Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | increases expression | ISO | GABRP (Homo sapiens) | 6480464 | Demecolcine results in increased expression of GABRP mRNA | CTD | PMID:23649840 | 1,2-dichloroethane | decreases expression | EXP | | 6480464 | ethylene dichloride results in decreased expression of GABRP mRNA | CTD | PMID:28960355 | 17alpha-ethynylestradiol | affects expression | ISO | GABRP (Homo sapiens) | 6480464 | Ethinyl Estradiol affects the expression of GABRP mRNA | CTD | PMID:20170705 | 17alpha-ethynylestradiol | decreases expression | ISO | GABRP (Homo sapiens) | 6480464 | Ethinyl Estradiol results in decreased expression of GABRP mRNA | CTD | PMID:18936297 | 17alpha-ethynylestradiol | decreases expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in decreased expression of GABRP mRNA | CTD | PMID:17351261 | 17alpha-ethynylestradiol | increases expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in increased expression of GABRP mRNA | CTD | PMID:17557909 | 17alpha-ethynylestradiol | affects expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | Ethinyl Estradiol affects the expression of GABRP mRNA | CTD | PMID:20170705 | 17beta-estradiol | affects expression | ISO | GABRP (Homo sapiens) | 6480464 | Estradiol affects the expression of GABRP mRNA | CTD | PMID:16000229 | 17beta-estradiol | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of GABRP mRNA and [Estradiol results in increased activity of ESR1 protein] which results in decreased expression of GABRP mRNA | CTD | PMID:20660070 and PMID:22403704 | 17beta-estradiol | increases expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | Estradiol results in increased expression of GABRP mRNA | CTD | PMID:17010207 | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:27291303 | 2,2',5,5'-tetrachlorobiphenyl | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to GABRP promoter] | CTD | PMID:19654925 | aflatoxin B1 | increases methylation | ISO | GABRP (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of GABRP gene | CTD | PMID:27153756 | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GABRP mRNA | CTD | PMID:37567420 | all-trans-retinoic acid | decreases expression | ISO | GABRP (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of GABRP mRNA | CTD | PMID:21934132 | all-trans-retinoic acid | increases expression | ISO | GABRP (Homo sapiens) | 6480464 | Tretinoin results in increased expression of GABRP mRNA | CTD | PMID:16249480 and PMID:23830798 | ammonium chloride | affects expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of GABRP mRNA | CTD | PMID:16483693 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to GABRP promoter] | CTD | PMID:19654925 | benzo[a]pyrene | affects methylation | ISO | GABRP (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of GABRP promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | GABRP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of GABRP 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of GABRP mRNA | CTD | PMID:22228805 | benzo[b]fluoranthene | decreases expression | EXP | | 6480464 | benzo(b)fluoranthene results in decreased expression of GABRP mRNA | CTD | PMID:26377693 | bis(2-ethylhexyl) phthalate | increases expression | ISO | GABRP (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of GABRP mRNA | CTD | PMID:31163220 | bisphenol A | affects expression | ISO | GABRP (Homo sapiens) | 6480464 | bisphenol A affects the expression of GABRP mRNA | CTD | PMID:20170705 | bisphenol A | decreases expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of GABRP mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | [bisphenol A results in increased activity of ESR1 protein] which results in decreased expression of GABRP mRNA | CTD | PMID:22403704 | bisphenol A | decreases expression | ISO | GABRP (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of GABRP mRNA | CTD | PMID:20678512 | bisphenol F | increases expression | EXP | | 6480464 | bisphenol F results in increased expression of GABRP mRNA | CTD | PMID:30951980 | cadmium atom | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GABRP mRNA | CTD | PMID:35301059 | cadmium dichloride | increases expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | Cadmium Chloride results in increased expression of GABRP mRNA | CTD | PMID:33453195 | cadmium dichloride | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of GABRP mRNA | CTD | PMID:35301059 | calcitriol | increases expression | ISO | GABRP (Homo sapiens) | 6480464 | Calcitriol results in increased expression of GABRP mRNA | CTD | PMID:26485663 | carbon nanotube | affects expression | EXP | | 6480464 | Nanotubes and Carbon analog affects the expression of GABRP mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to GABRP gene] | CTD | PMID:28238834 | chlordecone | increases expression | EXP | | 6480464 | Chlordecone results in increased expression of GABRP mRNA | CTD | PMID:33711761 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of GABRP mRNA | CTD | PMID:20938992 | clothianidin | decreases expression | EXP | | 6480464 | clothianidin results in decreased expression of GABRP mRNA | CTD | PMID:35264496 | copper atom | increases expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | Copper results in increased expression of GABRP mRNA | CTD | PMID:30556269 | copper(0) | increases expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | Copper results in increased expression of GABRP mRNA | CTD | PMID:30556269 | cordycepin | decreases expression | ISO | GABRP (Homo sapiens) | 6480464 | cordycepin results in decreased expression of GABRP mRNA | CTD | PMID:34858524 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of GABRP mRNA | CTD | PMID:19770486 | cytarabine | increases expression | ISO | GABRP (Homo sapiens) | 6480464 | Cytarabine results in increased expression of GABRP mRNA | CTD | PMID:21198554 | D-glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GABRP mRNA | CTD | PMID:37567420 | DDT | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | [DDT results in increased activity of ESR1 protein] which results in decreased expression of GABRP mRNA | CTD | PMID:22403704 | diethylstilbestrol | increases expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | Diethylstilbestrol results in increased expression of GABRP mRNA | CTD | PMID:17010207 | dioxygen | multiple interactions | EXP | | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of GABRP mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | finasteride | decreases expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | Finasteride results in decreased expression of GABRP protein | CTD | PMID:27750143 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of GABRP mRNA | CTD | PMID:20938992 | folic acid | increases expression | EXP | | 6480464 | Folic Acid results in increased expression of GABRP mRNA | CTD | PMID:25629700 | formaldehyde | increases expression | ISO | GABRP (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of GABRP mRNA | CTD | PMID:23649840 | fructose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GABRP mRNA | CTD | PMID:37567420 | furan | increases methylation | ISO | Gabrp (Rattus norvegicus) | 6480464 | furan results in increased methylation of GABRP gene | CTD | PMID:22079235 | genistein | decreases expression | EXP | | 6480464 | Genistein results in decreased expression of GABRP mRNA | CTD | PMID:32186404 | glucose | multiple interactions | EXP | | 6480464 | [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in increased expression of GABRP mRNA | CTD | PMID:37567420 | inulin | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of GABRP mRNA | CTD | PMID:36331819 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of GABRP mRNA | CTD | PMID:20938992 | mercury dibromide | increases expression | ISO | GABRP (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of GABRP mRNA | CTD | PMID:26272509 | mercury dibromide | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GABRP mRNA | CTD | PMID:27188386 | methotrexate | affects expression | EXP | | 6480464 | Methotrexate affects the expression of GABRP mRNA | CTD | PMID:18502557 | naphthalene | decreases expression | EXP | | 6480464 | naphthalene results in decreased expression of GABRP mRNA | CTD | PMID:18757308 | nickel atom | decreases expression | ISO | GABRP (Homo sapiens) | 6480464 | Nickel results in decreased expression of GABRP mRNA | CTD | PMID:24768652 and PMID:25583101 | ozone | multiple interactions | EXP | | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of GABRP mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of GABRP mRNA | CTD | PMID:34911549 | panobinostat | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GABRP mRNA | CTD | PMID:27188386 | PCB138 | multiple interactions | EXP | | 6480464 | [2 more ... | CTD | PMID:25510870 | perfluorohexanesulfonic acid | decreases expression | EXP | | 6480464 | perfluorohexanesulfonic acid results in decreased expression of GABRP mRNA | CTD | PMID:37995155 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of GABRP mRNA | CTD | PMID:36331819 | progesterone | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in decreased expression of GABRP mRNA more ... | CTD | PMID:20103740 and PMID:20660070 | progesterone | decreases expression | EXP | | 6480464 | Progesterone results in decreased expression of GABRP mRNA | CTD | PMID:22238285 | progesterone | increases expression | ISO | GABRP (Homo sapiens) | 6480464 | Progesterone results in increased expression of GABRP mRNA | CTD | PMID:20103740 | progesterone | affects localization | ISO | GABRP (Homo sapiens) | 6480464 | Progesterone affects the localization of GABRP protein | CTD | PMID:20103740 | SB 431542 | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | decreases expression | ISO | GABRP (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of GABRP mRNA | CTD | PMID:28595984 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of GABRP mRNA | CTD | PMID:37682722 | sodium arsenite | affects expression | ISO | GABRP (Homo sapiens) | 6480464 | sodium arsenite affects the expression of GABRP mRNA | CTD | PMID:34032870 | tebuconazole | decreases expression | ISO | GABRP (Homo sapiens) | 6480464 | tebuconazole results in decreased expression of GABRP mRNA | CTD | PMID:30458266 | titanium dioxide | affects expression | EXP | | 6480464 | titanium dioxide affects the expression of GABRP mRNA | CTD | PMID:17656681 and PMID:23557971 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of GABRP mRNA | CTD | PMID:29264374 | tremolite asbestos | increases expression | EXP | | 6480464 | tremolite results in increased expression of GABRP mRNA | CTD | PMID:29279043 | trichloroethene | increases expression | ISO | Gabrp (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of GABRP mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | GABRP (Homo sapiens) | 6480464 | trichostatin A results in increased expression of GABRP mRNA | CTD | PMID:24935251 | valproic acid | decreases methylation | ISO | GABRP (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of GABRP gene | CTD | PMID:29154799 | valproic acid | multiple interactions | ISO | GABRP (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of GABRP mRNA | CTD | PMID:27188386 | valproic acid | increases expression | ISO | GABRP (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of GABRP mRNA | CTD | PMID:24383497 more ... | zinc atom | increases expression | EXP | | 6480464 | Zinc deficiency results in increased expression of GABRP mRNA | CTD | PMID:20857495 | zinc(0) | increases expression | EXP | | 6480464 | Zinc deficiency results in increased expression of GABRP mRNA | CTD | PMID:20857495 | zoledronic acid | decreases expression | ISO | GABRP (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of GABRP mRNA | CTD | PMID:24714768 | |