CACNA1S (calcium voltage-gated channel subunit alpha1 S) - Rat Genome Database

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Gene: CACNA1S (calcium voltage-gated channel subunit alpha1 S) Canis lupus familiaris
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Symbol: CACNA1S
Name: calcium voltage-gated channel subunit alpha1 S
RGD ID: 12411949
Description: ENCODES a protein that exhibits high voltage-gated calcium channel activity (ortholog); voltage-gated calcium channel activity (ortholog); INVOLVED IN calcium ion transport (ortholog); endoplasmic reticulum organization (ortholog); extraocular skeletal muscle development (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); hereditary neuropathy with liability to pressure palsies (ortholog); hypokalemic periodic paralysis (ortholog); FOUND IN cytoplasm (ortholog); dendritic spine head (ortholog); I band (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: voltage-dependent L-type calcium channel subunit alpha-1S
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.172,108,716 - 2,172,246 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl72,108,455 - 2,303,220 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha71,793,187 - 1,856,620 (+)NCBI
ROS_Cfam_1.071,755,440 - 1,818,918 (+)NCBI
UMICH_Zoey_3.171,738,797 - 1,802,223 (+)NCBI
UNSW_CanFamBas_1.071,841,461 - 1,904,933 (+)NCBI
UU_Cfam_GSD_1.071,871,249 - 1,934,698 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
CACNA1S
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.172,108,716 - 2,172,246 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl72,108,455 - 2,303,220 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha71,793,187 - 1,856,620 (+)NCBI
ROS_Cfam_1.071,755,440 - 1,818,918 (+)NCBI
UMICH_Zoey_3.171,738,797 - 1,802,223 (+)NCBI
UNSW_CanFamBas_1.071,841,461 - 1,904,933 (+)NCBI
UU_Cfam_GSD_1.071,871,249 - 1,934,698 (+)NCBI
CACNA1S
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1201,039,512 - 201,112,451 (-)EnsemblGRCh38hg38GRCh38
GRCh381201,039,509 - 201,112,453 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371201,008,640 - 201,081,554 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361199,275,263 - 199,348,317 (-)NCBINCBI36hg18NCBI36
Build 341197,740,298 - 197,813,351NCBI
Celera1174,132,677 - 174,205,677 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1172,175,337 - 172,248,318 (-)NCBIHuRef
CHM1_11202,431,280 - 202,504,354 (-)NCBICHM1_1
Cacna1s
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,980,261 - 136,047,560 (+)NCBIGRCm39mm39
GRCm39 Ensembl1135,980,488 - 136,047,560 (+)Ensembl
GRCm381136,052,806 - 136,119,822 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1136,052,750 - 136,119,822 (+)EnsemblGRCm38mm10GRCm38
MGSCv371137,949,478 - 138,016,399 (+)NCBIGRCm37mm9NCBIm37
MGSCv361137,869,312 - 137,936,233 (+)NCBImm8
Celera1138,687,405 - 138,754,983 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map159.55NCBI
Cacna1s
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21347,493,949 - 47,564,194 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1347,493,949 - 47,564,318 (+)Ensembl
Rnor_6.01352,889,570 - 52,964,558 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1352,889,737 - 52,964,155 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01357,945,479 - 58,018,760 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41349,096,012 - 49,103,925 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1347,809,765 - 47,877,622 (+)NCBICelera
Cytogenetic Map13q13NCBI
Cacna1s
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540637,201,180 - 37,263,371 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540637,201,180 - 37,263,328 (-)NCBIChiLan1.0ChiLan1.0
CACNA1S
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11180,941,836 - 181,014,823 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1180,941,836 - 181,014,823 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01176,639,189 - 176,712,171 (-)NCBIMhudiblu_PPA_v0panPan3
Cacna1s
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934474,034,420 - 74,097,190 (+)NCBI
SpeTri2.0NW_0049365673,269,283 - 3,331,858 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CACNA1S
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1023,502,898 - 23,568,032 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11023,503,701 - 23,567,797 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21027,934,779 - 27,999,415 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CACNA1S
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12528,288,483 - 28,363,231 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2528,289,342 - 28,363,327 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605529,088,659 - 29,162,753 (+)NCBIVero_WHO_p1.0
Cacna1s
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248079,560,004 - 9,618,942 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6
Low 6 8
Below cutoff 5 5 19 6 6 6 6 6 9 5

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000017400   ⟹   ENSCAFP00000016109
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl72,108,455 - 2,172,240 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000069759   ⟹   ENSCAFP00000044918
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl72,108,455 - 2,303,220 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000081666   ⟹   ENSCAFP00000062804
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl72,108,455 - 2,173,028 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000088899   ⟹   ENSCAFP00000051520
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl72,117,174 - 2,303,220 (+)Ensembl
RefSeq Acc Id: XM_005622266   ⟹   XP_005622323
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.172,108,829 - 2,172,246 (+)NCBI
Dog10K_Boxer_Tasha71,793,280 - 1,856,620 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038480597   ⟹   XP_038336525
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.171,738,797 - 1,802,223 (+)NCBI
RefSeq Acc Id: XM_038480598   ⟹   XP_038336526
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.171,738,890 - 1,802,223 (+)NCBI
RefSeq Acc Id: XM_038541920   ⟹   XP_038397848
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.071,871,249 - 1,934,698 (+)NCBI
RefSeq Acc Id: XM_038541921   ⟹   XP_038397849
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.071,871,342 - 1,934,698 (+)NCBI
RefSeq Acc Id: XM_038606054   ⟹   XP_038461982
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.071,841,461 - 1,904,933 (+)NCBI
RefSeq Acc Id: XM_038606055   ⟹   XP_038461983
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.071,841,554 - 1,904,933 (+)NCBI
RefSeq Acc Id: XM_038670756   ⟹   XP_038526684
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.071,755,440 - 1,818,918 (+)NCBI
RefSeq Acc Id: XM_038670758   ⟹   XP_038526686
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.071,755,530 - 1,818,918 (+)NCBI
RefSeq Acc Id: XM_843592   ⟹   XP_848685
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.172,108,716 - 2,172,246 (+)NCBI
Dog10K_Boxer_Tasha71,793,187 - 1,856,620 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_848685   ⟸   XM_843592
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005622323   ⟸   XM_005622266
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000051520   ⟸   ENSCAFT00000088899
RefSeq Acc Id: ENSCAFP00000044918   ⟸   ENSCAFT00000069759
RefSeq Acc Id: ENSCAFP00000016109   ⟸   ENSCAFT00000017400
RefSeq Acc Id: ENSCAFP00000062804   ⟸   ENSCAFT00000081666
RefSeq Acc Id: XP_038336525   ⟸   XM_038480597
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038336526   ⟸   XM_038480598
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038461982   ⟸   XM_038606054
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038461983   ⟸   XM_038606055
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038526684   ⟸   XM_038670756
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038526686   ⟸   XM_038670758
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038397848   ⟸   XM_038541920
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038397849   ⟸   XM_038541921
- Peptide Label: isoform X2

Promoters
RGD ID:13683871
Promoter ID:EPDNEW_C1941
Type:single initiation site
Name:CACNA1S_1
Description:calcium voltage-gated channel subunit alpha1 S
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.172,108,631 - 2,108,691EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010884 Ensembl, ENTREZGENE
NCBI Gene CACNA1S ENTREZGENE
VGNC ID VGNC:38640 ENTREZGENE