PPP1R9B (protein phosphatase 1 regulatory subunit 9B) - Rat Genome Database

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Gene: PPP1R9B (protein phosphatase 1 regulatory subunit 9B) Sus scrofa
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Symbol: PPP1R9B
Name: protein phosphatase 1 regulatory subunit 9B
RGD ID: 13865641
Description: ENCODES a protein that exhibits actin binding (ortholog); actin filament binding (ortholog); D2 dopamine receptor binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); actin filament organization (ortholog); aging (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); Cognitive Dysfunction (ortholog); Colorectal Neoplasms (ortholog); FOUND IN actin cytoskeleton (ortholog); cytoplasm (ortholog); cytoplasmic side of dendritic spine plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOW QUALITY PROTEIN: neurabin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1226,319,124 - 26,336,562 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11226,319,123 - 26,337,089 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21226,358,245 - 26,375,863 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin filament depolymerization  (ISO)
actin filament organization  (IBA,ISO)
aging  (ISO)
calcium-mediated signaling  (IBA,ISO)
cell migration  (IEA)
cellular response to epidermal growth factor stimulus  (ISO)
cellular response to estradiol stimulus  (ISO)
cellular response to morphine  (IEA)
cellular response to organic cyclic compound  (ISO)
cellular response to peptide  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cerebral cortex development  (ISO)
dendrite development  (IEA,ISO)
developmental process involved in reproduction  (ISO)
filopodium assembly  (IEA)
hippocampus development  (ISO)
learning  (ISO)
male mating behavior  (ISO)
modulation of chemical synaptic transmission  (IEA)
negative regulation of cell growth  (IEA)
negative regulation of phosphoprotein phosphatase activity  (ISO)
neuron projection development  (IBA)
positive regulation of protein localization  (ISO)
positive regulation of protein localization to actin cortical patch  (ISO)
positive regulation of protein localization to plasma membrane  (ISO)
protein localization to actin cytoskeleton  (ISO)
protein localization to cell periphery  (ISO)
regulation of cell population proliferation  (IEA)
regulation of opioid receptor signaling pathway  (IEA)
regulation of protein phosphorylation  (IEA,ISO)
reproductive system development  (ISO)
response to amino acid  (ISO)
response to amphetamine  (ISO)
response to clozapine  (ISO)
response to estradiol  (ISO)
response to immobilization stress  (ISO)
response to kainic acid  (ISO)
response to L-phenylalanine derivative  (ISO)
response to nicotine  (ISO)
response to organic cyclic compound  (ISO)
response to organonitrogen compound  (ISO)
response to prostaglandin E  (ISO)
response to steroid hormone  (ISO)
response to xenobiotic stimulus  (ISO)

References

Genomics

Comparative Map Data
PPP1R9B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1226,319,124 - 26,336,562 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11226,319,123 - 26,337,089 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21226,358,245 - 26,375,863 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PPP1R9B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1750,133,737 - 50,150,677 (-)EnsemblGRCh38hg38GRCh38
GRCh381750,133,737 - 50,150,677 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371748,211,101 - 48,228,038 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361745,566,100 - 45,582,876 (-)NCBINCBI36hg18NCBI36
Build 341745,567,694 - 45,582,873NCBI
Celera1744,671,218 - 44,687,998 (-)NCBI
Cytogenetic Map17q21.33NCBI
HuRef1743,578,978 - 43,595,756 (-)NCBIHuRef
CHM1_11748,275,419 - 48,292,198 (-)NCBICHM1_1
Ppp1r9b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391194,882,038 - 94,897,724 (+)NCBIGRCm39mm39
GRCm39 Ensembl1194,881,861 - 94,897,725 (+)Ensembl
GRCm381194,991,212 - 95,006,898 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1194,991,035 - 95,006,899 (+)EnsemblGRCm38mm10GRCm38
MGSCv371194,852,526 - 94,868,212 (+)NCBIGRCm37mm9NCBIm37
MGSCv361194,807,302 - 94,822,974 (+)NCBImm8
Celera11104,604,585 - 104,620,251 (+)NCBICelera
Cytogenetic Map11DNCBI
Ppp1r9b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21079,938,055 - 79,954,085 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1079,938,066 - 79,954,083 (+)Ensembl
Rnor_6.01082,800,704 - 82,816,735 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1082,800,704 - 82,816,731 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01082,616,223 - 82,632,356 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41083,674,797 - 83,690,639 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11083,689,166 - 83,705,009 (+)NCBI
Celera1078,712,214 - 78,727,757 (+)NCBICelera
Cytogenetic Map10q26NCBI
Ppp1r9b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545111,516,548 - 11,530,830 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545111,516,548 - 11,530,263 (+)NCBIChiLan1.0ChiLan1.0
PPP1R9B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11749,098,089 - 49,129,659 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1749,098,089 - 49,126,932 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01744,224,007 - 44,240,906 (-)NCBIMhudiblu_PPA_v0panPan3
PPP1R9B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1926,135,982 - 26,152,303 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl926,137,464 - 26,151,810 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha925,529,124 - 25,544,951 (-)NCBI
ROS_Cfam_1.0926,930,469 - 26,946,307 (-)NCBI
UMICH_Zoey_3.1925,698,261 - 25,714,094 (-)NCBI
UNSW_CanFamBas_1.0925,956,940 - 25,972,777 (-)NCBI
UU_Cfam_GSD_1.0926,086,858 - 26,102,695 (-)NCBI
Ppp1r9b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560225,560,948 - 25,577,086 (-)NCBI
SpeTri2.0NW_00493649011,497,389 - 11,514,191 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPP1R9B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11643,188,400 - 43,205,621 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1643,188,022 - 43,205,680 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607713,904,402 - 13,921,606 (+)NCBIVero_WHO_p1.0
Ppp1r9b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247956,124,273 - 6,137,776 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 9 3 3 5 2 23 2 3
Low 1 1 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000019143   ⟹   ENSSSCP00000018637
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1226,319,124 - 26,336,562 (-)Ensembl
RefSeq Acc Id: XM_003131593   ⟹   XP_003131641
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11226,319,123 - 26,337,089 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003131641 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_003131641   ⟸   XM_003131593
- Sequence:
RefSeq Acc Id: ENSSSCP00000018637   ⟸   ENSSSCT00000019143
Protein Domains
PDZ


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000017584 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000018637 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000019143 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
InterPro NEB2 UniProtKB/TrEMBL
  Neurabin-1/2_PDZ UniProtKB/TrEMBL
  Neurabin-like UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
KEGG Report ssc:100516875 UniProtKB/TrEMBL
NCBI Gene PPP1R9B ENTREZGENE
PANTHER PTHR16154 UniProtKB/TrEMBL
  PTHR16154:SF24 UniProtKB/TrEMBL
Pfam PDZ UniProtKB/TrEMBL
  PDZ_5 UniProtKB/TrEMBL
PROSITE PDZ UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/TrEMBL
UniProt A0A480L9H7_PIG UniProtKB/TrEMBL
  F1RT57_PIG UniProtKB/TrEMBL
VGNC ID VGNC:91744 ENTREZGENE