RGS10 (regulator of G protein signaling 10) - Rat Genome Database

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Gene: RGS10 (regulator of G protein signaling 10) Sus scrofa
Analyze
Symbol: RGS10
Name: regulator of G protein signaling 10
RGD ID: 13964449
Description: ENCODES a protein that exhibits G-protein alpha-subunit binding (inferred); GTPase activator activity (inferred); INVOLVED IN positive regulation of GTPase activity (ortholog); response to amphetamine (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); Experimental Seizures (ortholog); opioid abuse (ortholog); FOUND IN axon terminus (ortholog); dendritic spine (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: regulator of G-protein signaling 10; regulator of G-protein signalling 10
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14129,381,208 - 129,423,702 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114129,386,717 - 129,424,150 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214140,910,188 - 140,948,437 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463   PMID:15265077   PMID:17145712   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
RGS10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14129,381,208 - 129,423,702 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114129,386,717 - 129,424,150 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214140,910,188 - 140,948,437 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RGS10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810119,499,817 - 119,542,719 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10119,499,817 - 119,542,719 (-)EnsemblGRCh38hg38GRCh38
GRCh3710121,259,329 - 121,302,231 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610121,249,329 - 121,292,212 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410121,249,329 - 121,286,035NCBI
Celera10114,987,371 - 115,030,248 (-)NCBICelera
Cytogenetic Map10q26.11NCBI
HuRef10114,886,926 - 114,929,790 (-)NCBIHuRef
CHM1_110121,543,774 - 121,586,656 (-)NCBICHM1_1
T2T-CHM13v2.010120,395,411 - 120,438,320 (-)NCBIT2T-CHM13v2.0
Rgs10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397127,975,345 - 128,020,993 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7127,975,345 - 128,020,482 (-)EnsemblGRCm39 Ensembl
GRCm387128,373,621 - 128,419,506 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7128,373,621 - 128,418,758 (-)EnsemblGRCm38mm10GRCm38
MGSCv377135,517,139 - 135,561,686 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367128,164,773 - 128,209,320 (-)NCBIMGSCv36mm8
Celera7128,211,923 - 128,256,406 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map770.16NCBI
Rgs10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,376,772 - 192,422,640 (-)NCBIGRCr8
mRatBN7.21182,946,334 - 182,987,729 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,946,336 - 182,987,697 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,296,809 - 191,338,111 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01198,482,897 - 198,524,198 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01191,152,753 - 191,193,909 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01199,782,076 - 199,823,440 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,782,078 - 199,823,386 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,829,264 - 206,870,593 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,622,488 - 187,664,295 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11187,784,655 - 187,797,931 (-)NCBI
Celera1180,591,534 - 180,632,893 (-)NCBICelera
Cytogenetic Map1q37NCBI
Rgs10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955551318,517 - 340,418 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955551318,229 - 348,578 (-)NCBIChiLan1.0ChiLan1.0
RGS10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28131,358,437 - 131,401,517 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110131,363,783 - 131,406,867 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010116,070,326 - 116,113,422 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110119,492,112 - 119,534,443 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10119,492,159 - 119,534,443 (-)Ensemblpanpan1.1panPan2
RGS10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12829,673,357 - 29,711,887 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2829,673,374 - 29,713,908 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2829,814,817 - 29,854,624 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02830,203,886 - 30,243,308 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2830,203,399 - 30,244,653 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12829,757,423 - 29,797,210 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02829,778,362 - 29,817,681 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02829,972,269 - 30,012,076 (-)NCBIUU_Cfam_GSD_1.0
Rgs10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721316,657,115 - 16,693,971 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364868,866,474 - 8,904,744 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364868,867,327 - 8,904,161 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGS10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19112,288,352 - 112,330,455 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9112,288,596 - 112,315,220 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604873,560,439 - 73,602,441 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgs10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473727,284,131 - 27,321,642 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473727,284,123 - 27,319,169 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in RGS10
1405 total Variants

Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
10 4 23 3 2 5 14 12 23 3 6 3

Sequence


Ensembl Acc Id: ENSSSCT00000041381   ⟹   ENSSSCP00000048629
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl14129,381,209 - 129,423,702 (-)Ensembl
Ensembl Acc Id: ENSSSCT00000047393   ⟹   ENSSSCP00000037430
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl14129,381,208 - 129,417,445 (-)Ensembl
RefSeq Acc Id: XM_001927416   ⟹   XP_001927451
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114129,386,717 - 129,424,150 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003359382   ⟹   XP_003359430
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.114129,386,717 - 129,417,953 (-)NCBI
Sequence:
RefSeq Acc Id: XP_001927451   ⟸   XM_001927416
- Peptide Label: isoform X2
- UniProtKB: A0A287AXG0 (UniProtKB/TrEMBL),   A0A4X1SUG4 (UniProtKB/TrEMBL),   A0A8D1BGQ8 (UniProtKB/TrEMBL),   A0A8D0LEN3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003359430   ⟸   XM_003359382
- Peptide Label: isoform X1
- UniProtKB: A0A4X1SW67 (UniProtKB/TrEMBL),   A0A287A104 (UniProtKB/TrEMBL),   A0A8D1BMC4 (UniProtKB/TrEMBL),   A0A8D2CJN3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSSCP00000048629   ⟸   ENSSSCT00000041381
Ensembl Acc Id: ENSSSCP00000037430   ⟸   ENSSSCT00000047393
Protein Domains
RGS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000039838 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015015364 UniProtKB/TrEMBL
  ENSSSCG00025010625 UniProtKB/TrEMBL
  ENSSSCG00030015428 UniProtKB/TrEMBL
  ENSSSCG00035078098 UniProtKB/TrEMBL
  ENSSSCG00040044612 UniProtKB/TrEMBL
  ENSSSCG00050014341 UniProtKB/TrEMBL
  ENSSSCG00055004650 UniProtKB/TrEMBL
  ENSSSCG00060040896 UniProtKB/TrEMBL
  ENSSSCG00065079006 UniProtKB/TrEMBL
  ENSSSCG00070004275 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000041381 ENTREZGENE
  ENSSSCT00000041381.3 UniProtKB/TrEMBL
  ENSSSCT00000047393 ENTREZGENE
  ENSSSCT00000047393.3 UniProtKB/TrEMBL
  ENSSSCT00015020338.1 UniProtKB/TrEMBL
  ENSSSCT00015020383.1 UniProtKB/TrEMBL
  ENSSSCT00025013980.1 UniProtKB/TrEMBL
  ENSSSCT00030021325.1 UniProtKB/TrEMBL
  ENSSSCT00035106543.1 UniProtKB/TrEMBL
  ENSSSCT00035106574.1 UniProtKB/TrEMBL
  ENSSSCT00040059835.1 UniProtKB/TrEMBL
  ENSSSCT00040059915.1 UniProtKB/TrEMBL
  ENSSSCT00050019372.1 UniProtKB/TrEMBL
  ENSSSCT00055009177.1 UniProtKB/TrEMBL
  ENSSSCT00060055415.1 UniProtKB/TrEMBL
  ENSSSCT00065109784.1 UniProtKB/TrEMBL
  ENSSSCT00065109787.1 UniProtKB/TrEMBL
  ENSSSCT00070008065.1 UniProtKB/TrEMBL
  ENSSSCT00070008075.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/TrEMBL
  1.10.196.10 UniProtKB/TrEMBL
InterPro RGS UniProtKB/TrEMBL
  RGS10/12/14-like UniProtKB/TrEMBL
  RGS10_RGS UniProtKB/TrEMBL
  RGS_sf UniProtKB/TrEMBL
  RGS_subdom1/3 UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/TrEMBL
KEGG Report ssc:100152559 UniProtKB/TrEMBL
NCBI Gene RGS10 ENTREZGENE
PANTHER REGULATOR OF G-PROTEIN SIGNALING LOCO UniProtKB/TrEMBL
  REGULATOR OF G-PROTEIN SIGNALING LOCO UniProtKB/TrEMBL
Pfam RGS UniProtKB/TrEMBL
PRINTS RGSPROTEIN UniProtKB/TrEMBL
PROSITE RGS UniProtKB/TrEMBL
SMART RGS UniProtKB/TrEMBL
Superfamily-SCOP SSF48097 UniProtKB/TrEMBL
UniProt A0A287A104 ENTREZGENE
  A0A287AXG0 ENTREZGENE
  A0A4X1SUG4 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1SW67 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0LEN3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1BGQ8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1BMC4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D2CJN3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A287A104 UniProtKB/TrEMBL
  A0A287AXG0 UniProtKB/TrEMBL
VGNC ID VGNC:92259 ENTREZGENE