Gabra5 (gamma-aminobutyric acid type A receptor subunit alpha 5) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Gabra5 (gamma-aminobutyric acid type A receptor subunit alpha 5) Mus musculus
Analyze
Symbol: Gabra5
Name: gamma-aminobutyric acid type A receptor subunit alpha 5
RGD ID: 62151
MGI Page MGI
Description: Enables GABA-A receptor activity and GABA-gated chloride ion channel activity. Involved in cochlea development; inner ear receptor cell development; and innervation. Acts upstream of or within associative learning and behavioral fear response. Located in cell body and dendrite. Is expressed in brain and palatal shelf. Human ortholog(s) of this gene implicated in bipolar disorder; depressive disorder; and developmental and epileptic encephalopathy 79. Orthologous to human GABRA5 (gamma-aminobutyric acid type A receptor subunit alpha5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A230018I05Rik; GABA(A) receptor subunit alpha-5; GABAA receptor alpha5 subunit; GABAAR subunit alpha-5; gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5; gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5; gamma-aminobutyric acid receptor subunit alpha-5; ligand-gated ion channel subunit
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39757,057,417 - 57,240,808 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl757,057,420 - 57,159,807 (-)EnsemblGRCm39 Ensembl
GRCm38757,407,669 - 57,591,016 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl757,407,672 - 57,510,059 (-)EnsemblGRCm38mm10GRCm38
MGSCv37764,663,039 - 64,765,379 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36757,275,688 - 57,377,873 (-)NCBIMGSCv36mm8
Celera754,720,522 - 54,830,242 (-)NCBICelera
Cytogenetic Map7B5NCBI
cM Map733.52NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. mRNA and protein levels for GABAAalpha4, alpha5, beta1 and GABABR1 receptors are altered in brains from subjects with autism. Fatemi SH, etal., J Autism Dev Disord. 2010 Jun;40(6):743-50.
2. Excess of allele1 for alpha3 subunit GABA receptor gene (GABRA3) in bipolar patients: a multicentric association study. Massat I, etal., Mol Psychiatry 2002;7(2):201-7.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. Positive association between the GABRA5 gene and unipolar recurrent major depression. Oruc L, etal., Neuropsychobiology 1997;36(2):62-4.
7. Association between the GABA(A) receptor alpha5 subunit gene locus (GABRA5) and bipolar affective disorder. Papadimitriou GN, etal., Am J Med Genet 1998 Feb 7;81(1):73-80.
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1338907   PMID:2561977   PMID:7560270   PMID:7601451   PMID:8001787   PMID:8146195   PMID:8388764   PMID:8389098   PMID:8389469   PMID:8392662   PMID:8601494   PMID:8889548  
PMID:9060416   PMID:9330366   PMID:9682826   PMID:9729294   PMID:9924185   PMID:10349636   PMID:10479684   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11745664   PMID:12084936  
PMID:12097508   PMID:12477932   PMID:14993607   PMID:15263904   PMID:15282283   PMID:15284346   PMID:15380015   PMID:15456818   PMID:15489334   PMID:15549469   PMID:15620220   PMID:16141072  
PMID:16141073   PMID:16253225   PMID:16452257   PMID:16467845   PMID:16597725   PMID:16870734   PMID:16987237   PMID:17021187   PMID:17525114   PMID:17638582   PMID:17715197   PMID:18077674  
PMID:18185516   PMID:18256262   PMID:18287559   PMID:19457072   PMID:19941877   PMID:20180861   PMID:20392949   PMID:20457185   PMID:21048709   PMID:21070817   PMID:21677750   PMID:21712993  
PMID:21825029   PMID:21862448   PMID:21873635   PMID:22514301   PMID:22569571   PMID:22640814   PMID:22677273   PMID:22723691   PMID:22768092   PMID:22999935   PMID:23516534   PMID:24952961  
PMID:25100596   PMID:25365226   PMID:25708312   PMID:25865415   PMID:25891999   PMID:26134653   PMID:26169564   PMID:26322928   PMID:26446222   PMID:27067130   PMID:27155990   PMID:27364953  
PMID:27779093   PMID:27792253   PMID:27793660   PMID:28717969   PMID:30104684   PMID:30121012   PMID:30177704   PMID:30282698   PMID:30523065   PMID:31665922   PMID:32750173   PMID:32877400  
PMID:33068001   PMID:33096025   PMID:34530841   PMID:35228700   PMID:36120438   PMID:36417873   PMID:36733270   PMID:36833213   PMID:38187761   PMID:38355793   PMID:38736483   PMID:38894703  


Genomics

Comparative Map Data
Gabra5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39757,057,417 - 57,240,808 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl757,057,420 - 57,159,807 (-)EnsemblGRCm39 Ensembl
GRCm38757,407,669 - 57,591,016 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl757,407,672 - 57,510,059 (-)EnsemblGRCm38mm10GRCm38
MGSCv37764,663,039 - 64,765,379 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36757,275,688 - 57,377,873 (-)NCBIMGSCv36mm8
Celera754,720,522 - 54,830,242 (-)NCBICelera
Cytogenetic Map7B5NCBI
cM Map733.52NCBI
GABRA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381526,866,719 - 26,949,208 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1526,866,911 - 26,949,208 (+)EnsemblGRCh38hg38GRCh38
GRCh371527,111,866 - 27,194,355 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361524,663,151 - 24,679,797 (+)NCBINCBI36Build 36hg18NCBI36
Build 361524,742,696 - 24,776,749 (+)NCBINCBI36Build 36hg18NCBI36
Build 341524,742,694 - 24,776,749NCBI
Celera155,273,203 - 5,355,540 (+)NCBICelera
Cytogenetic Map15q12NCBI
HuRef155,288,011 - 5,322,374 (+)NCBIHuRef
HuRef155,241,009 - 5,262,207 (+)NCBIHuRef
CHM1_11527,061,401 - 27,143,890 (+)NCBICHM1_1
T2T-CHM13v2.01524,607,751 - 24,690,792 (+)NCBIT2T-CHM13v2.0
Gabra5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81117,404,446 - 117,517,424 (-)NCBIGRCr8
mRatBN7.21108,268,728 - 108,381,670 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1108,268,776 - 108,380,917 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1113,646,984 - 113,751,778 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01122,119,493 - 122,224,279 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01115,367,807 - 115,472,601 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01112,833,941 - 112,947,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1112,833,944 - 112,947,451 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01113,844,235 - 113,955,760 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41108,843,086 - 108,955,130 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11108,921,428 - 109,033,473 (-)NCBI
Celera1102,441,576 - 102,547,389 (-)NCBICelera
Cytogenetic Map1q22NCBI
Gabra5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555332,563,319 - 2,631,289 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555332,563,499 - 2,631,086 (-)NCBIChiLan1.0ChiLan1.0
GABRA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2168,328,194 - 8,411,167 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11511,969,290 - 12,052,259 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0152,953,857 - 3,036,722 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11524,300,300 - 24,382,535 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1524,300,300 - 24,382,730 (+)Ensemblpanpan1.1panPan2
GABRA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1333,663,414 - 33,746,120 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl333,664,169 - 33,744,328 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha336,353,800 - 36,436,241 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0333,999,325 - 34,081,790 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl333,999,318 - 34,081,948 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1333,539,876 - 33,622,259 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0333,802,491 - 33,884,937 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0333,949,742 - 34,032,243 (-)NCBIUU_Cfam_GSD_1.0
Gabra5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640121,933,396 - 122,009,905 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647139,781,451 - 39,975,518 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647139,781,451 - 39,856,766 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GABRA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1140,486,104 - 140,567,894 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11140,486,107 - 140,568,204 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21156,791,330 - 156,874,272 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GABRA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12655,147,512 - 55,227,801 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2655,147,511 - 55,227,297 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605437,978,006 - 38,060,544 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gabra5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248961,267,077 - 1,337,038 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:250
Count of miRNA genes:202
Interacting mature miRNAs:221
Transcripts:ENSMUST00000068456
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
27226778Femd11_mfemur midshaft diameter 11, 16 week (mouse)756949748134001729Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
25823170Hrsq7_mhost response to SARS QTL 7, log titer (mouse)754819589116822815Mouse
1357469Kidq5_mkidney weight QTL 5 (mouse)Not determined73349772758148965Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
4142003W3q10_mweight 3 weeks QTL 10 (mouse)Not determined3349772758148965Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
1357634Splq7_mspleen weight QTL 7 (mouse)Not determined73349772758148965Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1300878Skts1_mskin tumor susceptibility 1 (mouse)Not determined73789138671891582Mouse
11565101Tsve1_mvariable short tail (Tsv) enhancer 1 (mouse)75588950887142720Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753249748143153737Mouse
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
13208555Lgth10_mbody length 10 (mouse)751649748125599172Mouse
1301175Ap7q_malcohol preference 7 QTL (mouse)Not determined73171484565715077Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
12880417V125Dq5_mvitamin D active form serum level QTL 5 (mouse)74524974879249748Mouse
10402488Dipa2_mdrug induced psychomotor activation 2 (mouse)Not determined73842154872421684Mouse
12880418V125Dq6_mvitamin D active form serum level QTL 6 (mouse)75214974886149748Mouse
4142102Tailq5_mtail length QTL 5 (mouse)Not determined3349772758148965Mouse
10054064Bwq11_mbody weight QTL 11 (mouse)Not determined75112495485125093Mouse
4141909W10q18_mweight 10 weeks QTL 18 (mouse)Not determined3349772758148965Mouse
11532741Tbrs5_mtuberculosis resistance 5 (mouse)74915922783235415Mouse
1357752Tabw_mtally ho asscoiated body weight (mouse)Not determined74919327883193390Mouse
10053685Eae43_mexperimental allergic encephalomyelitis susceptibility 43 (mouse)Not determined75112495485125093Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1302141Fcsa6_mfemoral cross-sectional area 6 (mouse)Not determined74838446182384607Mouse
1357883Epfq5_mepididymal fat pad weight QTL 5 (mouse)Not determined73349772758148965Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
4142218W6q17_mweight 6 weeks QTL 17 (mouse)Not determined3349772758148965Mouse
12738423Lfibq6_mliver fibrosis QTL 6 (mouse)74769437866704862Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
25314302Vmm2_mvariable multisystem mineralization 2, heart (mouse)74714974874149748Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
25314301Vmm3_mvariable multisystem mineralization 3, lung (mouse)73729942572049748Mouse

Markers in Region
AW046005  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38757,407,922 - 57,408,009UniSTSGRCm38
MGSCv37764,663,292 - 64,663,379UniSTSGRCm37
Celera754,720,775 - 54,720,862UniSTS
Cytogenetic Map7CUniSTS
cM Map728.5UniSTS
Whitehead/MRC_RH7682.38UniSTS
14.MMHAP22FRE8.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38757,417,953 - 57,418,107UniSTSGRCm38
MGSCv37764,673,323 - 64,673,477UniSTSGRCm37
Cytogenetic Map7CUniSTS
cM Map728.5UniSTS
Whitehead_YAC7 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001362161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001362162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_176942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006540556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006540557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006540560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030241988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC102129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC109157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC160553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF090374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF540386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000068456   ⟹   ENSMUSP00000063276
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl757,057,420 - 57,159,757 (-)Ensembl
GRCm38.p6 Ensembl757,407,672 - 57,510,009 (-)Ensembl
Ensembl Acc Id: ENSMUST00000206382   ⟹   ENSMUSP00000146238
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl757,057,467 - 57,159,119 (-)Ensembl
GRCm38.p6 Ensembl757,407,719 - 57,509,371 (-)Ensembl
Ensembl Acc Id: ENSMUST00000206734   ⟹   ENSMUSP00000145685
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl757,057,653 - 57,159,807 (-)Ensembl
GRCm38.p6 Ensembl757,407,905 - 57,510,059 (-)Ensembl
RefSeq Acc Id: NM_001362161   ⟹   NP_001349090
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39757,057,417 - 57,159,807 (-)NCBI
GRCm38757,407,669 - 57,510,059 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001362162   ⟹   NP_001349091
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39757,057,417 - 57,159,757 (-)NCBI
GRCm38757,407,669 - 57,510,009 (-)NCBI
Sequence:
RefSeq Acc Id: NM_176942   ⟹   NP_795916
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39757,057,417 - 57,159,757 (-)NCBI
GRCm38757,407,669 - 57,510,009 (-)NCBI
MGSCv37764,663,039 - 64,765,379 (-)RGD
Celera754,720,522 - 54,830,242 (-)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006540556   ⟹   XP_006540619
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39757,057,420 - 57,159,381 (-)NCBI
GRCm38757,407,672 - 57,509,637 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006540557   ⟹   XP_006540620
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39757,057,420 - 57,159,382 (-)NCBI
GRCm38757,407,683 - 57,509,638 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006540560   ⟹   XP_006540623
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39757,057,420 - 57,159,856 (-)NCBI
GRCm38757,407,672 - 57,510,103 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030241988   ⟹   XP_030097848
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39757,057,420 - 57,240,808 (-)NCBI
GRCm38757,407,672 - 57,591,016 (-)NCBI
Sequence:
RefSeq Acc Id: NP_795916   ⟸   NM_176942
- Peptide Label: precursor
- UniProtKB: Q8BHJ7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006540623   ⟸   XM_006540560
- Peptide Label: isoform X1
- UniProtKB: Q8BHJ7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006540620   ⟸   XM_006540557
- Peptide Label: isoform X1
- UniProtKB: Q8BHJ7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006540619   ⟸   XM_006540556
- Peptide Label: isoform X1
- UniProtKB: Q8BHJ7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001349090   ⟸   NM_001362161
- Peptide Label: precursor
- UniProtKB: Q8BHJ7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001349091   ⟸   NM_001362162
- Peptide Label: precursor
- UniProtKB: Q8BHJ7 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_030097848   ⟸   XM_030241988
- Peptide Label: isoform X1
- UniProtKB: Q8BHJ7 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSMUSP00000145685   ⟸   ENSMUST00000206734
Ensembl Acc Id: ENSMUSP00000146238   ⟸   ENSMUST00000206382
Ensembl Acc Id: ENSMUSP00000063276   ⟸   ENSMUST00000068456
Protein Domains
Neurotransmitter-gated ion-channel ligand-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8BHJ7-F1-model_v2 AlphaFold Q8BHJ7 1-463 view protein structure

Promoters
RGD ID:8664267
Promoter ID:EPDNEW_M10165
Type:initiation region
Name:Gabra5_1
Description:Mus musculus gamma-aminobutyric acid A receptor, subunit alpha5 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38757,509,922 - 57,509,982EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95617 AgrOrtholog
Ensembl Genes ENSMUSG00000055078 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000068456 ENTREZGENE
  ENSMUST00000068456.8 UniProtKB/Swiss-Prot
  ENSMUST00000206382 ENTREZGENE
  ENSMUST00000206382.2 UniProtKB/Swiss-Prot
  ENSMUST00000206734 ENTREZGENE
  ENSMUST00000206734.2 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.58.390 UniProtKB/Swiss-Prot
  2.70.170.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GABAA/Glycine_rcpt UniProtKB/Swiss-Prot
  GABAAa_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABBAa5_rcpt UniProtKB/Swiss-Prot
  Gabra-1-6_TM UniProtKB/Swiss-Prot
  Neur_chan_lig-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_lig-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_channel UniProtKB/Swiss-Prot
  Neuro-gated_channel_TM_sf UniProtKB/Swiss-Prot
  Neuro_actylchol_rec UniProtKB/Swiss-Prot
  Neurotrans-gated_channel_TM UniProtKB/Swiss-Prot
  Neurotransmitter_ion_chnl_CS UniProtKB/Swiss-Prot
KEGG Report mmu:110886 UniProtKB/Swiss-Prot
MGD MGI:95617 ENTREZGENE
NCBI Gene Gabra5 ENTREZGENE
PANTHER GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-5 UniProtKB/Swiss-Prot
  PTHR18945 UniProtKB/Swiss-Prot
Pfam Neur_chan_LBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Neur_chan_memb UniProtKB/Swiss-Prot
PhenoGen Gabra5 PhenoGen
PRINTS GABAARALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GABAARALPHA5 UniProtKB/Swiss-Prot
  GABAARECEPTR UniProtKB/Swiss-Prot
  NRIONCHANNEL UniProtKB/Swiss-Prot
PROSITE NEUROTR_ION_CHANNEL UniProtKB/Swiss-Prot
Superfamily-SCOP SSF63712 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF90112 UniProtKB/Swiss-Prot
UniProt GBRA5_MOUSE UniProtKB/Swiss-Prot
  O88964_MOUSE UniProtKB/TrEMBL
  Q8BHJ7 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Gabra5  gamma-aminobutyric acid type A receptor subunit alpha 5  Gabra5  gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5  Symbol and/or name change 5135510 APPROVED
2024-08-21 Gabra5  gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 5  Gabra5  gamma-aminobutyric acid type A receptor subunit alpha 5  Symbol and/or name change 5135510 APPROVED
2023-07-04 Gabra5  gamma-aminobutyric acid type A receptor subunit alpha 5  Gabra5  gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5  Symbol and/or name change 5135510 APPROVED