Glrb (glycine receptor, beta subunit) - Rat Genome Database

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Gene: Glrb (glycine receptor, beta subunit) Mus musculus
Analyze
Symbol: Glrb
Name: glycine receptor, beta subunit
RGD ID: 10657
MGI Page MGI
Description: Enables extracellularly glycine-gated chloride channel activity; glycine binding activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Acts upstream of or within several processes, including adult walking behavior; gamma-aminobutyric acid receptor clustering; and righting reflex. Located in GABA-ergic synapse; dendrite; and membrane. Is active in glycinergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skeleton. Used to study hyperekplexia 2. Human ortholog(s) of this gene implicated in hyperekplexia 2. Orthologous to human GLRB (glycine receptor beta).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AI853901; glycine receptor 58 kDa subunit; glycine receptor subunit beta; Glyrb; inhibitory glycine receptor; spa; spastic
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39380,750,905 - 80,820,994 (-)NCBIGRCm39mm39
GRCm39 Ensembl380,750,906 - 80,820,967 (-)Ensembl
GRCm38380,843,598 - 80,913,660 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl380,843,599 - 80,913,660 (-)EnsemblGRCm38mm10GRCm38
MGSCv37380,647,526 - 80,717,546 (-)NCBIGRCm37mm9NCBIm37
MGSCv36380,929,531 - 80,999,551 (-)NCBImm8
Celera380,847,975 - 80,918,248 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map335.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The activation mechanism of alpha1 homomeric glycine receptors. Beato M, etal., J Neurosci. 2004 Jan 28;24(4):895-906.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Mouse MP Annotation Import Pipeline RGD automated import pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:489953   PMID:849243   PMID:1338094   PMID:1371219   PMID:2983837   PMID:4323808   PMID:4557539   PMID:4870412   PMID:6285205   PMID:7626896   PMID:7891186   PMID:7920630  
PMID:7946325   PMID:8088953   PMID:8168656   PMID:8298642   PMID:8635460   PMID:8717357   PMID:8733750   PMID:8889548   PMID:9051263   PMID:9087981   PMID:9425524   PMID:9430649  
PMID:10349636   PMID:10651857   PMID:11042159   PMID:11076688   PMID:11076861   PMID:11168555   PMID:11217851   PMID:11256962   PMID:12056449   PMID:12477932   PMID:12809985   PMID:12837931  
PMID:13877851   PMID:14681479   PMID:16141072   PMID:16141073   PMID:16182553   PMID:16602821   PMID:16672662   PMID:17145751   PMID:17308032   PMID:17347650   PMID:18287559   PMID:18425804  
PMID:18445051   PMID:18721822   PMID:18854036   PMID:19723286   PMID:20600650   PMID:21135047   PMID:21486797   PMID:21829170   PMID:21850450   PMID:21873635   PMID:22723691   PMID:22782896  
PMID:22937132   PMID:23118727   PMID:23359859   PMID:24154525   PMID:24509844   PMID:24952961   PMID:25955356   PMID:32581705   PMID:32848605   PMID:34878402   PMID:35108108  


Genomics

Comparative Map Data
Glrb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39380,750,905 - 80,820,994 (-)NCBIGRCm39mm39
GRCm39 Ensembl380,750,906 - 80,820,967 (-)Ensembl
GRCm38380,843,598 - 80,913,660 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl380,843,599 - 80,913,660 (-)EnsemblGRCm38mm10GRCm38
MGSCv37380,647,526 - 80,717,546 (-)NCBIGRCm37mm9NCBIm37
MGSCv36380,929,531 - 80,999,551 (-)NCBImm8
Celera380,847,975 - 80,918,248 (-)NCBICelera
Cytogenetic Map3E3NCBI
cM Map335.71NCBI
GLRB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384157,076,150 - 157,172,090 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl4157,076,125 - 157,172,090 (+)EnsemblGRCh38hg38GRCh38
GRCh374157,997,302 - 158,093,242 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364158,216,788 - 158,312,304 (+)NCBINCBI36hg18NCBI36
Build 344158,354,942 - 158,450,454NCBI
Celera4155,340,138 - 155,436,102 (+)NCBI
Cytogenetic Map4q32.1NCBI
HuRef4153,748,311 - 153,844,227 (+)NCBIHuRef
CHM1_14157,974,414 - 158,070,403 (+)NCBICHM1_1
T2T-CHM13v2.04160,421,647 - 160,517,588 (+)NCBI
Glrb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22166,134,624 - 166,207,509 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2166,134,626 - 166,207,489 (-)Ensembl
Rnor_6.02179,768,040 - 179,842,612 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2179,769,009 - 179,842,547 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02199,176,881 - 199,251,847 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42172,451,807 - 172,522,841 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12172,401,912 - 172,472,947 (-)NCBI
Celera2160,176,470 - 160,246,571 (-)NCBICelera
Cytogenetic Map2q33NCBI
Glrb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547110,152,156 - 10,238,832 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547110,153,197 - 10,238,052 (-)NCBIChiLan1.0ChiLan1.0
GLRB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14161,237,189 - 161,333,035 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4161,236,610 - 161,333,035 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04149,422,654 - 149,518,669 (+)NCBIMhudiblu_PPA_v0panPan3
GLRB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11554,429,131 - 54,519,844 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1554,429,765 - 54,518,456 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1554,768,588 - 54,860,188 (+)NCBI
ROS_Cfam_1.01555,148,897 - 55,240,783 (+)NCBI
ROS_Cfam_1.0 Ensembl1555,148,838 - 55,241,494 (+)Ensembl
UMICH_Zoey_3.11554,388,996 - 54,480,800 (+)NCBI
UNSW_CanFamBas_1.01554,497,373 - 54,589,168 (+)NCBI
UU_Cfam_GSD_1.01554,812,663 - 54,904,694 (+)NCBI
Glrb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530135,794,322 - 35,881,762 (-)NCBI
SpeTri2.0NW_0049365763,665,128 - 3,752,592 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLRB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl845,912,938 - 46,034,448 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1845,912,869 - 46,034,455 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2848,009,454 - 48,070,932 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GLRB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17103,669,663 - 103,760,005 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl7103,669,616 - 103,760,531 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603783,270,028 - 83,444,133 (+)NCBIVero_WHO_p1.0
Glrb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248481,298,174 - 1,384,513 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248481,301,051 - 1,383,931 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
AF016099  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38380,861,731 - 80,861,834UniSTSGRCm38
MGSCv37380,665,653 - 80,665,756UniSTSGRCm37
Celera380,866,007 - 80,866,110UniSTS
Cytogenetic Map3E3-F1UniSTS
Whitehead/MRC_RH3772.94UniSTS
Glrb  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3E3-F1UniSTS
cM Map336.0UniSTS
AI853901  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38380,843,804 - 80,843,888UniSTSGRCm38
MGSCv37380,647,726 - 80,647,810UniSTSGRCm37
Celera380,848,175 - 80,848,259UniSTS
Cytogenetic Map3E3-F1UniSTS
Whitehead/MRC_RH3772.94UniSTS
Glrb  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3E3-F1UniSTS
cM Map336.0UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1024922183184946Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1024922183184946Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1024922183184946Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31024922183184946Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31024922183184946Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31024922183184946Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
4141079Ath23_matherosclerosis 23 (mouse)Not determined4935758183357581Mouse
1300895Hdl5_mHDL level 5 (mouse)Not determined34949500583495118Mouse
1301824Susp_msuppressor of superoxide production (mouse)Not determined34949500583495118Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
1357585Manln3_mmandible length 3 (mouse)Not determined35262550986625745Mouse
1301917Tshp4_mtooth shape 4 (mouse)Not determined35262550986625745Mouse
1300593Skull4_mskull morphology 4 (mouse)Not determined35262550986625745Mouse
13464139Nhdlq17_mnon-HDL QTL 17 (mouse)35292318386923183Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35890730792907307Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36174006195740241Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366046658100046795Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369568554103568554Mouse
1301791Char4_mP. chabaudi malaria resistance QTL 4 (mouse)Not determined369625509100655290Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370208904104209042Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1411
Count of miRNA genes:588
Interacting mature miRNAs:712
Transcripts:ENSMUST00000029654, ENSMUST00000107743, ENSMUST00000132330, ENSMUST00000135043
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001281969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001345955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001345956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001345957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001345958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001345959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001345996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162898 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036162901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF016099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ300577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK082578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AM420316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV355005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB856907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L32593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L32594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U09399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X81201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X81202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X81203 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X81204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000029654   ⟹   ENSMUSP00000029654
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl380,750,906 - 80,820,967 (-)Ensembl
GRCm38.p6 Ensembl380,843,599 - 80,913,660 (-)Ensembl
RefSeq Acc Id: ENSMUST00000107743   ⟹   ENSMUSP00000103372
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl380,762,936 - 80,820,835 (-)Ensembl
GRCm38.p6 Ensembl380,855,629 - 80,913,528 (-)Ensembl
RefSeq Acc Id: ENSMUST00000132330   ⟹   ENSMUSP00000115014
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl380,769,417 - 80,820,896 (-)Ensembl
GRCm38.p6 Ensembl380,862,110 - 80,913,589 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135043   ⟹   ENSMUSP00000116604
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl380,750,906 - 80,820,921 (-)Ensembl
GRCm38.p6 Ensembl380,843,599 - 80,913,614 (-)Ensembl
RefSeq Acc Id: ENSMUST00000193031
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl380,762,943 - 80,764,562 (-)Ensembl
GRCm38.p6 Ensembl380,855,636 - 80,857,255 (-)Ensembl
RefSeq Acc Id: ENSMUST00000194085   ⟹   ENSMUSP00000142306
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl380,752,268 - 80,819,396 (-)Ensembl
GRCm38.p6 Ensembl380,844,961 - 80,912,089 (-)Ensembl
RefSeq Acc Id: NM_001281969   ⟹   NP_001268898
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,906 - 80,820,967 (-)NCBI
GRCm38380,843,599 - 80,913,660 (-)NCBI
Celera380,847,970 - 80,918,284 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001345955   ⟹   NP_001332884
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,906 - 80,820,967 (-)NCBI
GRCm38380,843,599 - 80,913,660 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001345956   ⟹   NP_001332885
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,906 - 80,820,967 (-)NCBI
GRCm38380,843,599 - 80,913,660 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001345957   ⟹   NP_001332886
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,906 - 80,820,967 (-)NCBI
GRCm38380,843,599 - 80,913,660 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001345958   ⟹   NP_001332887
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,906 - 80,820,967 (-)NCBI
GRCm38380,843,599 - 80,913,660 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001345959   ⟹   NP_001332888
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,906 - 80,820,967 (-)NCBI
GRCm38380,843,599 - 80,913,660 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001345996   ⟹   NP_001332925
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,906 - 80,819,425 (-)NCBI
GRCm38380,843,599 - 80,912,118 (-)NCBI
Sequence:
RefSeq Acc Id: NM_010298   ⟹   NP_034428
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,906 - 80,820,967 (-)NCBI
GRCm38380,843,599 - 80,913,660 (-)NCBI
MGSCv37380,647,526 - 80,717,546 (-)RGD
Celera380,847,970 - 80,918,284 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030252428   ⟹   XP_030108288
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,905 - 80,820,994 (-)NCBI
GRCm38380,843,598 - 80,913,660 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162898   ⟹   XP_036018791
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,905 - 80,820,972 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162899   ⟹   XP_036018792
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,983 - 80,820,972 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162900   ⟹   XP_036018793
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,905 - 80,820,972 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036162901   ⟹   XP_036018794
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39380,750,905 - 80,820,918 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034428   ⟸   NM_010298
- Peptide Label: isoform 4 precursor
- UniProtKB: P48168 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001268898   ⟸   NM_001281969
- Peptide Label: isoform 7
- UniProtKB: P48168 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_030108288   ⟸   XM_030252428
- Peptide Label: isoform X5
RefSeq Acc Id: NP_001332887   ⟸   NM_001345958
- Peptide Label: isoform 6
- UniProtKB: P48168 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001332886   ⟸   NM_001345957
- Peptide Label: isoform 3 precursor
- UniProtKB: P48168 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001332885   ⟸   NM_001345956
- Peptide Label: isoform 2 precursor
- UniProtKB: P48168 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001332884   ⟸   NM_001345955
- Peptide Label: isoform 1 precursor
- UniProtKB: P48168 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001332888   ⟸   NM_001345959
- Peptide Label: isoform 7
- UniProtKB: P48168 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001332925   ⟸   NM_001345996
- Peptide Label: isoform 5 precursor
- UniProtKB: P48168 (UniProtKB/Swiss-Prot),   A1KR23 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000029654   ⟸   ENSMUST00000029654
RefSeq Acc Id: ENSMUSP00000103372   ⟸   ENSMUST00000107743
RefSeq Acc Id: ENSMUSP00000115014   ⟸   ENSMUST00000132330
RefSeq Acc Id: ENSMUSP00000116604   ⟸   ENSMUST00000135043
RefSeq Acc Id: ENSMUSP00000142306   ⟸   ENSMUST00000194085
RefSeq Acc Id: XP_036018793   ⟸   XM_036162900
- Peptide Label: isoform X3
RefSeq Acc Id: XP_036018791   ⟸   XM_036162898
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036018794   ⟸   XM_036162901
- Peptide Label: isoform X4
RefSeq Acc Id: XP_036018792   ⟸   XM_036162899
- Peptide Label: isoform X2
Protein Domains
Neur_chan_LBD   Neur_chan_memb

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P48168-F1-model_v2 AlphaFold P48168 1-496 view protein structure

Promoters
RGD ID:6833830
Promoter ID:MM_KWN:34659
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   Brain
Transcripts:ENSMUST00000107743,   OTTMUST00000059853,   OTTMUST00000059854,   UC008POH.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36380,717,394 - 80,717,894 (-)MPROMDB
RGD ID:6880942
Promoter ID:EPDNEW_M3922
Type:single initiation site
Name:Glrb_2
Description:Mus musculus glycine receptor, beta subunit , transcript variant5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3923  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38380,888,147 - 80,888,207EPDNEW
RGD ID:6880944
Promoter ID:EPDNEW_M3923
Type:initiation region
Name:Glrb_1
Description:Mus musculus glycine receptor, beta subunit , transcript variant5, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M3922  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38380,913,644 - 80,913,704EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95751 AgrOrtholog
Ensembl Genes ENSMUSG00000028020 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000029654 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000103372.2 UniProtKB/TrEMBL
  ENSMUSP00000115014.2 UniProtKB/TrEMBL
  ENSMUSP00000116604.2 UniProtKB/TrEMBL
  ENSMUSP00000142306 ENTREZGENE
  ENSMUSP00000142306.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000029654 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000107743.8 UniProtKB/TrEMBL
  ENSMUST00000132330.2 UniProtKB/TrEMBL
  ENSMUST00000135043.8 UniProtKB/TrEMBL
  ENSMUST00000194085 ENTREZGENE
  ENSMUST00000194085.6 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Glycine_rcpt_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_channel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14658 UniProtKB/Swiss-Prot
MGD MGI:95751 ENTREZGENE
NCBI Gene 14658 ENTREZGENE
PANTHER PTHR18945 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18945:SF29 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Glrb PhenoGen
PRINTS GLYRBETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs LIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A1KR23 ENTREZGENE, UniProtKB/TrEMBL
  E9PV81_MOUSE UniProtKB/TrEMBL
  E9Q3E3_MOUSE UniProtKB/TrEMBL
  E9Q9K1_MOUSE UniProtKB/TrEMBL
  GLRB_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q5U5X3 UniProtKB/Swiss-Prot