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ONTOLOGY REPORT - ANNOTATIONS

Term:ligand-gated monoatomic anion channel activity
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Accession:GO:0099095 term browser browse the term
Definition:Enables the transmembrane transfer of an inorganic anion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
Synonyms:broad_synonym: ligand-gated anion channel activity


show annotations for term's descendants           Sort by:
ligand-gated monoatomic anion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Best3 bestrophin 3 NOT|enables IMP (MGI:7606438|PMID:18414923) UniProt PMID:18414923 MGI:7606438 NCBI chr10:116,822,219...116,865,688
Ensembl chr10:116,822,219...116,860,945 		JBrowse link
G P2rx5 purinergic receptor P2X, ligand-gated ion channel, 5 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:73,029,164...73,063,509
Ensembl chr11:73,051,247...73,063,511 		JBrowse link
extracellularly glutamate-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 enables IDA (PMID:19169251) MGI PMID:19169251 NCBI chr 7:44,813,345...44,825,563
Ensembl chr 7:44,813,373...44,825,566 		JBrowse link
G Slc1a7 solute carrier family 1 (glutamate transporter), member 7 enables IDA (MGI:7294459|PMID:32233906), (MGI:7310191|PMID:16973698) UniProt PMID:16973698 PMID:32233906 MGI:7294459 MGI:7310191 NCBI chr 4:107,825,603...107,870,726
Ensembl chr 4:107,825,529...107,870,729 		JBrowse link
extracellularly glycine-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm5 cholinergic receptor, muscarinic 5 enables TAS (PMID:11756520) MGI PMID:11756520 NCBI chr 2:112,306,055...112,365,487
Ensembl chr 2:112,309,516...112,311,114 		JBrowse link
G Glra1 glycine receptor, alpha 1 subunit enables
contributes_to		 ISO
IMP
IDA		 (PMID:16672662)
(PMID:8062927)
(MGI:5707576|PMID:24801766)		 MGI
RGD
UniProt		 PMID:8062927 PMID:12223345 PMID:16672662 PMID:24801766 GO_REF:0000008 GO_REF:0000096 MGI:4417868 MGI:5707576 RGD:625689 NCBI chr11:55,405,065...55,499,024
Ensembl chr11:55,405,064...55,499,024 		JBrowse link
G Glra2 glycine receptor, alpha 2 subunit enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:163,912,013...164,110,863
Ensembl chr  X:163,912,013...164,110,389 		JBrowse link
G Glra3 glycine receptor, alpha 3 subunit enables ISO MGI
RGD		 PMID:2176214 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:728440 NCBI chr 8:56,393,454...56,583,111
Ensembl chr 8:56,393,495...56,583,105 		JBrowse link
G Glra4 glycine receptor, alpha 4 subunit enables IDA (MGI:5751681|PMID:10762330) UniProt PMID:10762330 MGI:5751681 NCBI chr  X:135,655,107...135,680,935
Ensembl chr  X:135,658,423...135,680,890 		JBrowse link
G Glrb glycine receptor, beta subunit contributes_to
enables		 ISS
IMP
ISO		 (MGI:78784|PMID:8717357)
(PMID:12809985), (PMID:16672662)		 UniProt
MGI		 PMID:8717357 PMID:12809985 PMID:16672662 GO_REF:0000119 MGI:4834177 MGI:78784 NCBI chr 3:80,750,905...80,820,994
Ensembl chr 3:80,750,906...80,820,967 		JBrowse link
GABA-gated chloride ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 contributes_to
enables		 IDA
ISO		 (MGI:6208009|PMID:27129275) UniProt
MGI		 PMID:27129275 GO_REF:0000119 MGI:4834177 MGI:6208009 NCBI chr11:42,021,766...42,073,893
Ensembl chr11:42,021,766...42,073,757 		JBrowse link
G Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 5:71,115,735...71,253,192
Ensembl chr 5:71,114,940...71,253,192 		JBrowse link
G Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr  X:71,476,282...71,700,525
Ensembl chr  X:71,476,287...71,700,454 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 enables IBA GO_Central GO_REF:0000033 NCBI chr 5:71,727,077...71,815,651
Ensembl chr 5:71,727,092...71,815,651 		JBrowse link
G Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 enables IBA GO_Central GO_REF:0000033 NCBI chr 7:57,057,417...57,240,808
Ensembl chr 7:57,057,420...57,159,807 		JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha 6 contributes_to
enables		 ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000096 MGI:4417868 NCBI chr11:42,197,264...42,211,977
Ensembl chr11:42,197,264...42,211,899 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta 1 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:71,815,264...72,306,915
Ensembl chr 5:71,815,456...72,306,380 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 contributes_to IDA
ISO		 (MGI:6208009|PMID:27129275) UniProt
MGI		 PMID:27129275 GO_REF:0000119 MGI:4834177 MGI:6208009 NCBI chr11:42,310,342...42,523,418
Ensembl chr11:42,310,584...42,519,855 		JBrowse link
G Gabrb3 GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3 contributes_to
enables		 IDA
IMP
ISO		 (MGI:6208009|PMID:27129275)
(MGI:87150|PMID:9108119)		 UniProt
MGI		 PMID:9108119 PMID:27129275 GO_REF:0000119 MGI:4834177 MGI:6208009 MGI:87150 NCBI chr 7:57,240,266...57,478,550
Ensembl chr 7:57,069,440...57,478,550 		JBrowse link
G Gabre gamma-aminobutyric acid (GABA) A receptor, subunit epsilon enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr  X:71,300,532...71,318,433
Ensembl chr  X:71,299,605...71,318,409 		JBrowse link
G Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 enables IBA GO_Central GO_REF:0000033 NCBI chr 5:70,906,512...70,999,960
Ensembl chr 5:70,908,390...70,999,960 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor, subunit gamma 2 contributes_to
enables		 IDA
ISO		 (MGI:6208009|PMID:27129275) UniProt
MGI		 PMID:27129275 GO_REF:0000119 MGI:4834177 MGI:6208009 NCBI chr11:41,801,017...41,891,684
Ensembl chr11:41,801,030...41,891,684 		JBrowse link
G Gabrg3 gamma-aminobutyric acid type A receptor, subunit gamma 3 enables IBA GO_Central GO_REF:0000033 NCBI chr 7:56,366,211...57,037,173
Ensembl chr 7:56,366,213...57,036,936 		JBrowse link
G Gabrp gamma-aminobutyric acid type A receptor subunit pi enables ISO (PMID:10462548)
PMID:17003036		 UniProt PMID:10462548 PMID:17003036 RGD:405650305 NCBI chr11:33,500,781...33,528,978
Ensembl chr11:33,500,781...33,528,959 		JBrowse link
G Gabrq gamma-aminobutyric acid type A receptor subunit theta enables ISO (PMID:16412217) UniProt PMID:16412217 NCBI chr  X:71,868,769...71,886,213
Ensembl chr  X:71,868,784...71,886,208 		JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 enables ISO PMID:8524843 UniProt PMID:8524843 RGD:728796 NCBI chr 4:33,132,556...33,163,606
Ensembl chr 4:33,132,521...33,163,588 		JBrowse link
G Gabrr2 gamma-aminobutyric acid type A receptor subunit rho 2 enables ISO PMID:8524843 UniProt PMID:8524843 RGD:728796 NCBI chr 4:33,057,715...33,095,865
Ensembl chr 4:33,062,999...33,095,865 		JBrowse link
G Gabrr3 gamma-aminobutyric acid type A receptor subunit rho 3 enables ISO PMID:11861315 UniProt PMID:11861315 RGD:405650323 NCBI chr16:59,227,745...59,282,102
Ensembl chr16:59,227,695...59,284,867 		JBrowse link
glycine-gated chloride ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glra2 glycine receptor, alpha 2 subunit enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:163,912,013...164,110,863
Ensembl chr  X:163,912,013...164,110,389 		JBrowse link
G Glra3 glycine receptor, alpha 3 subunit enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:56,393,454...56,583,111
Ensembl chr 8:56,393,495...56,583,105 		JBrowse link
intracellularly ATP-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr cystic fibrosis transmembrane conductance regulator enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
intracellularly calcium-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ano1 anoctamin 1, calcium activated chloride channel enables ISO
IBA
IDA		 (MGI:3815244|PMID:18724360), (MGI:5448512|PMID:22075693), (MGI:5461590|PMID:22634729), (MGI:6316357|PMID:28561733), (PMID:20056604), (PMID:23532839), (PMID:23576756) MGI
GO_Central
RGD		 PMID:18724360 PMID:20056604 PMID:20421283 PMID:22075693 PMID:22634729 More... GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:3815244 MGI:4417868 MGI:4834177 MGI:5448512 MGI:5461590 MGI:6316357 RGD:9684846 RGD:9684847 NCBI chr 7:144,142,286...144,305,762
Ensembl chr 7:144,142,286...144,305,711 		JBrowse link
G Ano10 anoctamin 10 enables
NOT|enables		 ISO
IDA		 (PMID:22946059)
(PMID:23532839)		 UniProt
MGI		 PMID:22946059 PMID:23532839 NCBI chr 9:122,004,958...122,123,440
Ensembl chr 9:122,004,940...122,123,489 		JBrowse link
G Ano2 anoctamin 2 enables ISO
IMP
IDA
IBA		 (PMID:21516098)
(MGI:3848635|PMID:19474308), (MGI:4412429|PMID:19561302), (MGI:4413547|PMID:19475416), (MGI:5448512|PMID:22075693), (PMID:20056604), (PMID:23532839)		 MGI
UniProt
GO_Central
RGD		 PMID:19474308 PMID:19475416 PMID:19561302 PMID:20056604 PMID:21516098 More... GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:3848635 MGI:4412429 MGI:4413547 MGI:4417868 MGI:4834177 MGI:5448512 RGD:9684847 NCBI chr 6:125,667,382...126,017,115
Ensembl chr 6:125,667,382...126,017,089 		JBrowse link
G Ano3 anoctamin 3 NOT|enables IDA (PMID:23532839) MGI PMID:23532839 NCBI chr 2:110,485,546...110,780,854
Ensembl chr 2:110,485,546...110,781,268 		JBrowse link
G Ano4 anoctamin 4 enables
NOT|enables		 ISO
IDA		 (PMID:22946059)
(MGI:5448512|PMID:22075693), (PMID:23532839)		 UniProt
MGI		 PMID:22075693 PMID:22946059 PMID:23532839 MGI:5448512 NCBI chr10:88,784,794...89,181,059
Ensembl chr10:88,784,856...89,180,624 		JBrowse link
G Ano5 anoctamin 5 enables
NOT|enables		 ISO
IDA		 (PMID:22946059)
(PMID:23532839)		 UniProt
MGI		 PMID:22946059 PMID:23532839 NCBI chr 7:51,160,668...51,248,459
Ensembl chr 7:51,160,777...51,248,457 		JBrowse link
G Ano6 anoctamin 6 enables
NOT|enables		 IDA
IMP		 (MGI:6316485|PMID:30785399), (PMID:20056604)
(PMID:23159814)
(MGI:5448512|PMID:22075693), (PMID:23532839)		 UniProt
MGI		 PMID:20056604 PMID:22075693 PMID:23159814 PMID:23532839 PMID:30785399 MGI:5448512 MGI:6316485 NCBI chr15:95,688,724...95,873,353
Ensembl chr15:95,688,724...95,872,632 		JBrowse link
G Ano7 anoctamin 7 NOT|enables IDA
ISO		 (PMID:23532839)
(PMID:22946059)		 MGI
UniProt		 PMID:22946059 PMID:23532839 NCBI chr 1:93,301,518...93,332,026
Ensembl chr 1:93,301,652...93,332,025 		JBrowse link
G Ano8 anoctamin 8 enables
NOT|enables		 ISO
IDA		 (PMID:22946059)
(PMID:23532839)		 UniProt
MGI		 PMID:22946059 PMID:23532839 NCBI chr 8:71,928,660...71,938,735
Ensembl chr 8:71,928,663...71,938,607 		JBrowse link
G Ano9 anoctamin 9 enables
NOT|enables		 ISO
IDA		 (PMID:22946059)
(PMID:23532839)		 UniProt
MGI		 PMID:22946059 PMID:23532839 NCBI chr 7:140,681,125...140,697,719
Ensembl chr 7:140,681,125...140,697,719 		JBrowse link
G Best1 bestrophin 1 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:9,962,536...9,978,997
Ensembl chr19:9,962,538...9,978,997 		JBrowse link
G Best3 bestrophin 3 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:116,822,219...116,865,688
Ensembl chr10:116,822,219...116,860,945 		JBrowse link
G Clca1 chloride channel accessory 1 enables IBA GO_Central GO_REF:0000033 NCBI chr 3:144,710,298...144,738,537
Ensembl chr 3:144,709,578...144,738,537 		JBrowse link
G Clca2 chloride channel accessory 2 enables IBA GO_Central GO_REF:0000033 NCBI chr 3:144,776,021...144,805,204
Ensembl chr 3:144,776,024...144,805,204 		JBrowse link
G Clca3a1 chloride channel accessory 3A1 enables IBA
IDA		 (PMID:9822685) GO_Central
MGI		 PMID:9822685 GO_REF:0000033 NCBI chr 3:144,435,438...144,466,738
Ensembl chr 3:144,435,438...144,466,738 		JBrowse link
G Clca3a2 chloride channel accessory 3A2 enables ISA
IBA		 (PMID:11483609) MGI
GO_Central		 PMID:11483609 GO_REF:0000033 NCBI chr 3:144,486,340...144,525,385
Ensembl chr 3:144,502,320...144,525,255 		JBrowse link
G Clca3b chloride channel accessory 3B enables IBA GO_Central GO_REF:0000033 NCBI chr 3:144,528,384...144,555,063
Ensembl chr 3:144,528,384...144,555,118 		JBrowse link
G Clca4a chloride channel accessory 4A enables IBA GO_Central GO_REF:0000033 NCBI chr 3:144,658,247...144,680,806
Ensembl chr 3:144,658,241...144,680,806 		JBrowse link
G Clca4b chloride channel accessory 4B enables IBA GO_Central GO_REF:0000033 NCBI chr 3:144,616,682...144,638,290
Ensembl chr 3:144,616,682...144,638,290 		JBrowse link
G Clns1a chloride channel, nucleotide-sensitive, 1A enables ISO (PMID:15905169) CAFA PMID:15905169 NCBI chr 7:97,345,864...97,370,000
Ensembl chr 7:97,345,841...97,370,003 		JBrowse link
G Nmur2 neuromedin U receptor 2 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:55,915,816...55,931,813
Ensembl chr11:55,915,813...55,931,836 		JBrowse link
G Ttyh1 tweety family member 1 enables IBA GO_Central GO_REF:0000033 NCBI chr 7:4,122,418...4,139,206
Ensembl chr 7:4,122,407...4,139,707 		JBrowse link
G Ttyh2 tweety family member 2 enables IBA GO_Central GO_REF:0000033 NCBI chr11:114,566,294...114,611,810
Ensembl chr11:114,566,257...114,611,803 		JBrowse link
G Ttyh3 tweety family member 3 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 5:140,606,332...140,634,826
Ensembl chr 5:140,606,333...140,634,786 		JBrowse link
pH-gated chloride channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pacc1 proton activated chloride channel 1 enables IMP
ISO		 (MGI:6294694|PMID:31023925) UniProt
MGI		 PMID:31023925 GO_REF:0000119 MGI:4834177 MGI:6294694 NCBI chr 1:191,058,099...191,083,481
Ensembl chr 1:191,058,109...191,083,111 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 28831
    transporter activity 1198
      transmembrane transporter activity 1108
        monoatomic ion transmembrane transporter activity 733
          monoatomic ion channel activity 445
            monoatomic anion channel activity 103
              ligand-gated monoatomic anion channel activity 53
                GABA-gated chloride ion channel activity 18
                extracellularly glutamate-gated chloride channel activity 2
                extracellularly glycine-gated chloride channel activity 6
                glycine-gated chloride ion channel activity 2
                intracellularly ATP-gated chloride channel activity 1
                intracellularly calcium-gated chloride channel activity 24
                pH-gated chloride channel activity 1
                serotonin-gated chloride channel activity 0
Path 2
Term Annotations click to browse term
  molecular_function 28831
    transporter activity 1198
      transmembrane transporter activity 1108
        passive transmembrane transporter activity 513
          channel activity 513
            gated channel activity 323
              ligand-gated channel activity 188
                ligand-gated monoatomic ion channel activity 184
                  ligand-gated monoatomic anion channel activity 53
                    GABA-gated chloride ion channel activity 18
                    extracellularly glutamate-gated chloride channel activity 2
                    extracellularly glycine-gated chloride channel activity 6
                    glycine-gated chloride ion channel activity 2
                    intracellularly ATP-gated chloride channel activity 1
                    intracellularly calcium-gated chloride channel activity 24
                    pH-gated chloride channel activity 1
                    serotonin-gated chloride channel activity 0
paths to the root