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ONTOLOGY REPORT - ANNOTATIONS

Term:response to amphetamine
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Accession:GO:0001975 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.


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response to amphetamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11172060) Ensembl
MGI		 PMID:11172060 GO_REF:0000107 NCBI chr14:49,467,186...49,485,845
Ensembl chr14:49,468,877...49,485,850 		JBrowse link
G ADRA1B adrenoceptor alpha 1B acts_upstream_of_or_within ISO (PMID:11923452), (PMID:12871582) MGI PMID:11923452 PMID:12871582 NCBI chr16:63,550,123...64,010,838
Ensembl chr16:63,550,130...63,603,034 		JBrowse link
G ASIC1 acid sensing ion channel subunit 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25828470) Ensembl
MGI		 PMID:25828470 GO_REF:0000107 NCBI chr 5:15,965,082...15,991,291
Ensembl chr 5:15,965,084...15,991,876 		JBrowse link
G CALM1 calmodulin 1 ISO RGD PMID:10854758 RGD:6892957 NCBI chr 7:112,160,823...112,171,754
Ensembl chr 7:112,160,806...112,171,744 		JBrowse link
G CALM2 calmodulin 2 ISO RGD PMID:10854758 RGD:6892957 NCBI chr 3:93,371,765...93,386,378
Ensembl chr 3:93,372,045...93,386,218 		JBrowse link
G CALM3 calmodulin 3 ISO RGD PMID:10854758 RGD:6892957 NCBI chr 6:52,506,979...52,516,704
Ensembl chr 6:52,506,674...52,516,703 		JBrowse link
G CNR2 cannabinoid receptor 2 ISO RGD PMID:20067581 RGD:2316187 NCBI chr 6:81,659,162...81,692,550
Ensembl chr 6:81,659,169...81,692,550 		JBrowse link
G COMT catechol-O-methyltransferase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23169629) Ensembl
MGI		 PMID:23169629 GO_REF:0000107 NCBI chr14:51,384,729...51,403,997
Ensembl chr14:51,385,738...51,403,998 		JBrowse link
G CXCL2 chemokine (C-X-C motif) ligand 2 ISO RGD PMID:19582783 RGD:2314489 NCBI chr 8:70,157,253...70,159,145
Ensembl chr 8:70,157,214...70,159,138 		JBrowse link
G DBH dopamine beta-hydroxylase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12370425) Ensembl
MGI		 PMID:12370425 GO_REF:0000107 NCBI chr 1:273,204,407...273,225,562
Ensembl chr 1:273,204,175...273,225,552 		JBrowse link
G DCC DCC netrin 1 receptor ISO RGD PMID:17996376 RGD:2314370 NCBI chr 1:101,518,629...103,087,021
Ensembl chr 1:101,846,100...103,083,096 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO RGD PMID:17105900 RGD:1599727 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829 		JBrowse link
G DPYSL2 dihydropyrimidinase like 2 ISO RGD PMID:20058175 RGD:2316239 NCBI chr14:10,428,598...10,545,705
Ensembl chr14:10,427,957...10,545,704 		JBrowse link
G DRD1 dopamine receptor D1 acts_upstream_of_or_within ISO (PMID:21368124)
(PMID:11823893)
(PMID:12097513)
(PMID:10661513)
(PMID:16014726)
(PMID:18486343), (PMID:9261820)
(PMID:10222120)		 RGD
MGI		 PMID:9261820 PMID:10222120 PMID:10661513 PMID:11823893 PMID:12097513 More... RGD:2311558 NCBI chr16:49,189,555...49,193,722
Ensembl chr16:49,189,602...49,191,976 		JBrowse link
G DRD2 dopamine receptor D2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:12097513)
(PMID:18486343)		 RGD
Ensembl
MGI		 PMID:12097513 PMID:18486343 PMID:19145071 GO_REF:0000107 RGD:2311558 NCBI chr 9:41,068,618...41,135,262
Ensembl chr 9:41,068,779...41,133,599 		JBrowse link
G DRD3 dopamine receptor D3 acts_upstream_of_or_within ISO (PMID:12097513) MGI PMID:12097513 NCBI chr13:145,769,294...145,817,997
Ensembl chr13:145,771,774...145,819,168 		JBrowse link
G DRD4 dopamine receptor D4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9323127) Ensembl
MGI		 PMID:9323127 GO_REF:0000107 NCBI chr 2:398,766...401,539
Ensembl chr 2:398,766...402,433 		JBrowse link
G DRD5 dopamine receptor D5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11823893) Ensembl
MGI		 PMID:11823893 GO_REF:0000107 NCBI chr 8:6,180,221...6,182,575
Ensembl chr 8:6,180,221...6,181,636 		JBrowse link
G EDN1 endothelin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G EDNRA endothelin receptor type A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:81,210,750...81,279,053
Ensembl chr 8:81,209,327...81,276,853 		JBrowse link
G EGR1 early growth response 1 ISO methamphetamine RGD PMID:21229349 RGD:5131852 NCBI chr 2:140,440,829...140,445,302
Ensembl chr 2:140,441,421...140,445,296 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:31373119 RGD:401900735 NCBI chr 6:51,836,780...51,844,531
Ensembl chr 6:51,837,719...51,844,529 		JBrowse link
G GNAL G protein subunit alpha L acts_upstream_of_or_within ISO (PMID:11404425) MGI PMID:11404425 NCBI chr 6:97,342,468...97,429,334
Ensembl chr 6:97,342,474...97,429,364 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 acts_upstream_of_or_within ISO (PMID:21368124)
(PMID:15467708), (PMID:16638606)		 MGI PMID:15467708 PMID:16638606 PMID:21368124
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15731593) Ensembl
MGI		 PMID:15731593 GO_REF:0000107 NCBI chr 3:32,749,329...33,149,350
Ensembl chr 3:32,750,700...33,143,499 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:20422365 RGD:4107018 NCBI chr 5:58,477,862...58,948,735
Ensembl chr 5:58,480,528...58,927,558 		JBrowse link
G HDAC1 histone deacetylase 1 ISO RGD PMID:18632938 RGD:9586741 NCBI chr 6:88,749,611...88,785,220
Ensembl chr 6:88,749,634...88,785,411 		JBrowse link
G HDAC2 histone deacetylase 2 ISO RGD PMID:22470541 RGD:9590269 NCBI chr 1:79,867,713...79,901,597
Ensembl chr 1:79,863,094...79,901,585 		JBrowse link
G HDAC6 histone deacetylase 6 ISO RGD PMID:25452209 RGD:9681719 NCBI chr  X:42,917,911...42,941,894
Ensembl chr  X:42,917,964...42,941,887 		JBrowse link
G HDAC9 histone deacetylase 9 ISO RGD PMID:25452209 RGD:9681719 NCBI chr 9:87,164,400...88,192,803
Ensembl chr 9:87,449,359...88,186,961 		JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1432691), (PMID:1777100) Ensembl
MGI		 PMID:1432691 PMID:1777100 GO_REF:0000107 NCBI chr  X:110,321,144...110,357,902
Ensembl chr  X:110,321,204...110,357,894 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:21093552 RGD:4889145 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205 		JBrowse link
G LOC100511376 E3 SUMO-protein ligase RanBP2 ISO methamphetamine RGD PMID:23711322 RGD:9835030 NCBI chr 3:47,531,362...47,601,328
Ensembl chr 3:47,531,359...47,601,495 		JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12385813) Ensembl
MGI		 PMID:12385813 GO_REF:0000107 NCBI chr15:63,487,051...63,506,249
Ensembl chr15:63,487,731...63,495,299 		JBrowse link
G NTS neurotensin ISO RGD PMID:9786410 RGD:9698453 NCBI chr 5:96,261,299...96,272,947
Ensembl chr 5:96,260,560...96,272,976 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:17383105 RGD:2304140 NCBI chr17:32,605,586...32,606,449
Ensembl chr17:32,605,586...32,606,546 		JBrowse link
G OXTR oxytocin receptor ISO RGD PMID:17383105 RGD:2304140 NCBI chr13:65,134,055...65,155,543
Ensembl chr13:65,134,057...65,153,487 		JBrowse link
G PDE1B phosphodiesterase 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17010100)
(PMID:17559891)		 Ensembl
MGI		 PMID:17010100 PMID:17559891 GO_REF:0000107 NCBI chr 5:19,725,346...19,752,892
Ensembl chr 5:19,725,415...19,752,888 		JBrowse link
G PPP1R1B protein phosphatase 1 regulatory inhibitor subunit 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18496528)
(PMID:17010100)		 Ensembl
MGI		 PMID:17010100 PMID:18496528 GO_REF:0000107 NCBI chr12:22,681,244...22,690,978
Ensembl chr12:22,680,980...22,690,952 		JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B ISO RGD PMID:19932152 RGD:9999394 NCBI chr12:26,319,123...26,337,089
Ensembl chr12:26,319,124...26,336,562 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha ISO reduced protein in brain striatum particulate fraction, unchanged in soluble fraction, of methamphetamine-treated rats RGD PMID:11954050 RGD:727362 NCBI chr 8:119,429,181...119,754,615
Ensembl chr 8:119,428,779...119,753,105 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta ISO reduced protein in brain striatum particulate fraction, unchanged in soluble fraction, of methamphetamine-treated rats RGD PMID:11954050 RGD:727362 NCBI chr14:76,239,497...76,305,345
Ensembl chr14:76,248,841...76,305,328 		JBrowse link
G PTPN5 protein tyrosine phosphatase non-receptor type 5 ISO RGD PMID:23711322 RGD:9835030 NCBI chr 2:40,458,865...40,521,470
Ensembl chr 2:40,459,049...40,521,461 		JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 ISO RGD PMID:19686726 RGD:10003122 NCBI chr 7:48,121,415...48,246,749
Ensembl chr 7:48,121,419...48,246,749 		JBrowse link
G RGS10 regulator of G protein signaling 10 ISO RGD PMID:26321241 RGD:13524514 NCBI chr14:129,386,717...129,424,150
Ensembl chr14:129,381,208...129,423,702 		JBrowse link
G RGS17 regulator of G protein signaling 17 ISO RGD PMID:26321241 RGD:13524514 NCBI chr 1:13,340,253...13,442,058
Ensembl chr 1:13,340,355...13,442,039 		JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:26321241 RGD:13524514 NCBI chr10:936,836...940,083
Ensembl chr10:936,789...940,098 		JBrowse link
G RGS20 regulator of G protein signaling 20 ISO RGD PMID:26321241 RGD:13524514 NCBI chr 4:77,141,935...77,185,209
Ensembl chr 4:77,141,945...77,209,533 		JBrowse link
G RGS4 regulator of G protein signaling 4 ISO RGD PMID:26321241 RGD:13524514 NCBI chr 4:87,383,336...87,390,478
Ensembl chr 4:87,383,345...87,390,893 		JBrowse link
G RGS7 regulator of G protein signaling 7 ISO RGD PMID:26321241 RGD:13524514 NCBI chr10:11,950,897...12,322,382
Ensembl chr10:11,950,901...12,322,359 		JBrowse link
G RGS8 regulator of G protein signaling 8 ISO RGD PMID:26321241 RGD:13524514 NCBI chr 9:123,937,721...124,053,927
Ensembl chr 9:123,955,241...124,047,648 		JBrowse link
G RGS9 regulator of G protein signaling 9 ISO RGD PMID:26321241 RGD:13524514 NCBI chr12:12,015,321...12,087,982
Ensembl chr12:12,015,321...12,087,976 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 methamphetamine
(PMID:9275230)		 RGD
Ensembl
MGI		 PMID:9275230 PMID:21159748 GO_REF:0000107 RGD:5130776 NCBI chr14:127,357,605...127,394,242
Ensembl chr14:127,357,555...127,396,533 		JBrowse link
G SLC1A1 solute carrier family 1 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:217,366,493...217,441,643
Ensembl chr 1:217,366,499...217,441,674 		JBrowse link
G SOD1 superoxide dismutase 1 ISO RGD PMID:18452277 RGD:2302826 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
G TH tyrosine hydroxylase ISO RGD PMID:21078367 RGD:5128808 NCBI chr 2:1,499,628...1,506,180
Ensembl chr 2:1,499,620...1,506,170 		JBrowse link
G TRDMT1 tRNA aspartic acid methyltransferase 1 ISO RGD PMID:15542706 RGD:2303196 NCBI chr10:43,434,148...43,494,924
Ensembl chr10:43,434,444...43,493,892 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17806
    response to stimulus 10062
      response to chemical 5870
        response to nitrogen compound 1489
          response to organonitrogen compound 1372
            response to amine 88
              response to amphetamine 57
                cellular response to amphetamine 0
paths to the root