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Gene: ITGAV (integrin subunit alpha V) Canis lupus familiaris
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Symbol: ITGAV
Name: integrin subunit alpha V
RGD ID: 12288715
Description: ENCODES a protein that exhibits C-X3-C chemokine binding (ortholog); fibroblast growth factor binding (ortholog); insulin-like growth factor I binding (ortholog); INVOLVED IN blood vessel development (ortholog); cell migration (ortholog); cell-substrate adhesion (ortholog); PARTICIPATES IN integrin mediated signaling pathway; platelet-derived growth factor signaling pathway; sphingosine 1-phosphate signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); acute myeloid leukemia (ortholog); Cerebral Hemorrhage (ortholog); FOUND IN cell surface (ortholog); membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: integrin alpha-V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
Orthologs:
Homo sapiens (human) : ITGAV (integrin subunit alpha V)  HGNC  Alliance
Mus musculus (house mouse) : Itgav (integrin alpha V)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itgav (integrin subunit alpha V)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itgav (integrin subunit alpha V)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGAV (integrin subunit alpha V)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itgav (integrin subunit alpha V)
Sus scrofa (pig) : ITGAV (integrin subunit alpha V)
Chlorocebus sabaeus (African green monkey) : ITGAV (integrin subunit alpha V)
Heterocephalus glaber (naked mole-rat) : Itgav (integrin subunit alpha V)
more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl3628,804,013 - 28,887,430 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.13628,815,215 - 28,890,569 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - uncurated

Genomics

Comparative Map Data

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on ITGAV
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12288715
Created: 2017-01-24
Species: Canis lupus familiaris
Last Modified: 2020-09-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.