMBL), A0A8P0SAY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038313484 ⟸ XM_038457556
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0PA82 (UniProtKB/TrEMBL), A0A8P0SAY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038427388 ⟸ XM_038571460
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0PA74 (UniProtKB/TrEMBL), A0A8C0PA82 (UniProtKB/TrEMBL), A0A8I3Q687 (UniProtKB/TrEMBL), A0A8P0SAY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038427389 ⟸ XM_038571461
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0TNA0 (UniProtKB/TrEMBL), A0A8P0NQ53 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038427390 ⟸ XM_038571462
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0PA82 (UniProtKB/TrEMBL), A0A8P0SAY2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038427391 ⟸ XM_038571463
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0PA82 (UniProtKB/TrEMBL), A0A8P0SAY2 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845040770 ⟸ ENSCAFT00845051965

Protein Domains

Sodium/calcium exchanger membrane region

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000005373	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030024109	UniProtKB/TrEMBL
	ENSCAFG00040024050	UniProtKB/TrEMBL
	ENSCAFG00845029352	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000008649.6	UniProtKB/TrEMBL
	ENSCAFT00000045725.4	UniProtKB/TrEMBL
	ENSCAFT00030044336.1	UniProtKB/TrEMBL
	ENSCAFT00030044347.1	UniProtKB/TrEMBL
	ENSCAFT00030044411.1	UniProtKB/TrEMBL
	ENSCAFT00040044825.1	UniProtKB/TrEMBL
	ENSCAFT00040044840.1	UniProtKB/TrEMBL
	ENSCAFT00040044866.1	UniProtKB/TrEMBL
	ENSCAFT00845051965	ENTREZGENE
	ENSCAFT00845051965.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1420.30	UniProtKB/TrEMBL
InterPro	K/Na/Ca-exchanger	UniProtKB/TrEMBL
	NaCa_Exmemb	UniProtKB/TrEMBL
	NCX_ion-bd_dom_sf	UniProtKB/TrEMBL
NCBI Gene	SLC24A3	ENTREZGENE
PANTHER	PTHR10846	UniProtKB/TrEMBL
	SODIUM/POTASSIUM/CALCIUM EXCHANGER 3	UniProtKB/TrEMBL
Pfam	Na_Ca_ex	UniProtKB/TrEMBL
UniProt	A0A8C0PA74	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0PA82	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0TNA0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3Q687	ENTREZGENE, UniProtKB/TrEMBL
	A0A8P0NQ53	ENTREZGENE
	A0A8P0SAY2	ENTREZGENE
UniProt Secondary	A0A8P0NQ53	UniProtKB/TrEMBL
	A0A8P0SAY2	UniProtKB/TrEMBL
VGNC ID	VGNC:46287	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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