Gabrg2 (gamma-aminobutyric acid type A receptor, subunit gamma 2) - Rat Genome Database

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Gene: Gabrg2 (gamma-aminobutyric acid type A receptor, subunit gamma 2) Mus musculus
Analyze
Symbol: Gabrg2
Name: gamma-aminobutyric acid type A receptor, subunit gamma 2 (Ensembl:gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2)
RGD ID: 62259
MGI Page MGI
Description: Enables GABA-A receptor activity; chloride channel activity; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Contributes to GABA-gated chloride ion channel activity. Involved in cellular response to histamine; chloride transmembrane transport; and inhibitory synapse assembly. Acts upstream of or within several processes, including chemical postsynaptic transmission; gamma-aminobutyric acid signaling pathway; and regulation of postsynaptic membrane potential. Located in axon and plasma membrane. Part of GABA-A receptor complex. Is active in GABA-ergic synapse. Is expressed in central nervous system; eye; palatal shelf; and peripheral nervous system ganglion. Used to study generalized epilepsy with febrile seizures plus. Human ortholog(s) of this gene implicated in childhood absence epilepsy; developmental and epileptic encephalopathy 74; and familial febrile seizures 8. Orthologous to human GABRG2 (gamma-aminobutyric acid type A receptor subunit gamma2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI851231; BB128510; GAB; GABA(A) receptor subunit gamma-2; GABAA-R; Gabrg; Gabrg-2; gamm; gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2; gamma-aminobutyric acid receptor subunit gamma-2; GAMMA-AMINOBUTYRIC-ACID RECEPTOR GAMMA-2 SUBUNIT PRECURSOR (GABA(A) RECEPTOR); gamma2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391141,801,017 - 41,891,684 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1141,801,030 - 41,891,684 (-)EnsemblGRCm39 Ensembl
GRCm381141,910,190 - 42,000,857 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1141,910,203 - 42,000,857 (-)EnsemblGRCm38mm10GRCm38
MGSCv371141,723,697 - 41,814,180 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361141,753,618 - 41,844,101 (-)NCBIMGSCv36mm8
Celera1145,722,009 - 45,812,211 (-)NCBICelera
Cytogenetic Map11A5NCBI
cM Map1124.8NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-beta-thujone  (ISO)
(+)-isoborneol  (ISO)
(+)-pilocarpine  (EXP)
(R)-camphor  (ISO)
(S)-nicotine  (EXP)
1,2-dichloroethane  (EXP)
1-(2-methoxyphenyl)piperazine  (ISO)
1-(3-(trifluoromethyl)phenyl)piperazine  (ISO)
1-(3-chlorophenyl)piperazine  (ISO)
1-benzylpiperazine  (ISO)
1-bromopropane  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-tetrachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,6-Dimethylphenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-Methylenedioxyamphetamine  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3alpha-hydroxy-5beta-pregnan-20-one  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4-ethyl-4-methylpiperidine-2,6-dione  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
alpha-hexachlorocyclohexane  (ISO)
Alphaxolone  (ISO)
amphetamine  (ISO)
anthracenes  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzodiazepine  (EXP)
bicuculline  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
bromoform  (ISO)
butan-1-ol  (ISO)
cadmium dichloride  (ISO)
camphor  (ISO)
carisoprodol  (ISO)
carvone  (ISO)
CGP 52608  (ISO)
cocaine  (EXP,ISO)
cypermethrin  (EXP)
delta-hexachlorocyclohexane  (ISO)
dexamethasone  (ISO)
diazepam  (EXP,ISO)
dieldrin  (ISO)
dorsomorphin  (ISO)
ethanol  (EXP,ISO)
Etizolam  (ISO)
etomidate  (ISO)
famotidine  (ISO)
felbamate  (ISO)
fenvalerate  (ISO)
fipronil  (ISO)
flumazenil  (ISO)
flunitrazepam  (ISO)
flurotyl  (ISO)
flutamide  (ISO)
fulvestrant  (ISO)
gamma-aminobutyric acid  (EXP,ISO)
gamma-hexachlorocyclohexane  (ISO)
hexobarbital  (ISO)
ketamine  (ISO)
lanthanum atom  (ISO)
lead(0)  (ISO)
levonorgestrel  (ISO)
lipopolysaccharide  (ISO)
Lorazepam  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menthone  (ISO)
methamphetamine  (ISO)
methylmercury chloride  (ISO)
Methylone  (ISO)
midazolam  (EXP)
morphine  (EXP)
muscimol  (ISO)
nicotine  (EXP)
Niflumic acid  (ISO)
o-cresol  (ISO)
p-menthan-3-ol  (ISO)
pentetrazol  (ISO)
pentobarbital  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctanoic acid  (ISO)
picrotoxin  (ISO)
picrotoxinin  (ISO)
poly(I:C)  (ISO)
pregnenolone sulfate  (ISO)
propofol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sevoflurane  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
tert-Butylbicyclophosphorothionate  (ISO)
Testosterone propionate  (EXP)
theophylline  (EXP)
thymol  (ISO)
thymol sulfate(1-)  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
topiramate  (ISO)
trichostatin A  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
zaleplon  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zolpidem  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal brain wave pattern  (IAGP)
abnormal GABA-mediated receptor currents  (IAGP)
abnormal gait  (IAGP)
abnormal inhibitory postsynaptic currents  (IAGP)
abnormal miniature inhibitory postsynaptic currents  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal neuron physiology  (IAGP)
abnormal ovary morphology  (IEA)
abnormal skin morphology  (IEA)
abnormal spatial reference memory  (IAGP)
abnormal spike wave discharge  (IAGP)
abnormal synapse morphology  (IAGP)
abnormal testis morphology  (IEA)
abnormal xenobiotic pharmacokinetics  (IAGP)
absence seizures  (IAGP)
decreased bone mineral density  (IEA)
decreased heart weight  (IEA)
decreased locomotor activity  (IAGP)
decreased physiological sensitivity to xenobiotic  (IAGP)
decreased susceptibility to pharmacologically induced seizures  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
enhanced behavioral response to xenobiotic  (IAGP)
enlarged testis  (IEA)
febrile seizures  (IAGP)
hunched posture  (IAGP)
hyperactivity  (IAGP)
impaired behavioral response to xenobiotic  (IAGP)
impaired coordination  (IAGP)
impaired righting response  (IAGP)
increased anxiety-related response  (IAGP)
increased locomotor activity  (IAGP)
increased susceptibility to pharmacologically induced seizures  (IAGP)
increased vertical activity  (IAGP)
lethality at weaning, complete penetrance  (IAGP)
limb grasping  (IAGP)
myoclonus  (IAGP)
no abnormal phenotype detected  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
persistence of hyaloid vascular system  (IEA)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IEA)
reduced male fertility  (IAGP)
seizures  (IAGP)
sudden unexpected death in epilepsy  (IAGP)
tonic-clonic seizures  (IAGP)
tremors  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Downregulation of Gabra4 expression during alcohol withdrawal is mediated by specific microRNAs in cultured mouse cortical neurons. Bekdash RA and Harrison NL, Brain Behav. 2015 Aug;5(8):e00355. doi: 10.1002/brb3.355. Epub 2015 Jun 2.
2. Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors. Cagetti E, etal., Mol Pharmacol. 2003 Jan;63(1):53-64. doi: 10.1124/mol.63.1.53.
3. GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats. Enoch MA, etal., PLoS One. 2012;7(1):e29369. doi: 10.1371/journal.pone.0029369. Epub 2012 Jan 13.
4. A splice-site mutation in GABRG2 associated with childhood absence epilepsy and febrile convulsions. Kananura C, etal., Arch Neurol 2002 Jul;59(7):1137-41.
5. Polymorphism in cytochrome P450 2E1 and interaction with other genetic risk factors and susceptibility to alcoholic liver cirrhosis. Khan AJ, etal., Mutat Res. 2009 May 12;664(1-2):55-63. doi: 10.1016/j.mrfmmm.2009.02.009. Epub 2009 Feb 28.
6. Expression of gamma-aminobutyric acid A receptor subunits alpha1, beta1, gamma2 mRNA in rats with hepatic encephalopathy. Li XQ, etal., World J Gastroenterol. 2005 Jun 7;11(21):3319-22.
7. Mechanisms of reversible GABAA receptor plasticity after ethanol intoxication. Liang J, etal., J Neurosci. 2007 Nov 7;27(45):12367-77. doi: 10.1523/JNEUROSCI.2786-07.2007.
8. Examining the effects of alcohol on GABAA receptor mRNA expression and function in neural cultures generated from control and alcohol dependent donor induced pluripotent stem cells. Lieberman R, etal., Alcohol. 2018 Feb;66:45-53. doi: 10.1016/j.alcohol.2017.08.005. Epub 2017 Aug 12.
9. Gender-specific contribution of the GABA(A) subunit genes on 5q33 in methamphetamine use disorder. Lin SK, etal., Pharmacogenomics J. 2003;3(6):349-55. doi: 10.1038/sj.tpj.6500203.
10. Association analysis of GABA receptor subunit genes on 5q33 with heroin dependence in a Chinese male population. Loh EW, etal., Am J Med Genet B Neuropsychiatr Genet. 2007 Jun 5;144B(4):439-43. doi: 10.1002/ajmg.b.30429.
11. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
12. MGDs mouse GO annotations MGD data from the GO Consortium
13. MGD IEA MGD IEA
14. Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus. Nuñez JL and McCarthy MM, Exp Neurol. 2008 Apr;210(2):699-708. doi: 10.1016/j.expneurol.2008.01.001. Epub 2008 Jan 19.
15. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
16. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
17. Altered gabaa receptor subunit and splice variant expression in rats treated with chronic intermittent ethanol. Petrie J, etal., Alcohol Clin Exp Res. 2001 Jun;25(6):819-28.
18. Haplotype-based localization of an alcohol dependence gene to the 5q34 {gamma}-aminobutyric acid type A gene cluster. Radel M, etal., Arch Gen Psychiatry. 2005 Jan;62(1):47-55. doi: 10.1001/archpsyc.62.1.47.
19. Mouse MP Annotation Import Pipeline RGD automated import pipeline
20. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
22. Two novel GABAA receptor subunits exist in distinct neuronal subpopulations. Shivers BD, etal., Neuron 1989 Sep;3(3):327-37.
23. Perinatal alcohol exposure leads to prolonged upregulation of hypothalamic GABA A receptors and increases behavioral sensitivity to gaboxadol. Volgin DV, Neurosci Lett. 2008 Jul 11;439(2):182-6. doi: 10.1016/j.neulet.2008.05.011. Epub 2008 May 8.
Additional References at PubMed
PMID:1315307   PMID:1321150   PMID:1358285   PMID:1359369   PMID:1661635   PMID:1702226   PMID:1846404   PMID:2788176   PMID:7560270   PMID:7643102   PMID:7644489   PMID:8395631  
PMID:8595891   PMID:8613747   PMID:8665663   PMID:8717335   PMID:8889548   PMID:9070927   PMID:9507960   PMID:9682826   PMID:9880662   PMID:10196563   PMID:10218866   PMID:10349636  
PMID:10461223   PMID:10531433   PMID:10536013   PMID:10880692   PMID:10900017   PMID:10944167   PMID:11003197   PMID:11042159   PMID:11076861   PMID:11136737   PMID:11217851   PMID:11745664  
PMID:11875023   PMID:12077177   PMID:12169770   PMID:12477932   PMID:12574411   PMID:12808107   PMID:12925894   PMID:14572465   PMID:14715953   PMID:14744041   PMID:15165831   PMID:15207850  
PMID:15229235   PMID:15489334   PMID:15582152   PMID:15610161   PMID:15659595   PMID:15745951   PMID:15850489   PMID:15866052   PMID:15963957   PMID:15978011   PMID:16107646   PMID:16141072  
PMID:16141073   PMID:16436183   PMID:16602821   PMID:16627470   PMID:16927170   PMID:17074040   PMID:17409249   PMID:17442679   PMID:17572671   PMID:17947380   PMID:18281286   PMID:18292084  
PMID:18424167   PMID:18667149   PMID:18790874   PMID:18825662   PMID:18985723   PMID:19204281   PMID:19261880   PMID:19368851   PMID:19578381   PMID:19903874   PMID:20233604   PMID:20412381  
PMID:20519520   PMID:20543135   PMID:20573723   PMID:20579975   PMID:21267068   PMID:21339379   PMID:21789198   PMID:21873635   PMID:21912668   PMID:22357600   PMID:22534482   PMID:22542673  
PMID:22723691   PMID:22768092   PMID:22993424   PMID:23006485   PMID:23069672   PMID:23071808   PMID:23196213   PMID:23337532   PMID:23408872   PMID:23457547   PMID:23616535   PMID:23864689  
PMID:23904597   PMID:23904608   PMID:24068823   PMID:24096136   PMID:24213971   PMID:24217990   PMID:24368169   PMID:24448406   PMID:24843004   PMID:24849349   PMID:24849355   PMID:24952961  
PMID:25010494   PMID:25080584   PMID:25080596   PMID:25107590   PMID:25172774   PMID:25209268   PMID:25251056   PMID:25716832   PMID:25740860   PMID:25891999   PMID:25979088   PMID:26005849  
PMID:26203139   PMID:26221036   PMID:26420868   PMID:26449520   PMID:26655909   PMID:26690700   PMID:27129275   PMID:27340224   PMID:27462076   PMID:27540587   PMID:27652894   PMID:27805050  
PMID:27807161   PMID:27833556   PMID:28195311   PMID:28279354   PMID:28343864   PMID:28505490   PMID:28742937   PMID:28795438   PMID:28816653   PMID:28864826   PMID:29184203   PMID:29302029  
PMID:29463910   PMID:29742426   PMID:29844022   PMID:29875359   PMID:29950725   PMID:30076210   PMID:30121012   PMID:30306129   PMID:30602789   PMID:31087664   PMID:31147611   PMID:31712706  
PMID:31780329   PMID:31910261   PMID:32325033   PMID:32632162   PMID:32732906   PMID:32853550   PMID:32930324   PMID:32944937   PMID:33051462   PMID:33203929   PMID:33582225   PMID:33904401  
PMID:34050134   PMID:34321999   PMID:34341497   PMID:35436993   PMID:35513229   PMID:35874829   PMID:35998632   PMID:36417873   PMID:36604605   PMID:36808153   PMID:36843585   PMID:37703949  
PMID:38187761  


Genomics

Comparative Map Data
Gabrg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391141,801,017 - 41,891,684 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1141,801,030 - 41,891,684 (-)EnsemblGRCm39 Ensembl
GRCm381141,910,190 - 42,000,857 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1141,910,203 - 42,000,857 (-)EnsemblGRCm38mm10GRCm38
MGSCv371141,723,697 - 41,814,180 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361141,753,618 - 41,844,101 (-)NCBIMGSCv36mm8
Celera1145,722,009 - 45,812,211 (-)NCBICelera
Cytogenetic Map11A5NCBI
cM Map1124.8NCBI
GABRG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385162,067,465 - 162,155,539 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5162,000,057 - 162,162,977 (+)EnsemblGRCh38hg38GRCh38
GRCh375161,494,471 - 161,582,545 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365161,427,295 - 161,515,106 (+)NCBINCBI36Build 36hg18NCBI36
Build 345161,427,294 - 161,515,106NCBI
Celera5157,525,645 - 157,613,546 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5156,587,110 - 156,675,113 (+)NCBIHuRef
CHM1_15160,927,088 - 161,014,986 (+)NCBICHM1_1
T2T-CHM13v2.05162,596,314 - 162,684,391 (+)NCBIT2T-CHM13v2.0
Gabrg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81026,876,926 - 26,965,523 (-)NCBIGRCr8
mRatBN7.21026,374,693 - 26,463,937 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1026,374,694 - 26,464,346 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1031,110,673 - 31,199,341 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01030,599,199 - 30,687,869 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01026,085,907 - 26,174,565 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01027,090,913 - 27,179,786 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1027,092,827 - 27,179,900 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01026,934,991 - 27,024,440 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41027,037,561 - 27,126,074 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11027,038,609 - 27,127,123 (-)NCBI
Celera1025,891,936 - 25,979,598 (-)NCBICelera
Cytogenetic Map10q21NCBI
Gabrg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540815,765,984 - 15,857,244 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540815,766,161 - 15,857,121 (+)NCBIChiLan1.0ChiLan1.0
GABRG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24157,231,806 - 157,325,349 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15155,371,352 - 155,472,434 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05157,436,113 - 157,529,586 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15164,135,166 - 164,222,179 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5164,068,122 - 164,222,179 (+)Ensemblpanpan1.1panPan2
GABRG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1448,794,770 - 48,901,859 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl448,796,852 - 48,901,548 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha448,687,383 - 48,794,507 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0449,225,668 - 49,333,872 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl449,225,441 - 49,333,722 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1449,035,654 - 49,142,492 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0449,167,827 - 49,274,742 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0449,689,277 - 49,797,598 (-)NCBIUU_Cfam_GSD_1.0
Gabrg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213103,160,016 - 103,220,841 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365151,607,722 - 1,671,336 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365151,609,370 - 1,670,412 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABRG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1661,441,632 - 61,543,361 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11661,441,622 - 61,543,375 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21666,516,866 - 66,618,887 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GABRG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12364,422,519 - 64,512,124 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2364,422,391 - 64,513,652 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603413,092,532 - 13,182,379 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabrg2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473327,504,660 - 27,594,039 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473327,506,827 - 27,593,750 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gabrg2
3485 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2150
Count of miRNA genes:621
Interacting mature miRNAs:809
Transcripts:ENSMUST00000070725, ENSMUST00000070735, ENSMUST00000109290, ENSMUST00000109292, ENSMUST00000146198
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
1300990Bits3_mbitterness sensitivity 3 (mouse)Not determined11837212142372260Mouse
27226738Metcl11_mmetatarsal-calcaneal length 11, 10 week (mouse)11885000061390826Mouse
1302171Pgia28_mproteoglycan induced arthritis 28 (mouse)Not determined11890609742906218Mouse
4141047Nilac1_mnicotine induced locomotor activity 1 (mouse)Not determined11901178043011942Mouse
13463472Mcvq15_mmean corpuscular volume QTL 15 (mouse)111095123244951464Mouse
13463479Mchq19_mmean corpuscular hemoglobin QTL 19 (mouse)111095123244951464Mouse
26884401Huml4_mhumerus length 4, 10 week (mouse)111155000068490826Mouse
27226762Feml21_mfemur length 21, 16 week (mouse)111175000065990826Mouse
1357640Orq2_movulation rate QTL 2 (mouse)Not determined111226863768500330Mouse
4141127W3q4_mweight 3 weeks QTL 4 (mouse)Not determined1226863768500330Mouse
4141470Egq4_mearly growth QTL 4 (mouse)Not determined1226863768500330Mouse
4142109W10q2_mweight 10 weeks QTL 2 (mouse)Not determined1226863768500330Mouse
4141582Lgaq1_mlate growth adjusted QTL 1 (mouse)Not determined1226863768500330Mouse
4142308W6q3_mweight 6 weeks QTL 3 (mouse)Not determined111226863768500330Mouse
4142216Lgq1_mlate growth QTL 1 (mouse)Not determined1226863768500330Mouse
4141966Tailq1_mtail length QTL 1 (mouse)Not determined1226863768500330Mouse
1357851Scfq3_msubcutaneous fat pad weight QTL 3 (mouse)Not determined111226863768500330Mouse
1357720Kidpq1_mkidney weight percentage QTL 1 (mouse)Not determined111226863768500330Mouse
1357437Epfq4_mepididymal fat pad weight QTL 4 (mouse)Not determined111226863768500330Mouse
1559002Lmrq4_mLeishmania major resistance QTL 4 (mouse)Not determined111226863769684947Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1558945Orgwq8_morgan weight QTL 8 (mouse)Not determined111705617567078411Mouse
10053687Eae6_msusceptibility to experimental allergic encephalomyelitis 6 (mouse)Not determined111778196668500330Mouse
12801459Leuf1_mleukocyte filtration 1 (mouse)111857861652578716Mouse
12801460Intim2_mintima modifier 2 (mouse)111857861652578716Mouse
12801457Intmrm2_mintima/media ratio modifier 2 (mouse)111857861652578716Mouse
1300938Bulb3_mbulb size 3 (mouse)Not determined111857861652578716Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1300579Thypr1_mthymocyte proliferative response 1 (mouse)Not determined111928257753282715Mouse
14746971Manh70_mmandible shape 70 (mouse)111990589053905890Mouse
4141398Tgq22_mtriglyceride QTL 22 (mouse)Not determined2116340655163406Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
10044006Hbnr13_mHeligmosomoides bakeri nematode resistance 13 (mouse)Not determined112577262659772741Mouse
1301814Bbaa7_mB.burgdorferi-associated arthritis 7 (mouse)Not determined112601178044264695Mouse
12910801Pwbwq14_mpost-weaning body weight QTL 14 (mouse)112719805750636094Mouse
12910804Pwbwq16_mpost-weaning body weight QTL 16 (mouse)112719805750636094Mouse
12910806Pwbwq15_mpost-weaning body weight QTL 15 (mouse)112719805750636094Mouse
12910817Pwgrq20_mpost-weaning growth rate QTL 20 (mouse)112719805750636094Mouse
12910818Ogrq5_moverall growth rate QTL 5 (mouse)112719805750636094Mouse
1357844Si5lq5_mserum IGFBP-5 level QTL 5 (mouse)Not determined112816587362165976Mouse
13524848Ppiq7_mprepulse inhibition QTL 7 (mouse)112856914762569147Mouse
1301426Desp2_mdespair 2 (mouse)Not determined112870858162708700Mouse
11522752Cocia18_mcocaine-induced activity, QTL 18 (mouse)113100820965008209Mouse
11059563Lmr31_mleishmaniasis resistance 31 (mouse)113210057766100694Mouse
10043922Alcw9_malcohol withdrawal 9 (mouse)Not determined113557861644065931Mouse
1301718Pbw3_mpentobarbital withdrawal QTL 3 (mouse)Not determined113557861644065931Mouse
1558769Zolw1_mzolpidem withdrawal 1 (mouse)Not determined113557861644065931Mouse
1357782Char8_mP. chabaudi malaria resistance QTL 8 (mouse)Not determined113557861669684987Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
4142475Ity2a_mimmunity to S. typhimurium 2a (mouse)Not determined113776858060402716Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
10053675Eae44b_mexperimental allergic encephalomyelitis susceptibility 44b (mouse)Not determined113995072854094448Mouse

Markers in Region
BB314104  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381141,911,417 - 41,911,538UniSTSGRCm38
MGSCv371141,724,919 - 41,725,040UniSTSGRCm37
Celera1145,723,231 - 45,723,352UniSTS
Cytogenetic Map11A5UniSTS
cM Map1119.0UniSTS
Whitehead/MRC_RH16818.44UniSTS
M62374  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381141,912,041 - 41,912,226UniSTSGRCm38
MGSCv371141,725,543 - 41,725,728UniSTSGRCm37
Celera1145,723,855 - 45,724,040UniSTS
Cytogenetic Map11A5UniSTS
cM Map1119.0UniSTS
Whitehead_YAC11 UniSTS
Gabrg2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A5UniSTS
cM Map1119.0UniSTS
AI851231  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381141,912,022 - 41,912,115UniSTSGRCm38
MGSCv371141,725,524 - 41,725,617UniSTSGRCm37
Celera1145,723,836 - 45,723,929UniSTS
Cytogenetic Map11A5UniSTS
cM Map1119.0UniSTS
Whitehead/MRC_RH11567.24UniSTS
Whitehead/MRC_RH11568.65UniSTS
Gabrg2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A5UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001362655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_177408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030245561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF233775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233783 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233800 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF233802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK034338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK047085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK136889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX284629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M62374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M86572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X56311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X56313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000070725   ⟹   ENSMUSP00000064739
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1141,801,030 - 41,891,684 (-)Ensembl
GRCm38.p6 Ensembl1141,910,203 - 42,000,857 (-)Ensembl
RefSeq Acc Id: ENSMUST00000070735   ⟹   ENSMUSP00000063812
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1141,802,536 - 41,891,359 (-)Ensembl
GRCm38.p6 Ensembl1141,911,709 - 42,000,532 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109290   ⟹   ENSMUSP00000104913
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1141,805,394 - 41,891,183 (-)Ensembl
GRCm38.p6 Ensembl1141,914,567 - 42,000,356 (-)Ensembl
RefSeq Acc Id: ENSMUST00000146198
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1141,802,538 - 41,807,450 (-)Ensembl
GRCm38.p6 Ensembl1141,911,711 - 41,916,623 (-)Ensembl
RefSeq Acc Id: NM_001362655   ⟹   NP_001349584
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391141,801,017 - 41,891,684 (-)NCBI
GRCm381141,910,190 - 42,000,857 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001362656   ⟹   NP_001349585
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391141,801,017 - 41,891,684 (-)NCBI
GRCm381141,910,190 - 42,000,857 (-)NCBI
Sequence:
RefSeq Acc Id: NM_008073   ⟹   NP_032099
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391141,801,017 - 41,891,684 (-)NCBI
GRCm381141,910,190 - 42,000,857 (-)NCBI
MGSCv371141,723,697 - 41,814,180 (-)RGD
Celera1145,722,004 - 45,812,247 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_177408   ⟹   NP_803127
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391141,801,017 - 41,891,684 (-)NCBI
GRCm381141,910,190 - 42,000,857 (-)NCBI
MGSCv371141,723,697 - 41,814,180 (-)RGD
Celera1145,722,004 - 45,812,247 (-)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030245561   ⟹   XP_030101421
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391141,801,021 - 41,891,666 (-)NCBI
GRCm381141,910,194 - 42,000,839 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036156333   ⟹   XP_036012226
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391141,801,021 - 41,891,667 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001349584 (Get FASTA)   NCBI Sequence Viewer  
  NP_001349585 (Get FASTA)   NCBI Sequence Viewer  
  NP_032099 (Get FASTA)   NCBI Sequence Viewer  
  NP_803127 (Get FASTA)   NCBI Sequence Viewer  
  XP_030101421 (Get FASTA)   NCBI Sequence Viewer  
  XP_036012226 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA37653 (Get FASTA)   NCBI Sequence Viewer  
  AAB59635 (Get FASTA)   NCBI Sequence Viewer  
  AAH31762 (Get FASTA)   NCBI Sequence Viewer  
  AAK71573 (Get FASTA)   NCBI Sequence Viewer  
  AAK71574 (Get FASTA)   NCBI Sequence Viewer  
  AAK71575 (Get FASTA)   NCBI Sequence Viewer  
  AAK71576 (Get FASTA)   NCBI Sequence Viewer  
  AAK71577 (Get FASTA)   NCBI Sequence Viewer  
  AAK71578 (Get FASTA)   NCBI Sequence Viewer  
  AAK71579 (Get FASTA)   NCBI Sequence Viewer  
  AAK71580 (Get FASTA)   NCBI Sequence Viewer  
  AAK71581 (Get FASTA)   NCBI Sequence Viewer  
  AAK71582 (Get FASTA)   NCBI Sequence Viewer  
  AAK71583 (Get FASTA)   NCBI Sequence Viewer  
  AAK71584 (Get FASTA)   NCBI Sequence Viewer  
  AAK71585 (Get FASTA)   NCBI Sequence Viewer  
  AAK71586 (Get FASTA)   NCBI Sequence Viewer  
  AAK71587 (Get FASTA)   NCBI Sequence Viewer  
  AAK71588 (Get FASTA)   NCBI Sequence Viewer  
  AAK71589 (Get FASTA)   NCBI Sequence Viewer  
  AAK71590 (Get FASTA)   NCBI Sequence Viewer  
  AAK71591 (Get FASTA)   NCBI Sequence Viewer  
  AAK71592 (Get FASTA)   NCBI Sequence Viewer  
  AAK71593 (Get FASTA)   NCBI Sequence Viewer  
  AAK71594 (Get FASTA)   NCBI Sequence Viewer  
  AAK71595 (Get FASTA)   NCBI Sequence Viewer  
  AAK71596 (Get FASTA)   NCBI Sequence Viewer  
  AAK71597 (Get FASTA)   NCBI Sequence Viewer  
  AAK71598 (Get FASTA)   NCBI Sequence Viewer  
  AAK71599 (Get FASTA)   NCBI Sequence Viewer  
  AAK71600 (Get FASTA)   NCBI Sequence Viewer  
  BAC32956 (Get FASTA)   NCBI Sequence Viewer  
  BAC33961 (Get FASTA)   NCBI Sequence Viewer  
  BAE23157 (Get FASTA)   NCBI Sequence Viewer  
  EDL32338 (Get FASTA)   NCBI Sequence Viewer  
  EDL32339 (Get FASTA)   NCBI Sequence Viewer  
  EDL32340 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000063812
  ENSMUSP00000063812.3
  ENSMUSP00000064739
  ENSMUSP00000064739.5
  ENSMUSP00000104913.2
GenBank Protein P22723 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_803127   ⟸   NM_177408
- Peptide Label: isoform 2 precursor
- UniProtKB: Q3UVW2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_032099   ⟸   NM_008073
- Peptide Label: isoform 1 precursor
- UniProtKB: Q91V50 (UniProtKB/Swiss-Prot),   Q91VA8 (UniProtKB/Swiss-Prot),   P22723 (UniProtKB/Swiss-Prot),   Q8C8H5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001349584   ⟸   NM_001362655
- Peptide Label: isoform 3 precursor
- UniProtKB: Q8C8H5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001349585   ⟸   NM_001362656
- Peptide Label: isoform 4 precursor
- UniProtKB: Q8C8H5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030101421   ⟸   XM_030245561
- Peptide Label: isoform X2
- UniProtKB: Q3UVW2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000063812   ⟸   ENSMUST00000070735
RefSeq Acc Id: ENSMUSP00000064739   ⟸   ENSMUST00000070725
RefSeq Acc Id: ENSMUSP00000104913   ⟸   ENSMUST00000109290
RefSeq Acc Id: XP_036012226   ⟸   XM_036156333
- Peptide Label: isoform X1
- UniProtKB: Q3UVW2 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P22723-F1-model_v2 AlphaFold P22723 1-474 view protein structure

Promoters
RGD ID:8674320
Promoter ID:EPDNEW_M15190
Type:initiation region
Name:Gabrg2_2
Description:Mus musculus gamma-aminobutyric acid A receptor, subunit gamma2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15191  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381142,000,569 - 42,000,629EPDNEW
RGD ID:8674322
Promoter ID:EPDNEW_M15191
Type:multiple initiation site
Name:Gabrg2_1
Description:Mus musculus gamma-aminobutyric acid A receptor, subunit gamma2 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M15190  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381142,000,794 - 42,000,854EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95623 AgrOrtholog
Ensembl Genes ENSMUSG00000020436 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000070725 ENTREZGENE
  ENSMUST00000070725.11 UniProtKB/Swiss-Prot
  ENSMUST00000070735 ENTREZGENE
  ENSMUST00000070735.10 UniProtKB/Swiss-Prot
  ENSMUST00000109290.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.390 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.70.170.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GABAA/Glycine_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABBAg2_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABBAg_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_channel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro-gated_channel_TM_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neuro_actylchol_rec UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotrans-gated_channel_TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neurotransmitter_ion_chnl_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14406 UniProtKB/Swiss-Prot
MGD MGI:95623 ENTREZGENE
NCBI Gene 14406 ENTREZGENE
PANTHER GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18945 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Neur_chan_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB GABRG2 RGD
PhenoGen Gabrg2 PhenoGen
PRINTS GABAARECEPTR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABAARGAMMA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABAARGAMMA2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NRIONCHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE NEUROTR_ION_CHANNEL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF63712 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt GBRG2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UVW2 ENTREZGENE, UniProtKB/TrEMBL
  Q8C7N0_MOUSE UniProtKB/TrEMBL
  Q8C8H5 ENTREZGENE, UniProtKB/TrEMBL
  Q91V50 ENTREZGENE
  Q91VA8 ENTREZGENE
UniProt Secondary Q91V50 UniProtKB/Swiss-Prot
  Q91VA8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Gabrg2  gamma-aminobutyric acid type A receptor, subunit gamma 2  Gabrg2  gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2  Symbol and/or name change 5135510 APPROVED