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Gene: Ano6 (anoctamin 6) Mus musculus
Symbol: Ano6
Name: anoctamin 6
Description: Exhibits gated channel activity; phospholipid scramblase activity; and protein homodimerization activity. Involved in several processes, including calcium activated phospholipid scrambling; inorganic ion transmembrane transport; and positive regulation of transport. Localizes to the integral component of plasma membrane. Human ortholog(s) of this gene implicated in Scott syndrome; ankylosing spondylitis; and inflammatory bowel disease. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and viscerocranium. Orthologous to human ANO6 (anoctamin 6); INTERACTS WITH (-)-epigallocatechin 3-gallate; 3,4-methylenedioxymethamphetamine; 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900059G15Rik; AA407480; anoctamin-6; AW554778; F730003B03Rik; SCAN channel; small-conductance calcium-activated nonselective cation channel; Tmem16f; transmembrane protein 16F
Homo sapiens (human) : ANO6 (anoctamin 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ano6 (anoctamin 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ano6 (anoctamin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ANO6 (anoctamin 6)
Canis lupus familiaris (dog) : ANO6 (anoctamin 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ano6 (anoctamin 6)
Sus scrofa (pig) : ANO6 (anoctamin 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1595,790,843 - 95,974,751 (+)Ensembl
GRCm381595,790,843 - 95,975,472 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371595,621,274 - 95,805,205 (+)NCBIGRCm37mm9NCBIm37
MGSCv361595,618,877 - 95,802,808 (+)NCBImm8
Celera1597,939,179 - 98,119,566 (+)NCBICelera
Cytogenetic Map15 E3-F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ano6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312399
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.