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Gene: Ano6 (anoctamin 6) Mus musculus
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Symbol: Ano6
Name: anoctamin 6
Description: Exhibits gated channel activity; phospholipid scramblase activity; and protein homodimerization activity. Involved in several processes, including calcium activated phospholipid scrambling; inorganic ion transmembrane transport; and positive regulation of transport. Localizes to the integral component of plasma membrane. Human ortholog(s) of this gene implicated in Scott syndrome; ankylosing spondylitis; and inflammatory bowel disease. Is expressed in several structures, including alimentary system; nervous system; respiratory system; sensory organ; and viscerocranium. Orthologous to human ANO6 (anoctamin 6); INTERACTS WITH (-)-epigallocatechin 3-gallate; 3,4-methylenedioxymethamphetamine; 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2900059G15Rik; AA407480; anoctamin-6; AW554778; F730003B03Rik; SCAN channel; small-conductance calcium-activated nonselective cation channel; Tmem16f; transmembrane protein 16F
Orthologs:
Homo sapiens (human) : ANO6 (anoctamin 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ano6 (anoctamin 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ano6 (anoctamin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ANO6 (anoctamin 6)
Canis lupus familiaris (dog) : ANO6 (anoctamin 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ano6 (anoctamin 6)
Sus scrofa (pig) : ANO6 (anoctamin 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1595,790,843 - 95,974,751 (+)Ensembl
GRCm381595,790,843 - 95,975,472 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371595,621,274 - 95,805,205 (+)NCBIGRCm37mm9NCBIm37
MGSCv361595,618,877 - 95,802,808 (+)NCBImm8
Celera1597,939,179 - 98,119,566 (+)NCBICelera
Cytogenetic Map15 E3-F1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ano6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312399
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.