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Gene: GABRA5 (gamma-aminobutyric acid type A receptor alpha5 subunit) Homo sapiens
Symbol: GABRA5
Name: gamma-aminobutyric acid type A receptor alpha5 subunit
Description: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: GABA(A) receptor subunit alpha-5; GABA(A) receptor, alpha 5; gamma-aminobutyric acid (GABA) A receptor, alpha 5; gamma-aminobutyric acid receptor subunit alpha-5; MGC138184
Allele / Splice: See ClinVar data
Is Marker For: QTLs:   BW330_H  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381526,866,719 - 26,949,210 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371527,111,866 - 27,194,357 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361524,663,151 - 24,679,797 (+)NCBINCBI36hg18NCBI36
Build 361524,742,696 - 24,776,749 (+)NCBINCBI36hg18NCBI36
Build 341524,742,694 - 24,776,749NCBI
Celera155,273,203 - 5,355,540 (+)NCBI
Cytogenetic Map15q12NCBI
HuRef155,288,011 - 5,322,374 (+)NCBIHuRef
HuRef155,241,009 - 5,262,207 (+)NCBIHuRef
CHM1_11527,061,401 - 27,143,890 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GABRA5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736048
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-07-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.