GNAL (G protein subunit alpha L) - Rat Genome Database

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Gene: GNAL (G protein subunit alpha L) Sus scrofa
Analyze
Symbol: GNAL
Name: G protein subunit alpha L
RGD ID: 13982123
Description: ENCODES a protein that exhibits G-protein beta/gamma-subunit complex binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN activation of adenylate cyclase activity (ortholog); adenylate cyclase-activating dopamine receptor signaling pathway (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); PARTICIPATES IN dopamine signaling pathway via D1 family of receptors; endothelin signaling pathway; G protein mediated signaling pathway via Galphas family; ASSOCIATED WITH Brain Injuries, Traumatic (ortholog); chromosome 18p deletion syndrome (ortholog); Dysarthria (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: guanine nucleotide-binding protein G(olf) subunit alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl697,342,474 - 97,429,364 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1697,342,468 - 97,429,334 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2690,674,125 - 90,703,582 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
GNAL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl697,342,474 - 97,429,364 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1697,342,468 - 97,429,334 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2690,674,125 - 90,703,582 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GNAL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1811,689,264 - 11,885,685 (+)EnsemblGRCh38hg38GRCh38
GRCh381811,689,015 - 11,885,685 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371811,689,263 - 11,885,684 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361811,679,263 - 11,871,922 (+)NCBINCBI36hg18NCBI36
Build 341811,679,264 - 11,871,919NCBI
Celera1811,568,478 - 11,764,014 (+)NCBI
Cytogenetic Map18p11.21NCBI
HuRef1811,644,058 - 11,840,338 (+)NCBIHuRef
CHM1_11811,688,387 - 11,885,176 (+)NCBICHM1_1
Gnal
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391867,221,369 - 67,359,863 (+)NCBIGRCm39mm39
GRCm39 Ensembl1867,221,287 - 67,359,863 (+)Ensembl
GRCm381867,088,298 - 67,226,792 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1867,088,216 - 67,226,792 (+)EnsemblGRCm38mm10GRCm38
MGSCv371867,247,990 - 67,386,446 (+)NCBIGRCm37mm9NCBIm37
MGSCv361867,213,705 - 67,349,624 (+)NCBImm8
Celera1868,356,933 - 68,494,863 (+)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1839.85NCBI
Gnal
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21860,622,311 - 60,762,599 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1860,622,311 - 60,762,599 (+)Ensembl
Rnor_6.01862,805,406 - 62,946,133 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1862,805,410 - 62,944,630 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01861,991,738 - 62,131,420 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41863,595,606 - 63,735,803 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11863,668,806 - 63,809,004 (+)NCBI
Celera1858,730,137 - 58,870,361 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Gnal
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554021,181,133 - 1,248,616 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554021,182,515 - 1,249,301 (-)NCBIChiLan1.0ChiLan1.0
GNAL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1184,684,622 - 4,818,026 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0182,420,578 - 2,615,947 (-)NCBIMhudiblu_PPA_v0panPan3
GNAL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1777,378,134 - 77,521,215 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl777,413,986 - 77,521,042 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha776,779,701 - 76,925,568 (+)NCBI
ROS_Cfam_1.0777,435,802 - 77,579,609 (+)NCBI
UMICH_Zoey_3.1777,133,536 - 77,276,782 (+)NCBI
UNSW_CanFamBas_1.0777,179,815 - 77,323,366 (+)NCBI
UU_Cfam_GSD_1.0777,466,820 - 77,610,501 (+)NCBI
Gnal
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049441,140,980 - 1,232,788 (-)NCBI
SpeTri2.0NW_004936626372,893 - 460,884 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNAL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11869,508,254 - 69,699,628 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1869,510,512 - 69,635,000 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605044,505,410 - 44,707,045 (-)NCBIVero_WHO_p1.0
Gnal
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477019,433,614 - 19,504,759 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system nervous system reproductive system
High
Medium 3
Low 1 3
Below cutoff 1 2 9 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000024927   ⟹   ENSSSCP00000024507
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl697,342,474 - 97,409,032 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000031272   ⟹   ENSSSCP00000026869
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl697,344,896 - 97,429,364 (-)Ensembl
RefSeq Acc Id: XM_003482035   ⟹   XP_003482083
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1697,344,192 - 97,429,334 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021096047   ⟹   XP_020951706
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1697,342,468 - 97,409,053 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021096048   ⟹   XP_020951707
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1697,344,192 - 97,409,069 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003482083 (Get FASTA)   NCBI Sequence Viewer  
  XP_020951706 (Get FASTA)   NCBI Sequence Viewer  
  XP_020951707 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020951706   ⟸   XM_021096047
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003482083   ⟸   XM_003482035
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020951707   ⟸   XM_021096048
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSSCP00000024507   ⟸   ENSSSCT00000024927
RefSeq Acc Id: ENSSSCP00000026869   ⟸   ENSSSCT00000031272


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000022163 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070026587 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000024507 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000026869 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070045149 UniProtKB/TrEMBL
  ENSSSCP00070045150 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000024927 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000031272 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070053288 UniProtKB/TrEMBL
  ENSSSCT00070053289 UniProtKB/TrEMBL
Gene3D-CATH 1.10.400.10 UniProtKB/TrEMBL
InterPro Gprotein_alpha_S UniProtKB/TrEMBL
  Gprotein_alpha_su UniProtKB/TrEMBL
  GproteinA_insert UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report ssc:100736677 UniProtKB/TrEMBL
NCBI Gene GNAL ENTREZGENE
PANTHER PTHR10218 UniProtKB/TrEMBL
Pfam G-alpha UniProtKB/TrEMBL
PRINTS GPROTEINA UniProtKB/TrEMBL
  GPROTEINAS UniProtKB/TrEMBL
PROSITE G_ALPHA UniProtKB/TrEMBL
SMART G_alpha UniProtKB/TrEMBL
Superfamily-SCOP SSF47895 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A4X1VNM1_PIG UniProtKB/TrEMBL
  A0A4X1VSV3_PIG UniProtKB/TrEMBL
  I3LK93_PIG UniProtKB/TrEMBL
  I3LRX8_PIG UniProtKB/TrEMBL
VGNC ID VGNC:88524 ENTREZGENE